Manju Sharma
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View article: Evolution, Current State, and Anticipated Future of Telecommunications Network Architecture with Particular Focus on 6G Developments, Software-Defined Networks, Edge Intelligence, Open and Disaggregated Radio Access Networks
Evolution, Current State, and Anticipated Future of Telecommunications Network Architecture with Particular Focus on 6G Developments, Software-Defined Networks, Edge Intelligence, Open and Disaggregated Radio Access Networks Open
Telecommunications engineering is entering a transformative era driven by rapid innovations in wireless communication, artificial intelligence, cloud computing, satellite networks, and distributed digital ecosystems. As global connectivity…
View article: A Theoretical Comparative Study of Privacy Mechanisms and Optimization Techniques in Federated Learning for Edge AI
A Theoretical Comparative Study of Privacy Mechanisms and Optimization Techniques in Federated Learning for Edge AI Open
Federated Learning (FL) enables decentralized model training across edge devices while keeping raw data local, thereby enhancing privacy and reducing communication costs. However, theoretical challenges remain: reconciling model utility wi…
View article: Machine Learning for 6G Wireless Networks: Paradigms, Enablers, and the Pursuit of AI-Native Trustworthiness
Machine Learning for 6G Wireless Networks: Paradigms, Enablers, and the Pursuit of AI-Native Trustworthiness Open
The sixth generation (6G) of wireless communication systems is envisioned to be inherently AI-native, integrating intelligence into every network layer to support unprecedented capabilities, including terabit-per-second data rates, submill…
View article: Blocklance - A Blockchain Powered Freelancing Platform
Blocklance - A Blockchain Powered Freelancing Platform Open
The global gig economy relies heavily on centralized freelance platforms, which face many problems like high fees for intermediaries, payment disputes, and a lack of transparency. Clients may not receive their work after paying, and freela…
View article: Prevalence of Elevated Lipoprotein A (Lp(A)) in Nepalese Patients with Traditional Risk Factors of Atherosclerotic Cardiovascular Disease (ASCVD)
Prevalence of Elevated Lipoprotein A (Lp(A)) in Nepalese Patients with Traditional Risk Factors of Atherosclerotic Cardiovascular Disease (ASCVD) Open
Background and aims: One important residual CVD risks is elevated level of lipoprotein a (Lp(a)). High Lp(a) level is atherogenic. It’s higher prevalence in South Asian population is important because of a higher prevalence of premature co…
View article: Reirradiation clinical practice in gastrointestinal abdominal malignancies: an international reirradiation collaborative group (ReCOG) systematic review
Reirradiation clinical practice in gastrointestinal abdominal malignancies: an international reirradiation collaborative group (ReCOG) systematic review Open
Reirradiation in abdominal malignancies appears to be able to achieve meaningful local control and survival in select patients, though heterogeneity in planning, dosing, and toxicity reporting remains a major challenge for establishing bes…
View article: Determinants and Warning Signs of Inpatient Falls and Fall-Related Injuries in Tertiary Hospitals, Chennai
Determinants and Warning Signs of Inpatient Falls and Fall-Related Injuries in Tertiary Hospitals, Chennai Open
Background: Inpatient falls are among the most common adverse events in hospital settings and can lead to serious injuries, increased hospital stays, and higher healthcare costs. Identifying the determinants and warning signs of falls is e…
View article: The Contribution of Microplastics to Marine Pollution
The Contribution of Microplastics to Marine Pollution Open
The entry of microplastics into the world's oceans is now a critical global environmental concern. Microplastics, or man-made polymer particles with diameters of less than five millimeters, are the byproduct of a diverse array of human act…
View article: Possible Viral Interference Leading to Protection from Subsequent Respiratory Viral Infections – Results of an Observational Study at a Singapore Teaching Hospital
Possible Viral Interference Leading to Protection from Subsequent Respiratory Viral Infections – Results of an Observational Study at a Singapore Teaching Hospital Open
Introduction: Respiratory infections, affecting mainly young children and the elderly, pose significant global health threats. While protection from related strains of viruses like influenza is well-documented, cross-protection among diffe…
View article: Evaluation of real-time polymerase chain reaction for detection of Strongyloides stercoralis in immunocompromised patients in North India
