Mohamad Moustafa Ali
YOU?
Author Swipe
View article: The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma
The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma Open
View article: Paracentrotus lividus sea urchin gonadal extract mitigates neurotoxicity and inflammatory signaling in a rat model of Parkinson’s disease
Paracentrotus lividus sea urchin gonadal extract mitigates neurotoxicity and inflammatory signaling in a rat model of Parkinson’s disease Open
The present study investigates the neuroprotective effects of the sea urchin Paracentrotus lividus gonadal extract on rotenone-induced neurotoxicity in a Parkinson’s disease (PD) rat model. Parkinson’s disease, characterized by the progres…
View article: ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness Open
View article: Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt
Characterization and biological applications of gonadal extract of Paracentrotus lividus collected along the Mediterranean coast of Alexandria, Egypt Open
Marine invertebrates represent a valuable reservoir of pharmaceutical bioactive compounds with potential relevance to various medical applications. These compounds exhibit notable advantages when compared to their terrestrial counterparts,…
View article: Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts
Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts Open
Cutaneous squamous cell carcinoma (cSCC) is a fast-increasing cancer with metastatic potential. Extracellular vesicles (EVs) are small membrane-bound vesicles that play important roles in intercellular communication, particularly in the tu…
View article: Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells
Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells Open
View article: CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence
CD44 Depletion in Glioblastoma Cells Suppresses Growth and Stemness and Induces Senescence Open
Glioblastoma multiforme (GBM) is a lethal brain tumor, characterized by enhanced proliferation and invasion, as well as increased vascularization and chemoresistance. The expression of the hyaluronan receptor CD44 has been shown to correla…
View article: Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges
Neural Stem Cell-Based Therapies and Glioblastoma Management: Current Evidence and Clinical Challenges Open
Gliomas, which account for nearly a quarter of all primary CNS tumors, present significant contemporary therapeutic challenges, particularly the highest-grade variant (glioblastoma multiforme), which has an especially poor prognosis. These…
View article: The DNA damage inducible lncRNA SCAT7 regulates genomic integrity and topoisomerase 1 turnover in lung adenocarcinoma
The DNA damage inducible lncRNA SCAT7 regulates genomic integrity and topoisomerase 1 turnover in lung adenocarcinoma Open
Despite the rapid improvements in unveiling the importance of lncRNAs in all aspects of cancer biology, there is still a void in mechanistic understanding of their role in the DNA damage response. Here we explored the potential role of the…
View article: S-phase cancer associated lncRNAs
S-phase cancer associated lncRNAs Open
Comment on: Ali MM, et al. Nature Communications 2018; 9:883.
View article: PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers Open