Explanipedia

Appendiceal duplication leading to recurrent ileocolonic intussusception: A case report Open

E Arnold, Miriam Conces, Raul E. Sanchez, Sara A. Mansfield, Jennifer H. Aldrink · 2025

Breaking the Mold! A Rare Lung Neoplasm in Childhood Open

Eric S. Mull, Raffaele De Gaudio, Nicoleta C. Arva, Miriam Conces, Nathan Fagan · 2025

Virilization and Hyperandrogenism in Turner Syndrome without Y Mosaicism: A Case Report and Review of the Literature Open

Jacquelyn Evans, Jennifer M. Ladd, Miriam Conces, Scott E. Hickey, Daniel C. Koboldt , et al. · 2025

OHC hyperplasia is a rare but important diagnosis to consider. Laparoscopic bilateral gonadectomy is both diagnostic and therapeutic and should be considered a first-line treatment for patients with POI and virilization in the absence of o…

36O First-in-human phase I study of a dual-conditionally active biologic (CAB) EpCAM x CD3 bispecific T-cell engager (TCE), BA3182, in patients with treatment refractory metastatic adenocarcinoma Open

Jennifer B. Goldstein, James Thomas, J.E.E. Selfridge, Miriam Conces, D. Mahalingam , et al. · 2025

486P Preliminary results from a first-in-human phase I study of a dual-conditionally binding EpCAM x CD3 bispecific T-cell engager, BA3182, in pts with treatment refractory metastatic adenocarcinoma Open

A. Starodub, James Thomas, J.E.E. Selfridge, Miriam Conces, D. Mahalingam , et al. · 2025

Treatment, toxicity, and mortality after subsequent breast cancer in female survivors of childhood cancer Open

Cindy Im, Hasibul Hasan, Emily Stene, Sarah Monick, Ryan K. Rader , et al. · 2025

Peripheral nerve sheath tumors in the head and neck in patients with APC gene deletion mutations: a case report and scoping review of the literature Open

Koral Blunt, Monirah Albathi, Miriam Conces, Tendy Chiang · 2025

Adenomatous polyposis coli (APC) is a tumor suppressor gene expressed throughout the body. APC mutations increase the risk of malignancy and are often characterized by syndromes that encompass a spectrum of neoplastic manifestations, such …

Late subsequent leukemia after childhood cancer: A report from the Childhood Cancer Survivor Study (CCSS) Open

Taumoha Ghosh, Geehong Hyun, Rikeenkumar Dhaduk, Miriam Conces, Michael Arnold , et al. · 2024

Background Subsequent short‐latency leukemias are well‐described among survivors of childhood cancer. However, late (5–14.9 years from diagnosis, LL) and very late (≥15 years from diagnosis, VLL) subsequent leukemias have not been well stu…

Molecular testing for gastrointestinal pathogens in intestinal tissue of infants with necrotizing enterocolitis or spontaneous intestinal perforation Open

Maria M. Talavera‐Barber, Pablo J. Sánchez, Miriam Conces, Irina Kaptsan, Kathy Everhart , et al. · 2024

Objective The objective of this study was to determine the frequency of common gastrointestinal bacterial, parasitic, and viral pathogen detection in necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) -associated i…

Superior performance of biofilm versus planktonic Limosilactobacillus reuteri in protection of the intestines and brain in a piglet model of necrotizing enterocolitis Open

Samantha J. Wala, Nitin Sajankila, Mecklin V. Ragan, Audrey F. Duff, Joseph Wickham , et al. · 2023

Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal-related death in premature infants. Its etiology is multifactorial, with intestinal dysbiosis playing a major role. Probiotics are a logical preventative therapy for …

Molecular Testing for Gastrointestinal Pathogens in Intestinal Tissue of Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation Open

Maria M. Talavera‐Barber, Pablo J. Sánchez, Miriam Conces, Irina Kaptsan, Kathy Everhart , et al. · 2023

Objective The objective of this study was to determine the frequency of common gastrointestinal bacterial, parasitic, and viral pathogens in necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) -associated intestinal…

Subsequent female breast cancer risk associated with anthracycline chemotherapy for childhood cancer Open

Yuehan Wang, Cécile M. Ronckers, Flora E. van Leeuwen, Chaya S. Moskowitz, Wendy M. Leisenring , et al. · 2023

OUTC-04. SUBSEQUENT CNS MALIGNANCY AMONG SURVIVORS OF CHILDHOOD CANCER: A REPORT FROM THE CHILDHOOD CANCER SURVIVOR STUDY (CCSS) Open

Robert Galvin, Yan Chen, Yan Yuan, Tabitha Cooney, Rebecca M. Howell , et al. · 2023

Subsequent malignant neoplasms (SMNs) of the central nervous system (CNS) following childhood cancer are a frequently fatal late effect of cancer therapy. We used the CCSS (5-year childhood cancer survivors, diagnosed 1970-1999) to assess …

Development of a novel definitive scoring system for an enteral feed-only model of necrotizing enterocolitis in piglets Open

Mecklin V. Ragan, Samantha J. Wala, Nitin Sajankila, Audrey F. Duff, Yijie Wang , et al. · 2023

Introduction Necrotizing enterocolitis (NEC) is a complex inflammatory disorder of the human intestine that most often occurs in premature newborns. Animal models of NEC typically use mice or rats; however, pigs have emerged as a viable al…

Presentation and evaluation of an atypical, supraclavicular mass in a pediatric patient Open

