Mitu Dogra
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View article: Antibody-mediated rejection of transplanted kidney associated with anti-Jka alloantibodies: An interesting case report with review of literature
Antibody-mediated rejection of transplanted kidney associated with anti-Jka alloantibodies: An interesting case report with review of literature Open
There is increasing evidence for renal expression of non-ABO minor blood group antigens on the renal endothelium of the vasa recta and tubular epithelial cells. The role of antibodies to minor blood group antigens posing as an immunologica…
View article: A whistleblower direct antiglobulin test in chronic kidney disease: An interesting case of occult autoimmune hemolytic anemia in an undiagnosed lymphoma with pure red cell aplasia
A whistleblower direct antiglobulin test in chronic kidney disease: An interesting case of occult autoimmune hemolytic anemia in an undiagnosed lymphoma with pure red cell aplasia Open
A 67-year-old male, presented with urosepsis, severe anemia, advancing azotemia requiring blood transfusion. Patient grouped as O RhD positive. Antibody screening was pan-positive (4+). Similar strong pan-positivity seen on antibody identi…
View article: Cryopreservation of Hematopoietic Stem Cells for Pediatric Autologous Stem Cell Transplantation
Cryopreservation of Hematopoietic Stem Cells for Pediatric Autologous Stem Cell Transplantation Open
A BSTRACT Background and Objectives: Dimethylsulfoxide(DMSO) is gold standard for cryopreservation of hematopoietic progenitor cells (HPC) to reconstitute hematopoiesis in autologous stem cell transplants (auto-HSCT). Higher DMSO-related a…
View article: Antibody of Undetermined Specificity - The Eyes Do Not See What the Mind Does Not Know: Are You Dealing with a Low Prevalence Red Blood Cell Antigens?
Antibody of Undetermined Specificity - The Eyes Do Not See What the Mind Does Not Know: Are You Dealing with a Low Prevalence Red Blood Cell Antigens? Open
A BSTRACT For identification (ID) of irregular antibodies, a standard antibody identification (AI) panel consisting of 18 mandatory antigens expressed on reagent red blood cells is used. The phenotype for each antigen is listed on a red ce…
View article: A case report of occult weak 'A' subgroup: An important message for renal transplant physicians
A case report of occult weak 'A' subgroup: An important message for renal transplant physicians Open
Accurate ABO grouping is the cornerstone of a successful ABO-compatible organ transplant. While conventional methods identify blood groups accurately in most cases, rare and weak blood groups could occasionally be misread/missed. Weak A su…
View article: COVID-19 Convalescent Plasma Donor Characteristics: Correlation with Blood Group, Age, Gender, Symptoms and their Association with SARS CoV-2 Antibody Levels: A Bi-centric Study from India
COVID-19 Convalescent Plasma Donor Characteristics: Correlation with Blood Group, Age, Gender, Symptoms and their Association with SARS CoV-2 Antibody Levels: A Bi-centric Study from India Open
Background: Understanding demographics and collection characteristics of Convalescent Plasma (CP) donors is the corner stone for maintaining a viable inventory of high titre CP products in an acute-crisis setting. The Specific objectives o…
View article: Convalescent Plasma for COVID-19- is it Time to Say Goodbye? A Single-Center, Retrospective, Observational Study from Northern India
Convalescent Plasma for COVID-19- is it Time to Say Goodbye? A Single-Center, Retrospective, Observational Study from Northern India Open
Background: COVID-19 pandemic continues threatening the world with no effective treatment to tackle the menace. Till date, there is conflicting evidence on efficacy of CP in reducing COVID-19 related mortality. The objective of this study …
View article: Performance Evaluation: Four Chemiluminescent SARS-Cov-2 Immunoassays and Rapid-Card Test in Mild Disease and Seroprevalence of SARS CoV-2 in Frontline Healthcare Workers
Performance Evaluation: Four Chemiluminescent SARS-Cov-2 Immunoassays and Rapid-Card Test in Mild Disease and Seroprevalence of SARS CoV-2 in Frontline Healthcare Workers Open
Introduction: The COVID-19 pandemic raised a host of challenges to modern medicine. Key amongst these were in diagnostics, as most SARS-CoV-2 assays had been rapidly developed and released under emergency-use authorization with limited val…
View article: Two Sample Policy
Two Sample Policy Open
Background and Objectives: Pretransfusion testing has undergone remarkable changes over the past few decades starting from manual methods to semi-automation to full automation, but sample collection from the right person is out of scope of…
View article: Desensitization with plasma exchange in a patient with human leukocyte antigen donor-specific antibodies before T-cell-replete haploidentical hematopoietic stem cell transplantation
Desensitization with plasma exchange in a patient with human leukocyte antigen donor-specific antibodies before T-cell-replete haploidentical hematopoietic stem cell transplantation Open
The presence of human leukocyte antigen (HLA) donor-specific antibodies (DSAs) increases the risk of graft failure in T-cell-replete haploidentical hematopoietic stem cell transplantation (haploidentical-HSCT). We report a case of a 20-yea…
View article: Are we missing out something in donor notification?
Are we missing out something in donor notification? Open
Background: Donor notification is an integral part of any blood collection facility. But regarding DAT positive donors there are no standard guidelines to notify them or to refer them to any clinician. Aim of this study was to suggest poss…
View article: Daratumumab (Anti-CD38) interference with serological testing: An emerging challenge for blood banks in developing countries
Daratumumab (Anti-CD38) interference with serological testing: An emerging challenge for blood banks in developing countries Open
Daratumumab (DARA), a monoclonal anti-CD38 antibody, belongs to the new generation of immunotherapy in refractory relapsed multiple myeloma. CD38 is weakly expressed on human erythrocytes. By its intrinsic anti-CD38 activity, DARA also int…
View article: Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program
Transfusion-related adverse reactions: From institutional hemovigilance effort to National Hemovigilance program Open
Factors such as clerical checks at various levels, improvement in blood storage conditions outside blood banks, leukodepletion, better inventory management, careful donor screening, bedside monitoring of transfusion, and documentation of a…