Misun Hwang
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View article: Expanding Role of Contrast-Enhanced Ultrasound and Elastography in the Evaluation of Abdominal Pathologies in Children
Expanding Role of Contrast-Enhanced Ultrasound and Elastography in the Evaluation of Abdominal Pathologies in Children Open
Contrast-enhanced ultrasound and elastography are two ultrasound technologies that are becoming increasingly popular in the evaluation of different abdominal pathologies in children. The use of these technologies has expanded the diagnosti…
View article: An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Veins
An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Veins Open
Cerebral ultrasound is the preferred technique for evaluating the infant brain, offering real-time bedside assessment without exposure to ionizing radiation. Microvascular imaging (MVI) ultrasound, an advanced Doppler technique, enables th…
View article: 120 Imaging and CSF biomarkers to optimize neurosurgical intervention for post-hemorrhagic hydrocephalus of prematurity
120 Imaging and CSF biomarkers to optimize neurosurgical intervention for post-hemorrhagic hydrocephalus of prematurity Open
Objectives/Goals: The timing of neurosurgery is highly variable for post-hemorrhagic hydrocephalus (PHH) of prematurity. We sought to utilize microvascular imaging (MVI) in ultrasound (US) to identify biomarkers to discern the opportune ti…
View article: A novel translational bioinformatics framework for facilitating multimodal data analyses in preclinical models of neurological injury
A novel translational bioinformatics framework for facilitating multimodal data analyses in preclinical models of neurological injury Open
Pediatric neurological injury and disease is a critical public health issue due to increasing rates of survival from primary injuries (e.g., cardiac arrest, traumatic brain injury) and a lack of monitoring technologies and therapeutics for…
View article: Ultrasound innovations in abdominal radiology: techniques and clinical applications in pediatric imaging
Ultrasound innovations in abdominal radiology: techniques and clinical applications in pediatric imaging Open
View article: Modified Beer-Lambert algorithm to measure pulsatile blood flow, critical closing pressure, and intracranial hypertension
Modified Beer-Lambert algorithm to measure pulsatile blood flow, critical closing pressure, and intracranial hypertension Open
We introduce a frequency-domain modified Beer-Lambert algorithm for diffuse correlation spectroscopy to non-invasively measure flow pulsatility and thus critical closing pressure (CrCP). Using the same optical measurements, CrCP was obtain…
View article: Metabolic Pathways in Hydrocephalus: Profiling with Proteomics and Advanced Imaging
Metabolic Pathways in Hydrocephalus: Profiling with Proteomics and Advanced Imaging Open
Hemorrhagic hydrocephalus is a common pathology in neonates with high mortality and morbidity. Current imaging approaches fail to capture the mechanisms behind its pathogenesis. Here, we discuss the processes underlying this pathology, the…
View article: Sedation and anesthesia for imaging of the infant and neonate—a brief review
Sedation and anesthesia for imaging of the infant and neonate—a brief review Open
View article: Pupillary Light Reflex Detected by Ophthalmic Ultrasonography in Critically Ill Children With Difficult to Assess Pupils
Pupillary Light Reflex Detected by Ophthalmic Ultrasonography in Critically Ill Children With Difficult to Assess Pupils Open
Direct visualization of the eye can be difficult or impossible when there is significant facial burns, trauma, or edema. We present 4 nonresponsive, critically ill children whose pupils could not be directly visualized. Ophthalmic ultrasou…
View article: Intravenous administration of ultrasound contrast to critically ill pediatric patients
Intravenous administration of ultrasound contrast to critically ill pediatric patients Open
View article: Sonothrombolysis: State-of-the-Art and Potential Applications in Children
Sonothrombolysis: State-of-the-Art and Potential Applications in Children Open
In recent years, advances in ultrasound therapeutics have been implemented into treatment algorithms for the adult population; however, the use of therapeutic ultrasound in the pediatric population still needs to be further elucidated. In …
View article: Improving sub-pixel accuracy in ultrasound localization microscopy using supervised and self-supervised deep learning
Improving sub-pixel accuracy in ultrasound localization microscopy using supervised and self-supervised deep learning Open
With a spatial resolution of tens of microns, ultrasound localization microscopy (ULM) reconstructs microvascular structures and measures intravascular flows by tracking microbubbles (1–5 μm) in contrast enhanced ultrasound (CEUS) images. …
View article: Cerebral Microvascular Imaging in Infants
Cerebral Microvascular Imaging in Infants Open
Brain ultrasound in infants, although widely utilized, provides limited functional insights into the brain. Although color and power Doppler ultrasounds have allowed quantitative assessment of cerebral macrovascular flow dynamics, there is…
View article: Issue Information
Issue Information Open
Sigma Theta Tau International,
View article: Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning
Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning Open
These are the original PSFs used for generating the training, validation, and evaluation dataset for the paper "Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning".
