Miroslav Petrovec
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View article: Colorimetric RT-LAMP for SARS-CoV-2 detection from nasopharyngeal swabs or crude saliva: a multicountry diagnostic accuracy study in Africa
Colorimetric RT-LAMP for SARS-CoV-2 detection from nasopharyngeal swabs or crude saliva: a multicountry diagnostic accuracy study in Africa Open
View article: Safety, long-term effectiveness, and immunogenicity of varicella vaccination in children with juvenile idiopathic arthritis treated with biologic therapy
Safety, long-term effectiveness, and immunogenicity of varicella vaccination in children with juvenile idiopathic arthritis treated with biologic therapy Open
Objective: To evaluate safety, long-term effectiveness and immunogenicity of varicella vaccination in children with JIA, treated with biologic disease-modifying antirheumatic drugs (bDMARDs). Methods: This is a prospective case-control stu…
View article: European human granulocytic anaplasmosis is caused by a subcluster of Anaplasma phagocytophilum Ecotype I
European human granulocytic anaplasmosis is caused by a subcluster of Anaplasma phagocytophilum Ecotype I Open
Anaplasma phagocytophilum causes human granulocytic anaplasmosis. However, despite its ubiquitous presence in animals and ticks, human cases are rarely reported in Europe. We generated genetic data from A. phagocytophilum fro…
View article: Acute Human Bocavirus 1 Infection in Children Hospitalized for Acute Bronchiolitis: A 2-Year Prospective Study
Acute Human Bocavirus 1 Infection in Children Hospitalized for Acute Bronchiolitis: A 2-Year Prospective Study Open
Background: The objective of this prospective study was to assess the proportion and clinical consequences of human bocavirus 1 (HBoV1) replication in children hospitalized for acute bronchiolitis (AB) with HBoV1 DNA in the nasopharynx (NP…
View article: Influenza A, Influenza B, human respiratory syncytial virus and SARSCoV-2 molecular diagnostics and epidemiology in the post COVID-19 era
Influenza A, Influenza B, human respiratory syncytial virus and SARSCoV-2 molecular diagnostics and epidemiology in the post COVID-19 era Open
View article: Efficient SARS-CoV-2 variant detection and monitoring with Spike Screen next-generation sequencing
Efficient SARS-CoV-2 variant detection and monitoring with Spike Screen next-generation sequencing Open
The emergence and rapid spread of SARS-CoV-2 prompted the global community to identify innovative approaches to diagnose infection and sequence the viral genome because at several points in the pandemic positive case numbers exceeded the l…
View article: Sequencing analysis of SARS-CoV-2 cases in Slovenian long-term care facilities to support outbreak control
Sequencing analysis of SARS-CoV-2 cases in Slovenian long-term care facilities to support outbreak control Open
Introduction Residents of long-term care facilities (LTCFs) are at high risk of morbidity and mortality due to COVID-19, especially when new variants of concern (VOC) emerge. To provide intradisciplinary data in order to tailor public heal…
View article: Prirojena okužba s citomegalovirusom: priporočila za usmerjeno presejanje novorojenčkov in protokol obravnave
Prirojena okužba s citomegalovirusom: priporočila za usmerjeno presejanje novorojenčkov in protokol obravnave Open
Prirojena okužba s citomegalovirusom (pCMV) je v razvitih državah najpogostejša prirojena okužba ter najpogostejši vzrok za senzorinevralno okvaro sluha in razvojnonevrološke motnje. Le manjši delež otrok s pCMV ima ob rojstvu izražene zna…
View article: Herpesviridae and Atypical Bacteria Co-Detections in Lower Respiratory Tract Samples of SARS-CoV-2-Positive Patients Admitted to an Intensive Care Unit
Herpesviridae and Atypical Bacteria Co-Detections in Lower Respiratory Tract Samples of SARS-CoV-2-Positive Patients Admitted to an Intensive Care Unit Open
Shortly after the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cases of viral, bacterial, and fungal coinfections in hospitalized patients became evident. This retrospective study investigates the prevalence o…
View article: Seasonality and Genotype Diversity of Human Rhinoviruses during an Eight-Year Period in Slovenia
Seasonality and Genotype Diversity of Human Rhinoviruses during an Eight-Year Period in Slovenia Open
Due to the high socioeconomic burden of rhinoviruses, the development of prevention and treatment strategies is of high importance. Understanding the epidemiological and clinical features of rhinoviruses is essential in order to address th…
