Mitsuru Mori
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View article: The Contributions of Knee Extension Strength and Hand Grip Strength to Factors Relevant to Physical Frailty: The Tanno-Sobetsu Study
The Contributions of Knee Extension Strength and Hand Grip Strength to Factors Relevant to Physical Frailty: The Tanno-Sobetsu Study Open
Sarcopenia is the core factor of frailty. This study specifically focused on lower limb muscle strength and examined muscle indices that indicate the risk of frailty or pre-frailty in older adults. The study included 327 community-dwelling…
View article: Association between Isoflavones and Colorectal Cancer Risk: A Case-Control Study in Japanese
Association between Isoflavones and Colorectal Cancer Risk: A Case-Control Study in Japanese Open
Background: Isoflavones, a component of soy-foods, may play a role in the inhibition of human colon cancer cell growth and the induction of apoptosis.However, the relationship between isoflavones and colorectal cancer risk remains unknown …
View article: Serum Soluble Fas Levels and Incidence of Liver Cancer in Nested Case–Control Study
Serum Soluble Fas Levels and Incidence of Liver Cancer in Nested Case–Control Study Open
Background: Soluble Fas (sFas) plays various roles in carcinogenesis and tumor dissemination by preventing apoptosis via binding to Fas ligand. We analyzed associations of serum sFas levels with the incidence of liver cancer in a prospecti…
View article: Walking Speed Is Better Than Hand Grip Strength as an Indicator of Early Decline in Physical Function with Age in Japanese Women Over 65: A Longitudinal Analysis of the Tanno-Sobetsu Study Using Linear Mixed-Effects Models
Walking Speed Is Better Than Hand Grip Strength as an Indicator of Early Decline in Physical Function with Age in Japanese Women Over 65: A Longitudinal Analysis of the Tanno-Sobetsu Study Using Linear Mixed-Effects Models Open
The decline in physical function with age is a major contributor to the need for long-term care. Age-related changes in hand grip strength, knee extension, and walking speed have been reported in cross-sectional studies, but longitudinal d…
View article: Association of Social Capital and Locus of Control with Perceived Health during the COVID-19 Pandemic in Japan
Association of Social Capital and Locus of Control with Perceived Health during the COVID-19 Pandemic in Japan Open
Previous studies have indicated that social capital and locus of control influence mental health. Accordingly, we investigated the effect of social capital and locus of control on perceived physical and mental health in the general Japanes…
View article: Super-additive associations between parity and education level on mortality from cardiovascular disease and other causes: the Japan Collaborative Cohort Study
Super-additive associations between parity and education level on mortality from cardiovascular disease and other causes: the Japan Collaborative Cohort Study Open
View article: Dairy products and the risk of developing prostate cancer: A large‐scale cohort study (JACC Study) in Japan
Dairy products and the risk of developing prostate cancer: A large‐scale cohort study (JACC Study) in Japan Open
Dairy products have been indicated as a risk factor for prostate cancer. However, only a few epidemiological studies have reported dairy products as being a risk factor for prostate cancer in Japan, reporting contradictory results. We ther…
View article: Insulin-Like Growth Factor 2 and Incidence of Liver Cancer in a Nested Case–Control Study
Insulin-Like Growth Factor 2 and Incidence of Liver Cancer in a Nested Case–Control Study Open
Background: Insulin-like growth factor (IGF)2 is a potent mitogen. To elucidate the relationship between IGF2 and risk of tumorigenesis, we analyzed associations between serum levels of IGF2 and incidence of liver cancer in a prospective c…
View article: Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study
Resveratrol improves motor function in patients with muscular dystrophies: an open-label, single-arm, phase IIa study Open
View article: Comparing the extent of breast cancer tumors through contrast-enhanced ultrasound vs B-mode, opposed with pathology: evergreen study
