Paul Moayyedi
YOU?
Author Swipe
View article: Supplementary Figure from eQTL Set–Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma
Supplementary Figure from eQTL Set–Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma Open
Supplementary Figure from eQTL Set–Based Association Analysis Identifies Novel Susceptibility Loci for Barrett Esophagus and Esophageal Adenocarcinoma
View article: Population screening for Helicobacter pylori to reduce gastric cancer
Population screening for Helicobacter pylori to reduce gastric cancer Open
View article: Micronutrient Deficiencies Associated with a Gluten-Free Diet in Patients with Celiac Disease and Non-Celiac Gluten or Wheat Sensitivity: A Systematic Review and Meta-Analysis
Micronutrient Deficiencies Associated with a Gluten-Free Diet in Patients with Celiac Disease and Non-Celiac Gluten or Wheat Sensitivity: A Systematic Review and Meta-Analysis Open
Background: A gluten-free diet (GFD) has been shown to be nutritionally inadequate for those with wheat-related disorders. However, the differences in findings and the absence of quantitative analysis limits the interpretation of previous …
View article: Fecal CD200 as a Measure of Immunosuppressive CD200L and Proinflammatory CD200S at the Feto‐Maternal Interface
Fecal CD200 as a Measure of Immunosuppressive CD200L and Proinflammatory CD200S at the Feto‐Maternal Interface Open
Problem Patients with diarrhea‐predominant irritable bowel syndrome have an increased risk of recurrent miscarriage (RM). Loss of chromosomally normal post‐implantation embryos is triggered by the proinflammatory cytokines interferon‐γ and…
View article: Phage intervention improves colitis and response to corticosteroids by attenuating virulence of Crohn's disease-associated bacteria
Phage intervention improves colitis and response to corticosteroids by attenuating virulence of Crohn's disease-associated bacteria Open
Adherent-invasive Escherichia coli (AIEC) exhibit proinflammatory properties and have been implicated in the pathogenesis of Crohns disease (CD), a form of inflammatory bowel disease (IBD). Antibiotic use in CD lacks specificity and may wo…
View article: Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease (INTERBLEED): a case control study
Risk factors associated with gastrointestinal bleeding in patients with cardiovascular disease (INTERBLEED): a case control study Open
Aims This study aimed to identify and quantify the importance of risk factors for gastrointestinal (GI) bleeding in patients with CV disease. Methods and results We conducted a case-control study in 9 countries in Asia, America, Europe, an…
View article: Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise
Detecting microbial engraftment after FMT using placebo sequencing and culture enriched metagenomics to sort signals from noise Open
View article: A168 DIFFERENTIAL ASSOCIATION OF DIETARY FIBER INTAKE WITH METABOLOMIC AND PROTEOMIC SIGNATURES LINKED TO THE RISK OF CD
A168 DIFFERENTIAL ASSOCIATION OF DIETARY FIBER INTAKE WITH METABOLOMIC AND PROTEOMIC SIGNATURES LINKED TO THE RISK OF CD Open
Background Epidemiologic studies have shown that increased dietary fiber intake may be associated with a reduced risk of developing Crohn’s disease (CD). Our previous research identified specific patterns of serum proteomics and metabolomi…
View article: A11 FERMENTABLE DIETARY FIBER INTAKE IS ASSOCIATED WITH A DECREASED RISK OF DEVELOPING CROHN’S DISEASE IN HEALTHY FIRST-DEGREE RELATIVES
A11 FERMENTABLE DIETARY FIBER INTAKE IS ASSOCIATED WITH A DECREASED RISK OF DEVELOPING CROHN’S DISEASE IN HEALTHY FIRST-DEGREE RELATIVES Open
Background The cause of Crohn’s Disease (CD) remains unclear; however evidence suggests that diet plays a key role. With a rising incidence and no definitive cure, identification of modifiable risk factors is critical in preventing CD deve…
View article: A156 FECAL PROTEOLYTIC ACTIVITY IS ASSOCIATED WITH SYMPTOMATIC STATUS IN CROHN’S DISEASE
A156 FECAL PROTEOLYTIC ACTIVITY IS ASSOCIATED WITH SYMPTOMATIC STATUS IN CROHN’S DISEASE Open
Background An imbalance in host proteolytic activity (PA) has been reported in patients with inflammatory bowel disease (IBD) versus healthy controls (HCs). Fecal PA increases before the diagnosis of ulcerative colitis (UC) which is proinf…
View article: A62 UNCOVERING MICROBIAL DETERMINANTS OF IBS FLARE-UPS: COHORT-LEVEL VS PATIENT-SPECIFIC APPROACHES
A62 UNCOVERING MICROBIAL DETERMINANTS OF IBS FLARE-UPS: COHORT-LEVEL VS PATIENT-SPECIFIC APPROACHES Open
Background Irritable bowel syndrome (IBS) is a complex gastrointestinal disorder with a global prevalence of 3.8% (5.8% in Canada, using Rome IV criteria), with the gut microbiota implicated in its pathophysiology. Despite extensive resear…
View article: Eradication Therapy to Prevent Gastric Cancer in Helicobacter pylori–Positive Individuals: Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies
Eradication Therapy to Prevent Gastric Cancer in Helicobacter pylori–Positive Individuals: Systematic Review and Meta-Analysis of Randomized Controlled Trials and Observational Studies Open
This meta-analysis provides further evidence that administering eradication therapy prevents gastric cancer in H pylori-positive individuals, with consistency in results among studies of different design.
