Doha A. Mohamed
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View article: Cardamom extract: An effective weapon in prevention of cardiorenal syndrome induced in rats by cisplatin and high-fat diet
Cardamom extract: An effective weapon in prevention of cardiorenal syndrome induced in rats by cisplatin and high-fat diet Open
BACKGROUND Overnutrition and unhealthy dietary habits are established risk factors for cardiovascular and renal diseases, which may lead to the development of cardiorenal syndrome (CRS). AIM To evaluate the cardiorenal protective potential…
View article: Cardio-Protective Effects of Microencapsulated Probiotic and Synbiotic Supplements on a Myocardial Infarction Model Through the Gut–Heart Axis
Cardio-Protective Effects of Microencapsulated Probiotic and Synbiotic Supplements on a Myocardial Infarction Model Through the Gut–Heart Axis Open
Myocardial infarction (MI) is an inflammatory disease responsible for approximately 75% of sudden cardiac deaths. In this study, we aimed to evaluate the cardio-protective influence of microencapsulated probiotic and synbiotic dietary supp…
View article: Persea americana Peel: A Promising Source of Nutraceutical for the Mitigation of Cardiovascular Risk in Arthritic Rats Through the Gut–Joint Axis
Persea americana Peel: A Promising Source of Nutraceutical for the Mitigation of Cardiovascular Risk in Arthritic Rats Through the Gut–Joint Axis Open
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterized by the inflammation of synovial fluid. The incidence of cardiovascular diseases (CVDs) is increasing in RA patients. This research is the first report to …
View article: Dietary supplements for prevention of Alzheimer's disease: <i>In vivo</i> and <i>in silico</i> molecular docking studies.
Dietary supplements for prevention of Alzheimer's disease: <i>In vivo</i> and <i>in silico</i> molecular docking studies. Open
The present study concluded that all DS enhanced cholinergic neurotransmission, reduced inflammation, and improved oxidative stress status by impacting the expression of GSK3β, Akt, and APP genes. Rosmarinic acid and β-sitosterol showed pr…
View article: Obesity as Inducer of Cognitive Function Decline via Dysbiosis of Gut Microbiota in Rats
Obesity as Inducer of Cognitive Function Decline via Dysbiosis of Gut Microbiota in Rats Open
Diet-induced obesity is a global phenomenon that affects the population worldwide with manifestations at both the phenotypic and genotypic levels. Cognitive function decline is a major global health challenge. The relation between obesity …
View article: Effect of Carissa macrocarpa (Eckl.) A. DC. aerial parts on some non-communicable diseases: in vitro study and HPLC-QTOF/MS-MS analysis
Effect of Carissa macrocarpa (Eckl.) A. DC. aerial parts on some non-communicable diseases: in vitro study and HPLC-QTOF/MS-MS analysis Open
Carissa species are evergreen plants that have long been employed in treating different diseases by traditional healers in many cultures. Carissa macrocarpa (Eckl.) A. DC. known as Natal plum is characterized by bright red, edible, plum-sh…
View article: Sourdough bread as nutritional intervention tool for improvement of cognitive dysfunction in diabetic rats
Sourdough bread as nutritional intervention tool for improvement of cognitive dysfunction in diabetic rats Open
Background The current research targeted to study the impact of nutritional intervention by two sourdough breads in improvement of cognitive dysfunction in diabetic rats. Methods Type-2 diabetes was induced in rats by Streptozotocin-Nicoti…
View article: Comparative Histological Study of the Possible Protective Effect of Valsartan Versus Dexamethasone On Cyclophosphamide-Induced Lung Injury in Adult Male Albino Rat
Comparative Histological Study of the Possible Protective Effect of Valsartan Versus Dexamethasone On Cyclophosphamide-Induced Lung Injury in Adult Male Albino Rat Open
Introduction: Interstitial lung diseases are groups of chronic lung diseases characterized by inflammation and fibrosis. Aim of work: The present study was performed to evaluate the possible protective effect of valsartan versus dexamethas…