Comparing the extent of breast cancer tumors through contrast-enhanced ultrasound vs B-mode, opposed with pathology: evergreen study Open
View article: Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer Open
View article: Intake of Common Alcoholic and Non-Alcoholic Beverages and Breast Cancer Risk among Japanese Women: Findings from the Japan Collaborative Cohort Study
Intake of Common Alcoholic and Non-Alcoholic Beverages and Breast Cancer Risk among Japanese Women: Findings from the Japan Collaborative Cohort Study Open
This study investigated the association between intake of common alcoholic and non-alcoholic beverages and breast cancer risk among Japanese women. This study included 33,396 Japanese women aged 40-79 years from 24 areas in Japan from the …
View article: Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 and the Incidence of Malignant Neoplasms in a Nested Case–Control Study
Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 and the Incidence of Malignant Neoplasms in a Nested Case–Control Study Open
Insulin-like growth factor (IGF)-1 is a potent mitogen, but IGF binding protein (IGFBP)-3 inhibits IGF1. To elucidate the relationship between both IGF1 and IGFBP and the risk of tumorigenesis, the association between IGF1 and IGFBP3 serum…
View article: Intervention of pregnant smokers for smoking cessation by health professionals
Intervention of pregnant smokers for smoking cessation by health professionals Open
Objective We tried to develop smoking cessation program for pregnant smokers at an obstetric clinic. Methods We asked 10 obstetric clinics to participate in this projects from July to August, 2018. Eventually, 4 clinics responded to our re…
View article: Resveratrol Improves Muscle Weakness in Muscular Dystrophy: A Single-Centre Pilot Study
Resveratrol Improves Muscle Weakness in Muscular Dystrophy: A Single-Centre Pilot Study Open
View article: Differences in physical activity between seasons with and without snowfall among elderly individuals residing in areas that receive snowfall
Differences in physical activity between seasons with and without snowfall among elderly individuals residing in areas that receive snowfall Open
[Purpose] This study aimed to examine the influence of climatic conditions on the daily physical activities of elderly individuals by comparing the physical activity during seasons with and without snowfall. [Participants and Methods] In t…
View article: Genome-wide association meta-analysis identifies novel <i>GP2</i> gene risk variants for pancreatic cancer in the Japanese population
Genome-wide association meta-analysis identifies novel <i>GP2</i> gene risk variants for pancreatic cancer in the Japanese population Open
The etiology of pancreatic cancer remains largely unknown. Here, we report the results of a meta-analysis of three genome-wide association studies (GWASs) comprising 2,039 pancreatic cancer cases and 32,592 controls, the largest sample siz…
View article: Prediction model for pancreatic cancer risk in the general Japanese population
Prediction model for pancreatic cancer risk in the general Japanese population Open
Genome-wide association studies (GWASs) have identified many single nucleotide polymorphisms (SNPs) that are significantly associated with pancreatic cancer susceptibility. We sought to replicate the associations of 61 GWAS-identified SNPs…
View article: Comparison of surgical outcomes and complications between the Harmonic FOCUS and conventional surgery for open thyroidectomy
Comparison of surgical outcomes and complications between the Harmonic FOCUS and conventional surgery for open thyroidectomy Open
The aim of the present study was to evaluate the potential advantages of the ultrasonic scalpel compared with the conventional technique in thyroid surgery. Patients with resectable thyroid cancer and Basedow's disease were assigned to ult…
View article: Partnership between screening facilities and precision inspection facility
Partnership between screening facilities and precision inspection facility Open
