Mireia Urpí-Sardá
YOU?
Author Swipe
View article: Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro
Blood serum from individuals with Alzheimer’s disease alters microglial phagocytosis in vitro Open
In Alzheimer’s disease, microglial phagocytosis is engaged in the pathogenesis as it clears abnormal protein accumulations, debris, and apoptotic cells in the early stages of Alzheimer’s disease, but fuels neuroinflammation and accelerates…
View article: The Power of Databases in Unraveling the Nutrition–Health Connection
The Power of Databases in Unraveling the Nutrition–Health Connection Open
Human activities across different sectors produce large volumes of relevant nutritional information [...]
View article: Influence of Dietary Intake on Carotid Maximum Intima–Media Thickness in Children Conceived Through Assisted Reproductive Techniques
Influence of Dietary Intake on Carotid Maximum Intima–Media Thickness in Children Conceived Through Assisted Reproductive Techniques Open
Background/Objectives: Research on the relationship between nutritional characteristics and their impact on cardiovascular remodeling in children conceived by assisted reproductive technology (ART) is limited. We aimed to explore the influ…
View article: Volumetric brain reductions in adult patients with phenylketonuria and their relationship with blood phenylalanine levels
Volumetric brain reductions in adult patients with phenylketonuria and their relationship with blood phenylalanine levels Open
View article: Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice
Coffee polyphenols ameliorate early-life stress-induced cognitive deficits in male mice Open
Stress exposure during the sensitive period of early development has been shown to program the brain and increases the risk to develop cognitive deficits later in life. We have shown earlier that early-life stress (ES) leads to cognitive d…
View article: Association of dietary and nutritional factors with cognitive decline, dementia, and depressive symptomatology in older individuals according to a neurogenesis-centred biological susceptibility to brain ageing
Association of dietary and nutritional factors with cognitive decline, dementia, and depressive symptomatology in older individuals according to a neurogenesis-centred biological susceptibility to brain ageing Open
Hippocampal neurogenesis (HN) occurs throughout the life course and is important for memory and mood. Declining with age, HN plays a pivotal role in cognitive decline (CD), dementia, and late-life depression, such that altered HN could rep…
View article: A Mediterranean Diet‐Based Metabolomic Score and Cognitive Decline in Older Adults: A Case–Control Analysis Nested within the Three‐City Cohort Study
A Mediterranean Diet‐Based Metabolomic Score and Cognitive Decline in Older Adults: A Case–Control Analysis Nested within the Three‐City Cohort Study Open
Scope Evidence on the Mediterranean diet (MD) and age‐related cognitive decline (CD) is still inconclusive partly due to self‐reported dietary assessment. The aim of the current study is to develop an MD‐ metabolomic score (MDMS) and inves…
View article: Effect of Special Low-Protein Foods Consumption in the Dietary Pattern and Biochemical Profile of Patients with Inborn Errors of Protein Metabolism: Application of a Database of Special Low-Protein Foods
Effect of Special Low-Protein Foods Consumption in the Dietary Pattern and Biochemical Profile of Patients with Inborn Errors of Protein Metabolism: Application of a Database of Special Low-Protein Foods Open
In inborn errors of intermediate protein metabolism (IEM), the effect of special low-protein foods (SLPFs) on dietary intake has been scarcely studied. The aim of this study was to compare the nutritional profile of SLPFs with usual foods …
View article: Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial
Adherence to Mediterranean Diet and Response to an Exercise Program to Prevent Hospitalization-Associated Disability in Older Adults: A Secondary Analysis from a Randomized Controlled Trial Open
Older individuals over age 75 with low MedDiet adherence were likely to benefit more from a physical exercise and health education intervention.
