Mohammad Hadi Imanieh
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View article: Molecular Characterization of Wilson’s Disease in Liver Transplant Patients: A Five-Year Single-Center Experience in Iran
Molecular Characterization of Wilson’s Disease in Liver Transplant Patients: A Five-Year Single-Center Experience in Iran Open
Background/Objectives: Wilson’s disease (WD) is an autosomal recessive disorder characterized by pathological copper accumulation, primarily in the liver and brain. Severe hepatic involvement can be effectively treated with liver transplan…
View article: Pediatric Gastric Adenocarcinoma in the Setting of Celiac Disease: A Rare and Insightful Case Report
Pediatric Gastric Adenocarcinoma in the Setting of Celiac Disease: A Rare and Insightful Case Report Open
Gastric adenocarcinoma is exceptionally rare in children, often presenting with nonspecific gastrointestinal (GI) symptoms. This case highlights the importance of considering malignancy in pediatric patients with celiac disease and poor di…
View article: Hepatic tumors in Iranian children: Characteristics and survival predictors
Hepatic tumors in Iranian children: Characteristics and survival predictors Open
The characteristics of pediatric hepatic tumors in our study were similar to those reported in most studies. Abdominal pain and distension and presence of HCC or jaundice were independent predictors of a poor prognosis.
View article: <scp>An</scp> Unusual Presentation of Tyrosinemia Type 1 in a Pediatric Patient: Case Report and Comprehensive Review
<span>An</span> Unusual Presentation of Tyrosinemia Type 1 in a Pediatric Patient: Case Report and Comprehensive Review Open
Tyrosinemia type 1 often manifests with liver, renal, or peripheral neuropathy disorders. Before therapies like nitisinone, management was limited to dietary modifications and liver transplantation. We present a 19‐month‐old girl who devel…
View article: Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients
Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients Open
Post-Liver transplantation (LT) survival rates stagnate, with biliary complications (BC) as a major cause of death. We analyzed longitudinal data with a median 19-month follow-up. BC was diagnosed with ultrasounds and MRCP. Missing data wa…
View article: Clinical spectrum and genetic variation of six patients with methylmalonic aciduria (MMA); a report from Iran
Clinical spectrum and genetic variation of six patients with methylmalonic aciduria (MMA); a report from Iran Open
View article: Four-Year Bacteriological Profile and Antibiotic Resistance Rate of Neonatal Blood Cultures in a Major Neonatal Intensive Care Unit (NICU) in Shiraz, Southwest Iran
Four-Year Bacteriological Profile and Antibiotic Resistance Rate of Neonatal Blood Cultures in a Major Neonatal Intensive Care Unit (NICU) in Shiraz, Southwest Iran Open
Background: Bacterial infections are the leading cause of death in newborns. The growing resistance of bacteria to antibiotics is a major concern. In this study, we identified isolates from blood cultures in the neonatal intensive care uni…
View article: Charting Unexplored Territories: ERCP Indications and Complications in Pediatric Patients; A Cross-Sectional Study from 2022 to 2023
Charting Unexplored Territories: ERCP Indications and Complications in Pediatric Patients; A Cross-Sectional Study from 2022 to 2023 Open
Background: There are ongoing concerns about the safety of endoscopic retrograde cholangiopancreatography (ERCP) in children, as recorded cases have shown complications. Objectives: The objective of this study is to investigate the indicat…
View article: Clinical Findings, Bacterial Agents, and Antibiotic Resistance in Children with Spontaneous Peritonitis in Southern Iran: An Academic Tertiary Referral Center's Experience.
Clinical Findings, Bacterial Agents, and Antibiotic Resistance in Children with Spontaneous Peritonitis in Southern Iran: An Academic Tertiary Referral Center's Experience. Open
Although third-generation cephalosporins are recommended as the primary antibiotic for the empirical treatment of SBP, the present study found high bacterial resistance. Finally, empirical therapy should be tailored to each region's bacter…
View article: A Comparison of the Effect of Kegel Exercises and Conventional Therapy versus Conventional Therapy Alone in the Treatment of Functional Constipation in Children: A Randomized Clinical Trial.
