Mohammad Nikpassand
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View article: Preparation, characterization and application of MT@SP@GBP and their use for synthesis of novel pyrazolophthalazine-5,10-diones
Preparation, characterization and application of MT@SP@GBP and their use for synthesis of novel pyrazolophthalazine-5,10-diones Open
View article: Enhanced therapeutic efficacy of silibinin loaded silica coated magnetic nanocomposites against Pseudomonas aeruginosa in Combination with Ciprofloxacin and HepG2 cancer cells
Enhanced therapeutic efficacy of silibinin loaded silica coated magnetic nanocomposites against Pseudomonas aeruginosa in Combination with Ciprofloxacin and HepG2 cancer cells Open
Silibinin, a major bioactive compound extracted from Silybum marianum, possesses notable antioxidant, antitumor, hepatoprotective, and antibacterial activities. However, its poor solubility limits its clinical applications. This study aime…
View article: Potential energy surfaces and dynamic study of 4,6-diphenylpyrimidin-2(1H)-one from multicomponent reaction of benzaldehyde, acetophenone and urea
Potential energy surfaces and dynamic study of 4,6-diphenylpyrimidin-2(1H)-one from multicomponent reaction of benzaldehyde, acetophenone and urea Open
View article: Synthesis of new organic-inorganic hybride of Kit-6-NH2@Vanillin@α-methyleneacetophenone@ acridine-Cu(ꟾ) as a recoverable Lewis acid catalyst and its application for the synthesis of azoacridines
Synthesis of new organic-inorganic hybride of Kit-6-NH2@Vanillin@α-methyleneacetophenone@ acridine-Cu(ꟾ) as a recoverable Lewis acid catalyst and its application for the synthesis of azoacridines Open
Kit-6-NH2@Vanillin@ α-methyleneacetophenone @ acridine-Cu (ꟾ) nanoparticles were synthesized and were characterized completely. Then, the application of this new nano catalyst for the preparation of azo-derived dihydropyridines (acridines)…
View article: Silibinin‐Loaded Nanoparticles for Drug Delivery in Gastric Cancer: In Vitro Modulating <scp>miR</scp>‐181a and <scp>miR</scp>‐34a to Inhibit Cancer Cell Growth and Migration
Silibinin‐Loaded Nanoparticles for Drug Delivery in Gastric Cancer: In Vitro Modulating <span>miR</span>‐181a and <span>miR</span>‐34a to Inhibit Cancer Cell Growth and Migration Open
Silibinin (C 25 H 22 O 10 ), a notable bioactive flavonolignans, is recognized for its anticancer properties. However, due to its poor water solubility, the objective of this study was to design and synthesize nanocarriers to enhance the s…
View article: Enhancing the Therapeutic Efficacy of silibinin via Silica-Coated magnetic Nanocomposite against Pseudomonas aeruginosa isolates and HepG2 cancer cells Running title: Potential therapeutic properties of silibinin
Enhancing the Therapeutic Efficacy of silibinin via Silica-Coated magnetic Nanocomposite against Pseudomonas aeruginosa isolates and HepG2 cancer cells Running title: Potential therapeutic properties of silibinin Open
Introduction: Silibinin is a notable component extracted from Silybum marianum with antioxidant, antitumor, hepatoprotective, and antibacterial activities. This study aims to enhance the delivery of silibinin by synthesizing magnetic nanoc…
View article: Synthesis of novel 4-arylidene-benzodiazepines using Cellulose@SiPr@Catechin@Fe3O4
Synthesis of novel 4-arylidene-benzodiazepines using Cellulose@SiPr@Catechin@Fe3O4 Open
This research work describes the synthesis and characterization of Cellulose@SiPr@Catechin@Fe3O4 nanocomposite, a novel and effective nanocatalyst in the synthesis of 1,5-benzodiazepine derivatives by reaction of 1,2-phenylenediamine, Meld…
View article: Finding the Best Proposed Mechanism for Ugi Multi-Component Reaction by DFT Study
Finding the Best Proposed Mechanism for Ugi Multi-Component Reaction by DFT Study Open
The one-pot four-component condensation of benzoic acid (R1), aniline (R2), benzaldehyde (R3), and 2-isocyano-2-methylpropane was investigated at the B3LYP/6-311G** level to explore the reaction mechanism as a theoretical study. All routes…
View article: “Glucono-delta-lactone” as a substrate for preparation of new magnetically recoverable nanocatalyst for the environmentally benign synthesis of novel azo linked 3-methyl-isoxazol-5-ones
“Glucono-delta-lactone” as a substrate for preparation of new magnetically recoverable nanocatalyst for the environmentally benign synthesis of novel azo linked 3-methyl-isoxazol-5-ones Open
Silica-coated Fe3O4 nanoparticles bound to Glucono-delta-lactone (GDL) magnetic nanoparticles (Fe3O4@SiPr@GDL MNPs) were prepared and characterized by TEM, EDX, TGA/DTG, Zeta Potential, BET, FE-S…
View article: Sustainable conversion of carbon dioxide into novel 5-aryldiazenyl-1,2,4-triazol-3-ones using Fe<sub>3</sub>O<sub>4</sub>@SP-vanillin-TGA nanocomposite
