Mirna Pérez‐Moreno
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View article: Protocol for preparing mammalian skin samples encompassing hair follicles for spatial transcriptomics
Protocol for preparing mammalian skin samples encompassing hair follicles for spatial transcriptomics Open
Spatial transcriptomics enables a single-cell resolution view of gene expression patterns in tissues, providing insight into their biological functions. However, applying this approach to the skin presents inherent challenges. Here, we pre…
View article: Variation of extrachromosomal circular DNA in cancer cell lines
Variation of extrachromosomal circular DNA in cancer cell lines Open
View article: Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation
Wnt-mediated interactions of tumor-initiating cells with a macrophage niche drive skin tumor formation Open
Skin tumor-initiating stem cells (tSCs) fuel skin squamous cell carcinoma (SCC) formation and development in a complex tumor microenvironment, but a role for immune cells in the tSC niche governing the process of tumor formation has remain…
View article: Faculty Opinions recommendation of p120-catenin-dependent collective brain infiltration by glioma cell networks.
Faculty Opinions recommendation of p120-catenin-dependent collective brain infiltration by glioma cell networks. Open
Diffuse brain infiltration by glioma cells causes detrimental disease progression, however its multicellular coordination is poorly understood.We here show that glioma cells infiltrate brain collectively, as multicellular networks.Contacts…
View article: Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration
Dynamic interactions of lymphatic vessels at the hair follicle stem cell niche during hair regeneration Open
Lymphatic vessels (LV) are essential for skin fluid homeostasis and immune cell trafficking, but whether LV are associated with hair follicle (HF) regeneration is not known. Here, by using steady and live imaging approaches in mouse skin, …
View article: Isolation of Cancer Stem Cells from Squamous Cell Carcinoma
Isolation of Cancer Stem Cells from Squamous Cell Carcinoma Open
View article: Heterocellular cadherin connections: coordinating adhesive cues in homeostasis and cancer
Heterocellular cadherin connections: coordinating adhesive cues in homeostasis and cancer Open
This short insight covers some of the recent topics relevant to the field of cadherin–catenin adhesion in mediating connections between different cell types, so-called heterotypic or heterocellular connections, in both homeostasis and canc…
View article: Faculty Opinions recommendation of E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo.
Faculty Opinions recommendation of E-cadherin expression in macrophages dampens their inflammatory responsiveness in vitro, but does not modulate M2-regulated pathologies in vivo. Open
View article: Faculty Opinions recommendation of Roles for E-cadherin cell surface regulation in cancer.
Faculty Opinions recommendation of Roles for E-cadherin cell surface regulation in cancer. Open
View article: The transcription factor Slug represses <i>E-cadherin</i> expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
The transcription factor Slug represses <i>E-cadherin</i> expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors Open
There was an error published in J. Cell Sci. 116, 499–511.For the GST-Snail band-shift assay (right-hand panel) shown in Fig. 2, the incorrect data was inadvertently shown to represent the results of the competition with the 1000-fold unla…
View article: Faculty Opinions recommendation of Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity.
Faculty Opinions recommendation of Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity. Open
View article: A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy Open
The alterations in carbohydrate metabolism that fuel tumor growth have been extensively studied. However, other metabolic pathways involved in malignant progression, demand further understanding. Here we describe a metabolic acyl-CoA synth…
View article: Connections between cadherin-catenin proteins, spindle misorientation, and cancer
Connections between cadherin-catenin proteins, spindle misorientation, and cancer Open
Cadherin-catenin mediated adhesion is an important determinant of tissue architecture in multicellular organisms. Cancer progression and maintenance is frequently associated with loss of their expression or functional activity, which not o…
View article: Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors
Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors Open
Snail2 is a zinc finger transcription factor involved in driving epithelial to mesenchymal transitions. Snail2 null mice are viable, but display defects in melanogenesis, gametogenesis and hematopoiesis, and are markedly radiosensitive. He…