Miriam Wiestler
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View article: Chronic Imbalance? Gender Disparities in Gastroenterology Across a Decade of the Visceral Medicine Congress in Germany
Chronic Imbalance? Gender Disparities in Gastroenterology Across a Decade of the Visceral Medicine Congress in Germany Open
Despite efforts toward gender equality, disparities persist in medical careers and leadership. This study examines gender representation in gastroenterology at the German Visceral Medicine Congress from 2013 to 2024, focusing on changes ov…
View article: Long-Term Clinical and Endoscopic Outcomes of Crohn’s Disease Following Liver Transplantation: A Multicenter Cohort Study
Long-Term Clinical and Endoscopic Outcomes of Crohn’s Disease Following Liver Transplantation: A Multicenter Cohort Study Open
Patients with Crohn’s disease (CD) may require liver transplantation (LT) due to advanced liver diseases, including primary sclerosing cholangitis (PSC), autoimmune hepatitis, or other etiologies. However, data on CD activity and the use o…
View article: Assessing Highly Processed Food Consumption in Patients with Inflammatory Bowel Disease: Application of the German Screening Questionnaire (sQ-HPF)
Assessing Highly Processed Food Consumption in Patients with Inflammatory Bowel Disease: Application of the German Screening Questionnaire (sQ-HPF) Open
Background/Objectives: The consumption of highly processed foods (HPFs) is increasing on a global scale, and these foods have been associated with non-communicable diseases (NCDs). In particular, the consumption of HPFs has been associated…
View article: Sex Disparities in Treatment Trajectories of Inflammatory Bowel Disease Are Associated With Diagnostic Delay
Sex Disparities in Treatment Trajectories of Inflammatory Bowel Disease Are Associated With Diagnostic Delay Open
Background Diagnostic delay (DD) is a common finding in inflammatory bowel diseases (IBD). The reasons and effects of this delay are frequently underestimated, particularly in the context of sex. Our aims were to examine the impact of dela…
View article: Mucosal deficiency of mitochondria-driven humoral immunity is linked to Crohn’s Disease
Mucosal deficiency of mitochondria-driven humoral immunity is linked to Crohn’s Disease Open
Secretory IgA (SIgA) is critical for maintaining the intestinal barrier. A dysregulated B-cell compartment and altered Ig secretion have been well documented in Crohn’s disease (CD) patients, although their origin is unknown. To unravel th…
View article: Food-related Quality of Life in patients with Inflammatory Bowel Disease: Translation and Validation of the German version of FR-QoL-29
Food-related Quality of Life in patients with Inflammatory Bowel Disease: Translation and Validation of the German version of FR-QoL-29 Open
The psychosocial effects of eating and drinking – summarized as food-related quality of life (FR-QoL) – are underexplored in inflammatory bowel disease (IBD). Currently, there is no German instrument to assess FR-QoL in IBD patients. This …
View article: Sex Differences Outweigh Dietary Factors in Food-Related Quality of Life in Patients with Inflammatory Bowel Disease
Sex Differences Outweigh Dietary Factors in Food-Related Quality of Life in Patients with Inflammatory Bowel Disease Open
Background: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), consists of chronic gastrointestinal inflammation, with nutrition playing a significant role in its development. IBD patients often f…
View article: Disease-modifying strategies: Targeting protein kinases in multiple sclerosis and other autoimmune disorders
Disease-modifying strategies: Targeting protein kinases in multiple sclerosis and other autoimmune disorders Open
A wide variety of immunomodulatory therapies are already available for the treatment of multiple sclerosis (MS). Through fundamental insights from basic research with a gain of knowledge in the pathological processes underlying MS, the exp…
View article: Exploring Dietary- and Disease-Related Influences on Flatulence and Fecal Odor Perception in Inflammatory Bowel Disease
Exploring Dietary- and Disease-Related Influences on Flatulence and Fecal Odor Perception in Inflammatory Bowel Disease Open
Background/Objectives: Inflammatory bowel disease (IBD) affects gastrointestinal function and may alter fecal and flatulence odor (intestinal odor) due to changes in inflammation, the gut microbiome, and metabolism. Investigating the relat…
View article: Exploring Physical Activity, Sleep, and Nutrition’s Role in Fatigue Among Post-COVID-19 Patients
