Misato Chimura
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View article: Finerenone and Quality of Life Assessed Using the EuroQol 5-Dimension Questionnaire Level-Sum-Score in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction
Finerenone and Quality of Life Assessed Using the EuroQol 5-Dimension Questionnaire Level-Sum-Score in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction Open
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View article: Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trial
Serum magnesium and outcomes in heart failure with reduced ejection fraction: the GALACTIC-HF trial Open
Background and Aims The frequency and prognostic significance of abnormalities in serum magnesium concentrations have not been described in a contemporary HF population. The authors evaluated the prognostic significance of magnesium concen…
View article: Efficacy and Tolerability of Finerenone According to the Use and Dosage of Diuretics
Efficacy and Tolerability of Finerenone According to the Use and Dosage of Diuretics Open
Importance Given their kidney actions, it is important to evaluate the efficacy and safety of mineralocorticoid receptor antagonists when combined with other diuretics and whether they have a so-called diuretic-sparing effect in patients w…
View article: An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells
An on-chip deformability checker demonstrates that the severity of iron deficiency is associated with increased deformability of red blood cells Open
The deformability of red blood cells (RBCs) is essential for peripheral circulation and RBC survival and is reportedly altered in several diseases. However, its detail in iron-deficiency (ID) anemia remains poorly understood. We investigat…
View article: Variations in management strategies for stable coronary artery disease in the Asia-Pacific region: Insights from a multinational survey
Variations in management strategies for stable coronary artery disease in the Asia-Pacific region: Insights from a multinational survey Open
Introduction: Randomised controlled trials (RCTs) have informed guideline recommendations for the management of stable coronary artery disease (CAD). However, the real-world impact of contemporary guidelines and trials on practising physic…
View article: Anaemia in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified analysis of the <scp>FINEARTS</scp>‐<scp>HF</scp> trial
Anaemia in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified analysis of the <span>FINEARTS</span>‐<span>HF</span> trial Open
Aims Anaemia is common in heart failure with mildly reduced or preserved ejection fraction (HFmrEF/HFpEF) and associated with poor clinical outcomes. While renin–angiotensin system blockers reduce haemoglobin, little is known about the eff…
View article: Comprehensive Analysis of the Effects of Sacubitril/Valsartan According to Sex Among Patients With Heart Failure and Reduced Ejection Fraction in PARADIGM‐HF
Comprehensive Analysis of the Effects of Sacubitril/Valsartan According to Sex Among Patients With Heart Failure and Reduced Ejection Fraction in PARADIGM‐HF Open
Background Women with heart failure (HF) ejection fraction appeared to respond more favorably to sacubitril/valsartan, compared with valsartan, than men in PARAGON‐HF (Prospective Comparison of ARNI With ARB Global Outcomes in Heart Failur…
View article: Characteristics and Clinical Impact of Work‐Related Musculoskeletal Disorders in Echocardiography—Workplace Injuries Improvement Among Sonographers in Echocardiography (WIISE) Study
Characteristics and Clinical Impact of Work‐Related Musculoskeletal Disorders in Echocardiography—Workplace Injuries Improvement Among Sonographers in Echocardiography (WIISE) Study Open
Work‐related musculoskeletal disorders (WRMSD) are painful injuries affecting health practitioners who perform sonography, and yet its prevalence in Asia Pacific is largely unknown. The aim of the survey is to understand WRMSD among sonogr…
View article: Primary Prevention of Cardiovascular Disease in Asia: Challenges
Primary Prevention of Cardiovascular Disease in Asia: Challenges Open
Asia is a large continent that comprises diverse populations with varying cultures, socioeconomic status, and health literacy levels. Effective preventive cardiology may require differential health care resource allocation and financing mo…
View article: Primary Prevention of Cardiovascular Disease in Asia: Opportunities and Solutions
Primary Prevention of Cardiovascular Disease in Asia: Opportunities and Solutions Open
