Mirfin Mpundu
YOU?
Author Swipe
View article: Facing up to reality: over-the-counter access to antibiotics in low-income and middle-income countries needs a paradigm shift in thinking
Facing up to reality: over-the-counter access to antibiotics in low-income and middle-income countries needs a paradigm shift in thinking Open
Almost half of the global population do not have access to universal health coverage and the current shortfall of health-care professionals (including doctors and nurses) is estimated to reach a deficit of 11 million by 2030, disproportion…
View article: Systems Policy Analysis for Antimicrobial Resistance Targeted Action (SPAARTA): A Research Protocol
Systems Policy Analysis for Antimicrobial Resistance Targeted Action (SPAARTA): A Research Protocol Open
Background The majority of countries (88%) have an Antimicrobial Resistance (AMR) National Action Plan (NAP V.1.0), but many remain unimplemented, and lack funding for interventions. Intervention selection requires a systematic approach to…
View article: Economic costing methodologies for drug-resistant bacterial infections in humans in low-and middle-income countries: a systematic review
Economic costing methodologies for drug-resistant bacterial infections in humans in low-and middle-income countries: a systematic review Open
Overall, the use of descriptive statistics without justification, limited consideration for potential data challenges, including confounders, and short-term horizons suggest that the full AMR cost burden in humans in LMICs has not been wel…
View article: Current status and future direction of antimicrobial stewardship programs and antibiotic prescribing in primary care hospitals in Zambia
Current status and future direction of antimicrobial stewardship programs and antibiotic prescribing in primary care hospitals in Zambia Open
Background Antimicrobial Stewardship Programs (ASPs) intended to optimize antibiotic use will be more effective if informed by the current status and patterns of antibiotic utilisation. In Zambia's primary healthcare (PHC) settings, data o…
View article: Antibiotic resistance profiles in Gram-negative bacteria causing bloodstream and urinary tract infections in paediatric and adult patients in Ndola District, Zambia, 2020–2021
Antibiotic resistance profiles in Gram-negative bacteria causing bloodstream and urinary tract infections in paediatric and adult patients in Ndola District, Zambia, 2020–2021 Open
High level antibiotic resistance was observed in GNB known to be prevalent causative agents of BSIs and UTIs locally in Zambia. Improving microbiology diagnostic capacity, strengthening antimicrobial stewardship programs and enforcing infe…
View article: Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium
Insights of SEDRIC, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium Open
The increasing threat from infection with drug-resistant pathogens is among the most serious public health challenges of our time. Formed by Wellcome in 2018, the Surveillance and Epidemiology of Drug-Resistant Infections Consortium (SEDRI…
View article: Systems Policy Analysis for Antimicrobial Resistance Targeted Action (SPAARTA): A Research Protocol
Systems Policy Analysis for Antimicrobial Resistance Targeted Action (SPAARTA): A Research Protocol Open
Background The majority of countries (64%) have an Antimicrobial Resistance (AMR) National Action Plan (NAP V.1.0), but many remain unimplemented, and lack funding for interventions. Intervention selection requires a systematic approach to…
View article: Antimicrobial stewardship situation analysis in selected hospitals in Zambia: findings and implications from a national survey
Antimicrobial stewardship situation analysis in selected hospitals in Zambia: findings and implications from a national survey Open
Background Antimicrobial stewardship (AMS) programs are critical in combating antimicrobial resistance (AMR). In Zambia, there is little information regarding the capacity of hospitals to establish and implement AMS programs. The objective…
View article: Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey
Antibiotic use and adherence to the WHO AWaRe guidelines across 16 hospitals in Zambia: a point prevalence survey Open
Background The inappropriate use of antibiotics in hospitals contributes to the development and spread of antimicrobial resistance (AMR). This study evaluated the prevalence of antibiotic use and adherence to the World Health Organization …
View article: ECONOMIC COSTING METHODOLOGIES OF DRUG RESISTANT BACTERIA INFECTIONS IN LOW-AND MIDDLE-INCOME COUNTRIES: A SYSTEMATIC REVIEW
ECONOMIC COSTING METHODOLOGIES OF DRUG RESISTANT BACTERIA INFECTIONS IN LOW-AND MIDDLE-INCOME COUNTRIES: A SYSTEMATIC REVIEW Open
eview question / Objective i.To asses the justification of using particular AMR infections costing methodologies.ii.To analyse the relevant cost variables for economic costing of AMR infections with regard to patient, provider, and societa…
View article: Knowledge, awareness and practices of healthcare workers regarding antimicrobial use, resistance and stewardship in Zambia: a multi-facility cross-sectional study
Knowledge, awareness and practices of healthcare workers regarding antimicrobial use, resistance and stewardship in Zambia: a multi-facility cross-sectional study Open
Background Antimicrobial resistance (AMR) poses a threat to public health globally. Despite its consequences, there is little information about the knowledge, awareness, and practices towards AMR among healthcare workers (HCWs). Therefore,…
