Minna Laitinen
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View article: What is debridement, antibiotics, and implant retention in orthopaedic oncology?
What is debridement, antibiotics, and implant retention in orthopaedic oncology? Open
Aims Following resection of a primary bone tumour, reconstruction is commonly performed using either a megaprosthesis or biological reconstruction. Periprosthetic joint infection (PJI) remains one of the most frequent complications. Variou…
View article: Androgen deprivation therapy and overall survival after hip fracture surgery in patients with prostate cancer
Androgen deprivation therapy and overall survival after hip fracture surgery in patients with prostate cancer Open
Background and aims: Androgen deprivation therapy (ADT), either by surgical or chemical castration, is the standard treatment for metastatic prostate cancer (PCa). ADT induces osteoporosis and increases the risk of osteoporotic fractures, …
View article: Prediction of patient-reported outcomes after proximal humerus fractures in elderly patients does not appear to be a credible option
Prediction of patient-reported outcomes after proximal humerus fractures in elderly patients does not appear to be a credible option Open
Aims The aim of this study was to investigate which patient- and fracture-related factors predict functional outcome at two years in patients aged 60 years or older with a proximal humerus fracture, and to assess the possible evidence in f…
View article: Metastatic bone disease in proximal femur. Outcome of surgical treatments. − Do we know what to do?
Metastatic bone disease in proximal femur. Outcome of surgical treatments. − Do we know what to do? Open
View article: Nonoperative treatment versus volar locking plating for distal radius fracture in patients aged 65 years or older (DRIFT trial): A randomized controlled trial
Nonoperative treatment versus volar locking plating for distal radius fracture in patients aged 65 years or older (DRIFT trial): A randomized controlled trial Open
Background The optimal management of distal radius fractures (DRFs) in older patients remains debatable. A knowledge gap exists concerning how to manage fractures with early malalignment during nonoperative treatment. We conducted a prospe…
View article: Improving oncological outcomes for pelvic bone sarcomas: Is it possible?
Improving oncological outcomes for pelvic bone sarcomas: Is it possible? Open
Advances in centralization, and technical advances have significantly improved local control and survival, particularly for chondrosarcoma and sacral chordoma. However, outcomes for osteosarcoma and ES remain constrained, highlighting the …
View article: Surgical treatment of monostotic fibrous dysplasia of the proximal femur in children and adolescents: Observational European Paediatric Orthopaedic Society multicenter study
Surgical treatment of monostotic fibrous dysplasia of the proximal femur in children and adolescents: Observational European Paediatric Orthopaedic Society multicenter study Open
Purpose: Monostotic fibrous dysplasia is a rare benign fibro-osseous disorder. Proximal femoral monostotic fibrous dysplasia is especially vulnerable to pathological fracture and deformation, requiring specific treatment strategies. Litera…
View article: Traumatic hemipelvectomy: an appeal for primary completion
Traumatic hemipelvectomy: an appeal for primary completion Open
View article: Global and regional disparities in access to specialist sarcoma services
Global and regional disparities in access to specialist sarcoma services Open
Aims Cancer care guidelines have been developed in many subspecialities, usually in advanced health systems. However, there are notable global disparities in healthcare access, which can impact sarcoma care. Unfortunately, there is a lack …
View article: Identifying consensus and areas for future research in chondrosarcoma
Identifying consensus and areas for future research in chondrosarcoma Open
Aims The Birmingham Orthopaedic Oncology Meeting (BOOM), held in January 2024, convened 309 delegates from 53 countries to discuss and refine 21 consensus statements on the optimal management of chondrosarcoma. Methods With representation …
View article: Controversies in orthopaedic oncology
Controversies in orthopaedic oncology Open
Chondrosarcoma is the second most common surgically treated primary bone sarcoma. Despite a large number of scientific papers in the literature, there is still significant controversy about diagnostics, treatment of the primary tumour, sub…
View article: Can the Cartilaginous Thickness Determine the Risk of Malignancy in Pelvic Cartilaginous Tumors, and How Accurate is the Preoperative Biopsy of These Tumors?