A differential approach addressing cardiovascular risk factor screening, prevention, and management that considers the context-specific socioeconomic, governmental, and cultural aspects in diverse Asian populations may help reduce the rapi…
View article: Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy
Electron microscopic findings predict clinical outcomes in patients with non‐ischaemic cardiomyopathy Open
Aims Electron microscopy reveals microstructural alterations in cardiomyocyte nuclei and myofilaments in non‐ischaemic cardiomyopathy (NICM), particularly in dilated cardiomyopathy (DCM). Nevertheless, the correlation between such observat…
View article: Overview of the Burden and Challenges of Hypertension in Asia-Pacific
Overview of the Burden and Challenges of Hypertension in Asia-Pacific Open
There remains great heterogeneity in the availability of data and approaches in managing hypertension in Asia-Pacific. A narrative review was performed to better understand the epidemiology of hypertension and challenges in hypertension ca…
View article: Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction
Finerenone in Women and Men With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Open
Importance Sex is associated with the clinical presentation, outcomes, and response to treatment in patients with heart failure (HF). However, little is known about the safety and efficacy of treatment with finerenone according to sex. Obj…
View article: Finerenone Improves Outcomes in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Irrespective of Age: A Prespecified Analysis of FINEARTS-HF
Finerenone Improves Outcomes in Patients With Heart Failure With Mildly Reduced or Preserved Ejection Fraction Irrespective of Age: A Prespecified Analysis of FINEARTS-HF Open
BACKGROUND: Finerenone improves outcomes in patients with heart failure and mildly reduced or preserved ejection fraction. It is important to understand the efficacy and safety of finerenone in these patients according to age. METHODS: The…
View article: Ratio of pulmonary artery diameter to ascending aortic diameter and its association with right ventricular failure after left ventricular assist device implantation
Ratio of pulmonary artery diameter to ascending aortic diameter and its association with right ventricular failure after left ventricular assist device implantation Open
Combining non-invasive parameters with the PAD/AoD ratio can predict RVF with high accuracy.
View article: Cardiovascular Care and Research in the Asia-Pacific Region during the COVID-19 Pandemic: Insights from Early and Mid-career Physicians
Cardiovascular Care and Research in the Asia-Pacific Region during the COVID-19 Pandemic: Insights from Early and Mid-career Physicians Open
Background: The COVID-19 pandemic imposed a significant burden on healthcare systems in the Asia-Pacific region and has had a varying impact on physicians at different stages of their career. This study sought to evaluate the personal pers…
View article: Correction: Novel indices representing heterogeneous distributions of myocardial perfusion imaging
Correction: Novel indices representing heterogeneous distributions of myocardial perfusion imaging Open
View article: Novel indices representing heterogeneous distributions of myocardial perfusion imaging
Novel indices representing heterogeneous distributions of myocardial perfusion imaging Open
View article: Diverse distribution patterns of segmental longitudinal strain are associated with different clinical features and outcomes in dilated cardiomyopathy
Diverse distribution patterns of segmental longitudinal strain are associated with different clinical features and outcomes in dilated cardiomyopathy Open
View article: Novel indices representing heterogeneous distributions of myocardial perfusion imaging
Novel indices representing heterogeneous distributions of myocardial perfusion imaging Open
Introduction Heterogeneous distribution in myocardial perfusion images (MPI) obtained by scintigraphy is often observed in cardiac diseases with normal myocardial perfusion. However, quantitative assessments of such heterogeneity have not …
View article: Mitochondrial function and coronary flow reserve improvement after autologous myoblast patch transplantation for ischaemic cardiomyopathy: a case report
Mitochondrial function and coronary flow reserve improvement after autologous myoblast patch transplantation for ischaemic cardiomyopathy: a case report Open