View article: Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance
Antimicrobial resistance and the great divide: inequity in priorities and agendas between the Global North and the Global South threatens global mitigation of antimicrobial resistance Open
To limit the catastrophic effects of the increasing bacterial resistance to antimicrobials on health, food, environmental, and geopolitical security, and ensure that no country or region is left behind, a coordinated global approach is req…
View article: Mitigating antimicrobial resistance (AMR) using implementation research: a development funder’s approach
Mitigating antimicrobial resistance (AMR) using implementation research: a development funder’s approach Open
Despite the escalating burden of antimicrobial resistance (AMR), the global response has not sufficiently matched the scale and scope of the issue, especially in low- and middle-income countries (LMICs). While many countries have adopted n…
View article: An analysis of existing national action plans for antimicrobial resistance—gaps and opportunities in strategies optimising antibiotic use in human populations
An analysis of existing national action plans for antimicrobial resistance—gaps and opportunities in strategies optimising antibiotic use in human populations Open
At the 2015 World Health Assembly, UN member states adopted a resolution that committed to the development of national action plans (NAPs) for antimicrobial resistance (AMR). The political determination to commit to NAPs and the availabili…
View article: Phenotypic and genotypic antibiotic susceptibility profiles of Gram-negative bacteria isolated from bloodstream infections at a referral hospital, Lusaka, Zambia
Phenotypic and genotypic antibiotic susceptibility profiles of Gram-negative bacteria isolated from bloodstream infections at a referral hospital, Lusaka, Zambia Open
Bloodstream infections (BSI) caused by antimicrobial-resistant (AMR) Gram-negative bacteria (GNB) are a significant cause of morbidity and mortality. Third-generation cephalosporins (3GCs) have been used as empiric treatment for BSI and ot…
View article: Introducing the global antimicrobial stewardship partnership hub (GASPH): creating conditions for successful global partnership collaboration
Introducing the global antimicrobial stewardship partnership hub (GASPH): creating conditions for successful global partnership collaboration Open
In 2015, 196 countries formally committed to a Global Action Plan to address antimicrobial resistance (AMR). However, translating policy into practice is not happening at pace and the recent Global Research on AntiMicrobial resistance (GRA…
View article: National action plan on antimicrobial resistance: An evaluation of implementation in the World Health Organization Africa region
National action plan on antimicrobial resistance: An evaluation of implementation in the World Health Organization Africa region Open
In line with global instruments, within the last five years, two-thirds of all countries in the WHO Africa Region (WHO AFR) have developed a National Action Plan (NAP) on Antimicrobial Resistance (AMR). We sought to evaluate progress made …
View article: Antibiotic resistance: calling time on the ‘silent pandemic’
Antibiotic resistance: calling time on the ‘silent pandemic’ Open
It is time to stop referring to the antibiotic resistance pandemic as ‘silent’. Continuing to use such a term denies the reality that antibiotic-resistant bacterial infections, driven by misuse and abuse of antibiotics by humans against mi…
View article: <b>Equitable Access to Antibiotics:</b> A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response
<b>Equitable Access to Antibiotics:</b> A Core Element and Shared Global Responsibility for Pandemic Preparedness and Response Open
Securing equitable antibiotic access as an essential component for health system resilience and pandemic preparedness requires a systems perspective. This article discusses key components that need to be coordinated and paired with adequat…
View article: Navigating sociocultural disparities in relation to infection and antibiotic resistance—the need for an intersectional approach
Navigating sociocultural disparities in relation to infection and antibiotic resistance—the need for an intersectional approach Open
One of the key drivers of antibiotic resistance (ABR) and drug-resistant bacterial infections is the misuse and overuse of antibiotics in human populations. Infection management and antibiotic decision-making are multifactorial, complex pr…
View article: Health Systems Predictors and Trends of Access to Vaccinations in 9 sub-Saharan African Countries
Health Systems Predictors and Trends of Access to Vaccinations in 9 sub-Saharan African Countries Open
The purpose of this ecological quantitative study was to examine the predictors of health systems building blocks and their interactions in improving access and uptake of immunizations in nine sub-Saharan African countries. Immunization ra…
View article: A Global Antimicrobial Conservation Fund for Low- and Middle-Income Countries
A Global Antimicrobial Conservation Fund for Low- and Middle-Income Countries Open
On 21st September 2016, for only the 4th time in history, a health topic will take centre stage at a United Nations General Assembly (UNGA) high-level meeting where heads of state are present. A day-long session has been convened to discus…