Explanipedia

Lung function and skin fibrosis changes as predictors of survival in SSc-associated interstitial lung disease: a EUSTAR study Open

Vincent Sobanski, Jeska de Vries‐Bouwstra, Anna‐Maria Hoffmann‐Vold, Dörte Huscher, Margarida Alves , et al. · 2025

Objectives This study assessed how changes in lung function, skin fibrosis and digital ulceration (DU) burden predict mortality in patients with SSc-associated interstitial lung disease (SSc-ILD), the leading cause of death in SSc. Methods…

POS0581 INTERSTITIAL LUNG DISEASE IN ANTI-U1RNP SYSTEMIC SCLEROSIS PATIENTS: UPDATED RESULTS FROM THE EUROPEAN SCLERODERMA TRIALS AND RESEARCH (EUSTAR) DATABASE Open

Gonçalo Boleto, C. Campochiaro, O. Distler, A. Bălănescu, D. Launay , et al. · 2025

ABS0882 FREQUENCY OF SPONTANEOUS REPORTS OF MAJOR ADVERSE CARDIOVASCULAR EVENTS AND VENOUS THROMBOEMBOLISM IN PATIENTS ON JAK INHIBITORS COMPARED TO ADALIMUMAB Open

Mirna Reihl Crnogaj, Ivan Padjen, Branimir Anić · 2025

ABS0747 ROLE OF ACE GENE POLYMORPHISMS IN SYSTEMIC SCLEROSIS-ASSOCIATED PERIPHERAL VASCULOPATHY AND SKIN CHANGES Open

Boris Karanović, Marko Barešić, Ana Merkler, Branimir Anić · 2025

Autologous hematopoietic stem-cell transplantation in diffuse cutaneous systemic sclerosis: a single-center experience Open

Marko Barešić, Ljiljana Smiljanić, Igor Aurer, Mislav Cerovec, Branimir Anić · 2025

Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by multisystem involvement. Patients can be stratified into an indolent or rapidly progressive disease course. A progressive course warrants early and more aggressive …

The effect of hydroxychloroquine on activities of daily living and hand function in systemic sclerosis: results from an analysis of the EUSTAR cohort Open

Silvia Bellando-Randone, Holly Wilhalme, C. Bruni, László Czirják, O. Distler , et al. · 2025

Interstitial lung disease in anti-U1RNP systemic sclerosis patients: A European Scleroderma Trials and Research analysis Open

Gonçalo Boleto, Corrado Campochiaro, Oliver Distler, Andra Bălănescu, David Launay , et al. · 2025

Background: Interstitial lung disease is the leading cause of morbidity and mortality in systemic sclerosis, but it is characterized by significant heterogeneity in patient outcomes. So far, little is known about the influence of anti-U1RN…

Does regression of skin thickening predict improvement of internal organ involvement and survival in patients with diffuse cutaneous systemic sclerosis? A EUSTAR analysis Open

Annika Wyss, Suzana Jordan, Nicole Graf, Patrícia Carreira, Jörg H. W. Distler , et al. · 2024

We found that regression of skin fibrosis is associated with a lower probability of lung progression and better survival at follow up. The link between the disease course of skin and lung fibrosis in SSc can help to better stratify patient…

Critically Ill Patients with Newly Diagnosed Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: Case Series and Literature Review Open

Krešimir Rukavina, Ozrenka Zlopaša, Ivana Vuković Lela, Feđa Džubur, Branimir Anić , et al. · 2024

ANCA-associated vasculitides (AAVs) are rare diseases with a prevalence of less than 200 cases per million persons and an incidence of less than 25 cases per million person-years. Their presenting features can vary from prodromal and nonsp…

Preventive effects of early immunosuppressive treatment on the development of interstitial lung disease in systemic sclerosis Open

Arthiha Velauthapillai, Merle F. R. Bootsma, Cosimo Bruni, Christina Bergmann, Marco Matucci‐Cerinic , et al. · 2024

Background Hypothesizing that early treatment yields improved prognosis, we aimed to investigate how the timing of immunosuppressive treatment relates to interstitial lung disease (ILD) development and the course of pulmonary function in s…