近年の技術進歩に伴い，わが国の乳がん検診は画像診断が中心となっている。デジタルマンモグラフィのモニタ診断は普及し，過去の画像との比較読影が容易となった。検診および診療において，過去の画像との比較読影は参考となり重要である。どのような疾患においても病診連携は重要である。乳がん検診要精査例において治療の必要なしと診断された後の経過観察も必要であり，検診施設，精査施設との連携は大切である。 画像診断において，嚢胞，線維線種，過誤腫などの良性腫瘍は経過観察となる。特に細胞診あるいは…
View article: Examination for high-risk women in this hospital
Examination for high-risk women in this hospital Open
日本乳癌検診学会第２４回学術総会，ワークショップ２「ハイリスク女性に対する検診をどうするか」において解析をした１）case およびcontrol の症例数を増やし，再度解析をした。２０１５年１２月までに当院で手術を施行した原発乳癌４，８５４例（閉経前１，９７３例，閉経後２，８８１例）をcase，乳腺疾患のない当院外来受診者４，９１１例（閉経前２，６９６例，閉経後２，２１５例）をcontrol としてcase―control study を行った。３５歳未満（case：１６６…
View article: Alcohol consumption and mortality from aortic disease among Japanese men: The Japan Collaborative Cohort study
Alcohol consumption and mortality from aortic disease among Japanese men: The Japan Collaborative Cohort study Open
View article: Personal characteristics associated with individual degree of family function in residents of Rumoi City, Hokkaido
Personal characteristics associated with individual degree of family function in residents of Rumoi City, Hokkaido Open
Background We assessed the association of personal factors with Family APGAR not only among the subjects in nonsingle households, but also in single households. Methods We randomly chose 1 000 persons aged from 50 to 89 years in Rumoi City…
View article: The association between insulin resistance, metabolic syndrome, and ischemic heart disease among Rumoi residents
The association between insulin resistance, metabolic syndrome, and ischemic heart disease among Rumoi residents Open
Background It has widely been proven that metabolic syndrome (MetS) increases the risk of ischemic heart disease ( IHD ). MetS is confirmed based upon insulin resistance ( IR ). Our aim of this study is to evaluate the role of MetS and IR …
View article: Obesity, Diabetes Mellitus, Hypertension and other Risk Factors for Renal Cell Carcinoma in Japan: A Mini-Review
Obesity, Diabetes Mellitus, Hypertension and other Risk Factors for Renal Cell Carcinoma in Japan: A Mini-Review Open
Background: The incidence of kidney cancer is high in Western Europe, Northern Europe and North America, while it is low in Asia. Although the incidence of kidney cancer in Japan is lower than the rates in the other industrialized countrie…
View article: Insulin-like growth factor-1, IGF binding protein-3, and the risk of esophageal cancer in a nested case-control study
Insulin-like growth factor-1, IGF binding protein-3, and the risk of esophageal cancer in a nested case-control study Open
The free form of IGFBP3, which is estimated by this molar difference, may be inversely associated with esophageal cancer incidence.
View article: Association of Passive and Active Smoking with Elevated Blood Lead Levels Among Children and Adults Resided in a City of Japan
Association of Passive and Active Smoking with Elevated Blood Lead Levels Among Children and Adults Resided in a City of Japan Open
There were no previous reports assessing the effect of tobacco smoke on blood lead levels (BLLs) simultaneously in children and adults in Japan. We investigated the association of passive and active smoking with BLLs in children and adults…
View article: Lifestyle factors and the risk of kidney and bladder cancer in the Japanese population: A mini-review
Lifestyle factors and the risk of kidney and bladder cancer in the Japanese population: A mini-review Open
increasing in Japan.The proportion of elderly (i.e., 65 years or older) increased from 10. 5% in 1985 to 26.7% in 2015 [6].Smoking is a major risk factor for human cancer [3,7] and alcohol consumption has been suggested to increase the ris…
View article: Impact of longitudinal status change in metabolic syndrome defined by two different criteria on new onset of type 2 diabetes in a general Japanese population: the Tanno–Sobetsu Study
Impact of longitudinal status change in metabolic syndrome defined by two different criteria on new onset of type 2 diabetes in a general Japanese population: the Tanno–Sobetsu Study Open
View article: The influence of personality and perceived stress on the development of breast cancer: 20-year follow-up of 29,098 Japanese women
The influence of personality and perceived stress on the development of breast cancer: 20-year follow-up of 29,098 Japanese women Open