Amany Mohamed Shalaby
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View article: Histological and Immunohistochemical Study of the Effect of Zinc Oxide Nanoparticles on the Adult Male Albino Rat`s Cerebellar Cortex and the Potential Ameliorative Effect of Mesenchymal Stem Cells derived from Bone Marrow
Histological and Immunohistochemical Study of the Effect of Zinc Oxide Nanoparticles on the Adult Male Albino Rat`s Cerebellar Cortex and the Potential Ameliorative Effect of Mesenchymal Stem Cells derived from Bone Marrow Open
View article: Evaluation of Some Prognostic Biomarkers in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma.
Evaluation of Some Prognostic Biomarkers in Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma. Open
HMSC is strongly associated with HR-HPV. The expression of VEGF, EGFR, BAX, hTERT, and ProExTMC is associated with aggressive malignant behavior, poor survival, and poor prognosis, making them novel prognostic biomarkers for tar…
View article: Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways.
Epstein-Barr Virus Promotes Tumorigenicity and Worsens Hodgkin Lymphoma Prognosis by Activating JAK/STAT and NF-κB Signaling Pathways. Open
Through the activation of JAK/STAT and NF-κB signaling pathways, EBV-positive CHL is associated with poor clinicopathological parameters, higher incidence of disease progression, relapse, and poor overall survival. A preprint of this manus…
View article: Enhancers of cancer stem cells and epithelial–mesenchymal transition: Lin28, MUC1, and lipocalin-2 as a new prognostic axis in classical invasive lobular carcinoma of the breast
Enhancers of cancer stem cells and epithelial–mesenchymal transition: Lin28, MUC1, and lipocalin-2 as a new prognostic axis in classical invasive lobular carcinoma of the breast Open
Breast carcinoma is one of the most common causes of cancer-related mortality among women worldwide. The primary objective of the present study was to eva-luate the expression of the epithelial-mesenchymal transition (EMT)-related markers …
View article: Effect of Aromatase Inhibitor Letrozole on the Placenta of Adult Albino Rats: A Histopathological, Immunohistochemical, and Biochemical Study.
Effect of Aromatase Inhibitor Letrozole on the Placenta of Adult Albino Rats: A Histopathological, Immunohistochemical, and Biochemical Study. Open
Letrozole inhibited the expression of ER and PR in rat placenta. It interrupted stimulatory vascular signals causing significant apoptosis and placental vascular dysfunction. Letrozole in an equivalent human daily dose of 10 mg caused a hi…
View article: Role of Neoadjuvant Chemotherapy Followed by Interval Cyto-Reductive Surgery in Reducing Progression and Recurrence of Patients with Advanced Endometrial Cancer
Role of Neoadjuvant Chemotherapy Followed by Interval Cyto-Reductive Surgery in Reducing Progression and Recurrence of Patients with Advanced Endometrial Cancer Open
Background: Cytoreductive surgery (CRS) roles in advanced EC are not fully defined and there are few published data about role of neoadjuvant chemotherapy followed by cytoreductive surgery in advanced endometrioid endometrial adenocarcinom…
View article: The Prognostic Value of Cancer Stem Cell Marker, Cluster of Differentiation 133 Expression in Stage III Colorectal Carcinoma
The Prognostic Value of Cancer Stem Cell Marker, Cluster of Differentiation 133 Expression in Stage III Colorectal Carcinoma Open
Background: Colorectal cancer (CRC) is the 3 rd most prevalent diagnosed cancer and the 4 th leading cause of cancer-related deaths globally.Nodal staging is significantly more essential in rectal cancer that detects most the therapy optio…
View article: EBV promotes tumorigenicity and worsens the prognosis of Hodgkin lymphoma through the expression of survival enhancing proteins by activating the JAK / STAT and NF-kB signaling pathways. (A comparative study between EBV positive and negative Hodgkin lymphoma)
EBV promotes tumorigenicity and worsens the prognosis of Hodgkin lymphoma through the expression of survival enhancing proteins by activating the JAK / STAT and NF-kB signaling pathways. (A comparative study between EBV positive and negative Hodgkin lymphoma) Open
Background Epstein-Barr virus (EBV) is involved in 40% of all Hodgkin's lymphoma (HL) cases. EBV produces epigenetic alterations in the host genome that decrease the expression of proapoptotic proteins and activate the expression of surviv…
View article: Evaluation of Different Doses of the Aromatase Inhibitor Letrozole for the Treatment of Ectopic Pregnancy and Its Effect on Villous Trophoblastic Tissue
Evaluation of Different Doses of the Aromatase Inhibitor Letrozole for the Treatment of Ectopic Pregnancy and Its Effect on Villous Trophoblastic Tissue Open
Letrozole, an aromatase inhibitor, has recently been introduced as a favorable medical treatment for ectopic pregnancy. We aimed at evaluating the effects of different doses of letrozole for termination of ectopic pregnancy and study their…
View article: ANTIMICROBIAL RESISTANCE AND VIRULENCE-ASSOCIATED GENES OF AER-OMONADS ISOLATED FROM LAKE MANZALA WATER AND WILD NILE TILAPIA: IMPLICATIONS TO PUBLIC HEALTH AND THE LAKE MICROBIAL COMMUNITY
ANTIMICROBIAL RESISTANCE AND VIRULENCE-ASSOCIATED GENES OF AER-OMONADS ISOLATED FROM LAKE MANZALA WATER AND WILD NILE TILAPIA: IMPLICATIONS TO PUBLIC HEALTH AND THE LAKE MICROBIAL COMMUNITY Open
This study was conducted to investigate the prevalence, antimicrobial susceptibility, and molecular characterization of Aeromonas spp. from wild Nile tilapia from Lake Manzala and the lake water. Swabs from the surface, gills, and internal…
