Misi He
YOU?
Author Swipe
View article: Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy: a retrospective study
Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy: a retrospective study Open
Elevated SCC antigen levels, advanced tumor stage, and RD size ≥ 1.1 cm were linked to worse PFS and OS. Furthermore, the ADCmean was not a reliable predictor of survival outcomes.
View article: Risk factors associated with overall survival in patients with cervical cancer: a prospective cohort study in Western China comparing random survival forest and Cox proportional hazards models
Risk factors associated with overall survival in patients with cervical cancer: a prospective cohort study in Western China comparing random survival forest and Cox proportional hazards models Open
The RSF model demonstrated excellent discrimination, calibrated predictions, and stratified risk for CCa patients. Furthermore, it outperformed the Cox model in predicting risks, thus enabling the delivery of personalised treatment and fol…
View article: An Organoid - Guided Platform for Ovarian Cancer: Enabling Prediction of Patients' Chemotherapy Response
An Organoid - Guided Platform for Ovarian Cancer: Enabling Prediction of Patients' Chemotherapy Response Open
Background Organoids represent a new platform for drug screening and personalized medicine. However, the difficulty of organoid construction limits their wide application. Methods We collected 153 tumour samples from patients with epitheli…
View article: Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy
Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy Open
Objective To investigate the prognostic value of magnetic resonance imaging (MRI) and clinical features in locally advanced cervical cancer (LACC) after concurrent chemoradiotherapy (CCRT). Method This study recruited 189 patients with LAC…
View article: Super-enhancer–driven EFNA1 fuels tumor progression in cervical cancer via the FOSL2-Src/AKT/STAT3 axis
Super-enhancer–driven EFNA1 fuels tumor progression in cervical cancer via the FOSL2-Src/AKT/STAT3 axis Open
Super-enhancers (SEs) are expansive cis-regulatory elements known for amplifying oncogene expression across various cancers. However, their role in cervical cancer (CC), a remarkable global malignancy affecting women, remains underexplored…
View article: Predictors of para-aortic lymph node metastasis based on pathological diagnosis via surgical staging in patients with locally advanced cervical cancer: A multicenter study
Predictors of para-aortic lymph node metastasis based on pathological diagnosis via surgical staging in patients with locally advanced cervical cancer: A multicenter study Open
Para-aortic lymph node (PALN) metastasis of patients with locally advanced cervical cancer (LACC) is associated with multiple risk factors. This study aimed to identify risk factors and develop a predictive model for PALN metastasis based …
View article: Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines
Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines Open
Human papillomavirus (HPV) is a major global health issue and is recognized as the leading cause of cervical cancer. While prophylactic vaccination programs have led to substantial reductions in both HPV infection rates and cervical cancer…
View article: Fatal risk in hysteroscopic surgery that should not be overlooked: Uterine artery pseudoaneurysm
Fatal risk in hysteroscopic surgery that should not be overlooked: Uterine artery pseudoaneurysm Open
This article provides a detailed account of the diagnosis and treatment of a case involving a uterine artery pseudoaneurysm (UAP), as well as an analysis of UAP etiology. This finding emphasizes that UAP should be considered in patients pr…
View article: Genetic analysis of cervical cancer with lymph node metastasis
Genetic analysis of cervical cancer with lymph node metastasis Open
The somatic SNV/Indels of EP300 and FBXW7, SBS3 homologous recombination-mediated DNA repair defect were enriched in lymph node-positive patients. For lymph node-positive patients, EP300 or FBXW7 mutations predicted poor prognosis. No matt…
View article: EP334/#226 Bevacizumab combined with chemotherapy is superior to chemotherapy in ovarian cancer after PARPi: evidence from a retrospective analysis
EP334/#226 Bevacizumab combined with chemotherapy is superior to chemotherapy in ovarian cancer after PARPi: evidence from a retrospective analysis Open
Introduction With the increasing use of PARPi, clinical cases of PARPi resistance and recurrence among OC patients have become more common. Traditional chemotherapy has proven effective in cases of OC recurrence after PARPi treatment. Howe…
View article: EP104/#212 A retrospective study comparing weekly versus tri-weekly cisplatin plus paclitaxel chemotherapy concomitant with radiotherapy in the treatment of locally advanced cervical cancer
EP104/#212 A retrospective study comparing weekly versus tri-weekly cisplatin plus paclitaxel chemotherapy concomitant with radiotherapy in the treatment of locally advanced cervical cancer Open
