Misha Luyer
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View article: Quality of life in patients with gallbladder polyps: a multicentre prospective cohort study.
Quality of life in patients with gallbladder polyps: a multicentre prospective cohort study. Open
View article: [18F]F-FAPI PET/CT and LAparoscopy in STagIng advanced gastric Cancer: a multicenter prospective study (PLASTIC-3 study)
[18F]F-FAPI PET/CT and LAparoscopy in STagIng advanced gastric Cancer: a multicenter prospective study (PLASTIC-3 study) Open
ClinicalTrials.gov, NCT07018661. This trial was registered prospectively on June 12th, 2025.
View article: Methadone as an Additive to Multimodal Analgesia vs Epidural Analgesia in Open and Minimal Invasive Pancreatic Surgery: A Retrospective Analysis
Methadone as an Additive to Multimodal Analgesia vs Epidural Analgesia in Open and Minimal Invasive Pancreatic Surgery: A Retrospective Analysis Open
Background Epidural analgesia (EA) is widely used in pancreatic surgery but is associated with hypotension and delayed recovery. The shift towards minimally invasive surgery has led to exploration of alternative multimodal analgesia strate…
View article: Nationwide outcomes of 1000 robotic pancreatoduodenectomies across the four phases of the learning curve
Nationwide outcomes of 1000 robotic pancreatoduodenectomies across the four phases of the learning curve Open
Background Robotic pancreatoduodenectomy (RPD) is increasingly being implemented to enhance patient recovery, but it is unclear what happens to patient outcomes after the initial learning curve. The aim of this study was to evaluate the fi…
View article: Length of hospital stay after uncomplicated gastrectomy in the Netherlands: a nationwide cohort study
Length of hospital stay after uncomplicated gastrectomy in the Netherlands: a nationwide cohort study Open
Background Longer length of hospital stay (LOS) has an impact on patient lives and hospital costs. As 60%–70% of gastrectomies are uncomplicated, identifying factors influencing LOS after uncomplicated gastrectomy could help reduce LOS. Th…
View article: Phase I study of intraperitoneal irinotecan with systemic capecitabine and oxaliplatin for patients with gastric peritoneal metastases
Phase I study of intraperitoneal irinotecan with systemic capecitabine and oxaliplatin for patients with gastric peritoneal metastases Open
Administration of 3-weekly CBIP irinotecan concomitant to systemic CAPOX was well tolerated at 75 mg in patients with gastric cancer and peritoneal metastases. Giving its promising clinical outcomes and the safety profile, CBIP of irinotec…
View article: Role of Intestinal Fatty Acid Binding Protein in Diagnosing Adhesive Small Bowel Obstruction: A Pilot Study
Role of Intestinal Fatty Acid Binding Protein in Diagnosing Adhesive Small Bowel Obstruction: A Pilot Study Open
Introduction: The incidence of adhesive small bowel obstruction (ASBO) after abdominal surgery is 2.4%. Delay in surgery increases morbidity and mortality. Plasma intestinal fatty acid binding protein (I-FABP) levels indicate intestinal da…
View article: Clinical insights to improve medical deep learning design: A comprehensive review of methods and benefits
Clinical insights to improve medical deep learning design: A comprehensive review of methods and benefits Open
The success of deep learning and computer vision of natural images has led to an increased interest in medical image deep learning applications. However, introducing black-box deep learning models leaves little room for domain-specific kno…
View article: Revised Guidelines for the Treatment and Follow‐Up of Gallbladder Polyps Do Not Reduce Unwarranted Cholecystectomies: Results of the POLYP Study
Revised Guidelines for the Treatment and Follow‐Up of Gallbladder Polyps Do Not Reduce Unwarranted Cholecystectomies: Results of the POLYP Study Open
Background Gallbladder polyps are seen in up to 7% of adults and carry a low malignancy risk. Guidelines on indication for surgery and follow‐up remain controversial because of regional differences in the development of malignancy. This st…
View article: Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort
Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort Open
View article: Oncological outcome after robot-assisted <i>versus</i> open pancreatoduodenectomy for upfront resectable cancer in the pancreatic head: a nationwide cohort analysis
Oncological outcome after robot-assisted <i>versus</i> open pancreatoduodenectomy for upfront resectable cancer in the pancreatic head: a nationwide cohort analysis Open
Background Robot-assisted pancreatoduodenectomy (RPD) aims to enhance postoperative recovery compared to open pancreatoduodenectomy (OPD). Although recent randomized trials confirmed the short-term safety of RPD, they did not confirm super…
View article: Robot-assisted and Laparoscopic Extended Left Pancreatectomy
Robot-assisted and Laparoscopic Extended Left Pancreatectomy Open
Objective: To compare postoperative outcomes after extended robot-assisted left pancreatectomy (e-RLP) and extended laparoscopic left pancreatectomy (e-LLP). Summary Background Data: The implementation of RLP is increasing worldwide with e…
View article: Online video versus face-to-face preoperative consultation for major abdominal surgery (VIDEOGO): a multicentre, open-label, randomised, controlled, non-inferiority trial
Online video versus face-to-face preoperative consultation for major abdominal surgery (VIDEOGO): a multicentre, open-label, randomised, controlled, non-inferiority trial Open
The Netherlands Organization for Health Research and Development.