View article: Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning
Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning Open
These are the original PSFs used for generating the training, validation, and evaluation dataset for the paper "Improving Sub-pixel Accuracy in Ultrasound Localization Microscopy Using Supervised and Self-supervised Deep Learning".
View article: A Template for Translational Bioinformatics: Facilitating Multimodal Data Analyses in Preclinical Models of Neurological Injury
A Template for Translational Bioinformatics: Facilitating Multimodal Data Analyses in Preclinical Models of Neurological Injury Open
Background Pediatric neurological injury and disease is a critical public health issue due to increasing rates of survival from primary injuries (e.g., cardiac arrest, traumatic brain injury) and a lack of monitoring technologies and thera…
View article: Correction: Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children
Correction: Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children Open
temporal intensity autocorrelation curve (g 2 )" in Fig. 6 caption.
View article: Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children
Advanced Neuromonitoring Modalities on the Horizon: Detection and Management of Acute Brain Injury in Children Open
Timely detection and monitoring of acute brain injury in children is essential to mitigate causes of injury and prevent secondary insults. Increasing survival in critically ill children has emphasized the importance of neuroprotective mana…
View article: Evaluation of the Cerebrospinal Fluid Flow Dynamics with Microvascular Imaging Ultrasound in Infants
Evaluation of the Cerebrospinal Fluid Flow Dynamics with Microvascular Imaging Ultrasound in Infants Open
Purpose: Microvascular imaging ultrasound (MVI) can detect slow blood flow in small-caliber cerebral vessels. This technology may help assess flow in other intracranial structures, such as the ventricular system. In this study, we describe…
View article: Utility of Cerebral Microvascular Imaging in Infants Undergoing ECMO
Utility of Cerebral Microvascular Imaging in Infants Undergoing ECMO Open
Purpose: Infants who require extracorporeal membrane oxygenation (ECMO) therapy have an increased risk of neurological complications and mortality. Microvascular imaging (MVI) is an advanced Doppler technique that allows high-resolution vi…
View article: Quantitative Evaluation of Brain Echogenicity in Hypoxic-Ischemic Encephalopathy in Term Neonates Compared with Controls
Quantitative Evaluation of Brain Echogenicity in Hypoxic-Ischemic Encephalopathy in Term Neonates Compared with Controls Open
Purpose Neurosonography evaluation of neonatal hypoxic-ischemic encephalopathy (HIE) is mainly qualitative. We aimed to quantitatively compare the echogenicity of several brain regions in patients with HIE to healthy controls. Materials an…
View article: Transtemporal brain contrast-enhanced ultrasound in children: preliminary experience in patients without neurological disorders
Transtemporal brain contrast-enhanced ultrasound in children: preliminary experience in patients without neurological disorders Open
View article: High-resolution neurosonographic examination of the lenticulostriate vessels in neonates with hypoxic-ischemic encephalopathy
High-resolution neurosonographic examination of the lenticulostriate vessels in neonates with hypoxic-ischemic encephalopathy Open
Objective To assess the feasibility of visualizing lenticulostriate vessels (LV) using a linear high-resolution ultrasound probe and characterize LV morphology to determine whether morphological alterations in LV are present in neonatal hy…
View article: A concise guide to transtemporal contrast-enhanced ultrasound in children
A concise guide to transtemporal contrast-enhanced ultrasound in children Open
View article: Brain contrast-enhanced ultrasonography and elastography in infants
Brain contrast-enhanced ultrasonography and elastography in infants Open
Advanced ultrasound techniques, including brain contrast-enhanced ultrasonography and elastography, are increasingly being explored to better understand infant brain health. While conventional brain ultrasonography provides a convenient, n…
View article: Contrast-enhanced ultrasound of adrenal hemorrhage: a helpful problem solving tool
Contrast-enhanced ultrasound of adrenal hemorrhage: a helpful problem solving tool Open
Aims: A focal lesion in the region of the adrenal gland in a newborn often requires further assessment. Ultrasound (US) is the initial imaging method of choice in young children as it does not use radiation or require sedation and it has e…
View article: Neonatal gastrointestinal emergencies: a radiological review
Neonatal gastrointestinal emergencies: a radiological review Open
View article: Can Ultrasound-Guided Xenon Delivery Provide Neuroprotection in Traumatic Brain Injury?
Can Ultrasound-Guided Xenon Delivery Provide Neuroprotection in Traumatic Brain Injury? Open
Traumatic brain injury (TBI) is associated with high mortality and morbidity in children and adults. Unfortunately, there is no effective management for TBI in the acute setting. Rodent studies have shown that xenon, a well-known anestheti…
View article: Current understanding and future potential applications of cerebral microvascular imaging in infants
Current understanding and future potential applications of cerebral microvascular imaging in infants Open
Microvascular imaging is an advanced Doppler ultrasound technique that detects slow flow in microvessels by suppressing clutter signal and motion-related artifacts. The technique has been applied in several conditions to assess organ perfu…