View article: Enterovirus D68 circulation between 2014 and 2022 in Slovenian children
Enterovirus D68 circulation between 2014 and 2022 in Slovenian children Open
Introduction Enterovirus D68 (EV-D68) belongs to the Picornaviridae family, genus Enterovirus . It is mostly known as a respiratory virus causing upper and lower respiratory tract infections, but it is also rarely associated with a variety…
View article: Influenza A, Influenza B, Human Respiratory Syncytial Virus and SARS-CoV-2 molecular diagnostics and epidemiology in the post COVID-19 era
Influenza A, Influenza B, Human Respiratory Syncytial Virus and SARS-CoV-2 molecular diagnostics and epidemiology in the post COVID-19 era Open
Background The concurrent circulation of SARS-CoV-2 with other respiratory viruses is unstoppable and represents a new diagnostic reality for clinicians and clinical microbiology laboratories. Multiplexed molecular testing on automated pla…
View article: Comparative Multi-Country Evaluation of Colorimetric Rt-Lamp for Sars-Cov-2 Detection from Nasopharyngeal Swabs or from Crude Saliva in Africa
Comparative Multi-Country Evaluation of Colorimetric Rt-Lamp for Sars-Cov-2 Detection from Nasopharyngeal Swabs or from Crude Saliva in Africa Open
View article: Enrichment of SARS-CoV-2 sequence from nasopharyngeal swabs whilst identifying the nasal microbiome
Enrichment of SARS-CoV-2 sequence from nasopharyngeal swabs whilst identifying the nasal microbiome Open
View article: Pseudo-outbreak of varicella-zoster virus associated with bronchoscopy in an intensive care unit
Pseudo-outbreak of varicella-zoster virus associated with bronchoscopy in an intensive care unit Open
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View article: Changes in HRSV Epidemiology but Not Circulating Variants in Hospitalized Children due to the Emergence of SARS-CoV-2
Changes in HRSV Epidemiology but Not Circulating Variants in Hospitalized Children due to the Emergence of SARS-CoV-2 Open
This study assesses the circulation of human respiratory syncytial virus (HRSV) genotypes before, during, and toward the end of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic in children and determines the influe…
View article: A simplified nasopharyngeal swab collection procedure for minimizing patient discomfort while retaining sample quality
A simplified nasopharyngeal swab collection procedure for minimizing patient discomfort while retaining sample quality Open
A nasopharyngeal swab (NPS) is the most frequently collected sample type when molecular diagnosis of respiratory viruses, including SARS CoV-2, is required. An optimal collection technique would provide sufficient sample quality for the di…
View article: Molecular Typing of Mastadenoviruses in Simultaneously Collected Nasopharyngeal Swabs and Stool Samples from Children Hospitalized for Acute Bronchiolitis, Acute Gastroenteritis, and Febrile Seizures
Molecular Typing of Mastadenoviruses in Simultaneously Collected Nasopharyngeal Swabs and Stool Samples from Children Hospitalized for Acute Bronchiolitis, Acute Gastroenteritis, and Febrile Seizures Open
This study determines and compares the frequency of human mastadenovirus (HAdV) presence in children with acute bronchiolitis (AB), acute gastroenteritis (AGE), and febrile seizures (FS), ascertains types of HAdVs associated with each indi…
View article: Characterisation of the Antibody Response in Sinopharm (BBIBP-CorV) Recipients and COVID-19 Convalescent Sera from the Republic of Moldova
Characterisation of the Antibody Response in Sinopharm (BBIBP-CorV) Recipients and COVID-19 Convalescent Sera from the Republic of Moldova Open
The early availability of effective vaccines against SARS-CoV-2, the aetiologic cause of COVID-19, has been at the cornerstone of the global recovery from the pandemic. This study aimed to assess the antispike RBD IgG antibody titres and n…
View article: Enrichment of Sars-Cov-2 and Seasonal Coronavirus Sequence from Nasopharyngeal Swabs Whilst Maintaining the Background Context of the Microbiome
Enrichment of Sars-Cov-2 and Seasonal Coronavirus Sequence from Nasopharyngeal Swabs Whilst Maintaining the Background Context of the Microbiome Open
View article: Evaluation of Two Broadly Used Commercial Methods for Detection of Respiratory Viruses with a Recently Added New Target for Detection of SARS-CoV-2
Evaluation of Two Broadly Used Commercial Methods for Detection of Respiratory Viruses with a Recently Added New Target for Detection of SARS-CoV-2 Open
The clinical symptoms caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are nonspecific and can be associated with most other respiratory viruses that cause acute respiratory tract infections (ARI). Because the cli…
