Mirjam Kohls
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View article: The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes
The efficacy of islet autoantibody screening with or without genetic pre-screening strategies for the identification of presymptomatic type 1 diabetes Open
Early detection of type 1 diabetes, in its presymptomatic stage, offers significant clinical advantages, including treatment that can delay disease onset. Current screening focuses on identifying islet autoantibody positivity, with propose…
View article: Associations between cardiometabolic comorbidities and mortality in adults with cancer: multinational cohort study
Associations between cardiometabolic comorbidities and mortality in adults with cancer: multinational cohort study Open
Objective To examine separate and joint associations between pre-existing cardiometabolic comorbidities and all cause and cause specific mortality in adults with cancer. Design Multinational cohort study. Setting Seven European countries f…
View article: EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents
EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents Open
Introduction The identification of type 1 diabetes at an early presymptomatic stage has clinical benefits. These include a reduced risk of diabetic ketoacidosis (DKA) at the clinical manifestation of the disease and a significant reduction…
View article: Discrimination and Precision of Continuous Glucose Monitoring in Staging Children With Presymptomatic Type 1 Diabetes
Discrimination and Precision of Continuous Glucose Monitoring in Staging Children With Presymptomatic Type 1 Diabetes Open
Context Staging and monitoring of presymptomatic type 1 diabetes includes the assessment for dysglycemia. Objective To assess the ability of continuous glucose monitoring (CGM) to differentiate between islet autoantibody-negative controls …
View article: A precise performance-based reimbursement model for the multi-centre NAPKON cohorts – development and evaluation
A precise performance-based reimbursement model for the multi-centre NAPKON cohorts – development and evaluation Open
Fair allocation of funding in multi-centre clinical studies is challenging. Models commonly used in Germany - the case fees (“fixed-rate model”, FRM) and up-front staffing and consumables (“up-front allocation model”, UFAM) lack transparen…
View article: Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON)
Definition of the Post-COVID syndrome using a symptom-based Post-COVID score in a prospective, multi-center, cross-sectoral cohort of the German National Pandemic Cohort Network (NAPKON) Open
Purpose The objective examination of the Post-COVID syndrome (PCS) remains difficult due to heterogeneous definitions and clinical phenotypes. The aim of the study was to verify the functionality and correlates of a recently developed PCS …
View article: Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-center, population-based cohort study
Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-center, population-based cohort study Open
In summary, our results suggest a strong link between post-COVID depression and fatigue, highlighting the need for integrative treatment approaches.
View article: Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-centre, population-based cohort study
Depression and fatigue six months post-COVID-19 disease are associated with overlapping symptom constellations: A prospective, multi-centre, population-based cohort study Open
Background: Depression and fatigue are commonly observed sequelae following viral diseases such as COVID-19. Identifying symptom constellations that differentially classify post-COVID depression and fatigue may be helpful to individualize …
View article: Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project
Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project Open
Purpose Despite the need to generate valid and reliable estimates of protection levels against SARS-CoV-2 infection and severe course of COVID-19 for the German population in summer 2022, there was a lack of systematically collected popula…
View article: Immune correlates against SARS-CoV-2 infection – results of population and hospital-based studies in the IMMUNEBRIDGE project in Germany, 2022
Immune correlates against SARS-CoV-2 infection – results of population and hospital-based studies in the IMMUNEBRIDGE project in Germany, 2022 Open
Einleitung In spring 2022, Germany lacked systematically collected population-based SARS-CoV-2 data allowing real-time assessment of protection levels against severe course of COVID-19. To fill this gap, the IMMUNEBRIDGE project, a joint c…
View article: Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men
Differential network interactions between psychosocial factors, mental health, and health-related quality of life in women and men Open
View article: SARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022
SARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022 Open
Purpose The study evaluates the effects on sero-immunity, health status and quality of life of children and adolescents after the upsurge of the Omicron variant in Germany. Methods This multicenter cross-sectional study (IMMUNEBRIDGE Kids)…
