Alireza Mirzaei
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View article: Osteoporotic fractures in adults under 65 without prior indications for BMD testing: a call to reevaluate screening guidelines
Osteoporotic fractures in adults under 65 without prior indications for BMD testing: a call to reevaluate screening guidelines Open
Among the 1,248 patients analyzed, 772 (61.9%) were under 65 years. Of these, only 34% had indications for BMD testing according to the International Society for Clinical Densitometry (ISCD) guidelines. Fragility fractures after age 40, sm…
View article: Osteoarticular allograft versus prosthetic allograft composites: which reconstruction method results in superior outcomes following the resection of proximal femur tumor in adolescent and preadolescent patients?
Osteoarticular allograft versus prosthetic allograft composites: which reconstruction method results in superior outcomes following the resection of proximal femur tumor in adolescent and preadolescent patients? Open
OA and APC reconstructions of the proximal femur following tumor resection in adolescent and preadolescent patients each have their benefits and associated complications. However, APC reconstruction appears to provide superior limb functio…
View article: The combination effect of treadmill exercise and valerian hydroalcoholic extract on the heart of type 2 diabetic rats
The combination effect of treadmill exercise and valerian hydroalcoholic extract on the heart of type 2 diabetic rats Open
Objectives: Diabetes mellitus is a metabolic disorder recognized for inducing endothelial dysfunction in coronary arteries. This study aimed to investigate the synergistic effects of valerian hydroalcoholic extract and exercise in diabetic…
View article: Pre-aspiration outpatient ultrasound can accurately predict dry taps in prosthetic hips suspected of infection; a prospective study
Pre-aspiration outpatient ultrasound can accurately predict dry taps in prosthetic hips suspected of infection; a prospective study Open
Introduction Aspiration represents the most potent method for exploring the potential occurrence of Periprosthetic Joint Infection (PJI). However, dry taps are common. While aspiration under ultrasound (US) guidance in the radiology depart…
View article: Prediction of subsequent fragility fractures: application of machine learning
Prediction of subsequent fragility fractures: application of machine learning Open
View article: Outcomes of ilium and iliosacral Ewing’s sarcoma resection reconstructed with tibial strut allograft
Outcomes of ilium and iliosacral Ewing’s sarcoma resection reconstructed with tibial strut allograft Open
Aims Ilium is the most common site of pelvic Ewing’s sarcoma (ES). Resection of the ilium and iliosacral joint causes pelvic disruption. However, the outcomes of resection and reconstruction are not well described. In this study, we report…
View article: Erratum to: Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients?
Erratum to: Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients? Open
In the study, "Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients?" [1], the number of patients treated between 2005 and 2018 was incorrectly reported as 23. The correct numb…
View article: Effect of Cognitive-Behavioral Therapy on the Oxidative Balance of Fibromyalgia Patients: A Randomized Controlled Trial
Effect of Cognitive-Behavioral Therapy on the Oxidative Balance of Fibromyalgia Patients: A Randomized Controlled Trial Open
Background: Cognitive-behavioral therapy (CBT) is acknowledged as an efficient therapeutic modality in fibromyalgia. However, its effect on the oxidative balance of fibromyalgia patients has not been investigated. Objectives: We investigat…
View article: Outcomes of Megaprosthesis Reconstruction for the Salvage of Failed Osteoarticular Allograft Around the Knee implanted before Skeletal Maturity in Primary Bone Sarcoma: A Case-Series.
Outcomes of Megaprosthesis Reconstruction for the Salvage of Failed Osteoarticular Allograft Around the Knee implanted before Skeletal Maturity in Primary Bone Sarcoma: A Case-Series. Open
Megaprosthesis is a viable option for salvaging failed osteoarticular allografts around the knee. It also provides the opportunity to correct the limb length discrepancy.
