Mitchell D. Cohen
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View article: Supplementary Figure S5 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion
Supplementary Figure S5 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion Open
Mutational signatures for changes seen in WTC-exposed responders above the age of 60
View article: Supplementary Table S2 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion
Supplementary Table S2 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion Open
Nonsynonymous alterations seen in WTC-exposed responders
View article: Supplementary Figure S9 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion
Supplementary Figure S9 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion Open
WTC-PM impairs hematopoietic stem cell function
View article: Supplementary Figure S7 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion
Supplementary Figure S7 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion Open
IL1RAP deletion rescues the expansion of WTC-PM-dependent Tet2 mutant cells in vivo
View article: Supplementary Figure S1 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion
Supplementary Figure S1 from Elevated Clonal Hematopoiesis in 9/11 First Responders Has Distinct Age-related Patterns and Relies on IL1RAP for Clonal Expansion Open
Prevalence of somatic mutation (VAF ≤ 35%) in WTC-exposed responders
View article: Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Differentially expressed genes in rat prostates exposed to WTC dusts
View article: Supplementary Data 1 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 1 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Difference in gene expression between archived WTC and non WTC cases
View article: Supplementary Figures from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Figures from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Supplementary Figures 1-3
View article: Supplementary Data 2 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 2 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
List of genes used in cell type enrichment analysis
View article: Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 3 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Differentially expressed genes in rat prostates exposed to WTC dusts
View article: Supplementary Data 1 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 1 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Difference in gene expression between archived WTC and non WTC cases
View article: Supplementary Figures from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Figures from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
Supplementary Figures 1-3
View article: Data from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Data from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
An excess incidence of prostate cancer has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which contained carcinogens and tumor-promoting agents, could facilitate prostate cancer de…
View article: Data from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Data from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
An excess incidence of prostate cancer has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which contained carcinogens and tumor-promoting agents, could facilitate prostate cancer de…
View article: Supplementary Data 2 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Supplementary Data 2 from Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
List of genes used in cell type enrichment analysis
View article: DNMT3A/miR-129-2-5p/Rac1 Is an Effector Pathway for SNHG1 to Drive Stem-Cell-like and Invasive Behaviors of Advanced Bladder Cancer Cells
DNMT3A/miR-129-2-5p/Rac1 Is an Effector Pathway for SNHG1 to Drive Stem-Cell-like and Invasive Behaviors of Advanced Bladder Cancer Cells Open
The stem-cell-like behavior of cancer cells plays a central role in tumor heterogeneity and invasion and correlates closely with drug resistance and unfavorable clinical outcomes. However, the molecular underpinnings of cancer cell stemnes…
View article: Longitudinal Impact of WTC Dust Inhalation on Rat Cardiac Tissue Transcriptomic Profiles
Longitudinal Impact of WTC Dust Inhalation on Rat Cardiac Tissue Transcriptomic Profiles Open
First responders (FR) exposed to the World Trade Center (WTC) Ground Zero air over the first week after the 9/11 disaster have an increased heart disease incidence compared to unexposed FR and the general population. To test if WTC dusts w…
View article: Health effects following exposure to dust from the World Trade Center disaster: An update
Health effects following exposure to dust from the World Trade Center disaster: An update Open
View article: Longitudinal impact on rat cardiac tissue transcriptomic profiles due to acute intratracheal inhalation exposures to isoflurane
Longitudinal impact on rat cardiac tissue transcriptomic profiles due to acute intratracheal inhalation exposures to isoflurane Open
Isoflurane (ISO) is a widely used inhalation anesthetic in experiments with rodents and humans during surgery. Though ISO has not been reported to impart long-lasting side effects, it is unknown if ISO can influence gene regulation in cert…
View article: lncRNA SNHG1 Promotes Basal Bladder Cancer Invasion via Interaction with PP2A Catalytic Subunit and Induction of Autophagy
lncRNA SNHG1 Promotes Basal Bladder Cancer Invasion via Interaction with PP2A Catalytic Subunit and Induction of Autophagy Open
Although basal muscle-invasive bladder cancers (MIBCs) are predominant, are more aggressive, and have bad prognoses, molecular mechanisms underlying how basal MIBC formation/progression have been barely explored. In the present study, SNHG…
View article: Impact on rats from acute intratracheal inhalation exposures to WTC dusts
Impact on rats from acute intratracheal inhalation exposures to WTC dusts Open
Background: Studies have revealed the increased incidence of health disorders in First Responders (FR) who were at Ground Zero over the initial 72 hr after the World Trade Center (WTC) collapses. Previous studies in rats exposed to …
View article: Impact on rats from acute intratracheal inhalation exposures to WTC dusts
Impact on rats from acute intratracheal inhalation exposures to WTC dusts Open
Background: Studies have revealed the increased incidence of health disorders in First Responders (FR) who were at Ground Zero over the initial 72 hr after the World Trade Center (WTC) collapses. Previous studies in rats exposed to …
View article: Overexpressed miR-200a promotes bladder cancer invasion through direct regulating Dicer/miR-16/JNK2/MMP-2 axis
Overexpressed miR-200a promotes bladder cancer invasion through direct regulating Dicer/miR-16/JNK2/MMP-2 axis Open
View article: Complementary biobank of rodent tissue samples to study the effect of World Trade Center exposure on cancer development
Complementary biobank of rodent tissue samples to study the effect of World Trade Center exposure on cancer development Open
World Trade Center (WTC) responders were exposed to mixture of dust, smoke, chemicals and carcinogens. New York University (NYU) and Mount Sinai have recreated WTC exposure in rodents to observe the resulting systemic and local biological …
View article: Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade
Prostate Cancer in World Trade Center Responders Demonstrates Evidence of an Inflammatory Cascade Open
An excess incidence of prostate cancer has been identified among World Trade Center (WTC) responders. In this study, we hypothesized that WTC dust, which contained carcinogens and tumor-promoting agents, could facilitate prostate cancer de…
View article: Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression
Isorhapontigenin (ISO) inhibits stem cell-like properties and invasion of bladder cancer cell by attenuating CD44 expression Open
View article: Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management
Health effects of World Trade Center (WTC) Dust: An unprecedented disaster with inadequate risk management Open
The World Trade Center (WTC) twin towers in New York City collapsed on 9/11/2001, converting much of the buildings' huge masses into dense dust clouds of particles that settled on the streets and within buildings throughout Lower Manhattan…