Mohamed Abdel‐Hamid
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View article: Cancer and Aging Biomarkers: Classification, Early Detection Technologies and Emerging Research Trends
Cancer and Aging Biomarkers: Classification, Early Detection Technologies and Emerging Research Trends Open
Cancer and aging are two distinct biological processes with shared cellular pathways, such as cellular senescence, DNA damage repair, and metabolic reprogramming. However, the outcomes of these processes differ in terms of proliferation. U…
View article: Silver nanoparticles as next-generation antimicrobial agents: mechanisms, challenges, and innovations against multidrug-resistant bacteria
Silver nanoparticles as next-generation antimicrobial agents: mechanisms, challenges, and innovations against multidrug-resistant bacteria Open
The escalating prevalence of multidrug-resistant (MDR) bacteria presents a critical global health challenge, necessitating the urgent development of alternative antimicrobial strategies. Silver nanoparticles (AgNPs) have emerged as promisi…
View article: Bioinformation and Monitoring Technology for Environmental DNA Analysis: A Review
Bioinformation and Monitoring Technology for Environmental DNA Analysis: A Review Open
Environmental DNA (eDNA) analysis has emerged as a transformative tool in environmental monitoring, enabling non-invasive detection of species and microbial communities across diverse ecosystems. This study systematically reviews the role …
View article: Microfluidic Sensors for Micropollutant Detection in Environmental Matrices: Recent Advances and Prospects
Microfluidic Sensors for Micropollutant Detection in Environmental Matrices: Recent Advances and Prospects Open
The widespread and persistent occurrence of micropollutants—such as pesticides, pharmaceuticals, heavy metals, personal care products, microplastics, and per- and polyfluoroalkyl substances (PFAS)—has emerged as a critical environmental an…
View article: Sustainable synthesis of zinc oxide nanoparticles from Persicaria lapathifolia: versatile anticancer and antibacterial applications
Sustainable synthesis of zinc oxide nanoparticles from Persicaria lapathifolia: versatile anticancer and antibacterial applications Open
Colorectal cancer (CRC) is one of the most common cancers in the world and one of the leading causes of cancer mortality. In this study, zinc oxide nanoparticles (PlS-ZnO NPs) were synthesized eco-friendly using an aqueous extract from the…
View article: What is reproducibility in artificial intelligence and machine learning research?
What is reproducibility in artificial intelligence and machine learning research? Open
In the rapidly evolving fields of artificial intelligence (AI) and machine learning (ML), the reproducibility crisis underscores the urgent need for clear validation methodologies to maintain scientific integrity and encourage advancement.…
View article: A Comprehensive Meta‐Analysis on Antimicrobial Resistance Patterns of the Two Major <i>Brucella species</i> in Mediterranean Basin Countries
A Comprehensive Meta‐Analysis on Antimicrobial Resistance Patterns of the Two Major <i>Brucella species</i> in Mediterranean Basin Countries Open
Antimicrobial resistance (AMR) of brucellosis major causative bacteria Brucella abortus and Brucella melitensis is complicating human treatment strategies in the Mediterranean basin, where the disease was first reported and is still endemi…
View article: Fire under the ashes: A descriptive review on the prevalence of methicillin-resistant Staphylococcus aureus in the food supply chain
Fire under the ashes: A descriptive review on the prevalence of methicillin-resistant Staphylococcus aureus in the food supply chain Open
The aim of this review is to provide a comprehensive analysis of the prevalence and implications of methicillin-resistant Staphylococcus aureus (MRSA) within the food supply chain. Beginning with the molecular mechanisms of MRSA resistance…
View article: Association Between DEPDC5 and PNPLA3 Variants and the Risk of Hepatocellular Carcinoma in HCV-Infected Patients in Egypt
Association Between DEPDC5 and PNPLA3 Variants and the Risk of Hepatocellular Carcinoma in HCV-Infected Patients in Egypt Open
View article: Balancing the Scales: A Comprehensive Study on Tackling Class Imbalance in Binary Classification
Balancing the Scales: A Comprehensive Study on Tackling Class Imbalance in Binary Classification Open
Class imbalance in binary classification tasks remains a significant challenge in machine learning, often resulting in poor performance on minority classes. This study comprehensively evaluates three widely-used strategies for handling cla…
View article: Soil Actinobacteria Exhibit Metabolic Capabilities for Degrading the Toxic and Persistent Herbicide Metribuzin
Soil Actinobacteria Exhibit Metabolic Capabilities for Degrading the Toxic and Persistent Herbicide Metribuzin Open
Metribuzin, a widely used triazine herbicide, persists in agricultural soils and poses significant environmental pollution threats globally. The aim of this study was to investigate the biodegradation of metribuzin by actinobacterial strai…
View article: Antimicrobial Activity of Arthrospira platensis-Mediated Gold Nanoparticles against Streptococcus pneumoniae: A Metabolomic and Docking Study
Antimicrobial Activity of Arthrospira platensis-Mediated Gold Nanoparticles against Streptococcus pneumoniae: A Metabolomic and Docking Study Open
The emergence of antibiotic-resistant Streptococcus pneumoniae necessitates the discovery of novel therapeutic agents. This study investigated the antimicrobial potential of green-synthesized gold nanoparticles (AuNPs) fabricated using Art…
View article: Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature’s Toolkit for Environmental Sustainability
Microbial Immobilized Enzyme Biocatalysts for Multipollutant Mitigation: Harnessing Nature’s Toolkit for Environmental Sustainability Open
The ever-increasing presence of micropollutants necessitates the development of environmentally friendly bioremediation strategies. Inspired by the remarkable versatility and potent catalytic activities of microbial enzymes, researchers ar…
View article: Antimicrobial and Hemostatic Diatom Biosilica Composite Sponge
Antimicrobial and Hemostatic Diatom Biosilica Composite Sponge Open
