Mitsuaki Ishida
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View article: Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature
Ossification in pancreatic neoplasms: A report of three cases of neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm with review of the literature Open
Heterotopic ossification (HO) is the formation of mature bone tissues in non-skeletal tissues and has been reported in various types of neoplasms. The presence of HO in pancreatic tumors is rare, with only 16 cases reported in the English …
View article: Presence of Adipophilin-Positive Cancer-Associated Fibroblasts Is an Independent Poor Prognostic Indicator and Is Correlated with Immature-Type Desmoplastic Reaction in Patients with Colorectal Cancer
Presence of Adipophilin-Positive Cancer-Associated Fibroblasts Is an Independent Poor Prognostic Indicator and Is Correlated with Immature-Type Desmoplastic Reaction in Patients with Colorectal Cancer Open
Background/Objectives: Immature-type (IM type) desmoplastic reaction (DR) is a poor prognostic indicator of CRC; however, the underlying mechanism has not yet been clarified. Recent studies have demonstrated that energy metabolism, includi…
View article: Meningeal Solitary Fibrous Tumor: A Cytological Report With Emphasis on the Usefulness of Immunocytochemical Analysis for <scp>STAT6</scp>
Meningeal Solitary Fibrous Tumor: A Cytological Report With Emphasis on the Usefulness of Immunocytochemical Analysis for <span>STAT6</span> Open
Solitary fibrous tumors (SFTs) are rare neoplasms characterized by spindle neoplastic cell proliferation within collagenous stroma and prominent dilated vasculature. They present a wide histopathological spectrum, ranging from hypocellular…
View article: Immunohistochemical Demonstration of Tuft Cells in Human Acinar-to-Ductal Metaplasia and Pancreatic Intraepithelial Neoplasia
Immunohistochemical Demonstration of Tuft Cells in Human Acinar-to-Ductal Metaplasia and Pancreatic Intraepithelial Neoplasia Open
Background/Objectives: Acinar-to-ductal metaplasia (ADM) refers to the dedifferentiation or transdifferentiation of pancreatic acinar cells. Recently, ADM has received considerable attention as a potential precursor of pancreatic tumours. …
View article: Cytological features of small cell neuroendocrine carcinoma of the uterine cervix
Cytological features of small cell neuroendocrine carcinoma of the uterine cervix Open
Small cell neuroendocrine carcinoma (SCNEC) of the cervix is rare. Cytological examination is a valuable tool for detecting cervical lesions; however, due to the rarity of cervical SCNEC, its accurate diagnosis remains challenging. In some…
View article: Relationship of Desmoplastic Reaction and Tumour Budding in Primary and Lung Metastatic Lesions of Colorectal Cancer and Their Prognostic Significance
Relationship of Desmoplastic Reaction and Tumour Budding in Primary and Lung Metastatic Lesions of Colorectal Cancer and Their Prognostic Significance Open
Background/Objectives: Histopathological indicators, including desmoplastic reaction (DR) and tumour budding (TB), are significant prognostic indicators for metastatic liver lesions in patients with colorectal cancer (CRC). However, the re…
View article: HIF-1α Promotes Luteinization via NDRG1 Induction in the Human Ovary
HIF-1α Promotes Luteinization via NDRG1 Induction in the Human Ovary Open
Background/Objectives: Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that plays a crucial role in various physiological and pathological processes of the ovary. However, the timing of HIF-1α expression and its specific bio…
View article: Cytological features of oncocytic pleomorphic adenoma of the salivary gland: Using the Milan classification system to report 3 patients
Cytological features of oncocytic pleomorphic adenoma of the salivary gland: Using the Milan classification system to report 3 patients Open
Pleomorphic adenoma (PA) is the most common salivary gland tumour. Pre-operative fine-needle aspiration (FNA) is currently one of the most widely used cytological examination techniques for the diagnosis of salivary gland tumours. Because …
View article: Metastatic Malignant Granular Cell Tumor in the Lymph Node: A Cytological Report With Immunocytochemical Analysis
Metastatic Malignant Granular Cell Tumor in the Lymph Node: A Cytological Report With Immunocytochemical Analysis Open
Granular cell tumors (GCTs) are relatively rare, whereas malignant GCTs are extremely rare. This brief report describes a cytological case of metastatic malignant GCT in the lymph node with immunocytochemical analysis. A 77 years old Japan…
