Minodora Teodoru
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View article: Gut Microbiota-Derived Metabolites in Atherosclerosis: Pathways, Biomarkers, and Targets
Gut Microbiota-Derived Metabolites in Atherosclerosis: Pathways, Biomarkers, and Targets Open
The human gut microbiota is a complex ecosystem that influences host metabolism, immune function, and cardiovascular health. Dysbiosis, defined as an imbalance in microbial composition or function, has been linked to the development and pr…
View article: OCT for Optimizing Long-Term Clinical Results in Left Main PCI—Dream or Reality? Results from a Single-Center High-Volume Registry
OCT for Optimizing Long-Term Clinical Results in Left Main PCI—Dream or Reality? Results from a Single-Center High-Volume Registry Open
Background: With growing evidence regarding long-term clinical results of left main angioplasty, it has become clear that the gap between percutaneous coronary interventions (PCIs) and bypass surgery can be narrowed only by improving the P…
View article: Intersecting Pathways: The Impact of Philadelphia-Negative Chronic Myeloproliferative Neoplasms on the Pathogenesis and Progression of Heart Failure with Preserved Ejection Fraction
Intersecting Pathways: The Impact of Philadelphia-Negative Chronic Myeloproliferative Neoplasms on the Pathogenesis and Progression of Heart Failure with Preserved Ejection Fraction Open
Background: Heart failure with preserved ejection fraction (HFpEF) is increasingly prevalent worldwide due to ageing and comorbidities. Emerging evidence suggests that Philadelphia-negative chronic myeloproliferative neoplasms (MPNs), part…
View article: Gut Microbiota - Derived Metabolites in Atherosclerosis: Pathways, Biomarkers, and Targets
Gut Microbiota - Derived Metabolites in Atherosclerosis: Pathways, Biomarkers, and Targets Open
This review aims to analyze the critical role of gut microbiota-derived metabolites in the pathogenesis of atherosclerosis, a chronic inflammatory disease driven by lipid accumulation and immune dysregulation, and a leading cause of cardio…
View article: Galectin-3 Reflects Systemic Atherosclerosis in Patients with Coronary Artery Disease
Galectin-3 Reflects Systemic Atherosclerosis in Patients with Coronary Artery Disease Open
Background and Objectives: Galectin-3 (Gal-3), a pro-inflammatory cytokine, has been implicated in atherosclerosis and adverse cardiovascular outcomes. While its role in coronary artery disease (CAD) is increasingly recognized, its associa…
View article: The Role of HSP47 in Thrombotic Disorders: Molecular Mechanism and Therapeutic Potential
The Role of HSP47 in Thrombotic Disorders: Molecular Mechanism and Therapeutic Potential Open
This review aims to analyze the role of heat shock protein 47 (HSP47) in thrombosis and evaluate its potential as a therapeutic target for deep vein thrombosis (DVT). A systematic literature review was conducted using PubMed, Scopus, and W…
View article: A Unique Case of Extramedullary Relapse in Acute Lymphoblastic Leukemia: Testicular to Ocular, Cardiac, and Colonic Involvement and the Role of Sperm Phenotyping in Diagnosis—Case Report and Literature Review
A Unique Case of Extramedullary Relapse in Acute Lymphoblastic Leukemia: Testicular to Ocular, Cardiac, and Colonic Involvement and the Role of Sperm Phenotyping in Diagnosis—Case Report and Literature Review Open
Acute lymphoblastic leukemia (ALL) is a malignant condition of lymphoid progenitor cells that primarily affects the pediatric population, but also adults. The 5-year survival rate is 90% in children and approximately 40% in adults, with su…
View article: A case report of Ebstein’s anomaly–Gerbode defect dyad: is there room for another anomaly in the same patient?