View article: Estimates of protection against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season - the IMMUNEBRIDGE project
Estimates of protection against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season - the IMMUNEBRIDGE project Open
Despite the need to generate valid and reliable estimates of protection against SARS-CoV-2 infection and severe course of COVID-19 for the German population in summer 2022, there was a lack of systematically collected population-based data…
View article: Consistency as a Data Quality Measure for German Corona Consensus Items Mapped from National Pandemic Cohort Network Data Collections
Consistency as a Data Quality Measure for German Corona Consensus Items Mapped from National Pandemic Cohort Network Data Collections Open
Background As a national effort to better understand the current pandemic, three cohorts collect sociodemographic and clinical data from coronavirus disease 2019 (COVID-19) patients from different target populations within the German Natio…
View article: Consistency as a Data Quality Measure for German Corona Consensus items mapped from National Pandemic Cohort Network data collections
Consistency as a Data Quality Measure for German Corona Consensus items mapped from National Pandemic Cohort Network data collections Open
Background As a national effort to better understand the current pandemic, three cohorts collect sociodemographic and clinical data from COVID-19 patients from different target populations within the German National Pandemic Cohort Network…
View article: Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients
Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients Open
View article: 2. Interimsanalyse des IMMUNEBRIDGE-Projektes zur Kommunikation von vorläufigen Ergebnissen an das Modellierungsnetz für schwere Infektionskrankheiten
2. Interimsanalyse des IMMUNEBRIDGE-Projektes zur Kommunikation von vorläufigen Ergebnissen an das Modellierungsnetz für schwere Infektionskrankheiten Open
Diese zweite Interimsanalyse stellt eine Datenzusammenführung von Daten verschiedener Studien (GUIDE, NAKO Gesundheitsstudie, MuSPAD, STAAB, paedSAXCOVID, Wü-KITa-CoV, Corkid, IMMUNEBRIDGE_ED) dar, die im Sommer 2022 von Juni bis Anfang Se…
View article: 2. Interimsanalyse des IMMUNEBRIDGE-Projektes zur Kommunikation von vorläufigen Ergebnissen an das Modellierungsnetz für schwere Infektionskrankheiten
2. Interimsanalyse des IMMUNEBRIDGE-Projektes zur Kommunikation von vorläufigen Ergebnissen an das Modellierungsnetz für schwere Infektionskrankheiten Open
<p>Diese zweite Interimsanalyse stellt eine Datenzusammenführung von Daten verschiedener Studien (GUIDE, NAKO Gesundheitsstudie, MuSPAD, STAAB, paedSAXCOVID, Wü-KITa-CoV, Corkid, IMMUNEBRIDGE_ED) dar, die im Sommer 2022 von…
View article: The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics Open
View article: Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study
Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study Open
View article: Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation
Key characteristics impacting survival of COVID-19 extracorporeal membrane oxygenation Open
View article: Impact of cumulative body mass index and cardiometabolic diseases on survival among patients with colorectal and breast cancer: a multi-centre cohort study
Impact of cumulative body mass index and cardiometabolic diseases on survival among patients with colorectal and breast cancer: a multi-centre cohort study Open
View article: NAPKON Public Use File
NAPKON Public Use File Open
Anonymized Public Use File of the National Pandemic Cohort Network (NAPKON), a German cohort studying the epidemiology and clinical course of SARS-CoV-2 infected patients. For more information see https://napkon.de/
View article: NAPKON Public Use File
NAPKON Public Use File Open
Anonymized Public Use File of the National Pandemic Cohort Network (NAPKON), a German cohort studying the epidemiology and clinical course of SARS-CoV-2 infected patients. For more information see https://napkon.de/
View article: The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics.
The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Open
The German government initiated the Network University Medicine (NUM) in early 2020 to improve national research activities on the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic. To this end, 36 German Academic Medic…
View article: Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP)
Long-term health sequelae and quality of life at least 6 months after infection with SARS-CoV-2: design and rationale of the COVIDOM-study as part of the NAPKON population-based cohort platform (POP) Open
View article: Identifying key environmental barriers experienced by persons with mild, moderate, or severe disability in Bankim Health District, Cameroon: a policy-targeted secondary analysis of data obtained with the World Bank and WHO model disability survey
Identifying key environmental barriers experienced by persons with mild, moderate, or severe disability in Bankim Health District, Cameroon: a policy-targeted secondary analysis of data obtained with the World Bank and WHO model disability survey Open