View article: Potential impacts of edible coatings fortified by Moringa and /or Cedar extracts on quality and shelf life of chilled turkey fillets
Potential impacts of edible coatings fortified by Moringa and /or Cedar extracts on quality and shelf life of chilled turkey fillets Open
Edible coatings offer a great potential to support sustainable food production by lowering packaging waste, extending product shelf life, and actively preserving food quality. Its application is becoming an increasing focus of research wit…
View article: Effects of Copper oxide nanoparticles on productive performance of broiler chickens under climate change conditions
Effects of Copper oxide nanoparticles on productive performance of broiler chickens under climate change conditions Open
This study aimed to investigate the effects of green Nano-Copper oxide (Nano-CuO) on growth performance, and serum biochemistry of broiler chickens. A total of 96One-day old broiler chickens were randomly distributed into two equal treatme…
View article: Study of Sub-acute Toxic Effects of Bisphenol A on Blood and Large Intestine and the Possible Protective Effect of Taurine in Adult Male Albino Rats
Study of Sub-acute Toxic Effects of Bisphenol A on Blood and Large Intestine and the Possible Protective Effect of Taurine in Adult Male Albino Rats Open
Background: Bisphenol A (BPA) is a plastic toxin widely used in manufacturing of plastic containers.It is known to produce a variety of toxic effects on body functions weight organic compound in living organisms.Aim of the work: This study…
View article: Green synthesis of copper oxide nanoparticles in broiler nutrition: Present perspectives and strategic future in climate change conditions
Green synthesis of copper oxide nanoparticles in broiler nutrition: Present perspectives and strategic future in climate change conditions Open
Under tropical and subtropical climates, global warming and climate change have a negative impact on the output of cattle and poultry. In hot temperature zones, heat stress is one of the most important stressors affecting chicken productiv…
View article: Anti-Obesity Evaluation of Averrhoa carambola L. Leaves and Assessment of Its Polyphenols as Potential α-Glucosidase Inhibitors
Anti-Obesity Evaluation of Averrhoa carambola L. Leaves and Assessment of Its Polyphenols as Potential α-Glucosidase Inhibitors Open
Averrhoa carambola L. is reported for its anti-obese and anti-diabetic activities. The present study aimed to investigate its aqueous methanol leaf extract (CLL) in vivo anti-obese activity along with the isolation and identification of bi…
View article: Hepatorenal Protective Effects of Sesame Seeds Oil, Flaxseed Oil and their Mixture against Methotrexate Toxicity in Rats
Hepatorenal Protective Effects of Sesame Seeds Oil, Flaxseed Oil and their Mixture against Methotrexate Toxicity in Rats Open
Background: Methotrexate (MTX) is an anti-metabolite drug used in the treatment of many cancers and autoimmune diseases. Methods: This study investigated the protective effect of flaxseed oil, sesame seed oil, and their mixture on the MTX-…
View article: Chia seeds oil enriched with phytosterols and mucilage as a cardioprotective dietary supplement towards inflammation, oxidative stress, and dyslipidemia
Chia seeds oil enriched with phytosterols and mucilage as a cardioprotective dietary supplement towards inflammation, oxidative stress, and dyslipidemia Open
Introduction: Non-communicable diseases are a cluster of metabolic diseases, which include type-2 diabetes, cancer, and cardiovascular diseases (CVDs). The aim of the current research was to incorporate dietary fibers (mucilage) and phytos…
View article: Characterization of stirred yoghurt enriched with probiotics and beetroot and its therapeutic potential in experimental type 2 diabetes [pdf]
Characterization of stirred yoghurt enriched with probiotics and beetroot and its therapeutic potential in experimental type 2 diabetes [pdf] Open
This study suggests that stirred yoghurt enriched with probiotics and fortified with beetroot have therapeutic potential for type 2 diabetes.