Austin Schafer, David Z. Allen, Weston L. Niermeyer, Charles Elmaraghy, Miriam Conces · 2022

Although the vast majority of pediatric neck masses are benign, pediatric malignancies commonly present in the supraclavicular region. We present the case of a 4-year-old male who presented with a mass in the trapezius muscle with accompan…

Expanding the Clinical Phenotype of FGFR1 Internal Tandem Duplication Open

Esko A. Kautto, Kathleen M. Schieffer, Sean McGrath, Anthony R. Miller, Maria Elena Hernandez Gonzalez , et al. · 2022

Closed spinal dysraphism (SD) is a type of neural tube defect originating during early embryonic development whereby the neural tissue of the spinal defect remains covered by skin, often coinciding with markers of cutaneous stigmata. It is…

Subsequent malignant neoplasms in the Childhood Cancer Survivor Study: Occurrence of cancer types in which human papillomavirus is an established etiologic risk factor Open

Tara O. Henderson, Brynn Fowler, Haley A. Hamann, Paul C. Nathan, Jillian Whitton , et al. · 2021

Background Human papillomavirus (HPV)‐associated subsequent malignant neoplasms (SMN HPV ) in childhood cancer survivors are poorly understood. Methods The cumulative risk of SMN HPV was assessed among 24,363 Childhood Cancer Survivor Stud…

MYOD1 as a prognostic indicator in rhabdomyosarcoma Open

Atif Ahmed, Sultan S. Habeebu, Midhat S. Farooqi, Alan S. Gamis, Elizabeth M. Gonzalez , et al. · 2021

Background/objectives Rhabdomyosarcoma (RMS) is characterized by the expression of the myogenic regulatory protein MYOD1. Histologic types include alveolar, embryonal (ERMS), and spindle cell sclerosing RMS (SRMS). SRMS harbors MYOD1 mutat…

A novel probiotic therapeutic in a murine model of Clostridioides difficile colitis Open

R Dennis Shelby, Grace E. Janzow, Lauren Mashburn‐Warren, Jeffrey D. Galley, Natalie Tengberg , et al. · 2020

A single dose of Lactobacillus reuteri in its biofilm state reduces the severity and incidence of experimental C. difficile infection when administered as both prophylactic and treatment therapy.

Abstracts from USCAP 2020: Pediatric and Perinatal Pathology (1842-1868) Open

Jason L. Hornick, Rhonda K. Yantiss, Laura W. Lamps, Cme Subcommittee, Steven D. Billings , et al. · 2020

Abstracts from USCAP 2020: Pediatric and Perinatal Pathology (1842-1868) Open

Jason L. Hornick, Rhonda K. Yantiss, Laura W. Lamps, Cme Subcommittee, Steven D. Billings , et al. · 2020

Cytoplasmic Fibrillar Aggregates in Gallbladder Epithelium Are a Frequent Mimic of Cystoisospora in Pediatric Cholecystectomy Specimens Open

Gary S. Rose, Christina A. Arnold, Kamran Badizadegan, Christopher M. Carter, Miriam Conces , et al. · 2019

Context.— Cystoisospora belli is an intracellular parasite associated with gastrointestinal disease in immunocompromised hosts. Although infection has been classically associated with intestinal disease, studies have identified Cystoisospo…

Acute Myeloid Leukemia with RAM Immunophenotype: A Pediatric Case with Unusual Morphologic Features Open

Miriam Conces, Rolla Abu‐Arja, Suzanne Reed, Hemalatha G. Rangarajan, Terri Guinipero , et al. · 2017

The RAM immunophenotype has been recently described as a subtype of acute myelogenous leukemia (AML) that is characterized clinically by extremely poor prognosis. We present a case of AML with RAM immunophenotype in a 5-year-old patient th…

Adenovirus and “Culture-Negative Sepsis” in a Preterm Neonate Open

Eunkyung Song, Preeti Jaggi, Miriam Conces, Adriana E. Kajon, Pablo J. Sánchez , et al. · 2016

Background Respiratory viral infections remain an underrecognized cause of morbidity and mortality among preterm infants in the neonatal intensive care unit (NICU). Case Report An eight day old, 650 gram birth weight, 23 week…

A Strategy forHelicobacterImmunohistochemistry Utilization in Pediatric Practice Open

Miriam Conces, Christina A. Arnold, Peter B. Baker, Christopher M. Carter, Bonita Fung , et al. · 2016

We recommend performing Helicobacter IHC on pediatric gastric biopsy specimens with any of the above inflammatory patterns. This approach can sensitively identify pediatric patients with Helicobacter gastritis, limit IHC staining to approx…

Histopathologic identification and pattern recognition of common viral infections in the general pathology practice: An illustrated review Open

Flora Yazigi, Basil M. Kahwash, Fahd Al Sufiani, Miriam Conces, Vinay Prasad , et al. · 2016

Pattern recognition and cytologic features remain essential diagnostic tools in pathology. Viral cytopathic effect may be the first clue to a diagnosis of a viral infection. This paper aims to provide a brief illustrated summary of the his…

Jacobsen/Paris-Trousseau Syndrome: Report of a Case with Emphasis on Platelet’s Light Microscopic and Ultrastructure Findings Open

Michael Losos, Basil M. Kahwash, Miriam Conces, Joel Thompson, Riten Kumar , et al. · 2016

Jacobsen syndrome (JS) is a rare, inherited disorder, characterized by facial and skull dysmorphism, mental retardation, and platelet abnormalities. Paris-Trousseau syndrome (PTS) is a platelet function disorder that may be encountered in …

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