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View article: The <scp>NIMH</scp> supports more comprehensive and inclusive genomic studies in psychiatry
The <span>NIMH</span> supports more comprehensive and inclusive genomic studies in psychiatry Open
The inclusion of diverse populations in genomic studies is key to generate more comprehensive findings, as well as to ensure equitable research. However, most genomic studies have been conducted as yet on cohorts of European ancestry, with…
View article: From genetics to biology: advancing mental health research in the Genomics ERA
From genetics to biology: advancing mental health research in the Genomics ERA Open
The Genomics Workgroup of the National Advisory Mental Health Council (NAMHC) recently issued a set of recommendations for advancing the NIMH psychiatric genetics research program and prioritizing subsequent follow-up studies. The report e…
View article: Making Sense of Epigenetics
Making Sense of Epigenetics Open
The gene-environment interactions that underlie development and progression of psychiatric illness are poorly understood. Despite a century of progress, genetic approaches have failed to identify new treatment modalities, perhaps because o…
View article: Association of Superoxide Dismutase 2 (<i>SOD2</i>) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel
Association of Superoxide Dismutase 2 (<i>SOD2</i>) Genotype with Gray Matter Volume Shrinkage in Chronic Alcohol Users: Replication and Further Evaluation of an Addiction Gene Panel Open
Converging independent evidence for a SOD2 gene association with gray matter volume shrinkage in chronic alcohol users suggests that SOD2 genetic variants predict differential brain volume loss mediated by free radicals. This study also pr…