View article: Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons
Exploration of the Gut–Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons Open
The gut microbiome is involved in nutrient metabolism and produces metabolites that, via the gut–brain axis, signal to the brain and influence cognition. Human studies have so far had limited success in identifying early metabolic alterati…
View article: Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study
Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study Open
View article: Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline
Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline Open
View article: Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12‐Year Prospective Study
Food and Microbiota Metabolites Associate with Cognitive Decline in Older Subjects: A 12‐Year Prospective Study Open
Scope Diet is considered an important modulator of cognitive decline and dementia, but the available evidence is, however, still fragmented and often inconsistent. Methods and Results The article studies the long‐term prospective Three‐Cit…
View article: The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia
The serum metabolome mediates the concert of diet, exercise, and neurogenesis, determining the risk for cognitive decline and dementia Open
Introduction Diet and exercise influence the risk of cognitive decline (CD) and dementia through the food metabolome and exercise‐triggered endogenous factors, which use the blood as a vehicle to communicate with the brain. These factors m…
View article: The 3-Year Effect of the Mediterranean Diet Intervention on Inflammatory Biomarkers Related to Cardiovascular Disease
The 3-Year Effect of the Mediterranean Diet Intervention on Inflammatory Biomarkers Related to Cardiovascular Disease Open
The intervention with the Mediterranean diet (MD) pattern has evidenced short-term anti-inflammatory effects, but little is known about its long-term anti-inflammatory properties at molecular level. This study aims to investigate the 3-yea…
View article: Effect of COVID-19 Lockdown on Dietary Habits and Lifestyle of Food Science Students and Professionals from Spain
Effect of COVID-19 Lockdown on Dietary Habits and Lifestyle of Food Science Students and Professionals from Spain Open
On 11 March 2020, the World Health Organization (WHO) declared COVID-19 a global pandemic, forcing countries around the world to confine their population to halt the rapid spread of the virus. This study aimed to evaluate the changes in di…
View article: Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study
Early signature in the blood lipidome associated with subsequent cognitive decline in the elderly: A case-control analysis nested within the Three-City cohort study Open
View article: Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells
Caffeine Compromises Proliferation of Human Hippocampal Progenitor Cells Open
The age-associated reduction in the proliferation of neural stem cells (NSCs) has been associated with cognitive decline. Numerous factors have been shown to modulate this process, including dietary components. Frequent consumption of caff…
View article: Improving the reporting quality of intervention trials addressing the inter-individual variability in response to the consumption of plant bioactives: quality index and recommendations
Improving the reporting quality of intervention trials addressing the inter-individual variability in response to the consumption of plant bioactives: quality index and recommendations Open
View article: Impact of Foods and Dietary Supplements Containing Hydroxycinnamic Acids on Cardiometabolic Biomarkers: A Systematic Review to Explore Inter-Individual Variability
Impact of Foods and Dietary Supplements Containing Hydroxycinnamic Acids on Cardiometabolic Biomarkers: A Systematic Review to Explore Inter-Individual Variability Open
Plant-based diets rich in bioactive compounds such as polyphenols have been shown to positively modulate the risk of cardiometabolic (CM) diseases. The inter-individual variability in the response to these bioactives may affect the finding…
View article: Diet‐Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort
Diet‐Related Metabolites Associated with Cognitive Decline Revealed by Untargeted Metabolomics in a Prospective Cohort Open
Scope Untargeted metabolomics may reveal preventive targets in cognitive aging, including within the food metabolome. Methods and results A case‐control study nested in the prospective Three‐City study includes participants aged ≥65 years …
View article: Biomarkers of food intake for cocoa and liquorice (products): a systematic review
Biomarkers of food intake for cocoa and liquorice (products): a systematic review Open
View article: Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota
Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota Open
Gut microbiota-related metabolites are potential clinical biomarkers for cardiovascular disease (CVD). Circulating succinate, a metabolite produced by both microbiota and the host, is increased in hypertension, ischemic heart disease, and …
View article: Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data Open
View article: Additional file 2: Table S2. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
Additional file 2: Table S2. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data Open
Enriched data and their main metabolite identifiers for ORA analysis. (XLSX 9ย�kb)
View article: Additional file 1: Table S1. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
Additional file 1: Table S1. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data Open
Full list of significant metabolites of the five datasets used in the present study (adjusted P-value
View article: Additional file 3: Table S3. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
Additional file 3: Table S3. of Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data Open
List of features of the tools analysed by multiple correspondence analysis. Abbreviations: N, no; Y, yes. (XLSX 12ย�kb)
View article: Microbial metabolites are associated with a high adherence to a Mediterranean dietary pattern using a 1H-NMR-based untargeted metabolomics approach
Microbial metabolites are associated with a high adherence to a Mediterranean dietary pattern using a 1H-NMR-based untargeted metabolomics approach Open
View article: “Cocoa and Chocolate: Science and Gastronomy”—The Second Annual Workshop of the Research Institute on Nutrition and Food Security (INSA): 9 November 2016
“Cocoa and Chocolate: Science and Gastronomy”—The Second Annual Workshop of the Research Institute on Nutrition and Food Security (INSA): 9 November 2016 Open
The Research Institute on Nutrition and Food Security at the University of Barcelona (INSA‐UB) was founded in 2005 by twenty‐two research groups from the Faculties of Pharmacy and Food Science; Biology; Chemistry; and Geography and History…
View article: Urinary <sup>1</sup>H Nuclear Magnetic Resonance Metabolomic Fingerprinting Reveals Biomarkers of Pulse Consumption Related to Energy-Metabolism Modulation in a Subcohort from the PREDIMED study
Urinary <sup>1</sup>H Nuclear Magnetic Resonance Metabolomic Fingerprinting Reveals Biomarkers of Pulse Consumption Related to Energy-Metabolism Modulation in a Subcohort from the PREDIMED study Open
Little is known about the metabolome fingerprint of pulse consumption. The study of robust and accurate biomarkers for pulse dietary assessment has great value for nutritional epidemiology regarding health benefits and their mechanisms. To…