Can the Cartilaginous Thickness Determine the Risk of Malignancy in Pelvic Cartilaginous Tumors, and How Accurate is the Preoperative Biopsy of These Tumors? Open
Background Peripheral osteochondral tumors are common, and the management of tumors presenting in the pelvis is challenging and a controversial topic. Some have suggested that cartilage cap thickness may indicate malignant potential, but t…
View article: CORR Insights®: How Does Customized Cutting Guide Design Affect Accuracy and Ergonomics in Pelvic Tumor Resection? A Study in Cadavers
CORR Insights®: How Does Customized Cutting Guide Design Affect Accuracy and Ergonomics in Pelvic Tumor Resection? A Study in Cadavers Open
1Head of the Orthopaedic and Traumatology Department, Helsinki University Central Hospital, Helsinki, Finland M. K. Laitinen, Department of Orthopaedics and Traumatology, Helsinki University Hospital, Haartmaninkatu 4, 00290 Helsinki, Finl…
View article: Chondrosarcoma of the Femur: Is Local Recurrence Influenced by the Presence of an Extraosseous Component?
Chondrosarcoma of the Femur: Is Local Recurrence Influenced by the Presence of an Extraosseous Component? Open
Background: Chondrosarcoma (CS) is the second most common surgically treated primary malignancy of the bone. The current study explored the effect of the margin and extraosseous tumor component in CS in the femur on local recurrence (LR), …
View article: As simple as it sounds? The treatment of simple bone cysts in the proximal femur in children and adolescents: Retrospective multicenter EPOS study of 74 patients
As simple as it sounds? The treatment of simple bone cysts in the proximal femur in children and adolescents: Retrospective multicenter EPOS study of 74 patients Open
Purpose: Simple bone cysts are among the most prevalent benign cystic tumor-like lesions in children. Proximal femoral simple bone cysts may require specific treatment because of increased fracture risk. With limited literature available o…
View article: Surgery with locking plate or hemiarthroplasty versus nonoperative treatment of 3–4-part proximal humerus fractures in older patients (NITEP): An open-label randomized trial
Surgery with locking plate or hemiarthroplasty versus nonoperative treatment of 3–4-part proximal humerus fractures in older patients (NITEP): An open-label randomized trial Open
Background Proximal humerus fractures (PHFs) are common fractures, especially in older female patients. These fractures are commonly treated surgically, but the consensus on the best treatment is still lacking. Methods and findings The pri…
View article: Enchondroma Detection from Hand Radiographs with an Interactive Deep Learning Segmentation Tool—A Feasibility Study
Enchondroma Detection from Hand Radiographs with an Interactive Deep Learning Segmentation Tool—A Feasibility Study Open
Enchondromas are common benign bone tumors, usually presenting in the hand. They can cause symptoms such as swelling and pain but often go un-noticed. If the tumor expands, it can diminish the bone cortices and predispose the bone to fract…
View article: Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations
Intraosseous conventional central chondrosarcoma does not metastasise irrespective of grade in pelvis, scapula and in long bone locations Open
View article: Case report and review: Angiosarcoma with thrombocytopenia after total hip arthroplasty
Case report and review: Angiosarcoma with thrombocytopenia after total hip arthroplasty Open
Total hip arthroplasty (THA) is a common treatment for osteoarthritis and is also performed for other conditions, such as secondary arthritis due to developmental dysplasia of the hip. Various THA types may be complicated by osteolysis and…
View article: Pelvic bone sarcomas, prognostic factors, and treatment: A narrative review of the literature
Pelvic bone sarcomas, prognostic factors, and treatment: A narrative review of the literature Open
Primary sarcomas of bone are rare malignant mesenchymal tumors. The most common bone sarcomas are osteosarcoma, Ewing’s sarcoma, and chondrosarcoma. The prognosis has improved over the years, but bone sarcomas are still life-threatening tu…
View article: Chondrosarcoma of the Proximal Humerus: Does the Margin Affect Survival?
