Mohamed Ghalwash
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View article: Integrative Weaning Index as a Predictor of Successful Weaning from Mechanical Ventilation
Integrative Weaning Index as a Predictor of Successful Weaning from Mechanical Ventilation Open
View article: The effect of a proposed unit in science based on PISA standards in developing life problem-solving skills among Prep school students
The effect of a proposed unit in science based on PISA standards in developing life problem-solving skills among Prep school students Open
The current study aimed to identify life problem-solving skills that could be cultivated among middle school students, and to develop these skills through the implementation of a proposed unit within the science curriculum, aligning with t…
View article: Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles
Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles Open
OBJECTIVE To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetes RESEARCH DESIGN AND METHODS The T1DI (Type 1 Diabetes Intelligence) study combined data from 1,845 genetically susceptible prospectively obser…
View article: Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles
Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles Open
Objective. To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetesResearch Design and Methods: Type 1 Diabetes Intelligence (T1DI) study combined data from 1845 genetically susceptible, prospect…
View article: Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles
Data-Driven Phenotyping of Presymptomatic Type 1 Diabetes Using Longitudinal Autoantibody Profiles Open
Objective. To characterize distinct islet autoantibody profiles preceding stage 3 type 1 diabetesResearch Design and Methods: Type 1 Diabetes Intelligence (T1DI) study combined data from 1845 genetically susceptible, prospect…
View article: STRUCTURAL AND FUNCTIONAL CHANGES IN THE KIDNEYS IN AN ISOLATED POPULATION OF GERBILLUS GERBILLUS IN THE EGYPTIAN NILE DELTA
STRUCTURAL AND FUNCTIONAL CHANGES IN THE KIDNEYS IN AN ISOLATED POPULATION OF GERBILLUS GERBILLUS IN THE EGYPTIAN NILE DELTA Open
View article: Explanation Ontology: A general-purpose, semantic representation for supporting user-centered explanations
Explanation Ontology: A general-purpose, semantic representation for supporting user-centered explanations Open
In the past decade, trustworthy Artificial Intelligence (AI) has emerged as a focus for the AI community to ensure better adoption of AI models, and explainable AI is a cornerstone in this area. Over the years, the focus has shifted from b…
View article: Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity
Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity Open
OBJECTIVE To estimate the risk of progression to stage 3 type 1 diabetes based on varying definitions of multiple islet autoantibody positivity (mIA). RESEARCH DESIGN AND METHODS Type 1 Diabetes Intelligence (T1DI) is a combined prospectiv…
View article: Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity
Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity Open
OBJECTIVE: To estimate risk of progression to stage 3 type 1 diabetes based on varying definition of multiple islet autoantibody positivity (mIA). RESEARCH DESIGN AND METHODS: T1DI is a combined prospective dataset of children from Finl…
View article: Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity
Refining the Definition of Stage 1 Type 1 Diabetes: An Ontology-Driven Analysis of the Heterogeneity of Multiple Islet Autoimmunity Open
OBJECTIVE: To estimate risk of progression to stage 3 type 1 diabetes based on varying definition of multiple islet autoantibody positivity (mIA). RESEARCH DESIGN AND METHODS: T1DI is a combined prospective dataset of children from Finl…
View article: Informing clinical assessment by contextualizing post-hoc explanations of risk prediction models in type-2 diabetes
Informing clinical assessment by contextualizing post-hoc explanations of risk prediction models in type-2 diabetes Open
View article: Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: a prospective cohort study
Islet autoantibody screening in at-risk adolescents to predict type 1 diabetes until young adulthood: a prospective cohort study Open
View article: A comparative hematological, biochemical and renal histological study of Gerbillus pyramidum, Mus musculus and Rattus norvegicus from three different regions in Egypt
A comparative hematological, biochemical and renal histological study of Gerbillus pyramidum, Mus musculus and Rattus norvegicus from three different regions in Egypt Open
View article: Interpretable Stratification for Chronic Kidney Disease Progression Based on Time to Event Analysis.