Exploring Physical Activity, Sleep, and Nutrition’s Role in Fatigue Among Post-COVID-19 Patients Open
Background/Objectives: A significant number of patients experience prolonged symptoms following COVID-19 in particular cases of fatigue. Yet, pathomechanisms of COVID-19-related fatigue remain unclear. Methods: This study investigated pati…
View article: Patients with Inflammatory Bowel Disease Show Fewer Sex-Related Differences in Their Dietary Behavior Than the General Population: A Qualitative Analysis
Patients with Inflammatory Bowel Disease Show Fewer Sex-Related Differences in Their Dietary Behavior Than the General Population: A Qualitative Analysis Open
Background: Since diet is generally recognized as an important factor directly modulating the gut microbiome, it is also considered a potential environmental triggering factor for the pathogenesis and onset of inflammatory bowel disease (I…
View article: P284 Sex-specific aspects in IBD: a multidimensional view
P284 Sex-specific aspects in IBD: a multidimensional view Open
Background Inflammatory bowel diseases (IBD), including Ulcerative colitis (UC) and Crohn's disease (CD), are chronic intestinal disorders characterised by varied intestinal symptoms and a negative impact on the patients` quality of life. …
View article: Treatment of autoimmunity: The impact of disease-modifying therapies in multiple sclerosis and comorbid autoimmune disorders
Treatment of autoimmunity: The impact of disease-modifying therapies in multiple sclerosis and comorbid autoimmune disorders Open
More than 10 disease-modifying therapies (DMT) are approved by the European Medicines Agency (EMA) and the US Food and Drug Administration (FDA) for the treatment of multiple sclerosis (MS) and new therapeutic options are on the horizon. D…
View article: P545 Does gender matter? Gender-related nutritional behaviour, disease activity and quality of life in patients with inflammatory bowel diseases
P545 Does gender matter? Gender-related nutritional behaviour, disease activity and quality of life in patients with inflammatory bowel diseases Open
Background The latest research clearly indicates that diet plays an important role in the onset and course of inflammatory bowel diseases (IBD). But especially data on gender specific aspects of diet in IBD patients are still lacking even …
View article: Impact on follow‐up strategies in patients with primary sclerosing cholangitis
Impact on follow‐up strategies in patients with primary sclerosing cholangitis Open
Background & Aims Evidence for the benefit of scheduled imaging for early detection of hepatobiliary malignancies in primary sclerosing cholangitis (PSC) is limited. We aimed to compare different follow‐up strategies in PSC with the hypoth…
View article: An Unusual Cause of Erythema on Both Lower Legs in a Patient With Crohn’s Disease
An Unusual Cause of Erythema on Both Lower Legs in a Patient With Crohn’s Disease Open
View article: Identification of Novel Population-Specific Cell Subsets in Chinese Ulcerative Colitis Patients Using Single-Cell RNA Sequencing
Identification of Novel Population-Specific Cell Subsets in Chinese Ulcerative Colitis Patients Using Single-Cell RNA Sequencing Open
View article: Risks and benefits of percutaneous transhepatic cholangiodrainage in patients with primary sclerosing cholangitis
Risks and benefits of percutaneous transhepatic cholangiodrainage in patients with primary sclerosing cholangitis Open
View article: Quality of Life Is Associated With Wearable-Based Physical Activity in Patients With Inflammatory Bowel Disease: A Prospective, Observational Study
Quality of Life Is Associated With Wearable-Based Physical Activity in Patients With Inflammatory Bowel Disease: A Prospective, Observational Study Open
OBJECTIVES: Patient-reported outcomes such as quality of life are gaining importance in the assessment of patients suffering from inflammatory bowel disease (IBD). The association of objectively measured physical activity and quality of li…
View article: P456 Quality of life is associated with wearable-based physical activity in patients with inflammatory bowel disease: a prospective, observational study
P456 Quality of life is associated with wearable-based physical activity in patients with inflammatory bowel disease: a prospective, observational study Open
Inflammatory bowel disease (IBD) patients are at risk for an impaired quality of life, for example, due to the chronic relapsing character of the disease. Even though there a numerous emerging IBD therapies these days, a cure of the diseas…