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View article: GW231123: A Binary Black Hole Merger with Total Mass 190–265 <i>M</i> <sub>⊙</sub>
GW231123: A Binary Black Hole Merger with Total Mass 190–265 <i>M</i> <sub>⊙</sub> Open
On 2023 November 23, the two LIGO observatories both detected GW231123, a gravitational-wave signal consistent with the merger of two black holes with masses and (90% credible intervals), at a luminosity dis…
View article: The Intranasal Administration of Semaphorin 3A Inhibitor in a Mouse Model of Olfactory Disorder
The Intranasal Administration of Semaphorin 3A Inhibitor in a Mouse Model of Olfactory Disorder Open
View article: Table S7 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S7 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S7. Univariate and multivariate analyses of the PFS in the LC cohort
View article: Data from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Data from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Cancer-associated fibroblasts (CAF) play immunosuppressive roles in the tumor microenvironment. Specifically, they reportedly act as physical barriers preventing immune cell infiltration. However, the spatial relationships between CAFs and…
View article: Table S6 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S6 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S6. Univariate and multivariate analyses of the OS in the HNC cohort
View article: Table S3 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S3 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S3. Patient characteristics in the HNC cohort (n = 86).
View article: Supplementary Figure S2 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Figure S2 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Figure S2. Additional gene expression data between sFB and mFB constructs
View article: Supplementary Figure S3 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Figure S3 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Figure S3. Additional in vitro data on the TGF-β and periostin crosstalk.
View article: Table S2 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S2 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S2. List of primers used for quantitative reverse transcription-polymerase chain reaction (qRT-PCR).
View article: Supplementary Table S1 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Table S1 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Table S1. Sequences of all constructs
View article: Table S8 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S8 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S8. Univariate and multivariate analyses of the OS in the LC cohort
View article: Supplementary Figure S1 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Figure S1 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Figure S1. Characteristic of our used mouse immortalized fibroblasts (FBs) and additional IFNɤ production data between sFB and mFB coculture models
View article: Supplementary Figure S4 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Figure S4 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Figure S4. Additional in vivo efficacy of PD-1 blockade
View article: Supplementary Figure S5 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Supplementary Figure S5 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Supplementary Figure S5. Additional clinical sample data.
View article: Table S4 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S4 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S4. Patient characteristics in the LC cohort (n = 49).
View article: Table S5 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity
Table S5 from Close Spatial Interactions between Cancer Cells and Cancer-Associated Fibroblasts Suppress Antitumor Immunity Open
Table S5. Univariate and multivariate analyses of the PFS in the HNC cohort
View article: Exploring factors influencing the hearing test and hearing aid adoption among the Japanese elderly: Implications of recognizing the hearing loss-dementia relationship
Exploring factors influencing the hearing test and hearing aid adoption among the Japanese elderly: Implications of recognizing the hearing loss-dementia relationship Open
View article: A Higher Liver Fibrosis-4 Index Is Associated With More Severe Hearing Loss in Idiopathic Sudden Sensorineural Hearing Loss
A Higher Liver Fibrosis-4 Index Is Associated With More Severe Hearing Loss in Idiopathic Sudden Sensorineural Hearing Loss Open
Background Liver fibrosis is an important medical issue increasing over time in developed countries. Aims/objectives This study aimed to investigate whether liver fibrosis, as indicated by routine blood test parameters, influences the risk…