Interpretable Stratification for Chronic Kidney Disease Progression Based on Time to Event Analysis. Open
In Chronic Kidney Disease (CKD), kidneys are damaged and lose their ability to filter blood, leading to a plethora of health consequences that end up in dialysis. Despite its prevalence, CKD goes often undetected at early stages. In order …
View article: Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study
Two-age islet-autoantibody screening for childhood type 1 diabetes: a prospective cohort study Open
View article: Human-centered explainability for life sciences, healthcare, and medical informatics
Human-centered explainability for life sciences, healthcare, and medical informatics Open
Rapid advances in artificial intelligence (AI) and availability of biological, medical, and healthcare data have enabled the development of a wide variety of models. Significant success has been achieved in a wide range of fields, such as …
View article: Kidney Function and Structure, Oxidative Stress and Immunohistochemical Expression of Gerbillus gerbillus from Two Different Habitats in Egypt
Kidney Function and Structure, Oxidative Stress and Immunohistochemical Expression of Gerbillus gerbillus from Two Different Habitats in Egypt Open
Mammals from arid habitats have greater relative medullary thickness and maximum urine concentration as compared with those from mesic habitats. The Egyptian lesser gerbil, Gerbillus gerbillus (Olivier, 1801), inhabits coastal dunes of whi…
View article: Improving the Computational Complexity of the COOL Screening Tool
Improving the Computational Complexity of the COOL Screening Tool Open
Autoimmune disorder, such as celiac disease and type 1 diabetes, is a condition in which the immune system attacks body tissues by mistake. This might be triggered by abnormality in the development of biomarkers such as autoantibodies, whi…
View article: Data-Driven Disease Progression Modeling
Data-Driven Disease Progression Modeling Open
This chapter provides a comprehensive overview to data driven disease progression modeling techniques. It adopts a broad approach to disease progression, focusing on all computational methods able to model any temporal aspects of disease p…
View article: Effect of Self-Care Practice Health Educational Program for Patients on Urinary Tract Infection Recurrence
Effect of Self-Care Practice Health Educational Program for Patients on Urinary Tract Infection Recurrence Open
View article: Leveraging Clinical Context for User-Centered Explainability: A Diabetes Use Case
Leveraging Clinical Context for User-Centered Explainability: A Diabetes Use Case Open
Academic advances of AI models in high-precision domains, like healthcare, need to be made explainable in order to enhance real-world adoption. Our past studies and ongoing interactions indicate that medical experts can use AI systems with…
View article: Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S.
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S. Open
OBJECTIVE: To combine prospective cohort studies, by including HLA harmonization, and to estimate risk of islet autoimmunity and progression to clinical diabetes. RESEARCH DESIGN AND METHODS: Prospective cohorts in Finland, Germany, Sweden…
View article: Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S.
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S. Open
OBJECTIVE: To combine prospective cohort studies, by including HLA harmonization, and to estimate risk of islet autoimmunity and progression to clinical diabetes. RESEARCH DESIGN AND METHODS: Prospective cohorts in Finland, Germany, Sweden…
View article: Disease Progression Modeling Workbench 360
Disease Progression Modeling Workbench 360 Open
In this work we introduce Disease Progression Modeling workbench 360 (DPM360) opensource clinical informatics framework for collaborative research and delivery of healthcare AI. DPM360, when fully developed, will manage the entire modeling…
View article: Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S.
Islet Autoimmunity and HLA Markers of Presymptomatic and Clinical Type 1 Diabetes: Joint Analyses of Prospective Cohort Studies in Finland, Germany, Sweden, and the U.S. Open
OBJECTIVE To combine prospective cohort studies, by including HLA harmonization, and estimate risk of islet autoimmunity and progression to clinical diabetes. RESEARCH DESIGN AND METHODS For prospective cohorts in Finland, Germany, Sweden,…
View article: Blending Knowledge in Deep Recurrent Networks for Adverse Event Prediction at Hospital Discharge
Blending Knowledge in Deep Recurrent Networks for Adverse Event Prediction at Hospital Discharge Open
Deep learning architectures have an extremely high-capacity for modeling complex data in a wide variety of domains. However, these architectures have been limited in their ability to support complex prediction problems using insurance clai…
View article: Blending Knowledge in Deep Recurrent Networks for Adverse Event\n Prediction at Hospital Discharge
Blending Knowledge in Deep Recurrent Networks for Adverse Event\n Prediction at Hospital Discharge Open
Deep learning architectures have an extremely high-capacity for modeling\ncomplex data in a wide variety of domains. However, these architectures have\nbeen limited in their ability to support complex prediction problems using\ninsurance c…
View article: Impact of Clinical and Genomic Factors on SARS-CoV2 Disease Severity
Impact of Clinical and Genomic Factors on SARS-CoV2 Disease Severity Open
The SARS-CoV2 virus behind the COVID-19 pandemic is manifesting itself in different ways among infected people. While many are experiencing mild flue-like symptoms or are even remaining asymptomatic after infection, the virus has also led …
View article: Phenotypical ontology driven framework for multi-task learning
Phenotypical ontology driven framework for multi-task learning Open
Despite the large number of patients in Electronic Health Records (EHRs), the subset of usable data for modeling outcomes of specific phenotypes are often imbalanced and of modest size. This can be attributed to the uneven coverage of medi…
View article: Simulating Screening for Risk of Childhood Diabetes: The Collaborative Open Outcomes tooL (COOL).
Simulating Screening for Risk of Childhood Diabetes: The Collaborative Open Outcomes tooL (COOL). Open
The Collaborative Open Outcomes tooL (COOL) is a novel, highly configurable application to simulate, evaluate and compare potential population-level screening schedules. Its first application is type 1 diabetes (T1D) screening, where known…