#2963 Light chain deposition in the kidney is more frequent in patients with proliferative lupus nephritis Open

Tamara Knežević, Vanja Ivković, Ivan Padjen, Mario Laganović, Zrinka Biloglav , et al. · 2024

Background and Aims Light chain deposition in the kidney is an important histologic feature having a significant role in the pathogenesis of glomerular and autoimmune diseases, including lupus nephritis (LN). However, there is no study exa…

P78 Thrombotic thrombocytopenic purpura (TTP) in an SLE patient successfully treated with plasma exchange, caplacizumab and rituximab Open

Ivan Padjen, Marija Bakula, Branimir Anić · 2024

Objective Our aim was to present our first experience with the use of caplacizumab, an anti-von Willebrand factor monoclonal antibody, in an SLE patient who developed TTP. Data on the use of caplacizumab in SLE-associated TTP are scarce. M…

P81 Light chain deposition in the kidneys of patients with lupus nephritis Open

Tamara Knežević, Vanja Ivković, Ivan Padjen, Mario Laganović, Zrinka Biloglav , et al. · 2024

Objective Light chain deposition has been shown to be an important histologic hallmark with differences in isotype, characteristics and ratio of kappa and lambda light chains having a significant role in pathobiology, pathogenesis and prog…

Mimics of hereditary angioedema Open

Marko Barešić, Boris Karanović, Ljiljana Smiljanić, Branimir Anić · 2024

Nasljedni (hereditarni) angioedem je bolest karakterizirana periodičnim, nepredvidivim oticanjima mekih tkiva različitih lokalizacija i intenziteta s najčešće samoograničavajućim tijekom trajanja, te je u pravilu posredovan bradikininom. B…

Two sisters with one disease: Giant cell arteritis within one family Open

Marko Barešić, Lucija Šimunić, Goran Šukara, Miroslav Mayer, Branimir Anić · 2023

Giant cell arteritis (GCA) is the most common of the vasculitides, with the incidence varying from 21.57 in Scandinavia to 7.26 per 100,000 in the rest of Europe. GCA follows a polygenic inheritance pattern and rare familiar clustering.[1-…

Klonalna proliferacija T-limfocita u bolesnika sa sindromom ektodermalne displazije i imunodeficijencijom Open

Katarina Buneta, Ivan Padjen, Barbara Dreta, Branimir Anić · 2023

Cutaneous Manifestations, Clinical Characteristics, and Prognosis of Patients With Systemic Sclerosis Sine Scleroderma Open

Alain Lescoat, Suiyuan Huang, Patrícia Carreira, Elise Siegert, Jeska de Vries‐Bouwstra , et al. · 2023

Importance Systemic sclerosis (SSc) sine scleroderma (ssSSc) is a subset of SSc defined by the absence of skin fibrosis. Little is known about the natural history and skin manifestations among patients with ssSSc. Objective To characterize…

AB0823 A BAYESIAN APPROACH TO DETERMINE THE ROLE OF ORAL ANTICOAGULANTS FOR THE OCCURRENCE OF DIGITAL ULCERS IN SYSTEMIC SCLEROSIS – A EUSTAR OBSERVATIONAL STUDY Open

Alexandru Garaiman, Cathérine Gebhard, Carina Mihai, Rucsandra Dobrotă, Cosimo Bruni , et al. · 2023

AB0974 TREATMENT OF AXIAL SPONDYLOARTHRITIS WITH SECUKINUMAB: A REAL-LIFE RETROSPECTIVE COHORT STUDY Open

Ljiljana Smiljanić, Ivan Padjen, Marianne M. Martinic, Miroslav Mayer, Branimir Anić · 2023

#6899 MICROVASCULAR LESIONS IN LUPUS NEPHRITIS Open

Tamara Knežević, Ivan Padjen, Vanja Ivković, Mario Laganović, Stela Bulimbašić , et al. · 2023