View article: Management of Patients With Refractory Reflux‐Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence‐Based Consensus Statements
Management of Patients With Refractory Reflux‐Like Symptoms Despite Proton Pump Inhibitor Therapy: Evidence‐Based Consensus Statements Open
Background Many patients diagnosed with gastro‐oesophageal reflux disease (GERD) have persistent symptoms despite proton pump inhibitor (PPI) therapy. Aims The aim of this consensus is to provide evidence‐based statements to guide clinicia…
View article: Preliminary Results From a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients With Mild-to-Moderate Crohn's Disease
Preliminary Results From a Multicenter, Randomized Trial Using Fecal Microbiota Transplantation to Induce Remission in Patients With Mild-to-Moderate Crohn's Disease Open
INTRODUCTION: Fecal microbiota transplantation (FMT) has shown promise at inducing remission in ulcerative colitis. This study is the first of its kind to evaluate the efficacy and safety of FMT at inducing remission in Crohn's disease (CD…
View article: Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn’s Disease
Healthy First-Degree Relatives From Multiplex Families vs Simplex Families Have Higher Subclinical Intestinal Inflammation, a Distinct Fecal Microbial Signature, and Harbor a Higher Risk of Developing Crohn’s Disease Open
View article: Impaired Epithelial CD200L Tolerance Signaling in Irritable Bowel Syndrome Cases With Diarrhea May Be Associated With Recurrent Miscarriages
Impaired Epithelial CD200L Tolerance Signaling in Irritable Bowel Syndrome Cases With Diarrhea May Be Associated With Recurrent Miscarriages Open
Problem There is a higher incidence of irritable bowel syndrome with miscarriages, and recurrent miscarriages of otherwise normal embryos have been linked to subnormal expression of the immune checkpoint inhibitor CD200L. We sought to dete…
View article: Incidence and predictors of major gastrointestinal bleeding in patients on aspirin, low‐dose rivaroxaban, or the combination: Secondary analysis of the <scp>COMPASS</scp> randomised controlled trial
Incidence and predictors of major gastrointestinal bleeding in patients on aspirin, low‐dose rivaroxaban, or the combination: Secondary analysis of the <span>COMPASS</span> randomised controlled trial Open
Summary Background The incidence of major gastrointestinal bleeding (GIB) in patients on low‐dose direct‐acting oral anticoagulants (DOACs) is relatively unknown. Estimates from randomised controlled trials (RCTs) are lacking. Aims To asse…
View article: Adverse Events Associated With Proton Pump Inhibitors: Fact vs Fiction.
Adverse Events Associated With Proton Pump Inhibitors: Fact vs Fiction. Open
View article: Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding: a Cochrane review
Proton pump inhibitor treatment initiated prior to endoscopic diagnosis in upper gastrointestinal bleeding: a Cochrane review Open
revisiones Cochrane se actualizan regularmente a medida que
View article: Two Years Gone
Two Years Gone Open
View article: Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society (ANMS)
Critical appraisal of the SIBO hypothesis and breath testing: A clinical practice update endorsed by the European society of neurogastroenterology and motility (ESNM) and the American neurogastroenterology and motility society (ANMS) Open
Background There is compelling evidence that microbe‐host interactions in the intestinal tract underlie many human disorders, including disorders of gut‐brain interactions (previously termed functional bowel disorders), such as irritable b…
View article: Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis
Effect of Brain-Gut Behavioral Treatments on Abdominal Pain in Irritable Bowel Syndrome: Systematic Review and Network Meta-Analysis Open
Several BGBTs, including self-guided/minimal contact CBT, face-to-face multicomponent behavioral therapy, and face-to-face gut-directed hypnotherapy may be efficacious for abdominal pain in IBS, although none was superior to another.
