Mohamed M. Elsebaei
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View article: SYNTHESIS OF SOME NEW PYRAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS
SYNTHESIS OF SOME NEW PYRAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS Open
View article: Phenyltriazole-based sulfonamides: novel dual-target agents against MRSA biofilms and resistant pathogens
Phenyltriazole-based sulfonamides: novel dual-target agents against MRSA biofilms and resistant pathogens Open
The advent of multidrug-resistant bacteria requires the continuous development of new antimicrobial agents.
View article: Development of carboximidamide small molecule nanogels as potent antimicrobial functional drug delivery systems
Development of carboximidamide small molecule nanogels as potent antimicrobial functional drug delivery systems Open
The escalating threat of multidrug-resistant (MDR) bacterial infections necessitates innovative antimicrobial strategies with enhanced potency, selectivity, and pharmacokinetic profiles.
View article: SYNTHESIS OF NEW CHLOROQUINE DERIVATIVES FOR BIOLOGICAL STUDIES
SYNTHESIS OF NEW CHLOROQUINE DERIVATIVES FOR BIOLOGICAL STUDIES Open
View article: SYNTHESIS OF SOME NEW AZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS
SYNTHESIS OF SOME NEW AZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS Open
Antibiotic resistance is a growing global health threat and requires extensive research to combat this urgent problem. Phenylthiazoles, known for their diverse biological activities including anthelmintic, insecticidal, and antimicrobial p…
View article: Rational design and synthesis of novel phenyltriazole derivatives targeting MRSA cell wall biosynthesis
Rational design and synthesis of novel phenyltriazole derivatives targeting MRSA cell wall biosynthesis Open
Antimicrobial resistance in methicillin-resistant Staphylococcus aureus (MRSA) is a major global health challenge.
View article: Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies
Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by Docking Studies Open
Phenylpyrazolo[3,4-d]pyrimidine is considered a milestone scaffold known to possess various biological activities such as antiparasitic, antifungal, antimicrobial, and antiproliferative activities. In addition, the urgent need for selectiv…
View article: Development of pyrazolo[1,5-a]pyrimidine derivatives: Synthesis, anticancer activity and docking study
Development of pyrazolo[1,5-a]pyrimidine derivatives: Synthesis, anticancer activity and docking study Open
It has been revealed that scaffolds made from pyrazolo [1,5-a]pyrimidines exhibit valuable biological activities, particularly anti-proliferative efficacy and blocking CDK activity.Therefore, new derivatives of pyrazolo[1,5-a]pyrimidines 5…
View article: Review of: "Flavocillin: a potent TrxR and OATP inhibitor"
Review of: "Flavocillin: a potent TrxR and OATP inhibitor" Open
Potential competing interests: No potential competing
View article: DESIGN AND SYNTHESIS OF NOVEL TERREMIDE AND SULFONAIDES DERIVATIVES FOR PHARMACOLOGICAL EVALUATION
DESIGN AND SYNTHESIS OF NOVEL TERREMIDE AND SULFONAIDES DERIVATIVES FOR PHARMACOLOGICAL EVALUATION Open
Bacterial infections were first recorded back at 3000 B.C.E.Since then, there have been an enormous number of pandemics that hit the world.Countless doctors and researchers have been working on a definitive solution to exterminate all bact…
View article: DESIGN AND SYNTHESIS OF NOVEL TERREMIDE DERIVATIVES FOR PHARMACOLOGICAL EVALUATION
DESIGN AND SYNTHESIS OF NOVEL TERREMIDE DERIVATIVES FOR PHARMACOLOGICAL EVALUATION Open
View article: Peptidoglycan pathways: there are still more!
Peptidoglycan pathways: there are still more! Open
The discovery of 3rdand 4thgenerations of currently existing classes of antibiotics has not hindered bacterial resistance, which is escalating at an alarming global level.
View article: Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA)
Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA) Open
View article: Arylthiazole antibiotics targeting intracellular methicillin-resistant Staphylococcus aureus (MRSA) that interfere with bacterial cell wall synthesis
Arylthiazole antibiotics targeting intracellular methicillin-resistant Staphylococcus aureus (MRSA) that interfere with bacterial cell wall synthesis Open