Mitchell R. Riley
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View article: Fast-Slow Analysis of a Model For the Stimulation of Enzymatic Activity by a Competitive Inhibitor
Fast-Slow Analysis of a Model For the Stimulation of Enzymatic Activity by a Competitive Inhibitor Open
Competitive inhibitors can, paradoxically, stimulate an enzymatic reaction at low to moderate doses. Competitive inhibition of an enzyme occurs when an inhibitor binds to the enzyme's binding site and blocks the enzyme's target molecule fr…
View article: A Type Theory with a Tiny Object
A Type Theory with a Tiny Object Open
We present an extension of Martin-Löf Type Theory that contains a tiny object; a type for which there is a right adjoint to the formation of function types as well as the expected left adjoint. We demonstrate the practicality of this type …
View article: Conway's Game of Life is Omniperiodic
Conway's Game of Life is Omniperiodic Open
In the theory of cellular automata, an oscillator is a pattern that repeats itself after a fixed number of generations; that number is called its period. A cellular automaton is called omniperiodic if there exist oscillators of all periods…
View article: Commuting Cohesions
Commuting Cohesions Open
Shulman's spatial type theory internalizes the modalities of Lawvere's axiomatic cohesion in a homotopy type theory, enabling many of the constructions from Schreiber's modal approach to differential cohomology to be carried out synthetica…
View article: Corrigendum: Patterned hippocampal stimulation facilitates memory in patients with a history of head impact and/or brain injury
Corrigendum: Patterned hippocampal stimulation facilitates memory in patients with a history of head impact and/or brain injury Open
[This corrects the article DOI: 10.3389/fnhum.2022.933401.].
View article: Patterned Hippocampal Stimulation Facilitates Memory in Patients With a History of Head Impact and/or Brain Injury
Patterned Hippocampal Stimulation Facilitates Memory in Patients With a History of Head Impact and/or Brain Injury Open
Rationale: Deep brain stimulation (DBS) of the hippocampus is proposed for enhancement of memory impaired by injury or disease. Many pre-clinical DBS paradigms can be addressed in epilepsy patients undergoing intracranial monitoring for se…
View article: Prefrontal cortical plasticity during learning of cognitive tasks
Prefrontal cortical plasticity during learning of cognitive tasks Open
Training in working memory tasks is associated with lasting changes in prefrontal cortical activity. To assess the neural activity changes induced by training, we recorded single units, multi-unit activity (MUA) and local field potentials …
View article: Training-induced prefrontal neuronal changes transfer between tasks
Training-induced prefrontal neuronal changes transfer between tasks Open
Training to improve working memory is associated with changes in prefrontal activation and confers lasting benefits, some of which generalize to untrained tasks, though the issue remains contentious and the neural substrate underlying such…
View article: Identification of images of COVID-19 from Chest Computed Tomography (CT) images using Deep learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks
Identification of images of COVID-19 from Chest Computed Tomography (CT) images using Deep learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks Open
For testing patients infected with COVID-19, along with RT-PCR testing, chest radiology images are being used. For the detection of COVID-19 from radiology images, many organizations are proposing the use of Deep Learning. University of Wa…
View article: Detection of COVID-19 from Chest X-rays using Deep Learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks
Detection of COVID-19 from Chest X-rays using Deep Learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks Open
The COVID-19 pandemic has been having a severe and catastrophic effect on humankind and is being considered the most crucial health calamity of the century. One of the best methods of detecting COVID-19 is from radiological images, namely …
View article: Identification of images of COVID-19 from Chest X-rays using Deep Learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks
Identification of images of COVID-19 from Chest X-rays using Deep Learning: Comparing COGNEX VisionPro Deep Learning 1.0 Software with Open Source Convolutional Neural Networks Open
The COVID-19 pandemic has been having a severe and catastrophic effect on humankind and is being considered the most crucial health calamity of the century. One of the best methods of detecting COVID-19 is from radiological images, namely …
View article: Working memory capacity is enhanced by distributed prefrontal activation and invariant temporal dynamics
Working memory capacity is enhanced by distributed prefrontal activation and invariant temporal dynamics Open
Significance Working memory capacity is notoriously limited to a handful of items, creating one of the central bottlenecks of human cognition, but can be improved by training. The neural basis of this improvement remains a matter of debate…
View article: Lateralization of Executive Function: Working Memory Advantage for Same Hemifield Stimuli in the Monkey
Lateralization of Executive Function: Working Memory Advantage for Same Hemifield Stimuli in the Monkey Open
Working memory capacity, the amount of information that may be maintained in mind over a period of seconds, is extremely limited, to a handful of items. Some evidence exists that the number of visual items that may be maintained in working…
View article: Plasticity of prefrontal cortical responses during learning in a working memory task
Plasticity of prefrontal cortical responses during learning in a working memory task Open
Training to improve working memory is associated with increased BOLD signal from the lateral prefrontal cortex and confers lasting cognitive benefits in humans. The neural substrate underlying these changes is poorly understood. In a previ…
View article: Functional specialization of areas along the anterior–posterior axis of the primate prefrontal cortex
Functional specialization of areas along the anterior–posterior axis of the primate prefrontal cortex Open
Functional specialization of areas along the anterior-posterior axis of the lateral prefrontal cortex has been speculated but little evidence exists about distinct neurophysiological properties between prefrontal sub-regions. To address th…
View article: Role of Prefrontal Persistent Activity in Working Memory
Role of Prefrontal Persistent Activity in Working Memory Open
The prefrontal cortex is activated during working memory, as evidenced by fMRI results in human studies and neurophysiological recordings in animal models. Persistent activity during the delay period of working memory tasks, after the offs…