Mitsunaga Iwata
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View article: Rebound Hyperkalemia After Potassium Repletion in Thyrotoxic Periodic Paralysis: A Case Report and Review of Management Implications
Rebound Hyperkalemia After Potassium Repletion in Thyrotoxic Periodic Paralysis: A Case Report and Review of Management Implications Open
Thyrotoxic periodic paralysis (TPP) is a potentially life-threatening complication of hyperthyroidism. It is characterized by hypokalemia-induced muscle weakness that typically begins in the proximal lower limbs and may progress to paralys…
View article: Comparative effectiveness of the use of game design elements to promote advance care planning: A protocol for systematic review and meta-analysis
Comparative effectiveness of the use of game design elements to promote advance care planning: A protocol for systematic review and meta-analysis Open
Background: Advance care planning (ACP) can positively affect patients, families, and healthcare providers. However, challenges exist regarding its wider dissemination and implementation. The use of decision aids that incorporate game desi…
View article: Clinical and molecular landscape of prolonged SARS-CoV-2 infection with resistance to remdesivir in immunocompromised patients
Clinical and molecular landscape of prolonged SARS-CoV-2 infection with resistance to remdesivir in immunocompromised patients Open
Patients with hematologic diseases have experienced coronavirus disease 2019 (COVID-19) with a prolonged, progressive course. Here, we present clinical, pathological, and virological analyses of three cases of prolonged COVID-19 among pati…
View article: Validating the <scp>DIVERT</scp> scales, <scp>CARS</scp>, and <scp>EARLI</scp> for predicting emergency department visits in home health care in Japan: A retrospective cohort study
Validating the <span>DIVERT</span> scales, <span>CARS</span>, and <span>EARLI</span> for predicting emergency department visits in home health care in Japan: A retrospective cohort study Open
Background The Detection of Indicators and Vulnerabilities for Emergency Room Trips (DIVERT) scale, the Community Assessment Risk Screen (CARS), and the Emergency Admission Risk Likelihood Index (EARLI) are scales that assess the risk of e…
View article: Internal Jugular Vein Thrombosis as the Initial Presentation of Antiphospholipid Antibody-Positive Vascular Behçet Disease: A Clinical Image
Internal Jugular Vein Thrombosis as the Initial Presentation of Antiphospholipid Antibody-Positive Vascular Behçet Disease: A Clinical Image Open
Internal jugular vein (IJV) thrombosis is a rare and potentially life-threatening condition commonly caused by central venous catheter insertion, malignant tumors, and neck infections. A 45-year-old woman with an unremarkable medical histo…
View article: Validating the DIVERT Scales, CARS, and EARLI for Predicting Emergency Department Visits in Home Health Care in Japan: a retrospective cohort study
Validating the DIVERT Scales, CARS, and EARLI for Predicting Emergency Department Visits in Home Health Care in Japan: a retrospective cohort study Open
Background The Detection of Indicators and Vulnerabilities for Emergency Room Trips (DIVERT） scale, the Community Assessment Risk Screen (CARS), and the Emergency Admission Risk Likelihood Index (EARLI) are scales that assess the risk of e…
View article: External validation and update of the International Medical Prevention Registry on Venous Thromboembolism bleeding risk score for predicting bleeding in acutely ill hospitalized medical patients: a retrospective single-center cohort study in Japan
External validation and update of the International Medical Prevention Registry on Venous Thromboembolism bleeding risk score for predicting bleeding in acutely ill hospitalized medical patients: a retrospective single-center cohort study in Japan Open
Background The International Medical Prevention Registry for Venous Thromboembolism (IMPROVE) Bleeding Risk Score is the recommended risk assessment model (RAM) for predicting bleeding risk in acutely ill medical inpatients in Western coun…
View article: COVID-19 UPDATE-Latest information, Emergency situation and Post-COVID-19 conditions-
COVID-19 UPDATE-Latest information, Emergency situation and Post-COVID-19 conditions- Open