View article: The Prognostic Impact of Adipophilin Expression on Long-Term Survival Following Liver Resection in Patients with Colorectal Liver Metastases
The Prognostic Impact of Adipophilin Expression on Long-Term Survival Following Liver Resection in Patients with Colorectal Liver Metastases Open
Background/Objectives: Adipophilin (ADP) is a protein associated with lipid droplets, and its expression is related to poor prognosis in certain cancers. However, its impact on the survival of patients with colorectal liver metastases (CRL…
View article: Intravascular large B‑cell lymphoma diagnosed by skin biopsy from cherry angioma: A case report
Intravascular large B‑cell lymphoma diagnosed by skin biopsy from cherry angioma: A case report Open
Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of large B-cell lymphoma characterized by the exclusive growth of lymphoma cells within blood vessels. Due to the lack of lymphadenopathy and mass formation, the diagnosis of I…
View article: Prognostic scoring system based on indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer
Prognostic scoring system based on indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer Open
View article: Cytological features of a lymphoepithelial cyst of the salivary gland with application of the second edition of Milan System for Reporting Salivary Gland Cytopathology
Cytological features of a lymphoepithelial cyst of the salivary gland with application of the second edition of Milan System for Reporting Salivary Gland Cytopathology Open
Lymphoepithelial cysts (LECs) of the salivary glands are relatively rare, benign cystic lesions. Characteristic histopathological features of LEC include presence of well-circumscribed unilocular cysts surrounded by dense lymphoid tissue w…
View article: Analysis of the clinicopathological features of tailgut cyst with emphasis on the development of neoplastic lesions
Analysis of the clinicopathological features of tailgut cyst with emphasis on the development of neoplastic lesions Open
Tailgut cyst is a rare congenital cyst occurring in the retrorectal space and development of neoplastic lesions in tailgut cyst has been reported. Due to the rarity of the tumor, the histogenesis of neoplastic lesions in tailgut cyst has r…
View article: Prognostic scoring system based on indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer
Prognostic scoring system based on indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer Open
Prognostic stratification is an urgent concern for patients with colorectal cancer (CRC). The desmoplastic reaction (DR) is speculated to mirror the tumor microenvironment. DR types are considered independent prognostic indicators in CRC, …
View article: Downregulated expression of PBRM1 in sarcomatoid hepatocellular carcinoma
Downregulated expression of PBRM1 in sarcomatoid hepatocellular carcinoma Open
Sarcomatoid hepatocellular carcinoma (SHCC) is a rare and highly lethal subtype of HCC. The present study aimed to explore the unique markers of SHCC using whole gene expression analysis. Subsequently, gene expression analysis was performe…
View article: Expression of Preferentially Expressed Antigen in Melanoma, a Cancer/Testis Antigen, in Carcinoma In Situ of the Urinary Tract
Expression of Preferentially Expressed Antigen in Melanoma, a Cancer/Testis Antigen, in Carcinoma In Situ of the Urinary Tract Open
Carcinoma in situ (CIS) of the urinary tract comprises 1–3% of all urothelial malignancies and is often a precursor to muscle-invasive urothelial carcinoma (UC). This study aimed to examine the expression profiles of preferentially express…
View article: Internal carotid bulb occlusion by a giant thrombus after thoracoscopic left upper lung lobectomy successfully treated with endovascular stenting: a case report
Internal carotid bulb occlusion by a giant thrombus after thoracoscopic left upper lung lobectomy successfully treated with endovascular stenting: a case report Open
Background Perioperative acute ischemic stroke following lung resection is relatively rare, though a devastating complication. Specifically, patients undergoing left upper lung lobectomy for lung cancer are likely to develop perioperative …
View article: EP06.06-09 Clinical Significance of the Presence of MECA-79-Positive Tumor Cells in Pathological Stage IA Invasive Adenocarcinoma of the Lung