A Comparison of the Effect of Kegel Exercises and Conventional Therapy versus Conventional Therapy Alone in the Treatment of Functional Constipation in Children: A Randomized Clinical Trial. Open
Kegel exercise was an effective adjunctive treatment for pediatric functional constipation.Trial Registration Number: IRCT20230424057984N1.
View article: Large Volume Paracentesis in Patients with Liver Cirrhosis Temporarily Diminishes Blood Cell Count.
Large Volume Paracentesis in Patients with Liver Cirrhosis Temporarily Diminishes Blood Cell Count. Open
The findings of the present study showed that children with tense ascites who had large-volume paracentesis might experience a sharp drop in blood cell count after the procedure, which was a transient physiological condition.
View article: Identification of two Iranian siblings with cerebrotendinous xanthomatosis: a case report
Identification of two Iranian siblings with cerebrotendinous xanthomatosis: a case report Open
Background Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive lipid storage disorder that leads to multisystem involvement. It is caused by mutations in the CYP27A1 gene which encodes the mitochondrial enzyme sterol 27-hydr…
View article: Evaluation of Outcomes and Complications of Large Volume Paracentesis without Albumin and Coagulopathy Therapy in Pediatrics with Severe Ascites
Evaluation of Outcomes and Complications of Large Volume Paracentesis without Albumin and Coagulopathy Therapy in Pediatrics with Severe Ascites Open
Children having tense ascites with thrombocytopenia, prolonged PT, Child-Pugh class C, and encephalopathy can undergo large-volume paracentesis without any complication. Albumin administration before the procedure in patients with low leve…
View article: Family Physician Program in Fars Province: A Ten-year-old Journey in Iran.
Family Physician Program in Fars Province: A Ten-year-old Journey in Iran. Open
More than 50 years have passed since the first family physician programs were established around the world.
View article: Manifestation of leech infestation as severe gastrointestinal bleeding in a 3-year-old boy: a case report and review of the literature
Manifestation of leech infestation as severe gastrointestinal bleeding in a 3-year-old boy: a case report and review of the literature Open
View article: Questioning Diagnostic Value of Serum Matrix Metalloproteinase 7 for Biliary Atresia
Questioning Diagnostic Value of Serum Matrix Metalloproteinase 7 for Biliary Atresia Open
View article: Prevalence of COVID-19 in Children with Gastrointestinal Manifestations: A Cross-sectional Study of 184 Cases in 2020 - 2021
Prevalence of COVID-19 in Children with Gastrointestinal Manifestations: A Cross-sectional Study of 184 Cases in 2020 - 2021 Open
Background: The coronavirus disease 2019 (COVID-19) pandemic has affected human life for more than a year. COVID-19 is well known for its respiratory manifestations; however, other important symptoms help with its diagnosis. Although clini…
View article: A pathogenic variant of TULP3 causes renal and hepatic fibrocystic disease
A pathogenic variant of TULP3 causes renal and hepatic fibrocystic disease Open
Patient variants in Tubby Like Protein-3 (TULP3) have recently been associated with progressive fibrocystic disease in tissues and organs. TULP3 is a ciliary trafficking protein that links membrane-associated proteins to the intraflagellar…
View article: Thyroid Stimulating Hormone, T3 and T4 Population-based Reference Range and Children Prevalence of Thyroid Dysfunction: First Report from South of Iran
Thyroid Stimulating Hormone, T3 and T4 Population-based Reference Range and Children Prevalence of Thyroid Dysfunction: First Report from South of Iran Open
We found a statistically difference between hormone values younger and older than age 18 (P=≤0.01); therefore, it is not appropriate to use the same reference range for children younger than age 18 and adults. There was male predomi…
View article: Development of Bio-artificial Esophageal Tissue Engineering Utilization for Circumferential Lesion Transplantation: A Narrative Review.