View article: Polypharmacy of Older Surgical Patients With Extremity Fractures
Polypharmacy of Older Surgical Patients With Extremity Fractures Open
Introduction Fractures are often caused by falls in older people. Among various causes of falls, polypharmacy is known to be a risk of falls. Furthermore, potentially inappropriate medicines (PIMs), which interact with polypharmacy, includ…
View article: Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: a prospective, exploratory observational study
Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: a prospective, exploratory observational study Open
View article: Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: A prospective, exploratory observational study
Association between intrarenal venous flow from Doppler ultrasonography and acute kidney injury in patients with sepsis in critical care: A prospective, exploratory observational study Open
Background: Intrarenal venous flow (IRVF) patterns assessed using Doppler renal ultrasonography are real-time bedside visualizations of renal vein hemodynamics. Although this technique has the potential to detect renal congestion during se…
View article: External Validation of the Padua and IMPROVE-VTE Risk Assessment Models for Predicting Venous Thromboembolism in Hospitalized Adult Medical Patients: A Retrospective Single-Center Study in Japan
External Validation of the Padua and IMPROVE-VTE Risk Assessment Models for Predicting Venous Thromboembolism in Hospitalized Adult Medical Patients: A Retrospective Single-Center Study in Japan Open
Objectives: To assess the external validity of the Padua and International Medical Prevention Registry on Venous Thromboembolism (IMPROVE-VTE) risk assessment models (RAMs) for predicting venous thromboembolism (VTE) within 90 days …
View article: Radiographic and endoscopic screening to reduce gastric cancer mortality: a systematic review and meta-analysis
Radiographic and endoscopic screening to reduce gastric cancer mortality: a systematic review and meta-analysis Open
National Cancer Center Japan; and Japan Agency for Medical Research and Development.
View article: Post-discharge clinical, laboratory and radiographic features of coronavirus disease 2019 (COVID-19) patients at university hospitals in Japan.
Post-discharge clinical, laboratory and radiographic features of coronavirus disease 2019 (COVID-19) patients at university hospitals in Japan. Open
Shortness of breath, abnormal liver function test results and chest CT images often persisted for at least one month after discharge, even when symptoms were mild or moderate during hospitalization.
View article: A case of multiple trauma complicated with bilateral adrenal hemorrhage causing refractory hypotension
A case of multiple trauma complicated with bilateral adrenal hemorrhage causing refractory hypotension Open
View article: Association of Repeated Blood Cultures With Mortality in Adult Patients With Gram-Negative Bacilli Bacteremia: A Systematic Review and Meta-analysis
Association of Repeated Blood Cultures With Mortality in Adult Patients With Gram-Negative Bacilli Bacteremia: A Systematic Review and Meta-analysis Open
Background Performing repeat blood cultures after an initial positive culture (ie, follow-up blood cultures [FUBCs]) in patients with gram-negative bacilli (GNB) bacteremia is controversial. We aimed to comprehensively review the associati…
View article: Serial high-sensitivity cardiac troponin testing for the diagnosis of myocardial infarction: a scoping review
Serial high-sensitivity cardiac troponin testing for the diagnosis of myocardial infarction: a scoping review Open
Objectives We aimed to assess the diversity and practices of existing studies on several assays and algorithms for serial measurements of high-sensitivity cardiac troponin (hs-cTn) for risk stratification and the diagnosis of myocardial in…
View article: Asymptomatic entrapped denture in the hypopharynx
Asymptomatic entrapped denture in the hypopharynx Open
An early 70s asymptomatic man with cerebral infarction and dementia was brought to our emergency department for ingesting a removable partial denture. This was seen incidentally on his follow-up chest X-ray, having been diagnosed with aspi…
View article: Short-course remdesivir for healthcare-associated COVID-19: Case series from a non-acute care hospital
