Mitchell Ferguson
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View article: Data from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Data from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cancer tissue functions as an ecosystem of a diverse set of cells that interact in a complex tumor microenvironment. Genomic tools applied to biopsies in bulk fail to account for this tumor heterogeneity, whereas single-cell imaging method…
View article: Blaesius_Manuscript_MCR_Aug26_2016_Supplemental tables and figures from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Blaesius_Manuscript_MCR_Aug26_2016_Supplemental tables and figures from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cell sorting strategy, Pathway maps for differentially expressed genes, Differentially expressed surface markers, AXL gene set used in analysis. Figure S1: Staining and gating strategy of flow cytometry analysis. Figure S2: Sorting strateg…
View article: Blaesius_Manuscript_MCR_Aug26_2016_Supplemental tables and figures from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Blaesius_Manuscript_MCR_Aug26_2016_Supplemental tables and figures from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cell sorting strategy, Pathway maps for differentially expressed genes, Differentially expressed surface markers, AXL gene set used in analysis. Figure S1: Staining and gating strategy of flow cytometry analysis. Figure S2: Sorting strateg…
View article: Data from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Data from Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cancer tissue functions as an ecosystem of a diverse set of cells that interact in a complex tumor microenvironment. Genomic tools applied to biopsies in bulk fail to account for this tumor heterogeneity, whereas single-cell imaging method…
View article: High accuracy gene expression profiling of sorted cell subpopulations from breast cancer PDX model tissue
High accuracy gene expression profiling of sorted cell subpopulations from breast cancer PDX model tissue Open
Intratumor Heterogeneity (ITH) is a functionally important property of tumor tissue and may be involved in drug resistance mechanisms. Although descriptions of ITH can be traced back to very early reports about cancer tissue, mechanistic i…
View article: Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cancer tissue functions as an ecosystem of a diverse set of cells that interact in a complex tumor microenvironment (TME). Genomic tools applied to biopsies in bulk fail to account for this tumor heterogeneity while single cell imaging met…
View article: Correction: Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue
Correction: Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Open
[This corrects the article DOI: 10.18632/oncotarget.26911.].
View article: Abstract 4710: Surface protein marker and single cell gene expression profiling of individual tumor cells dissociated from small cell lung cancer pdx mouse models can be correlated with<i>in vivo</i>sensitivity to the p70S6K/AKT1/3 inhibitor M2698
Abstract 4710: Surface protein marker and single cell gene expression profiling of individual tumor cells dissociated from small cell lung cancer pdx mouse models can be correlated with<i>in vivo</i>sensitivity to the p70S6K/AKT1/3 inhibitor M2698 Open
Small Cell Lung Cancer (SCLC) is characterized by rapid tumor growth and currently, there are few therapeutic options or predictive biomarkers. Patient derived xenograft (PDX) models are capable of recapitulating solid tumor growth includi…
View article: Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue
Flow based single cell analysis of the immune landscape distinguishes Barrett’s esophagus from adjacent normal tissue Open
Barrett's esophagus (BE) is metaplasia of the squamous epithelium to a specialized columnar epithelium. BE progresses through low- and high-grade dysplasia before developing into esophageal adenocarcinoma. The BE microenvironment is not we…
View article: Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue Open
Cancer tissue functions as an ecosystem of a diverse set of cells that interact in a complex tumor microenvironment. Genomic tools applied to biopsies in bulk fail to account for this tumor heterogeneity, whereas single-cell imaging method…