View article: Prediction of repeat fragility fractures: Application of machine learning
Prediction of repeat fragility fractures: Application of machine learning Open
Background Despite the exceptional performance of machine learning (ML) in modern medical research, it is rarely used for repeated-fracture prediction in osteoporotic patients. In this study, we aim to evaluate the predictive capability of…
View article: The expression changes of PD-L1 and immune response mediators are related to the severity of primary bone tumors
The expression changes of PD-L1 and immune response mediators are related to the severity of primary bone tumors Open
The expression pattern, diagnostic value, and association of PD-L1, IFN-γ and TGF-β with bone tumor type, severity, and relapse are determined in this study. 300 human samples from patients with osteosarcoma, Ewing sarcoma, and GCT were en…
View article: The clinical significance of CD44v6 in malignant and benign primary bone tumors
The clinical significance of CD44v6 in malignant and benign primary bone tumors Open
Background The objective of this study was to assess the expression profile of CD44v6, a potential cancer stem cell marker, and its diagnostic and predictive significance in three distinct types of primary bone tumors. Methods In this stud…
View article: IODnet: Indoor/Outdoor Telecommunication Signal Detection through Deep Neural Network
IODnet: Indoor/Outdoor Telecommunication Signal Detection through Deep Neural Network Open
In many Internet of Things (IoT) applications, knowing the device's location can be quite important for some reasons such as asset tracking and inventory management, geolocation services, safety and security, environmental monitoring, and …
View article: Establishment of Iran Musculoskeletal Tumor Registry: A Study Protocol and Lessons Learned from Implementation and the Pilot Phase
Establishment of Iran Musculoskeletal Tumor Registry: A Study Protocol and Lessons Learned from Implementation and the Pilot Phase Open
The main lessons learned were to develop a monitoring system to make sure that the new staff is adequately trained for the registration process as well as avoid the inclusion of time-consuming useless data in the minimum data set.
View article: Scapular Osteosarcoma Treated by Scapulectomy with or Without Scapular Allograft: A Retrospective Case Series
Scapular Osteosarcoma Treated by Scapulectomy with or Without Scapular Allograft: A Retrospective Case Series Open
View article: Evaluating the local expression pattern of IGF-1R in tumor tissues and the circulating levels of IGF-1, IGFBP-1, and IGFBP-3 in the blood of patients with different primary bone tumors
Evaluating the local expression pattern of IGF-1R in tumor tissues and the circulating levels of IGF-1, IGFBP-1, and IGFBP-3 in the blood of patients with different primary bone tumors Open
Introduction The present study tried to provide insights into the expression pattern and diagnostic significance of the IGF-1 axis main mediators in three main primary bone tumor types with different degrees of severity. Methods The real-t…
View article: Total Synovectomy and Bone Grafting/Cementation after Curettage of the Bone Lesion in Diffuse Type of Tenosynovial Giant Cell Tumor: A Retrospective Cohort Study.
Total Synovectomy and Bone Grafting/Cementation after Curettage of the Bone Lesion in Diffuse Type of Tenosynovial Giant Cell Tumor: A Retrospective Cohort Study. Open
Curettage and filling the defect with bone graft or cement are adequate treatments for managing bone lesions in D-TGCT.
View article: The Expression Pattern of Non-apoptotic Cell Death Pathway in Osteosarcoma: Necroptosis and Autophagy as Backup Mechanisms for Therapeutics Strategy
The Expression Pattern of Non-apoptotic Cell Death Pathway in Osteosarcoma: Necroptosis and Autophagy as Backup Mechanisms for Therapeutics Strategy Open
Background: Among the primary bone tumors, osteosarcoma accounts for a malignant tumor with a high rate of progression and poor prognosis. Despite the achievement of combined therapy regimens in improving patients’ overall survival, patien…
View article: Expression pattern and clinical significance of β-catenin gene and protein in patients with primary malignant and benign bone tumors
Expression pattern and clinical significance of β-catenin gene and protein in patients with primary malignant and benign bone tumors Open
View article: Non-spinal Hydatid Disease of Bone: A Series of Nine Cases.