Background Autologous myoblast patch (AMP) transplantation has resulted in good clinical outcomes for end-stage ischaemic cardiomyopathy, but the mechanisms behind them are unclear. Herein, we report the relationship between mitochondrial …
View article: Evaluation of the efficacy and safety of an integrated telerehabilitation platform for home-based cardiac REHABilitation in patients with heart failure (E-REHAB): protocol for a randomised controlled trial
Evaluation of the efficacy and safety of an integrated telerehabilitation platform for home-based cardiac REHABilitation in patients with heart failure (E-REHAB): protocol for a randomised controlled trial Open
Introduction Cardiac rehabilitation (CR) is strongly recommended as a medical treatment to improve the prognosis and quality of life of patients with heart failure (HF); however, participation rates in CR are low compared with other eviden…
View article: Late gadolinium enhancement on cardiac magnetic resonance combined with 123I- metaiodobenzylguanidine scintigraphy strongly predicts long-term clinical outcome in patients with dilated cardiomyopathy
Late gadolinium enhancement on cardiac magnetic resonance combined with 123I- metaiodobenzylguanidine scintigraphy strongly predicts long-term clinical outcome in patients with dilated cardiomyopathy Open
Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) is limited in its ability to detect diffuse interstitial fibrosis, which is commonly found in idiopathic dilated cardiomyopathy (DCM). On the other hand, Washout rate (W…
View article: Improvement of left ventricular function assessment by global longitudinal strain after successful percutaneous coronary intervention for chronic total occlusion
Improvement of left ventricular function assessment by global longitudinal strain after successful percutaneous coronary intervention for chronic total occlusion Open
The benefit of revascularization of chronic total occlusion (CTO) in percutaneous coronary intervention (PCI) is controversial. On the other hand, left ventricular (LV) global longitudinal strain (GLS) is a more sensitive marker of LV myoc…
View article: Simple Electrocardiographic Score Can Predict Left Ventricular Reverse Remodeling in Patients With Non-Ischemic Cardiomyopathy
Simple Electrocardiographic Score Can Predict Left Ventricular Reverse Remodeling in Patients With Non-Ischemic Cardiomyopathy Open
Background: Left ventricular reverse remodeling (LVRR) is a favorable response in non-ischemic, non-valvular cardiomyopathy (NICM) patients. Recently, 18-lead body surface electrocardiography (ECG), the standard 12-lead ECG …
View article: Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota
Non-Ischemic Heart Failure With Reduced Ejection Fraction Is Associated With Altered Intestinal Microbiota Open
Non-ischemic HFrEF patients exhibited multidimensional differences in intestinal microbial communities compared with healthy subjects.
View article: On-Chip RBCs Deformability Tracker by Parallel Constriction Channels
On-Chip RBCs Deformability Tracker by Parallel Constriction Channels Open
This paper proposes a method for automatic evaluation of red blood cell using a microfluidic chip. The evaluation is based on cell velocity and deformation through parallel microchannels. In conventional works, the evaluation is performed …
View article: Impact of esophageal temperature monitoring guided atrial fibrillation ablation on preventing asymptomatic excessive transmural injury
Impact of esophageal temperature monitoring guided atrial fibrillation ablation on preventing asymptomatic excessive transmural injury Open
Background Even with the use of a reduced energy setting (20–25 W), excessive transmural injury (ETI) following catheter ablation of atrial fibrillation (AF) is reported to develop in 10% of patients. However, the incidence of ETI depends …
View article: Usefulness of non–contrast‐enhanced MRI with two‐dimensional balanced steady‐state free precession for the acquisition of the pulmonary venous and left atrial anatomy pre catheter ablation of atrial fibrillation: Comparison with contrast enhanced CT in clinical cases
Usefulness of non–contrast‐enhanced MRI with two‐dimensional balanced steady‐state free precession for the acquisition of the pulmonary venous and left atrial anatomy pre catheter ablation of atrial fibrillation: Comparison with contrast enhanced CT in clinical cases Open
Background To investigate the feasibility of substituting non–contrast‐enhanced MR (non–CE‐MR) imaging with a two‐dimensional (2D) balanced steady‐state free precession (b‐SSFP) sequence for contrast‐enhanced computed tomography (CE‐CT) fo…