Minxiu Wang
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View article: Felodipine Promotes the Recovery of Mice With Spinal Cord Injury by Activating Macrolipophagy Through the <scp>AMPK</scp>‐<scp>mTOR</scp> Pathway
Felodipine Promotes the Recovery of Mice With Spinal Cord Injury by Activating Macrolipophagy Through the <span>AMPK</span>‐<span>mTOR</span> Pathway Open
Spinal cord injury (SCI) is a serious clinical condition characterised by extensive mechanical damage that compromises the tissue structure and microenvironment of the affected area. This damage leads to the formation of fibrotic blood ves…
View article: Inhibition of MD2 by natural product-drived JM-9 attenuates renal inflammation and diabetic nephropathy in mice
Inhibition of MD2 by natural product-drived JM-9 attenuates renal inflammation and diabetic nephropathy in mice Open
Diabetic kidney disease (DKD) is one of the severe complications of diabetes mellitus-related microvascular lesions, which remains the leading cause of end-stage kidney disease. The genesis and development of DKD is closely related to infl…
View article: Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway
Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway Open
View article: OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes
OTUD1 promotes pathological cardiac remodeling and heart failure by targeting STAT3 in cardiomyocytes Open
Rationale: Understanding the molecular mechanisms of deleterious cardiac remodeling is important for the development of treatments for heart failure. Recent studies have highlighted a role of deubiquitinating enzymes in cardiac path…
View article: Curcumin analog JM-2 alleviates diabetic cardiomyopathy inflammation and remodeling by inhibiting the NF-κB pathway
Curcumin analog JM-2 alleviates diabetic cardiomyopathy inflammation and remodeling by inhibiting the NF-κB pathway Open
Cardiac inflammation is an important pathological process in diabetic cardiomyopathy (DCM). Curcumin is a natural compound found in the rhizome of Curcuma longa and has been shown to possess multifunctional bioactivities. In the present st…
View article: Diacerein protects liver against APAP-induced injury via targeting JNK and inhibiting JNK-mediated oxidative stress and apoptosis
Diacerein protects liver against APAP-induced injury via targeting JNK and inhibiting JNK-mediated oxidative stress and apoptosis Open
View article: Genome Wide Association Study of Body Size Traits in Multiple Varieties of Yak Based on the Provided Compressed Mixed Linear Model
Genome Wide Association Study of Body Size Traits in Multiple Varieties of Yak Based on the Provided Compressed Mixed Linear Model Open
View article: Curcumin analogue C66 attenuates obesity-induced myocardial injury by inhibiting JNK-mediated inflammation
Curcumin analogue C66 attenuates obesity-induced myocardial injury by inhibiting JNK-mediated inflammation Open
Obesity has been recognized as a major risk factor for the development of chronic cardiomyopathy, which is associated with increased cardiac inflammation, fibrosis, and apoptosis. We previously developed an anti-inflammatory compound C66, …
View article: Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
View article: Additional file 2 of Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Additional file 2 of Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
Additional file 2.
View article: Additional file 1 of Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Additional file 1 of Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
Additional file 1.
View article: Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
Background: Lesion mimics (LM) is a disease-like symptom randomly spread on plant green leaves without any pathogens. Previous study has found that LM was related to enhanced resistance to a broad spectrum of diverse pathogen races and pro…
View article: Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
Background Lesion mimics (LM) is a disease-like symptom randomly spread on plant green leaves without any pathogens. Previous study has found that LM was related to enhanced resistance to a broad spectrum of diverse pathogen races and prog…
View article: Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat
Molecular mapping of a novel lesion mimic gene (lm4) associated with enhanced resistance to stripe rust in bread wheat Open
Background: Lesion mimics (LM) is a disease-like symptom randomly spread on plant green leaves without any pathogens. Previous study has found that LM was related to enhanced resistance to a broad spectrum of diverse pathogen races and pro…
View article: A parallel genome-wide RNAi screening strategy to identify host proteins important for entry of Marburg virus and H5N1 influenza virus
A parallel genome-wide RNAi screening strategy to identify host proteins important for entry of Marburg virus and H5N1 influenza virus Open
This strategy is particularly useful for highly pathogenic viruses since pseudotyping allows us to perform high throughput screens in the biosafety level 2 (BSL-2) containment instead of the BSL-3 or BSL-4 for the infectious viruses, with …
View article: Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry
Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry Open
Filoviruses, including both Ebola virus (EBOV) and Marburg virus (MARV), can infect humans and other animals, causing hemorrhagic fever with a high mortality rate. Entry of these viruses into the host is mediated by a single filoviral glyc…