The 3D nanopatterned silica shells of diatoms have gained attention as drug delivery vehicles because of their high porosity, extensive surface area, and compatibility with living organisms. Tooth extraction may result in various complicat…
View article: Bioinspired Synthesis and Characterization of Dual-Function Zinc Oxide Nanoparticles from Saccharopolyspora hirsuta: Exploring Antimicrobial and Anticancer Activities
Bioinspired Synthesis and Characterization of Dual-Function Zinc Oxide Nanoparticles from Saccharopolyspora hirsuta: Exploring Antimicrobial and Anticancer Activities Open
Microbial synthesis offers a sustainable and eco-friendly approach for nanoparticle production. This study explores the biogenic synthesis of zinc oxide nanoparticles (ZnO-NPs) utilizing the actinomycete Saccharopolyspora hirsuta (Ess_amA6…
View article: Biomimetic Antifungal Materials: Countering the Challenge of Multidrug-Resistant Fungi
Biomimetic Antifungal Materials: Countering the Challenge of Multidrug-Resistant Fungi Open
In light of rising public health threats like antifungal and antimicrobial resistance, alongside the slowdown in new antimicrobial development, biomimetics have shown promise as therapeutic agents. Multidrug-resistant fungi pose significan…
View article: Nanoengineered Silica-Based Biomaterials for Regenerative Medicine
Nanoengineered Silica-Based Biomaterials for Regenerative Medicine Open
The paradigm of regenerative medicine is undergoing a transformative shift with the emergence of nanoengineered silica-based biomaterials. Their unique confluence of biocompatibility, precisely tunable porosity, and the ability to modulate…
View article: Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin
Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin Open
Biomimetic materials have become a promising alternative in the field of tissue engineering and regenerative medicine to address critical challenges in wound healing and skin regeneration. Skin-mimetic materials have enormous potential to …
View article: What is Reproducibility in Artificial Intelligence and Machine Learning Research?
What is Reproducibility in Artificial Intelligence and Machine Learning Research? Open
In the rapidly evolving fields of Artificial Intelligence (AI) and Machine Learning (ML), the reproducibility crisis underscores the urgent need for clear validation methodologies to maintain scientific integrity and encourage advancement.…
View article: Biominerals and Bioinspired Materials in Biosensing: Recent Advancements and Applications
Biominerals and Bioinspired Materials in Biosensing: Recent Advancements and Applications Open
Inspired by nature’s remarkable ability to form intricate minerals, researchers have unlocked transformative strategies for creating next-generation biosensors with exceptional sensitivity, selectivity, and biocompatibility. By mimicking h…
View article: Baseline predictors of final infarct size in patients with ST elevation myocardial infarction undergoing primary PCI
Baseline predictors of final infarct size in patients with ST elevation myocardial infarction undergoing primary PCI Open
Background In patients with coronary artery disease, the presence and extent of myocardial scar determined from cardiac magnetic resonance (CMR) imaging have recognized associations with major adverse cardiac events. Therefore, in patients…
View article: Impact of COVID-19 on acquisitions of multi-drug-resistant organisms in a tertiary intensive care unit: A single center retrospective observational study
Impact of COVID-19 on acquisitions of multi-drug-resistant organisms in a tertiary intensive care unit: A single center retrospective observational study Open
Background: The coronavirus disease (COVID-19) has resulted in more than 6 million deaths worldwide since it was identified in 2019, resulting in significant morbidity and mortality. The impact of COVID-19 on the acquisition of multi-drug-…
View article: Density-Based Topology Optimization of High-Fidelity Fluid-Structure Interaction Problems with Large Deformations
Density-Based Topology Optimization of High-Fidelity Fluid-Structure Interaction Problems with Large Deformations Open
The application of modern topology optimization techniques to single physics systems has seen great advances in the last three decades. However, the application of these tools to sophisticated multiphysics systems such as fluid-structure i…
View article: A Study of Ophthalmic Problems Among Children Attending Ophthalmic Outpatient Clinic, Suez Canal University Hospital
A Study of Ophthalmic Problems Among Children Attending Ophthalmic Outpatient Clinic, Suez Canal University Hospital Open
View article: Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis Open
Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
View article: Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis Open
Purpose: Hepatocellular carcinoma (HCC) represents an increasing health problem in the United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60% of HCC patients; therefore, the identification o…
View article: Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis Open
Supplementary Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
View article: Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis
Data from Detection of Hepatocellular Carcinoma Using Glycomic Analysis Open
Purpose: Hepatocellular carcinoma (HCC) represents an increasing health problem in the United States. Serum α-fetoprotein, the currently used clinical marker, is elevated in only ∼60% of HCC patients; therefore, the identification o…
View article: On the Calculation of the Brinkman Penalization Term in Density-Based Topology Optimization of Fluid-Dependent Problems
On the Calculation of the Brinkman Penalization Term in Density-Based Topology Optimization of Fluid-Dependent Problems Open
In topology optimization of fluid-dependent problems, there is a need to interpolate within the design domain between fluid and solid in a continuous fashion. In density-based methods, the concept of inverse permeability in the form of a v…
View article: Tailored Functionalized Protein Nanocarriers for Cancer Therapy: Recent Developments and Prospects
Tailored Functionalized Protein Nanocarriers for Cancer Therapy: Recent Developments and Prospects Open
Recently, the potential use of nanoparticles for the targeted delivery of therapeutic and diagnostic agents has garnered increased interest. Several nanoparticle drug delivery systems have been developed for cancer treatment. Typically, pr…