Mireille Thomas
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View article: Dietary supplementation with nacre reduces cortical bone loss in aged female mice
Dietary supplementation with nacre reduces cortical bone loss in aged female mice Open
Aging is associated with detrimental bone loss leading to fragility fractures in both men and women. Notably, a majority of bone loss with aging is cortical, as well as a large number of fractures are non-vertebral and at the non-hip sites…
View article: COVID-19 Clusters in Belgian Nursing Homes: Impact of Facility Characteristics and Vaccination on Cluster Occurrence, Duration and Severity
COVID-19 Clusters in Belgian Nursing Homes: Impact of Facility Characteristics and Vaccination on Cluster Occurrence, Duration and Severity Open
COVID-19 severely affected nursing home residents from March 2020 onwards in Belgium. This study aimed to model the impact of vaccination and facility characteristics on cluster occurrence, duration and severity in this setting. Possible c…
View article: Deletion of osteopontin or bone sialoprotein induces opposite bone responses to mechanical stimulation in mice
Deletion of osteopontin or bone sialoprotein induces opposite bone responses to mechanical stimulation in mice Open
View article: Dual-functionalized titanium by ultrafast laser texturing to enhance human gingival fibroblasts adhesion and minimize Porphyromonas gingivalis colonization
Dual-functionalized titanium by ultrafast laser texturing to enhance human gingival fibroblasts adhesion and minimize Porphyromonas gingivalis colonization Open
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View article: Protective Effect on Bone of Nacre Supplementation in Ovariectomized Rats
Protective Effect on Bone of Nacre Supplementation in Ovariectomized Rats Open
Nacre has emerged as a beneficial natural product for bone cells and tissues, but its effect was only studied by gavage in the ovariectomized mouse model. We sought to assess the antiosteoporotic effect of nacre through a nutritional suppl…
View article: Nacre supplementation limits bone loss induced by ovariectomy in rats
Nacre supplementation limits bone loss induced by ovariectomy in rats Open
View article: Nacre supplement protects old mice from bone loss
Nacre supplement protects old mice from bone loss Open
View article: Hindlimb Unloading in C57bl/6j Mice Induces Bone Loss at Thermoneutrality Without Change in Osteocyte and Lacuno-Canalicular Network
Hindlimb Unloading in C57bl/6j Mice Induces Bone Loss at Thermoneutrality Without Change in Osteocyte and Lacuno-Canalicular Network Open
View article: YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response
YAP/TAZ: Key Players for Rheumatoid Arthritis Severity by Driving Fibroblast Like Synoviocytes Phenotype and Fibro-Inflammatory Response Open
Objective The role of YAP/TAZ, two transcriptional co-activators involved in several cancers, was investigated in rheumatoid arthritis (RA). Methods Fibroblast like synoviocytes (FLS) from patients with RA or osteoarthritis were cultured i…
View article: Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model
Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model Open
Sjögren’s syndrome (SjS) is a frequent systemic autoimmune disease responsible for a major decrease in patients’ quality of life, potentially leading to life-threatening conditions while facing an unmet therapeutic need. Hence, we assessed…
View article: Knockout of osteopontin or bone sialoprotein induces opposite response to mechanical stimulation
Knockout of osteopontin or bone sialoprotein induces opposite response to mechanical stimulation Open
View article: Feeding powdered nacre prevents ovariectomy-induced bone loss in the rat
Feeding powdered nacre prevents ovariectomy-induced bone loss in the rat Open
View article: Parathyroid Hormone Remodels Bone Transitional Vessels and the Leptin Receptor-Positive Pericyte Network in Mice
Parathyroid Hormone Remodels Bone Transitional Vessels and the Leptin Receptor-Positive Pericyte Network in Mice Open
Intermittent parathyroid hormone (iPTH) is anti-osteoporotic and affects bone vessels. Transitional capillaries close to the bone surface, which express both endomucin (Edm) and CD31, bear leptin receptor-expressing (LepR) perivascular cel…
View article: Deletion of OPN in BSP knockout mice does not correct bone hypomineralization but results in high bone turnover
Deletion of OPN in BSP knockout mice does not correct bone hypomineralization but results in high bone turnover Open
View article: Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model
Early sclerostin expression explains bone formation inhibition before arthritis onset in the rat adjuvant-induced arthritis model Open
Periarticular bone loss in rheumatoid arthritis (RA) is considered to be mainly related to synovial inflammation. However, strong bone loss has also described at the time of arthritis onset. Recently, a paradoxical exacerbation of joint da…
View article: Effects of short-term dry immersion on bone remodeling markers, insulin and adipokines
Effects of short-term dry immersion on bone remodeling markers, insulin and adipokines Open
Our results demonstrated that DI induced an unbalanced remodeling activity and the onset of insulin resistance. This metabolic adaptation was concomitant with higher levels of Glu-OC. This finding confirms the role of bone as an endocrine …
View article: The Impairment of Osteogenesis in Bone Sialoprotein (BSP) Knockout Calvaria Cell Cultures Is Cell Density Dependent
The Impairment of Osteogenesis in Bone Sialoprotein (BSP) Knockout Calvaria Cell Cultures Is Cell Density Dependent Open
Bone sialoprotein (BSP) belongs to the "small integrin-binding ligand N-linked glycoprotein" (SIBLING) family, whose members interact with bone cells and bone mineral. BSP is strongly expressed in bone and we previously showed that BSP kno…