Miriam Bennett
YOU?
Author Swipe
View article: Rapid Access Diagnostics for Asthma (RADicA): protocol for a prospective cohort study to determine the optimum series of investigations to diagnose asthma using conventional and novel tests
Rapid Access Diagnostics for Asthma (RADicA): protocol for a prospective cohort study to determine the optimum series of investigations to diagnose asthma using conventional and novel tests Open
Introduction The diagnosis of asthma is often based on characteristic patterns of symptoms in the absence of an alternative explanation, resulting in over and under diagnosis. Therefore, diagnostic guidelines usually recommend including co…
View article: Re-imagining women’s leadership in the third-space
Re-imagining women’s leadership in the third-space Open
The role of the third space woman leader is a blurry one (Denney, 2021). While making a difference for students is at the heart of our work, creating and leading teams in a direction often not of our choosing and from a position that cross…
View article: Performance characteristics of basophil activations tests for diagnosing penicillin allergy: a meta-analysis
Performance characteristics of basophil activations tests for diagnosing penicillin allergy: a meta-analysis Open
Background: Approximately 10% of the global population identify themselves as penicillin allergic, yet 90% are not truly allergic and could safely tolerate penicillin. There is no simple way to identify these people. Current in vitro diagn…
View article: S42 Diagnosing asthma in children – how can it be improved?
S42 Diagnosing asthma in children – how can it be improved? Open
Introduction National Institute for Health and Care Excellence (NICE) guideline (NG80) aims to aid asthma diagnosis in children and suggests sequential lung function testing. We compared diagnostic outcomes using NG80 to that of an 'expert…
View article: Amoxicillin induced mast cell degranulation mediated by FcεRI specific IgG: a new insight to beta-lactam allergy
Amoxicillin induced mast cell degranulation mediated by FcεRI specific IgG: a new insight to beta-lactam allergy Open
Amoxicillin induced mast cell degranulation mediated by FcεRI specific IgG: a new insight to beta-lactam allergy To the editor,Immediate drug hypersensitivity reactions (IDHR) to beta-lactams (BL), referred to here as beta-lactam allergy (…
View article: Towards a safe and efficient de‐labelling penicillin allergy service by non‐allergists
Towards a safe and efficient de‐labelling penicillin allergy service by non‐allergists Open
To the Editor, We read with great interest the ‘BSACI guideline for the set-up of penicillin allergy de-labelling services by non-allergists working in a hospital setting’ by Savic et al.1 which provides guidance on evaluation and testing …
View article: Progenitor cell‐derived basophils: A novel barcoded passive degranulation assay in allergic diseases
Progenitor cell‐derived basophils: A novel barcoded passive degranulation assay in allergic diseases Open
Background Effector cells assays provide an overall measure of responsiveness to allergen, but the lack of reliable and high‐throughput assays limits the clinical utility. We aimed to develop a high‐throughput basophil activation test base…
View article: Defining the normal range of fractional exhaled nitric oxide in children: one size does not fit all
Defining the normal range of fractional exhaled nitric oxide in children: one size does not fit all Open
Background The normal range of fractional exhaled nitric oxide ( F ENO ) is influenced by demographic factors. However, single, fixed cut-off values are used for clinical interpretation in children despite rapid growth. We aimed to define …
View article: Large scale clinical trials: lessons from the COVID-19 pandemic
Large scale clinical trials: lessons from the COVID-19 pandemic Open
Background The COVID-19 pandemic has presented substantial new challenges to clinical and research teams. Our objective was to analyse the experience of investigators and research delivery staff regarding the research response to COVID-19 …
View article: A Case of Life-Threatening Airway Obstruction Caused by Acute Diphtheria Infection in the United Kingdom
A Case of Life-Threatening Airway Obstruction Caused by Acute Diphtheria Infection in the United Kingdom Open
Diphtheria is a highly contagious and potentially life-threatening infection. Cases in the United Kingdom are rare due to widespread vaccination. However, in recent years, there has been a notable increase in cases in the United Kingdom. W…
View article: Effect of Acute Stress Glycemic Control and Long-Term Glycemic Control on the Incidence of Post-Operative Infection in Diabetics Undergoing Cardiac Surgery
Effect of Acute Stress Glycemic Control and Long-Term Glycemic Control on the Incidence of Post-Operative Infection in Diabetics Undergoing Cardiac Surgery Open
Objective Post-operative infection after cardiac surgery causes prolonged hospital stay and increased mortality. In patients with diabetes, peri-operative and pre-operative glycemic control have been associated with increased risk of post-…
View article: The safety of cardioselective β<sub>1</sub>-blockers in asthma: literature review and search of global pharmacovigilance safety reports
The safety of cardioselective β<sub>1</sub>-blockers in asthma: literature review and search of global pharmacovigilance safety reports Open
Introduction Beta-blockers are key in the management of cardiovascular diseases but blocking airway β 2 -receptors can cause severe and sometimes fatal bronchoconstriction in people with asthma. Although cardioselective β 1 -blockers may b…
View article: Cerebral oximetry in adult cardiac surgery to reduce the incidence of neurological impairment and hospital length-of-stay: A prospective, randomized, controlled trial
Cerebral oximetry in adult cardiac surgery to reduce the incidence of neurological impairment and hospital length-of-stay: A prospective, randomized, controlled trial Open
Background Cerebral oximetry using near-infrared spectroscopy (NIRS) has been shown to reduce neurological dysfunction and hospital length-of-stay after adult cardiac surgery in some but not all studies. We audited maintaining cerebral sat…
View article: Progenitor cell-derived basophils: a novel barcoded passive degranulation assay in allergy diagnosis
Progenitor cell-derived basophils: a novel barcoded passive degranulation assay in allergy diagnosis Open
Background: Effector cells assays provide an overall measure of responsiveness to allergen, but the lack of reliable, high-throughput assays limits the clinical utility of this approach. The aim of this study was to develop a high-throughp…
View article: AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation
AlphaE Integrin Expression Is Increased in the Ileum Relative to the Colon and Unaffected by Inflammation Open
αE+ cells, which have been shown to have inflammatory potential, are increased in the ileum in comparison with the colon in both Crohn's disease and ulcerative colitis, as well as in healthy subjects. In inflammatory bowel disease patients…