A case report of Ebstein’s anomaly–Gerbode defect dyad: is there room for another anomaly in the same patient? Open
Background Ebstein’s anomaly is a rare congenital heart disease characterized by apical displacement of the septal and posterior tricuspid valve leaflets. It is commonly associated with other defects such as patent foramen ovale or accesso…
View article: Heart Rate Recovery: Up to Date in Heart Failure—A Literature Review
Heart Rate Recovery: Up to Date in Heart Failure—A Literature Review Open
The rising prevalence of cardiovascular disease underscores the growing significance of heart failure (HF). Pathophysiological insights into HF highlight the dysregulation of the autonomic nervous system (ANS), characterized by sympathetic…
View article: Assessing Lifestyle Patterns and Their Influence on Weight Status in Students from a High School in Sibiu, Romania: An Adaptation of ISCOLE Questionnaires and the Child Feeding Questionnaire
Assessing Lifestyle Patterns and Their Influence on Weight Status in Students from a High School in Sibiu, Romania: An Adaptation of ISCOLE Questionnaires and the Child Feeding Questionnaire Open
The escalation of global obesity is driving research to understand environmental influences on this process, particularly during vulnerable developmental stages such as childhood and adolescence. Efforts include the development of various …
View article: Enhancing Pulmonary Embolism Mortality Risk Stratification Using Machine Learning: The Role of the Neutrophil-to-Lymphocyte Ratio
Enhancing Pulmonary Embolism Mortality Risk Stratification Using Machine Learning: The Role of the Neutrophil-to-Lymphocyte Ratio Open
(1) Background: Acute pulmonary embolism (PE) is a significant public health concern that requires efficient risk estimation to optimize patient care and resource allocation. The purpose of this retrospective study was to show the correlat…
View article: Assessing Obesogenic School Environments in Sibiu County, Romania: Adapting the ISCOLE School Environment Questionnaire
Assessing Obesogenic School Environments in Sibiu County, Romania: Adapting the ISCOLE School Environment Questionnaire Open
The impact of the school environment on childhood weight status has garnered significant attention in recent years. This study aimed to adapt and validate the International Study of Childhood Obesity, Lifestyle and the Environment (ISCOLE)…
View article: Interactions between Metabolic Syndrome, MASLD, and Arterial Stiffening: A Single-Center Cross-Sectional Study
Interactions between Metabolic Syndrome, MASLD, and Arterial Stiffening: A Single-Center Cross-Sectional Study Open
Metabolic-associated steatotic liver disease (MASLD), previously termed non-alcoholic fatty liver disease (NAFLD), has emerged as a prominent global cause of chronic liver disease and is increasingly recognized as associated with atheroscl…
View article: IGF-1 Levels are Dependent on Age, but Not Weight Status in Children
IGF-1 Levels are Dependent on Age, but Not Weight Status in Children Open
Introduction: The intersecting pathways involved in linear growth, glucose, and lipid metabolism may play a key part in the imbalances leading to the dysmetabolic changes observed in obese children, and later adults. The growth-horm…
View article: Hepatic Involvement across the Metabolic Syndrome Spectrum: Non-Invasive Assessment and Risk Prediction Using Machine Learning
Hepatic Involvement across the Metabolic Syndrome Spectrum: Non-Invasive Assessment and Risk Prediction Using Machine Learning Open
Metabolic-dysfunction-associated steatotic liver disease (MASLD) and metabolic syndrome (MetS) are inextricably linked conditions, both of which are experiencing an upward trend in prevalence, thereby exerting a substantial clinical and ec…
View article: A Family with Myh7 Mutation and Different Forms of Cardiomyopathies
A Family with Myh7 Mutation and Different Forms of Cardiomyopathies Open
Background: Hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) are common heart muscle disorders that are caused by pathogenic variants in sarcomere protein genes. In this study, we describe a variant in the MHY7 gene, segr…
View article: Endocarditis with Streptococcus pseudoporcinus Associated with Mastocytosis and Spondylodiscitis—A Coincidental Association? A Case Report
Endocarditis with Streptococcus pseudoporcinus Associated with Mastocytosis and Spondylodiscitis—A Coincidental Association? A Case Report Open
Streptococcus pseudoporcinus is a nonmotile Gram-positive, catalase, and benzidine negative, arranged in short chains, isolated from the genitourinary tract group B Streptococcus. S. pseudoporcinus was also identified from blood, urine, sk…
View article: Post-Marketing Surveillance of Statins—A Descriptive Analysis of Psychiatric Adverse Reactions in EudraVigilance