View article: Characterization of stirred yoghurt enriched with probiotics and beetroot and its therapeutic potential in experimental type 2 diabetes
Characterization of stirred yoghurt enriched with probiotics and beetroot and its therapeutic potential in experimental type 2 diabetes Open
Type-2 diabetes is the most prevalent metabolic disease, which calls for researchers to find many natural products that are effective in fighting diabetes and its complications.Stirred yoghurt samples were prepared, enriched with probiotic…
View article: Ameliorative Effect of Probiotic-Fermented Milk and Costus Extract in Alzheimer’s Disease Model Induced by D-Galactose and Aluminum Chloride
Ameliorative Effect of Probiotic-Fermented Milk and Costus Extract in Alzheimer’s Disease Model Induced by D-Galactose and Aluminum Chloride Open
Alzheimer's disease (AD) is a neurodegenerative disease associated with memory and cognitive dysfunction and is the main reason of dementia worldwide.The present research aimed to evaluate the protective effect of administration of probiot…
View article: Protective effect of dietary supplements against streptozotocin-induced Alzheimer’s disease in mice
Protective effect of dietary supplements against streptozotocin-induced Alzheimer’s disease in mice Open
Introduction: Alzheimer’s disease (AD) is a neurodegenerative problem that is increased progressively due to the increment of aging worldwide. Phytochemicals play an important role in the protection from neurodegeneration. The present stud…
View article: Antioxidant, anti-cancer and anti-arthritic activities of acetogenin-rich extract of avocado pulp
Antioxidant, anti-cancer and anti-arthritic activities of acetogenin-rich extract of avocado pulp Open
Avocado is an oil-rich fruit pleasant organoleptic characteristic, high nutritional value and health benefits due to its content of bioactive molecules.The objective of the current study was assessment of the antioxidant, anti-cancer and a…
View article: Cardioprotective potency of anthocyanin-rich extract of red cabbage against isoproterenol-induced myocardial infarction in experimental animals
Cardioprotective potency of anthocyanin-rich extract of red cabbage against isoproterenol-induced myocardial infarction in experimental animals Open
Evaluation of cardioprotective effects of Parkia biglobosa (Jacq. Benth) Mimosaceae stem barkAdi K., Metowogo K., Mouzou A., Lawson-Evi P., Eklu-Gadegbeku K., Agbonon A., Lamboni C., Essien K., Aklikokou K., Gbeassor M.
View article: Effect of Soybean on Bone Health and Some Metabolic Parameters in Postmenopausal Egyptian Women
Effect of Soybean on Bone Health and Some Metabolic Parameters in Postmenopausal Egyptian Women Open
Introduction: Great concern has been raised recently concerning the therapeutic impact of soybean. The present study aims to investigate the effects of soybean on bone health and metabolic parameters in postmenopausal women. Methods: In th…
View article: Spirulina-Enriched Pasta as Functional Food Rich in Protein and Antioxidant
Spirulina-Enriched Pasta as Functional Food Rich in Protein and Antioxidant Open
Functional foods are considered foods that have a beneficial impact when ingestion. The present work aims to prepare functional food in the form of pasta rich in antioxidants and protein by enrichment with different Spirulina levels (SP). …
View article: Amelioration of oxidative stress, inflammation and liver function by nutraceuticals in rat model of hepatic cancer initiation induced by N-nitrosodiethylamine
Amelioration of oxidative stress, inflammation and liver function by nutraceuticals in rat model of hepatic cancer initiation induced by N-nitrosodiethylamine Open
Introduction: Nutraceuticals might serve as protective agent against liver cancer induced by pro-cancerous chemicals that initiate high oxidative stress, inflammation and affect DNA integrity. The aim of the present research was to study t…
View article: Utilization of Grape and Apricot Fruits By-products as Cheap Source for Biologically Active Compounds for Health Promotion
Utilization of Grape and Apricot Fruits By-products as Cheap Source for Biologically Active Compounds for Health Promotion Open
The present study aims to evaluate the antioxidant and anti-cancer activities of nutraceuticals prepared from apricot kernel and grape seeds extracts.Different bioactive compounds were determined in the prepared nutraceuticals (total pheno…
View article: Nutrient and Sensory Metabolites Profiling of Averrhoa Carambola L. (Starfruit) in the Context of Its Origin and Ripening Stage by GC/MS and Chemometric Analysis
Nutrient and Sensory Metabolites Profiling of Averrhoa Carambola L. (Starfruit) in the Context of Its Origin and Ripening Stage by GC/MS and Chemometric Analysis Open
Averrhoa carambola L. is a tropical tree with edible fruit that grows at different climatic conditions. Despite its nutritive value and reported health benefits, it is a controversial fruit owing to its rich oxalate content. The present st…
View article: Rice bran as source of nutraceuticals for management of cardiovascular diseases, cardio-renal syndrome and hepatic cancer
Rice bran as source of nutraceuticals for management of cardiovascular diseases, cardio-renal syndrome and hepatic cancer Open
Introduction: The interrelation between cardiovascular diseases (CVDs) and renal dysfunction and the beneficial role of nutraceuticals are worthy to be studied. Nutraceuticals with anticancer effects are gaining great importance. The aim o…