View article: High-risk human papillomavirus enhances the expression of COX-2 VEGF, EGFR, ProEx-C, and TERT proteins inhuman papillomavirus-related multiphenotypic sinonasal carcinoma through activation of PI3K/Akt, pRb, and TERTsignalling pathways
High-risk human papillomavirus enhances the expression of COX-2 VEGF, EGFR, ProEx-C, and TERT proteins inhuman papillomavirus-related multiphenotypic sinonasal carcinoma through activation of PI3K/Akt, pRb, and TERTsignalling pathways Open
Human papillomavirus (HPV)-related multiphenotypic sinonasal carcinoma (HMSC) is a new type of sinonasal tumour that frequently drops out of accurate diagnosis. Human papillomavirus related multiphenotypic sinonasal carcinoma was previousl…
View article: 90 Penetrating Abdominal Trauma: Comperative Study Between Operative and Conservative Management
90 Penetrating Abdominal Trauma: Comperative Study Between Operative and Conservative Management Open
Aim to Assess the feasibility and safety of selective non-operative management in penetrating abdominal injuries and to identify a protocol for selection of patient’s candidates for non-operative management. Method In this comparative stud…
View article: The Diagnostic and Prognostic Roles of Combined Expression of Novel Biomarkers in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC); An Immunohistochemical Study
The Diagnostic and Prognostic Roles of Combined Expression of Novel Biomarkers in Lung Adenocarcinoma (LUAD) and Lung Squamous Cell Carcinoma (LUSC); An Immunohistochemical Study Open
The combination of biomarkers of CLCA2, SPATS2, ST6GALNAC1, and Adipophilin may lead to an appropriate subtyping of lung cancer and reaching accurate diagnosis with the highest sensitivity and specificity.
View article: The Effect of Induced Diabetes Mellitus on the Cerebellar Cortex of Adult Male Rat and the Possible Protective Role of Oxymatrine: A Histological, Immunohistochemical and Biochemical Study
The Effect of Induced Diabetes Mellitus on the Cerebellar Cortex of Adult Male Rat and the Possible Protective Role of Oxymatrine: A Histological, Immunohistochemical and Biochemical Study Open
Diabetes mellitus (DM) represents a widespread metabolic disease with a well-known neurotoxicity in both central and peripheral nervous systems. Oxymatrine is a traditional Chinese herbal medicine that has various pharmacological activitie…
View article: Impact of Crude Methanolic Extract of Melia azedarach L. on The Fecundity and The Cuticle of The Adult House Fly, Musca domestica Macq
Impact of Crude Methanolic Extract of Melia azedarach L. on The Fecundity and The Cuticle of The Adult House Fly, Musca domestica Macq Open
The house fly Musca vicina Macq is found in human habitat.Insecticides usually destroy the natural enemies of a given pest more than the pest itself.The penetration of substances, through the integument of a living insect, is restricted by…
View article: Prognostic and clinicopathological implications of expression of Beclin-1 and hypoxia-inducible factor 1α in serous ovarian carcinoma: an immunohistochemical study
Prognostic and clinicopathological implications of expression of Beclin-1 and hypoxia-inducible factor 1α in serous ovarian carcinoma: an immunohistochemical study Open
Serous ovarian carcinoma (SOC) is an ovarian cancer with a high fatality rate. Therefore, a lot of researchers have tried to identify novel prognostic biomarkers which might improve the patient prognosis. The aims of the study were to dete…
View article: The Effect of 5-Fluorouracil on the tongue mucosa of adult male albino rat and the possible protective role of melatonin: A light and scanning electron microscopic study
The Effect of 5-Fluorouracil on the tongue mucosa of adult male albino rat and the possible protective role of melatonin: A light and scanning electron microscopic study Open
Background:5-Fluorouracil(5-FU)is a common anti-tumor drug that is used in the management of different forms of malignancies. Mucosal inflammation of the oral cavity is the most common adverse effect of its administration. Melatonin has va…
View article: TERT promoter mutation and proEx C are useful as a screening tool to predict the malignant behavior of thyroid tumors of uncertain malignant potential
TERT promoter mutation and proEx C are useful as a screening tool to predict the malignant behavior of thyroid tumors of uncertain malignant potential Open
Gray zone thyroid tumors for which benignity or malignancy cannot be assessed are constantly increasing and accurate prediction of their malignant behavior is vital to avoid both violent surgical intervention for benign tumors and lax trea…
View article: Vestibular Assessment in Chronic Obstructive Pulmonary Disease Patients
Vestibular Assessment in Chronic Obstructive Pulmonary Disease Patients Open
Background: Chronic Obstructive Pulmonary Disorder (COPD) is a common preventable and treatable disease which is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammator…
View article: The Effects of Zanzalacht on the Gonotrophic cycle of the Adult House fly Musca Domestica
The Effects of Zanzalacht on the Gonotrophic cycle of the Adult House fly Musca Domestica Open
Melia azedarach extract were applied by feeding the adult female flies on diets mixed with the extracts at different doses. The concentrations of Melia azedarach utilized were 1.8, 2.4 and 3.6%. The gonotrophic cycles of length of 90, 753,…
View article: Studies on Amoebicidal Agents : II. Synthesis And Amoebicidal Activity of Toluene-2:4-Bis-Sulfon-N-Anilides
Studies on Amoebicidal Agents : II. Synthesis And Amoebicidal Activity of Toluene-2:4-Bis-Sulfon-N-Anilides Open