View article: A15 LEVERAGING CULTURE-DEPENDENT AND -INDEPENDENT METAGENOMICS TO IDENTIFY ENTEROBACTERIACEAE GENES ASSOCIATED WITH ACTIVE ULCERATIVE COLITIS
A15 LEVERAGING CULTURE-DEPENDENT AND -INDEPENDENT METAGENOMICS TO IDENTIFY ENTEROBACTERIACEAE GENES ASSOCIATED WITH ACTIVE ULCERATIVE COLITIS Open
Background Ulcerative colitis (UC) is a type of inflammatory bowel disease (IBD) that is restricted to the large intestine and is characterized by mucosal inflammation. There is evidence that pathogenic bacteria contribute to UC pathogenes…
View article: A273 A PILOT PROSPECITVE, MULTI-CENTRE, RANDOMIZED CONTROLLED TRIAL COMPARING FECAL MICROBIOTA TRANSPLANTATION (FMT) TO PLACEBO AT INDUCING REMISSION IN MILD TO MODERATE CROHN'S DISEASE
A273 A PILOT PROSPECITVE, MULTI-CENTRE, RANDOMIZED CONTROLLED TRIAL COMPARING FECAL MICROBIOTA TRANSPLANTATION (FMT) TO PLACEBO AT INDUCING REMISSION IN MILD TO MODERATE CROHN'S DISEASE Open
Background FMT has shown promise at inducing remission in ulcerative colitis. The effect of FMT on inducing remission in Crohn’s disease however remains unknown. Aims To evaluate the efficacy of FMT at inducing remission in mild-to-moderat…
View article: A275 THE POTENTIAL MECHANISTIC ROLES OF SPHINGOLIPIDS IN HEALTHY FIRST-DEGREE RELATIVES OF PATIENTS WITH CROHN'S DISEASE
A275 THE POTENTIAL MECHANISTIC ROLES OF SPHINGOLIPIDS IN HEALTHY FIRST-DEGREE RELATIVES OF PATIENTS WITH CROHN'S DISEASE Open
Background Crohn's Disease(CD) features a complex etiology intertwining genetic, environmental, and immunological dimensions. Sphingolipids (SPs) are pivotal lipid molecules within cell membranes and various biological processes, including…
View article: A22 INVESTIGATING THE EFFECTS OF DIET TRIGGER DISCLOSURE ON BEHAVIOUR IN IRRITABLE BOWEL SYNDROME (IBS) PATIENTS WITH PERCEIVED GLUTEN SENSITIVITY
A22 INVESTIGATING THE EFFECTS OF DIET TRIGGER DISCLOSURE ON BEHAVIOUR IN IRRITABLE BOWEL SYNDROME (IBS) PATIENTS WITH PERCEIVED GLUTEN SENSITIVITY Open
Background Patients with self-perceived gluten sensitivity often undergo double-blinded, placebo-controlled (DBPC) challenge studies to determine whether gluten or wheat trigger their symptoms. However, it is unknown whether the result dis…
View article: Understanding Predictors of Crohn’s Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn’s Disease
Understanding Predictors of Crohn’s Disease: Determinants of Altered Barrier Function in Pre-Disease Phase of Crohn’s Disease Open
The pathogenesis of Crohn’s disease (CD) remains unknown. The current working theory is that genetic susceptibility influences host–microbe interactions, resulting in chronic inflammation. Case–control studies fail to explain the triggers …
View article: Ultra-Processed Grains and Risk of Inflammatory Bowel Disease: Results from the Prospective Urban Rural Epidemiology (PURE) Study
Ultra-Processed Grains and Risk of Inflammatory Bowel Disease: Results from the Prospective Urban Rural Epidemiology (PURE) Study Open
View article: Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis
Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis Open
Some combinations of probiotics or strains may be beneficial in IBS. However, certainty in the evidence for efficacy by GRADE criteria was low to very low across almost all of our analyses.
View article: Hemorrhage From Left Hepatic Artery Pseudoaneurysm as a Complication of Acute Pancreatitis in a Patient With Fibromuscular Dysplasia
Hemorrhage From Left Hepatic Artery Pseudoaneurysm as a Complication of Acute Pancreatitis in a Patient With Fibromuscular Dysplasia Open
Hepatic artery pseudoaneurysms are a rare complication of pancreatitis, and their rupture and bleeding cause high mortality. We present the case of a 76-year-old woman with fibromuscular dysplasia who developed a new left hepatic artery ps…