Mohammad Moad
YOU?
Author Swipe
View article: Propagation of human prostate tissue from induced pluripotent stem cells
Propagation of human prostate tissue from induced pluripotent stem cells Open
Primary culture of human prostate organoids and patient-derived xenografts is inefficient and has limited access to clinical tissues. This hampers their use for translational study to identify new treatments. To overcome this, we establish…
View article: High-throughput propagation of human prostate tissue from induced-pluripotent stem cells
High-throughput propagation of human prostate tissue from induced-pluripotent stem cells Open
Primary culture of human prostate organoids is slow, inefficient and laborious. To overcome this, we demonstrate a new high-throughput model where rapidly proliferating and easily handled induced pluripotent stem cells, for the first time,…
View article: Correction: The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance
Correction: The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance Open
The original version of this article contained an error in Fig. 5a where the colours of the labels representing the Hinge and LBD of the AR were incorrect and did not match the corresponding exons. The corrected version of this Figure now …
View article: Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis
Differentiation of Human Embryonic Stem Cells to Sympathetic Neurons: A Potential Model for Understanding Neuroblastoma Pathogenesis Open
Background and Aims . Previous studies modelling human neural crest differentiation from stem cells have resulted in a low yield of sympathetic neurons. Our aim was to optimise a method for the differentiation of human embryonic stem cells…
View article: A Unifying Theory of Branching Morphogenesis
A Unifying Theory of Branching Morphogenesis Open
The morphogenesis of branched organs remains a subject of abiding interest. Although much is known about the underlying signaling pathways, it remains unclear how macroscopic features of branched organs, including their size, network topol…
View article: Using induced pluripotent stem cells as a tool for modelling carcinogenesis
Using induced pluripotent stem cells as a tool for modelling carcinogenesis Open
Cancer is a highly heterogeneous group of diseases that despite improved treatments remain prevalent accounting for over 14 million new cases and 8.2 million deaths per year. Studies into the process of carcinogenesis are limited by lack o…