Evaluation of real-time polymerase chain reaction for detection of Strongyloides stercoralis in immunocompromised patients in North India Open
Introduction: The diagnosis of Strongyloides stercoralis remains challenging as the commonly used stool microscopy has poor sensitivity, culture is cumbersome to perform, and serology is not always indicative of current infection. In this …
View article: Short-term carbon mineralization from soils under different land uses in northwest India
Short-term carbon mineralization from soils under different land uses in northwest India Open
Soil respiration is an indicator of soil microbial activities. Soil respiration rates vary significantly with soil type and structure, but these relationships are not fully understood. This study investigated the controls of soil respirati…
View article: Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo
Matrix stiffness modulated release of spheroid-derived extracellular vesicles and discovery of Piezo1 cargo Open
Augmented extracellular matrix (ECM) stiffness is a mechanical hallmark of cancer. Mechanotransduction studies have extensively probed the mechanisms by which ECM stiffness regulates intracellular communication. However, the influence of s…
View article: Investigating the cardioprotective potential of quercetin against tacrolimus-induced cardiotoxicity in Wistar rats: A mechanistic insights
Investigating the cardioprotective potential of quercetin against tacrolimus-induced cardiotoxicity in Wistar rats: A mechanistic insights Open
Purpose The aim of this research study is to assess the ability of quercetin to protect the heart from the negative consequences of tacrolimus-induced cardiotoxicity. Methods A total of 30 rats were divided into 5 groups. Tacrolimus was us…
View article: Exploration of quantitative and qualitative traits of pigeonpea [Cajanus cajan (L.) Milsp.] to understand the genetic diversity
Exploration of quantitative and qualitative traits of pigeonpea [Cajanus cajan (L.) Milsp.] to understand the genetic diversity Open
Pigeonpea [Cajanus cajan (L.) Milsp.] is an important leguminous crop with high protein content and nutritional value in tropical and subtropical regions. To assess the genetic diversity and correlation among qualitative and quantitative p…
View article: “A Study To Assess The Effectiveness Of Structured Teaching Programme On Knowledge Regarding Early Ambulation On Laparoscopic Cholecystectomy Patients In Apollo Speciality Hospitals, Jayanagar, Bangalore (India).”
“A Study To Assess The Effectiveness Of Structured Teaching Programme On Knowledge Regarding Early Ambulation On Laparoscopic Cholecystectomy Patients In Apollo Speciality Hospitals, Jayanagar, Bangalore (India).” Open
Laparoscopic cholecystectomy is the treatment of choice for gall bladder stone disease. Difficult cholecystectomy is associated with serious complications and a high conversion rate. The aim of this study was to review the current strategi…
View article: Lipopolysaccharide targeting-peptide-capped chitosan gold nanoparticles for laser-induced antibacterial activity
Lipopolysaccharide targeting-peptide-capped chitosan gold nanoparticles for laser-induced antibacterial activity Open
Aim: We present the synthesis of anti-bacterial gold nanoparticles using chitosan as a dual-functional agent. The resulting ChAuNPs were further modified with a lipopolysaccharide-targeting antibacterial peptide to aid in biocompati…
View article: Genome wide association study of antioxidant activity in pigeonpea germplasm
Genome wide association study of antioxidant activity in pigeonpea germplasm Open
Pigeonpea (Cajanus cajan L.) is a nutritious crop with antioxidant potential, making it valuable for health supplements and medicinal products. Pigeonpea seed coat possess a rich source of antioxidant properties, particularly in dark colou…
View article: Testing the Effectiveness of a Mindfulness- and Acceptance-Based Smartphone App for Nurses Traumatized by the COVID-19 Pandemic: A Pilot Study
Testing the Effectiveness of a Mindfulness- and Acceptance-Based Smartphone App for Nurses Traumatized by the COVID-19 Pandemic: A Pilot Study Open
A significant proportion of frontline nurses developed post-traumatic stress disorder (PTSD) symptoms as a result of working during the COVID-19 pandemic. This study aimed to determine the efficacy of a mindfulness- and acceptance-based sm…
View article: Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids
Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids Open
Extracellular biophysical cues such as matrix stiffness are key stimuli tuning cell fate and affecting tumor progression in vivo. However, it remains unclear how cancer spheroids in a 3D microenvironment perceive matrix mechanical stiffnes…