Non-spinal Hydatid Disease of Bone: A Series of Nine Cases. Open
Osseous hydatid disease is a serious disease with challenging diagnosis, difficult treatment, and significant morbidity. Preoperative diagnosis is generally easier in flat bones. Radical resection is the optimal treatment of this disease, …
View article: Ganglion Cyst of the Thenar Muscle: A Case Report
Ganglion Cyst of the Thenar Muscle: A Case Report Open
Ganglion cysts are the most common type of soft tissue tumors in the hands and wrists. When presented in rare locations, they may cause diagnostic and therapeutic challenges. In this report, we presented a case of a ganglion cyst in the th…
View article: Effects of Core Decompression and Local Deferoxamine Injection on Clinical Outcomes and Revascularization of Lunate Carpal Bone in Kienbock Disease: A Pilot Study
Effects of Core Decompression and Local Deferoxamine Injection on Clinical Outcomes and Revascularization of Lunate Carpal Bone in Kienbock Disease: A Pilot Study Open
Background: Avascular necrosis of the lunate or Kienböck disease is a rare disorder with unknown etiology and challenging treatment. Objectives: In this study, we evaluated the effects of local deferoxamine injection as an angiogenic mole…
View article: Effects of cleft lip and palate on temporomandibular joint components: a CBCT study
Effects of cleft lip and palate on temporomandibular joint components: a CBCT study Open
Introduction: To assess the effects of cleft lip and palate (CLP) on the temporomandibular joint (TMJ) components using cone-beam computed tomography (CBCT). Methodology: This historical cohort study evaluated 20 CBCT scans of the TMJ area…
View article: Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients?
Are Fibular Allograft Struts Useful for Unicameral Bone Cysts of the Proximal Humerus in Skeletally Mature Patients? Open
Background Although most unicameral bone cysts (UBCs) are either successfully treated or have healed by the time of skeletal maturity, a small proportion of patients will have persistent UBCs beyond the age of skeletal maturity. More relia…
View article: How the Choice of Osteosynthesis Affects the Complication Rate of Intercalary Allograft Reconstruction? A Systematic Review and Meta-analysis
How the Choice of Osteosynthesis Affects the Complication Rate of Intercalary Allograft Reconstruction? A Systematic Review and Meta-analysis Open
View article: Upregulation of Ganglioside GD2 Synthase (GD2S), as a New Putative Cancer Stem Cell Marker in Breast Carcinomas
Upregulation of Ganglioside GD2 Synthase (GD2S), as a New Putative Cancer Stem Cell Marker in Breast Carcinomas Open
Background: GD2 synthase (GD2S) is the key enzyme required for ganglioside GD2 synthesis. It is commonly expressed in normal tissues and various cancers. Ganglioside GD2 is identified as a breast cancer stem cells (BCSCs) marker tha…
View article: Effect of 8 weeks of Endurance Training and Hydroalcoholic Extract of Olive Leaf on Coronary Vascular Bed Endothelial Disorder and Lipid Profile in Diabetic Male Rats
Effect of 8 weeks of Endurance Training and Hydroalcoholic Extract of Olive Leaf on Coronary Vascular Bed Endothelial Disorder and Lipid Profile in Diabetic Male Rats Open
Background and purpose: Due to the high rate of diabetes in the community and the importance of herbal supplements and exercise in its treatment, the present study aimed at evaluating the effects of hydroalcoholic extract of olive leaf on …
View article: Does GD2 synthase (GD2S) detect cancer stem cells in blood samples of breast carcinomas?
Does GD2 synthase (GD2S) detect cancer stem cells in blood samples of breast carcinomas? Open
Higher expression of GD2S in BC samples compared to healthy control indicates the potential utility of GD2S as a marker of malignancy.
View article: Evaluation of local and circulating osteopontin in malignant and benign primary bone tumors
Evaluation of local and circulating osteopontin in malignant and benign primary bone tumors Open
View article: Risk of infection in postmenopausal women with rheumatoid arthritis and osteoporosis taking denosumab and bDMARDS
Risk of infection in postmenopausal women with rheumatoid arthritis and osteoporosis taking denosumab and bDMARDS Open
Background: There is no clear consensus regarding the potential of denosumab for increasing the risk of infection in patients who concurrently receive biologic disease-modifying anti-rheumatic drugs (bDMARDs). In this study, we comp…