Background and Aims Microvascular lesions (MVL) can be found in the kidneys of lupus nephritis (LN) patients and might be associated with worse outcomes. There are very few studies which evaluated MVLs in these patients and we aimed to pro…

Diagnosis and classification criteria of Sjögren’s syndrome Open

Branimir Anić, Miroslav Mayer, Rad Pregledni · 2023

sjögren's syndrome (ss) is a chronic, systemic autoimmune disease of unknown aetiology that manifests with various clinical manifestations.it is characterized by dense lymphocytic infiltration of exocrine glands which leads to functional i…

Rescue treatment of severe lupus myocarditis and proliferative lupus nephritis with immunoadsorption Open

Sandra Karanović, Ivan Padjen, Nikolina Bašić‐Jukić, Jadranka Šeparović Hanževački, Branimir Anić · 2023

Long-term prophylaxis of hereditary angioedema Open

Dijana Perković, Marko Barešić, Melanija Ražov Radas, Irena Ivković‐Jureković, Srđan Novak , et al. · 2022

Hereditary angioedema (HAE) is a rare inherited disease characterized by recurrent attacks of painful swelling of the subcutaneous and submucosal tissues. Recurrent attacks of angioedema lead to functional impairment, reduced quality of li…

Delphi-Based Consensus on Interstitial Lung Disease Screening in Patients with Connective Tissue Diseases (Croatian National-Based Study) Open

Mislav Radić, Srđan Novak, Marko Barešić, Ana Hečimović, Dijana Perković , et al. · 2022

The aim of this study was to develop a Croatian Delphi-based expert consensus for screening interstitial lung disease (ILD) associated with connective tissue disease (CTD). A systematic literature review was conducted on risk factors for t…

Stratification in systemic sclerosis according to autoantibody status versus skin involvement: a study of the prospective EUSTAR cohort Open

Muriel Elhaï, Nanthara Sritharan, Marouane Boubaya, Alexandra Balbir‐Gurman, Elise Siegert , et al. · 2022

POSTERS Open

Nastasia Kifer, Stojka Fustik, Mario Šestan, Marija Jelušić, Todor Arsov , et al. · 2022

Upalna bolest crijeva s vrlo ranim početkom (VEO-IBD) predstavlja skupinu upalnih bolesti crijeva (IBD) koje se javljaju prije 6. godine života.Iako genetika ima ulogu u IBD-u bilo koje dobi, monogenska etiologija

Cohort Enrichment Strategies for Progressive Interstitial Lung Disease in Systemic Sclerosis From European Scleroderma Trials and Research Open

Anna‐Maria Hoffmann‐Vold, Cathrine Brunborg, Paolo Airó, L. P. Ananyeva, László Czirják , et al. · 2022

Systemic sclerosis-associated interstitial lung disease in the EUSTAR database: analysis by region Open

Alain Lescoat, Dörte Huscher, Nils Schoof, Paolo Airó, Jeska de Vries‐Bouwstra , et al. · 2022

Objectives The prevalence and characteristics of SSc-associated interstitial lung disease (SSc-ILD) vary between geographical regions worldwide. The objectives of this study were to explore the differences in terms of prevalence, phenotype…

Glucocorticoids prescribing practices in systemic sclerosis: an analysis of the EUSTAR database Open

Michele Iudici, Denis Mongin, Elise Siegert, Patrícia Carreira, Jörg H. W. Distler , et al. · 2022

Objectives To estimate the prevalence of long-term exposure to glucocorticoids (GCs) and to identify factors associated with, and variations in prescribing practices over time and across recruiting countries. Methods We included patients w…

Use of platelet inhibitors for digital ulcers related to systemic sclerosis: EUSTAR study on derivation and validation of the DU-VASC model Open

Alexandru Garaiman, Klaus Steigmiller, Cathérine Gebhard, Carina Mihai, Rucsandra Dobrotă , et al. · 2022

Objective To develop and validate the prognostic prediction model DU-VASC to assist the clinicians in decision-making regarding the use of platelet inhibitors (PIs) for the management of digital ulcers in patients with systemic sclerosis. …

Branimir Anić YOU? Author Swipe