Development of Bio-artificial Esophageal Tissue Engineering Utilization for Circumferential Lesion Transplantation: A Narrative Review. Open
The esophagus is the gastrointestinal tract's primary organ that transfers bolus into the stomach with peristaltic motion. Therefore, its lesions cause a significant disturbance in the nutrition and digestive system. Esophageal disease tre…
View article: An evaluation of ascitic calprotectin for diagnosis of ascitic fluid infection in children with cirrhosis
An evaluation of ascitic calprotectin for diagnosis of ascitic fluid infection in children with cirrhosis Open
View article: Post-transplant Lymphoproliferative Disorder in Pediatric Liver Transplantation: A Population-based Study from Shiraz, Iran
Post-transplant Lymphoproliferative Disorder in Pediatric Liver Transplantation: A Population-based Study from Shiraz, Iran Open
Background: This study aimed to determine the prevalence of post-transplant lymphoproliferative disorder (PTLD) based on the clinical and epidemiological characteristics of donors and pediatric transplant recipients. Methods: This cross-se…
View article: Public Trust in Healthcare System in Iran: A Rapid Assessment During the COVID-19 Epidemic in Iran
Public Trust in Healthcare System in Iran: A Rapid Assessment During the COVID-19 Epidemic in Iran Open
Background and aims: Public health policies and programs should be adapted to the level of public trust in the healthcare system, as an indicator of the public support level. Accordingly, the data about public trust level in the healthcare…
View article: Single Dose or Divided Dose of Polyethylene Glycol in Treatment of Pediatric Functional Constipation: A Randomized Clinical Trial
Single Dose or Divided Dose of Polyethylene Glycol in Treatment of Pediatric Functional Constipation: A Randomized Clinical Trial Open
BackgroundThis study aimed to compare different regimens of Polyethylene Glycol (PEG, single dose vs. divided dose) in the treatment of functional constipation among children aged 4-15 years.Materials and MethodsThis double-blind randomize…
View article: Evaluation of Validity and Efficiency of Diagnostic Criteria in Autoimmune Hepatitis in Children
Evaluation of Validity and Efficiency of Diagnostic Criteria in Autoimmune Hepatitis in Children Open
Our study is the first validation study of the new scoring system in diagnosing AIH, and further studies require verifying this scoring system.
View article: Author Correction: Clinical and genetic spectrum of glycogen storage disease in Iranian population using targeted gene sequencing
Author Correction: Clinical and genetic spectrum of glycogen storage disease in Iranian population using targeted gene sequencing Open
A total of the 15 pediatric patients were admitted to our hospital and referred for molecular genetic testing using TGS.Eight genes namely SLC37A4, AGL, GBE1, PYGL, PHKB, PGAM2, and PRKAG2 were detected to be responsible for the onset of t…
View article: Different Clinical Features of Celiac Disease in Children, Adolescents, and Adults; a Cross-sectional Study
Different Clinical Features of Celiac Disease in Children, Adolescents, and Adults; a Cross-sectional Study Open
BACKGROUND Celiac disease is a common disorder but there are few studies comparing the clinical features of the disease in adults, adolescents and children. METHODS Demographic and clinical characteristics of all patients with celiac disea…
View article: Pediatric liver and kidney transplantation in the era of COVID-19: a follow-up study from a tertiary referral center in Iran
Pediatric liver and kidney transplantation in the era of COVID-19: a follow-up study from a tertiary referral center in Iran Open
View article: Clinical and genetic spectrum of glycogen storage disease in Iranian population using targeted gene sequencing
Clinical and genetic spectrum of glycogen storage disease in Iranian population using targeted gene sequencing Open
View article: Pediatric solid organ transplantation in the era of COVID-19: A follow-up study
Pediatric solid organ transplantation in the era of COVID-19: A follow-up study Open
Background : We aimed to evaluate the impact of COVID-19 outbreak on pediatric transplant outcomes and determine whether to continue pediatric transplant activity or not, and how policies intended our center has been effective in preventin…