View article: Respiratory Viruses in Hospitalized Patients before and after SARS-CoV-2
Respiratory Viruses in Hospitalized Patients before and after SARS-CoV-2 Open
Background: Since the emergence of COVID-19, countries have implemented combinations of non-pharmaceutical measures not only to contain the COVID-19 cases manageable for their healthcare system but also to reduce the economic burden of the…
View article: Performance of nasopharyngeal swab and saliva in detecting Delta and Omicron SARS‐CoV‐2 variants
Performance of nasopharyngeal swab and saliva in detecting Delta and Omicron SARS‐CoV‐2 variants Open
A prospective cohort study was conducted during the Delta and Omicron severe acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2) epidemic waves from paired nasopharyngeal swab (NPS or NP swab) and saliva samples taken from 624 parti…
View article: Okužba s citomegalovirusom v nosečnosti
Okužba s citomegalovirusom v nosečnosti Open
Citomegalovirus (CMV) je najpogostejši virusni vzrok okužbe ploda v maternici. Virus je nevrotropen, zato povzroča predvsem nevrološke zaplete. Je najpogostejši negenetski vzrok senzorinevralne naglušnosti, nevroloških nepravilnosti in ums…
View article: Postnatal CMV Infection and Antiviral Treatment in Extremely Premature Infants: A 12-Year Retrospective Analysis
Postnatal CMV Infection and Antiviral Treatment in Extremely Premature Infants: A 12-Year Retrospective Analysis Open
Background: The impact and outcomes of postnatal cytomegalovirus (CMV) infection are not entirely clear. We aimed to determine the associations between treatment outcomes of postnatal CMV infection and its antiviral treatment. Methods: Ret…
View article: Genetic Characterisation and Comparison of Three Human Coronaviruses (HKU1, OC43, 229E) from Patients and Bovine Coronavirus (BCoV) from Cattle with Respiratory Disease in Slovenia
Genetic Characterisation and Comparison of Three Human Coronaviruses (HKU1, OC43, 229E) from Patients and Bovine Coronavirus (BCoV) from Cattle with Respiratory Disease in Slovenia Open
Coronaviruses (CoV) are widely distributed pathogens of human and animals and can cause mild or severe respiratory and gastrointestinal disease. Antigenic and genetic similarity of some CoVs within the Betacoronavirus genus is evident. The…
View article: Seroprevalence of severe acute respiratory syndrome coronavirus 2 in Slovenia: results of two rounds of a nationwide population study on a probability-based sample, challenges and lessons learned
Seroprevalence of severe acute respiratory syndrome coronavirus 2 in Slovenia: results of two rounds of a nationwide population study on a probability-based sample, challenges and lessons learned Open
SARS-CoV-2 seroprevalence in Slovenia increased four-fold from late April to October/November 2020, mainly due to a devastating second wave. Significant logistic/methodological challenges accompanied both rounds. The main lessons learned w…
View article: Characterization of Tularemia Cases in Slovenia with Multiple-Locus Variable-Number Tandem Repeat Analysis
Characterization of Tularemia Cases in Slovenia with Multiple-Locus Variable-Number Tandem Repeat Analysis Open
Francisella tularensis is the etiologic agent of tularemia, a bacterial zoonotic disease. The genome of F. tularensis shows a recent evolutionary change, especially in reservoirs. Variable number of tandem repeats (VNTR) is d…
View article: The Importance of Biobanking for Response to Pandemics Caused by Emerging Viruses: The European Virus Archive As an Observatory of the Global Response to the Zika Virus and COVID-19 Crisis
The Importance of Biobanking for Response to Pandemics Caused by Emerging Viruses: The European Virus Archive As an Observatory of the Global Response to the Zika Virus and COVID-19 Crisis Open
When a new virus emerges and causes a significant epidemic, the emergency response relies on diagnostics, surveillance, testing, and proposal of treatments if they exist, and also in the longer term, redirection of research efforts toward …
View article: Comparison of Lymphocyte Populations in Patients With Dobrava or Puumala orthohantavirus Infection
Comparison of Lymphocyte Populations in Patients With Dobrava or Puumala orthohantavirus Infection Open
Hemorrhagic fever with renal syndrome (HFRS), caused by Dobrava (DOBV) and Puumala (PUUV) orthohantaviruses, is an endemic disease in Slovenia. DOBV is mainly responsible for a more severe disease, whereas PUUV usually causes a milder form…