View article: Intrathoracic <i>versus</i> cervical anastomosis after totally or hybrid minimally invasive transthoracic oesophagectomy for oesophageal cancer: cost-effectiveness analysis alongside the randomized ICAN trial
Intrathoracic <i>versus</i> cervical anastomosis after totally or hybrid minimally invasive transthoracic oesophagectomy for oesophageal cancer: cost-effectiveness analysis alongside the randomized ICAN trial Open
Background There is a worldwide trend towards minimally invasive oesophagectomy with intrathoracic anastomosis in oesophageal cancer surgery. Minimally invasive oesophagectomy with intrathoracic anastomosis has been shown to result in fewe…
View article: Implementation of a surgical ward innovation: Telemonitoring controlled by healthdot [SWITCH-trial PROTOCOL]
Implementation of a surgical ward innovation: Telemonitoring controlled by healthdot [SWITCH-trial PROTOCOL] Open
Background Monitoring patients’ vital signs is important to detect abnormalities that may indicate a disturbed postoperative course. However, manual monitoring or so-called spot checks performed by nursing staff require a significant amoun…
View article: Predicting postoperative pancreatic fistula after robotic pancreatoduodenectomy using International Study Group on Pancreatic Surgery and fistula risk scores: European multicentre retrospective cohort study
Predicting postoperative pancreatic fistula after robotic pancreatoduodenectomy using International Study Group on Pancreatic Surgery and fistula risk scores: European multicentre retrospective cohort study Open
Background Postoperative pancreatic fistula represents the leading cause of morbidity and mortality after robotic pancreatoduodenectomy. Various scores have been proposed to stratify patients based on their postoperative pancreatic fistula…
View article: Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple resection (SPARROW): a study protocol for a multicentre, open-label, randomised controlled trial
Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple resection (SPARROW): a study protocol for a multicentre, open-label, randomised controlled trial Open
ClinicalTrials.gov NCT0578431. Registered on March 23, 2023.
View article: Video-assessment of Surgical Performance in Robotic Gastro-enterostomy During Pancreatoduodenectomy
Video-assessment of Surgical Performance in Robotic Gastro-enterostomy During Pancreatoduodenectomy Open
Objective: The aim of this study is to identify learning curves for robotic gastro-enterostomy (RGE) during RPD and the predictive value of the objective structured assessment of technical skills (OSATS) score for DGE according to the Birk…
View article: Computer-Aided Decision Support and 3D Models in Pancreatic Cancer Surgery: A Pilot Study
Computer-Aided Decision Support and 3D Models in Pancreatic Cancer Surgery: A Pilot Study Open
Background: Preoperative planning of patients diagnosed with pancreatic head cancer is difficult and requires specific expertise. This pilot study assesses the added value of three-dimensional (3D) patient models and computer-aided detecti…
View article: The prognostic value of peritoneal metastases in patients with gastric cancer: a nationwide population-based study
The prognostic value of peritoneal metastases in patients with gastric cancer: a nationwide population-based study Open
None.