Post-Marketing Surveillance of Statins—A Descriptive Analysis of Psychiatric Adverse Reactions in EudraVigilance Open
Statins are included in the category of high-frequency prescription drugs, and their use is on an upward trend worldwide. In 2012, the FDA issued a warning about possible cognitive adverse drug reactions (ADRs) related to statins, some of …
View article: Retracted: Poster No. 022 Partial atresia of the inferior vena cava associated with deep vein thrombosis – case report
Retracted: Poster No. 022 Partial atresia of the inferior vena cava associated with deep vein thrombosis – case report Open
This abstract has been withdrawn. Please see: https://doi.org/10.1093/cvr/cvac183
View article: Gender Particularities and Prevalence of Atypical Clinical Presentation in Non-ST Elevation Acute Coronary Syndrome
Gender Particularities and Prevalence of Atypical Clinical Presentation in Non-ST Elevation Acute Coronary Syndrome Open
Clinical presentation is one of the factors that can influence how quickly a patient with an acute coronary syndrome is treated, particularly if it is atypical. The purposes of this study are to explore gender-related differences in patien…
View article: Causative Mechanisms of Childhood and Adolescent Obesity Leading to Adult Cardiometabolic Disease: A Literature Review
Causative Mechanisms of Childhood and Adolescent Obesity Leading to Adult Cardiometabolic Disease: A Literature Review Open
The past few decades have shown a worrisome increase in the prevalence of obesity and its related illnesses. This increasing burden has a noteworthy impact on overall worldwide mortality and morbidity, with significant economic implication…
View article: The Role of Cardiac Magnetic Resonance in Patients with Dilated Cardiomiopathy
The Role of Cardiac Magnetic Resonance in Patients with Dilated Cardiomiopathy Open
Dilated cardiomyopathy (DCM) has an increased risk of heart failure, malignant ventricular arrhythmias, including sudden cardiac death, being the most common cause of heart transplantation. Cardiac magnetic resonance imaging (CMR) is the g…
View article: A Decision-Tree Approach to Assist in Forecasting the Outcomes of the Neonatal Brain Injury
A Decision-Tree Approach to Assist in Forecasting the Outcomes of the Neonatal Brain Injury Open
Neonatal brain injury or neonatal encephalopathy (NE) is a significant morbidity and mortality factor in preterm and full-term newborns. NE has an incidence in the range of 2.5 to 3.5 per 1000 live births carrying a considerable burden for…
View article: Individual Alpha Peak Frequency, an Important Biomarker for Live Z-Score Training Neurofeedback in Adolescents with Learning Disabilities
Individual Alpha Peak Frequency, an Important Biomarker for Live Z-Score Training Neurofeedback in Adolescents with Learning Disabilities Open
Learning disabilities (LDs) have an estimated prevalence between 5% and 9% in the pediatric population and are associated with difficulties in reading, arithmetic, and writing. Previous electroencephalography (EEG) research has reported a …
View article: The Influence of Risk Factors on the Choice of Therapeutic Method in Peripheral Arterial Disease
The Influence of Risk Factors on the Choice of Therapeutic Method in Peripheral Arterial Disease Open
Peripheral arterial disease (PAD) is characterized by obstruction in the lower limbs, mainly due to atherosclerosis. The prevalence of the pathology in people under 40 years of age is 6% and 15-20% in the population over 65 years old.(1,2)…
View article: Principles of Rhythm Management in Patients with Atrial Fibrillation
Principles of Rhythm Management in Patients with Atrial Fibrillation Open
Atrial fibrillation is a multilateral arrhythmia, which causes the clinician to encounter difficulties in its therapeutic approach for each new patient. The purpose of this paper aims in particular at evaluating the management of atrial fi…
View article: Risk Factors in Peripheral Artery Disease Associated with Coronary Artery Disease
Risk Factors in Peripheral Artery Disease Associated with Coronary Artery Disease Open
Peripheral arterial disease (PAD) is a partial or complete occlusion of one or more arteries leading to a suppression of blood flow and ischemia. In the process of stenosis, numerous processes are described, among which, the most common be…
View article: New Approach in Ocular Involvement of Chronic Treatment with Amiodarone
New Approach in Ocular Involvement of Chronic Treatment with Amiodarone Open
Significance: The results of the study will reveal the main risks of ocular alterations in patients treated with Amiodarone, regarding visual acuity, contrast sensitivity, keratometry, visual field, ocular pressure, Schirmer Test, tear bre…