View article: All-sky search for short gravitational-wave bursts in the first part of the fourth LIGO-Virgo-KAGRA observing run
All-sky search for short gravitational-wave bursts in the first part of the fourth LIGO-Virgo-KAGRA observing run Open
We present a search for short-duration gravitational-wave transients in data from the first eight months of Advanced LIGO-Virgo-KAGRA's fourth observing run, denoted O4a. We use four analyses which are sensitive to a wide range of potentia…
View article: Near-infrared photoimmunotherapy for recurrent cancer at the base of the tongue
Near-infrared photoimmunotherapy for recurrent cancer at the base of the tongue Open
Near-infrared photoimmunotherapy (NIR-PIT) is a novel therapeutic approach that targets epidermal growth factor receptor (EGFR). In NIR-PIT, administration of cetuximab sarotalocan sodium is followed by laser irradiation of the affected ar…
View article: Search for Continuous Gravitational Waves from Known Pulsars in the First Part of the Fourth LIGO-Virgo-KAGRA Observing Run
Search for Continuous Gravitational Waves from Known Pulsars in the First Part of the Fourth LIGO-Virgo-KAGRA Observing Run Open
Continuous gravitational waves (CWs) emission from neutron stars carries information about their internal structure and equation of state, and it can provide tests of general relativity. We present a search for CWs from a set of 45 known p…
View article: A glucocorticoid-regulating molecule, Fkbp5, may interact with mitogen-activated protein kinase signaling in the organ of Corti of mice cochleae
A glucocorticoid-regulating molecule, Fkbp5, may interact with mitogen-activated protein kinase signaling in the organ of Corti of mice cochleae Open
FKBP5 is a 51-Da FK506-binding protein and member of the immunophilin family involved in controlling the signaling of glucocorticoid receptor from the cytosol to nucleus. Fkbp5 has previously been shown to be expressed in murine cochlear t…
View article: Association Between Dinner-to-Bed Time and Gastroesophageal Reflux-Related Diseases in Children
Association Between Dinner-to-Bed Time and Gastroesophageal Reflux-Related Diseases in Children Open
This study showed that dinner-to-bed time within 120 minutes after dinner increases the risk of developing asthma. This underscores the importance of considering lifestyle modifications, as certain pediatric asthma cases may be influenced …
View article: Short‐process incudo‐stapedioplasty in congenital ear malformation
Short‐process incudo‐stapedioplasty in congenital ear malformation Open
Objectives Although various stapedotomy and stapedectomy techniques exist, anchoring the piston can be challenging. We present a novel surgical approach for treating congenital stapes malformations with an atypical facial nerve trajectory.…
View article: Near-Infrared Photoimmunotherapy for Recurrent Cancer at the Base of the Tongue
Near-Infrared Photoimmunotherapy for Recurrent Cancer at the Base of the Tongue Open
View article: Search for gravitational waves emitted from SN 2023ixf
Search for gravitational waves emitted from SN 2023ixf Open
We present the results of a search for gravitational-wave transients associated with core-collapse supernova SN 2023ixf, which was observed in the galaxy Messier 101 via optical emission on 2023 May 19th, during the LIGO-Virgo-KAGRA 15th E…
View article: A search using GEO600 for gravitational waves coincident with fast radio bursts from SGR 1935+2154
A search using GEO600 for gravitational waves coincident with fast radio bursts from SGR 1935+2154 Open
The magnetar SGR 1935+2154 is the only known Galactic source of fast radio bursts (FRBs). FRBs from SGR 1935+2154 were first detected by CHIME/FRB and STARE2 in 2020 April, after the conclusion of the LIGO, Virgo, and KAGRA Collaborations'…
View article: Observation of Gravitational Waves from the Coalescence of a 2.5–4.5 M <sub>⊙</sub> Compact Object and a Neutron Star
Observation of Gravitational Waves from the Coalescence of a 2.5–4.5 M <sub>⊙</sub> Compact Object and a Neutron Star Open
We report the observation of a coalescing compact binary with component masses 2.5–4.5 M ⊙ and 1.2–2.0 M ⊙ (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth ob…
View article: Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run Open
We present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search i…
View article: Supplementary Table S6 from CD106 in Tumor-Specific Exhausted CD8<sup>+</sup> T Cells Mediates Immunosuppression by Inhibiting TCR Signaling
Supplementary Table S6 from CD106 in Tumor-Specific Exhausted CD8<sup>+</sup> T Cells Mediates Immunosuppression by Inhibiting TCR Signaling Open
Differentially expressed genes between the exhausted CD8+ T cells and the others