View article: Minimally Invasive Versus Open Left Pancreatectomy for Resectable Pancreatic Cancer: Long-Term Results of the Randomized DIPLOMA Trial
Minimally Invasive Versus Open Left Pancreatectomy for Resectable Pancreatic Cancer: Long-Term Results of the Randomized DIPLOMA Trial Open
View article: Routine Imaging or Symptomatic Follow-Up After Resection of Pancreatic Adenocarcinoma
Routine Imaging or Symptomatic Follow-Up After Resection of Pancreatic Adenocarcinoma Open
Importance International guidelines lack consistency in their recommendations regarding routine imaging in the follow-up after pancreatic resection for pancreatic ductal adenocarcinoma (PDAC). Consequently, follow-up strategies differ betw…
View article: Paravertebral Versus EPidural Analgesia in Minimally Invasive Esophageal ResectioN (PEPMEN)
Paravertebral Versus EPidural Analgesia in Minimally Invasive Esophageal ResectioN (PEPMEN) Open
Objective: To compare the quality of recovery in patients receiving epidural or paravertebral analgesia for minimally invasive esophagectomy (MIE). Background: Paravertebral analgesia may be a promising alternative to epidural analgesia, a…
View article: Omentum preservation versus complete omentectomy in gastrectomy for gastric cancer (OMEGA trial): study protocol for a randomized controlled trial
Omentum preservation versus complete omentectomy in gastrectomy for gastric cancer (OMEGA trial): study protocol for a randomized controlled trial Open
View article: 796. P02.05 NEOADJUVANT CHEMORADIOTHERAPY FOLLOWED BY ACTIVE SURVEILLANCE VERSUS STANDARD SURGERY FOR OESOPHAGEAL CANCER (SANO-TRIAL): A MULTICENTRE STEPPED-WEDGE CLUSTER-RANDOMISED NONINFERIORITY TRIAL
796. P02.05 NEOADJUVANT CHEMORADIOTHERAPY FOLLOWED BY ACTIVE SURVEILLANCE VERSUS STANDARD SURGERY FOR OESOPHAGEAL CANCER (SANO-TRIAL): A MULTICENTRE STEPPED-WEDGE CLUSTER-RANDOMISED NONINFERIORITY TRIAL Open
Background One of the standard treatments for patients with locally advanced oesophageal cancer is neoadjuvant chemoradiotherapy followed by oesophagectomy. Of these patients, 29% have a pathologically complete response. Active surveillanc…
View article: 785. MANAGEMENT OF ESOPHAGEAL CANCER WITH CONCURRENT CERVICAL NODE METASTASIS: A NATIONWIDE POPULATION-BASED COHORT STUDY
785. MANAGEMENT OF ESOPHAGEAL CANCER WITH CONCURRENT CERVICAL NODE METASTASIS: A NATIONWIDE POPULATION-BASED COHORT STUDY Open
Background In the Netherlands, the standard treatment of locally advanced, resectable esophageal cancer without metastasis is neoadjuvant chemoradiotherapy followed by esophagectomy. There is a small subset of patients that present with co…
View article: 759. P02.04 PARAVERTEBRAL VERSUS EPIDURAL ANALGESIA IN MINIMALLY INVASIVE ESOPHAGEAL RESECTION (PEPMEN): A RANDOMIZED CONTROLLED MULTICENTER TRIAL
759. P02.04 PARAVERTEBRAL VERSUS EPIDURAL ANALGESIA IN MINIMALLY INVASIVE ESOPHAGEAL RESECTION (PEPMEN): A RANDOMIZED CONTROLLED MULTICENTER TRIAL Open
Background Thoracic epidural analgesia has been the mainstay for pain control in esophageal cancer patients undergoing minimally invasive esophagectomy (MIE). Although effective epidural analgesia potentially contributes to achieving enhan…
View article: The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial
The value of splenectomy during left-sided pancreatectomy for pancreatic ductal adenocarcinoma: predefined subanalysis in the DIPLOMA randomized trial Open
no abstract available
View article: Electrical vagus nerve stimulation is a promising approach to reducing pulmonary complications after an esophagectomy: an experimental rodent model
Electrical vagus nerve stimulation is a promising approach to reducing pulmonary complications after an esophagectomy: an experimental rodent model Open
After esophagectomy, an imbalanced inflammatory response increases the risk of postoperative morbidity. The vagus nerve modulates local and systemic inflammatory responses, but its pulmonary branches are transected during esophagectomy as …
View article: Improved Pancreatic Cancer Detection and Localization on CT Scans: A Computer-Aided Detection Model Utilizing Secondary Features
Improved Pancreatic Cancer Detection and Localization on CT Scans: A Computer-Aided Detection Model Utilizing Secondary Features Open
The early detection of pancreatic ductal adenocarcinoma (PDAC) is essential for optimal treatment of pancreatic cancer patients. We propose a tumor detection framework to improve the detection of pancreatic head tumors on CT scans. In this…