View article: Minimize various expenses arising during production-distribution planning under imprecise demands and production quantity by using fuzzy optimization approach
Minimize various expenses arising during production-distribution planning under imprecise demands and production quantity by using fuzzy optimization approach Open
In this paper, we have constructed a realistic model of production-distribution in which we have minimized the various expenses which arises during planning of production-distribution and this minimization is carried out by utilizing the f…
View article: Additions to the Flora of Himachal Pradesh, North-West Himalaya
Additions to the Flora of Himachal Pradesh, North-West Himalaya Open
Botanical explorations were made in Chamba district of Himachal Pradesh from 1984-1988 under "BSI District Flora Project" sponsored by Botanical Survey of India. Consequently, studies on phytogeography (Singh & Sharma 1989, Sharma & Singh …
View article: Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles
Oncogenic ETS fusions promote DNA damage and proinflammatory responses via pericentromeric RNAs in extracellular vesicles Open
Aberrant expression of the E26 transformation-specific (ETS) transcription factors characterizes numerous human malignancies. Many of these proteins, including EWS:FLI1 and EWS:ERG fusions in Ewing sarcoma (EwS) and TMPRSS2:ERG in prostate…
View article: Prevalence of anemia among chronic myeloid leukemia patients treated with Imatinib: A evidence based meta-analysis.
Prevalence of anemia among chronic myeloid leukemia patients treated with Imatinib: A evidence based meta-analysis. Open
Aim- Imatinib is one of the tyrosine kinase inhibitors used for the treatment of chronic myeloid leukemia (CML) patients. The exact association of imatinib with anemia in CML patients is still unclear. The current study aimed to find the p…
View article: Rapid purification and multiparametric characterization of circulating small extracellular vesicles utilizing a label-free lab-on-a-chip device
Rapid purification and multiparametric characterization of circulating small extracellular vesicles utilizing a label-free lab-on-a-chip device Open
View article: Animal models for induction of diabetes and its complications
Animal models for induction of diabetes and its complications Open
View article: Inhibitory effects of herbal medicines with claimed anticancer indications on cytochrome P450—An evaluation of drug-herb interactions risk
Inhibitory effects of herbal medicines with claimed anticancer indications on cytochrome P450—An evaluation of drug-herb interactions risk Open
Herbs have the potential to interact with conventional medicines or each other upon concurrent administration. This can be at the level of absorption, distribution, metabolism and excretion (ADME). With an estimation that 80% of the popula…
View article: Retraction Note: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. Stem bark (ALEx) on streptozotocin induced diabetic rats
Retraction Note: Antidiabetic, renal/hepatic/pancreas/cardiac protective and antioxidant potential of methanol/dichloromethane extract of Albizzia Lebbeck Benth. Stem bark (ALEx) on streptozotocin induced diabetic rats Open
View article: Retraction Note: Antidiabetic, antioxidant, antihyperlipidemic effect of extract of Euryale ferox salisb. With enhanced histopathology of pancreas, liver and kidney in streptozotocin induced diabetic rats
Retraction Note: Antidiabetic, antioxidant, antihyperlipidemic effect of extract of Euryale ferox salisb. With enhanced histopathology of pancreas, liver and kidney in streptozotocin induced diabetic rats Open
View article: Rapid purification and multiparametric characterization of circulating small extracellular vesicles utilizing a label-free lab-on-a-chip device
Rapid purification and multiparametric characterization of circulating small extracellular vesicles utilizing a label-free lab-on-a-chip device Open
Nano-scale extracellular vesicles are lipid-bilayer delimited particles that are naturally secreted by all cells and have emerged as valuable biomarkers for a wide range of diseases. Efficient isolation of small extracellular vesicles whil…
View article: Congenital Junctional Ectopic Tachycardia in a 6-month-old boy treated with Ivabradine: A Case Report
Congenital Junctional Ectopic Tachycardia in a 6-month-old boy treated with Ivabradine: A Case Report Open
Congenital junctional ectopic tachycardia (JET) is a rare tachyarrhythmia found in young infants and is often difficult to treat. JET is characterized by incessant tachycardia which causes ventricular dysfunction, heart failure and high mo…