Introduction To assess the tumor response following definitive concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC) using magnetic resonance imaging before and after treatment. The prognosis and side effects of C…
View article: EP102/#351 Survey of the translational dysregulation in cervical cancer initiation and progression with ribosome profiling
EP102/#351 Survey of the translational dysregulation in cervical cancer initiation and progression with ribosome profiling Open
Introduction As a critical position of the multilevel gene expression regulation program, translational regulation has been found to be widely involved in cancer initiation and progression. Cervical cancer is the second largest female mali…
View article: Zinc finger and SCAN domain containing 1, ZSCAN1, is a novel stemness-related tumor suppressor and transcriptional repressor in breast cancer targeting TAZ
Zinc finger and SCAN domain containing 1, ZSCAN1, is a novel stemness-related tumor suppressor and transcriptional repressor in breast cancer targeting TAZ Open
Introduction Cancer stem cells (CSCs) targeted therapy holds the potential for improving cancer management; identification of stemness-related genes in CSCs is necessary for its development. Methods The Cancer Genome Atlas (TCGA) and the M…
View article: Efficacy of lymph node dissection on stage IIICr of cervical cancer before CCRT: study protocol for a phase III, randomized controlled clinical trial (CQGOG0103)
Efficacy of lymph node dissection on stage IIICr of cervical cancer before CCRT: study protocol for a phase III, randomized controlled clinical trial (CQGOG0103) Open
ClinicalTrials.gov Identifier: NCT04555226.
View article: Validation of the 2018 FIGO Staging System for Predicting the Prognosis of Patients With Stage IIIC Cervical Cancer
Validation of the 2018 FIGO Staging System for Predicting the Prognosis of Patients With Stage IIIC Cervical Cancer Open
Background: Risk stratification of patients with cervical cancer accompanied by positive lymph nodes (stage IIIC) (the 2018 International Federation of Gynecology and Obstetrics [FIGO] new staging system) yields a clinically heterogeneous …
View article: HPV and radiosensitivity of cervical cancer: a narrative review
HPV and radiosensitivity of cervical cancer: a narrative review Open
The radiosensitivity was significantly increased in patients with HPV+ CC, compared to HPV- patients. HPV improves the radiotherapy sensitivity of cervical cancer through a number of pathways. Meanwhile, the relationship between HPV and ra…
View article: TP041/#1460 The culture of advanced or recurrent ovarian cancer organoids and drug screening
TP041/#1460 The culture of advanced or recurrent ovarian cancer organoids and drug screening Open
Objectives Ovarian cancer (OC) is a highly heterogeneous disease usually diagnosed at advanced stage. Although most patients with advanced disease respond well to initial treatment, the majority develop recurrent disease, become resistant …
View article: TP009/#1444 Compare surgical staging with imaging in locally advanced cervical cancer: a multicenter, phase III trial
TP009/#1444 Compare surgical staging with imaging in locally advanced cervical cancer: a multicenter, phase III trial Open
Objectives Determining para-aortic lymph node (PALN) status is the most important prognostic factor and a key point for the therapeutic strategy in locally advanced cervical cancer (LACC). When positive PALN is diagnosis, radiotherapy is e…
View article: EPV191/#327 Drug screening of patient-derived organoids from ovarian cancer culture to personalized therapy, an exploratory research
EPV191/#327 Drug screening of patient-derived organoids from ovarian cancer culture to personalized therapy, an exploratory research Open
Objectives Organoids are a 3D culture model that can provide the precise genetic information and phenotype, as well as the heterogeneity of the tumor, thus provide powerful tools to model human diseases. The study (CQGOG0201) is an explora…
View article: Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: <i>in vitro</i> model using cancer stem cell enriched ovarian cancer spheroids
Re-purposing of curcumin as an anti-metastatic agent for the treatment of epithelial ovarian cancer: <i>in vitro</i> model using cancer stem cell enriched ovarian cancer spheroids Open
Malignant epithelial ovarian cancer (EOC) spheroids high frequently are detected in the malignant ascites of the patients with the extensive peritoneal metastasis of ovarian cancer, which represent a significant obstacle to efficacious tre…
View article: Adenovirus-mediated siRNA targeting CXCR2 attenuates titanium particle-induced osteolysis by suppressing osteoclast formation
Adenovirus-mediated siRNA targeting CXCR2 attenuates titanium particle-induced osteolysis by suppressing osteoclast formation Open
BACKGROUND Wear particle-induced peri-implant loosening is the most common complication affecting long-term outcomes in patients who undergo total joint arthroplasty. Wear particles and by-products from joint replacements may cause chronic…