Short-course remdesivir for healthcare-associated COVID-19: Case series from a non-acute care hospital Open
View article: Intracranial hemorrhage caused by acute-onset severe hypernatremia
Intracranial hemorrhage caused by acute-onset severe hypernatremia Open
A 52-year-old unemployed Japanese woman with depression was brought to our emergency department (ED) after an attempted suicide. She had reportedly ingested 1500 mL of soy sauce (corresponding to 277.5 g sodium chloride) 60 min before pres…
View article: An early return-to-work program for COVID-19 close contacts in healthcare during the Omicron wave in Japan
An early return-to-work program for COVID-19 close contacts in healthcare during the Omicron wave in Japan Open
View article: An Early Return-to-Work Program for COVID-19 Close Contacts in Healthcare During the Omicron Wave in Japan
An Early Return-to-Work Program for COVID-19 Close Contacts in Healthcare During the Omicron Wave in Japan Open
During the coronavirus disease 2019 (COVID-19) pandemic, maintaining adequate staffing in healthcare facilities is important to provide a safe work environment for healthcare workers (HCWs). Japan’s early return-to-work (RTW) program may b…
View article: Emergency Surgical Management of Lumbar Burst Fracture in a Patient with COVID-19: A Case Report
Emergency Surgical Management of Lumbar Burst Fracture in a Patient with COVID-19: A Case Report Open
View article: Antibody Responses to BNT162b2 Vaccination in Japan: Monitoring Vaccine Efficacy by Measuring IgG Antibodies against the Receptor-Binding Domain of SARS-CoV-2
Antibody Responses to BNT162b2 Vaccination in Japan: Monitoring Vaccine Efficacy by Measuring IgG Antibodies against the Receptor-Binding Domain of SARS-CoV-2 Open
Mass vaccination campaigns using mRNA vaccines against SARS-CoV-2 have begun in many countries. Serological assays to detect antibody production may be a useful tool to monitor the efficacy of SARS-CoV-2 vaccination in individuals.
View article: Effectiveness of decision aids on cancer-screening decision-making: an umbrella review protocol
Effectiveness of decision aids on cancer-screening decision-making: an umbrella review protocol Open
Introduction Although systematic reviews have shown how decision aids about cancer-related clinical decisions improve selection of key options and shared decision-making, whether or not particular decision aids, defined by their specific p…
View article: Delayed Injection Site Reaction After mRNA-1273 Vaccination in Japan: A Retrospective, Cross-Sectional Study
Delayed Injection Site Reaction After mRNA-1273 Vaccination in Japan: A Retrospective, Cross-Sectional Study Open
The incidence of delayed injection site reaction after the first dose of mRNA-1273 vaccine was 12.5% among females and 1.5% among males in a cohort of primarily elderly Japanese. After the second dose, 48.4% of those who could be contacted…
View article: Efficacy and Safety of Favipiravir in Moderate COVID-19 Pneumonia Patients without Oxygen Therapy: A Randomized, Phase III Clinical Trial
Efficacy and Safety of Favipiravir in Moderate COVID-19 Pneumonia Patients without Oxygen Therapy: A Randomized, Phase III Clinical Trial Open
Clinicaltrials.jp number: JapicCTI-205238.
View article: Antibody responses to BNT162b2 vaccination in Japan: Monitoring vaccine efficacy by measuring IgG antibodies against the receptor binding domain of SARS-CoV-2
Antibody responses to BNT162b2 vaccination in Japan: Monitoring vaccine efficacy by measuring IgG antibodies against the receptor binding domain of SARS-CoV-2 Open
BACKGROUND To fight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), mass vaccination has begun in many countries. To investigate the usefulness of a serological assay to predi…
View article: Diagnostic accuracy of LAMP versus PCR over the course of SARS-CoV-2 infection
Diagnostic accuracy of LAMP versus PCR over the course of SARS-CoV-2 infection Open
View article: Asymptomatic entrapped denture in the hypopharynx
Asymptomatic entrapped denture in the hypopharynx Open
A 71-year-old asymptomatic man was brought to our emergency department for ingesting a removable partial denture. The plain cervical computed tomography showed that the denture was in the hypopharynx. Transoral retrieval of the denture, wi…