Chondrosarcoma of the Proximal Humerus: Does the Margin Affect Survival? Open
Chondrosarcoma (CS) is the second most common primary malignant bone tumour and, in the absence of reliable chemotherapy and radiotherapy, is effectively a surgical disease. Overall disease specific survival (DSS) is affected by tumour gra…
View article: A comparison of the functional results and costs of functional cast and volar-flexion ulnar deviation cast at 2-year follow-up in 105 patients aged 65 and older with dorsally displaced distal radius fracture: A randomized controlled trial
A comparison of the functional results and costs of functional cast and volar-flexion ulnar deviation cast at 2-year follow-up in 105 patients aged 65 and older with dorsally displaced distal radius fracture: A randomized controlled trial Open
Background and purpose Non-operative treatment is the most common treatment option for older patients with distal radius fracture (DRF). Traditionally, wrists have been placed in volar-flexion and ulnar deviation position (VFUDC). In recen…
View article: Mortality following proximal humerus fracture—a nationwide register study of 147,692 fracture patients in Sweden
Mortality following proximal humerus fracture—a nationwide register study of 147,692 fracture patients in Sweden Open
The mortality rate and SMR suggest that PHF patients are heterogeneous. Some older PHF patients may benefit from specialized care (e.g., orthogeriatric), and this should be evaluated in future studies.
View article: Preoperative coagulation biomarkers associate with survival and pulmonary embolism after surgical treatment of non-spinal skeletal metastases
Preoperative coagulation biomarkers associate with survival and pulmonary embolism after surgical treatment of non-spinal skeletal metastases Open
View article: Do’s and Don’ts in Primary Aneurysmal Bone Cysts of the Proximal Femur in Children and Adolescents: Retrospective Multicenter EPOS Study of 79 Patients
Do’s and Don’ts in Primary Aneurysmal Bone Cysts of the Proximal Femur in Children and Adolescents: Retrospective Multicenter EPOS Study of 79 Patients Open
Background: Aneurysmal bone cysts (ABC) are rare benign cystic bone tumors, generally diagnosed in children and adolescents. Proximal femoral ABCs may require specific treatment strategies because of an increased pathologic fracture risk. …
View article: Surgical and patient-reported outcomes after total knee arthroplasty requiring soft tissue flap reconstruction – A 12-year experience from high-volume arthroplasty hospital
Surgical and patient-reported outcomes after total knee arthroplasty requiring soft tissue flap reconstruction – A 12-year experience from high-volume arthroplasty hospital Open
Both the SNC and EC groups had similar acceptable limb salvage rates, and functional and PROM outcomes. Infection reduces the probability of a functional knee joint after TKA and flap reconstruction.
View article: The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC
The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC Open
View article: Corrigendum to ‘Age-related differences of oncological outcomes in primary extremity soft tissue sarcoma: a multistate model including 6260 patients’ [Eur J Cancer 141 (2020) 128-136]
Corrigendum to ‘Age-related differences of oncological outcomes in primary extremity soft tissue sarcoma: a multistate model including 6260 patients’ [Eur J Cancer 141 (2020) 128-136] Open
View article: The impact of full-thickness rotator cuff tear on shoulder function and quality of life in patients who sustain a proximal humerus fracture—a prospective cohort study
The impact of full-thickness rotator cuff tear on shoulder function and quality of life in patients who sustain a proximal humerus fracture—a prospective cohort study Open
View article: Measuring functional outcome in upper extremity soft-tissue sarcoma: Validation of the Toronto extremity salvage score and the QuickDASH patient-reported outcome instruments
Measuring functional outcome in upper extremity soft-tissue sarcoma: Validation of the Toronto extremity salvage score and the QuickDASH patient-reported outcome instruments Open
Interest in functional outcome (FO) and health-related quality of life (HRQL) in extremity soft-tissue sarcoma (STS) patients has increased. The aim of this study was to validate two FO questionnaires for upper extremity STS patients: the …