EP06.06-09 Clinical Significance of the Presence of MECA-79-Positive Tumor Cells in Pathological Stage IA Invasive Adenocarcinoma of the Lung Open
View article: EP06.02-05 Agreement among Programmed Cell Death Ligand-1 Immunohistochemistry Results Using 73-10, 22C3 and 28-8 Antibodies for Lung Cancer
EP06.02-05 Agreement among Programmed Cell Death Ligand-1 Immunohistochemistry Results Using 73-10, 22C3 and 28-8 Antibodies for Lung Cancer Open
View article: Prognostic impact of soluble PD-L1 derived from tumor-associated macrophages in non-small-cell lung cancer
Prognostic impact of soluble PD-L1 derived from tumor-associated macrophages in non-small-cell lung cancer Open
View article: Autophagy Inhibition Increased Sensitivity of Pancreatic Cancer Cells to Carbon Ion Radiotherapy
Autophagy Inhibition Increased Sensitivity of Pancreatic Cancer Cells to Carbon Ion Radiotherapy Open
Background/Aims: Pancreatic cancer has the poorest survival rate among all cancer types. Therefore, it is essential to develop an effective treatment strategy for this cancer. Methods: We performed carbon ion radiotherapy (CIRT) in human p…
View article: Development of novel prognostic score based on the indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer
Development of novel prognostic score based on the indicators reflecting the tumor glandular differentiation and microenvironment for patients with colorectal cancer Open
Purpose: Development of prognostic stratification in patients with colorectal cancer (CRC) is an urgent concern. Desmoplastic reaction (DR) is a tissue reaction, speculated to represent the tumor microenvironment. DR types have been establ…
View article: Ocular and extraocular sebaceous carcinomas: A retrospective study with emphasis on the presence of <i>in situ</i> lesion and discussion and review of the histogenesis of extraocular sebaceous carcinoma
Ocular and extraocular sebaceous carcinomas: A retrospective study with emphasis on the presence of <i>in situ</i> lesion and discussion and review of the histogenesis of extraocular sebaceous carcinoma Open
Sebaceous carcinoma (SC) is a rare carcinoma classified as ocular or extraocular. Ocular SC is believed to arise from the meibomian glands or the glands of Zeis. However, the origin of extraocular SC is controversial because there is no ev…
View article: MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study
MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study Open
View article: Gastric hamartomatous inverted polyp: Report of three cases with a review of the endoscopic and clinicopathological features
Gastric hamartomatous inverted polyp: Report of three cases with a review of the endoscopic and clinicopathological features Open
Objectives A gastric hamartomatous inverted polyp (GHIP) is a rare submucosal tumor characterized histopathologically by a submucosal inverted proliferation of cystically dilated hyperplastic gastric glands. Only 42 GHIPs have been reporte…
View article: Additional file 6 of MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study
Additional file 6 of MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study Open
Supplementary Material 6
View article: MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study
MMP14 expression levels accurately predict the presence of extranodal extensions in oral squamous cell carcinoma: a retrospective cohort study Open
Background: Extranodal extension (ENE) is an adverse prognostic factor for oral squamous cell carcinoma (OSCC), and OSCC patients with ENE require neck dissection. In this study, we developed a novel ENE histology-based pathological predic…
View article: Significance of placental CD200 expression in patients with preeclampsia: Comparison between early‑ and late‑onset patients
Significance of placental CD200 expression in patients with preeclampsia: Comparison between early‑ and late‑onset patients Open
Preeclampsia, characterized by high blood pressure and proteinuria during pregnancy, causes serious complications in both the mother and the fetus. Although there have been several studies on the causes of preeclampsia, the detailed mechan…
View article: Significance of desmoplastic reactions on tumor deposits in patients with colorectal cancer
Significance of desmoplastic reactions on tumor deposits in patients with colorectal cancer Open
It has been well recognized that the tumor microenvironment serves important roles in the progression and invasion of cancer. The desmoplastic reaction (DR) is a fibrous tissue reaction around tumor cells, and the prognostic significance o…