Sustainable conversion of carbon dioxide into novel 5-aryldiazenyl-1,2,4-triazol-3-ones using Fe<sub>3</sub>O<sub>4</sub>@SP-vanillin-TGA nanocomposite Open
A series of novel 5-aryldiazenyl-1,2,4-triazol-3-ones are synthesized at room temperature in short reaction time, and excellent yields via four-component reaction between 4-aryldiazenyl-salicylaldehydes, ammonium acetate, arylhydrazine, an…
View article: Green Synthesis of Aryl Naphthoxazine-2-thiones Using NiFe<sub>2</sub>O<sub>4</sub>@SiO<sub>2</sub><i><sup>n</sup></i>Pr@GA Under Ultrasound Irradiation
Green Synthesis of Aryl Naphthoxazine-2-thiones Using NiFe<sub>2</sub>O<sub>4</sub>@SiO<sub>2</sub><i><sup>n</sup></i>Pr@GA Under Ultrasound Irradiation Open
Green Synthesis of Aryl Naphthoxazine-2-thiones Using NiFe2O4@SiO2nPr@GA Under Ultrasound Irradiation
View article: Sustainable Synthesis of New Azo-Linked 1,5-Diaryl-1,2,4-Triazolones from Carbon Dioxide Using Fe3o4@Sp@Vanillin@Tga Nanocomposite
Sustainable Synthesis of New Azo-Linked 1,5-Diaryl-1,2,4-Triazolones from Carbon Dioxide Using Fe3o4@Sp@Vanillin@Tga Nanocomposite Open
View article: Green synthesis of novel 5-amino-bispyrazole-4-carbonitriles using a recyclable Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@vanillin@thioglycolic acid nano-catalyst
Green synthesis of novel 5-amino-bispyrazole-4-carbonitriles using a recyclable Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub>@vanillin@thioglycolic acid nano-catalyst Open
Bis(thioglycolic acid)-vanillin silica-coated Fe 3 O 4 MNPs were synthesized, and tested as a catalyst.
View article: Evaluation of [<sup>99m</sup>Tc][Tc-HYNIC/EDDA]-Tyr as a target for metabolic tumor imaging in B16F10 melanoma tumor.
Evaluation of [<sup>99m</sup>Tc][Tc-HYNIC/EDDA]-Tyr as a target for metabolic tumor imaging in B16F10 melanoma tumor. Open
These data suggest that the novel radiotracer ([99mTc][Tc-HYNIC/EDDA]-Tyr) as an protein metabolism imaging agent, is able to transfer into melanoma cells and show great expectation for the clinical application in the imaging of…
View article: Synthesis of Novel Azo-Linked 5-Amino-Pyrazole-4-Carbonitrile Derivatives Using Tannic Acid–Functionalized Silica-Coated Fe3O4 Nanoparticles as a Novel, Green, and Magnetically Separable Catalyst
Synthesis of Novel Azo-Linked 5-Amino-Pyrazole-4-Carbonitrile Derivatives Using Tannic Acid–Functionalized Silica-Coated Fe3O4 Nanoparticles as a Novel, Green, and Magnetically Separable Catalyst Open
Tannic acid–linked silica-coated Fe 3 O 4 nanoparticles (Fe 3 O 4 @SiO 2 @Tannic acid) were prepared and characterized by transmission electron microscope (TEM), field emission scanning electron microscope (FE-SEM), X-ray powder diffractio…
View article: One-pot Synthesis of New Category of 2-aryl-quinazolinones Using of DSDABCO as an Efficient Heterocyclic Medium
One-pot Synthesis of New Category of 2-aryl-quinazolinones Using of DSDABCO as an Efficient Heterocyclic Medium Open
A series of 2-aryl-quinazolin-4(1H)-ones have been synthesized in short reaction times and excellent yields through one-pot reaction between isatoic anhydride, glycine and various aldehydes in the presence of DSDABCO (1,4-disulfo-1,4-diazo…
View article: Tetramethylguanidine-functionalized melamine as a multifunctional organocatalyst for the expeditious synthesis of 1,2,4-triazoloquinazolinones
Tetramethylguanidine-functionalized melamine as a multifunctional organocatalyst for the expeditious synthesis of 1,2,4-triazoloquinazolinones Open
View article: DFT Study of Aromatization on Azo-Linked Cyclopentadienides
DFT Study of Aromatization on Azo-Linked Cyclopentadienides Open
he aromatic behavior of the azo-linked cyclopentadienide derivatives have been revealed in various natural compounds. In Tthis research, density functional theory (DFT) calculations at the B3LYP level are used to optimize the geometry of t…
View article: Green synthesis of 4,6-bisarylpyrimidin-2(1H)-ones and azo-linked 4-arylpyrimidin-2(1H)-ones using NiFe2O4@SiO2Pr@glucose amine as a mild nano catalyst
Green synthesis of 4,6-bisarylpyrimidin-2(1H)-ones and azo-linked 4-arylpyrimidin-2(1H)-ones using NiFe2O4@SiO2Pr@glucose amine as a mild nano catalyst Open
The clean, environmentally benign and effective synthesis of novel azo-linked 4-arylpyrimidin-2(1H)-one derivatives and 4,6-bisarylpyrimidin-2(1H)-ones via three-component reaction of various aldehydes or synthetized azo-linked aldehydes, …
View article: Catalyst-free Synthesis of Mono and Bis Spiro Pyrazolopyridines in DSDABCO as a Novel Media
Catalyst-free Synthesis of Mono and Bis Spiro Pyrazolopyridines in DSDABCO as a Novel Media Open
In this work, multicomponent synthesis of mono and bis spiro-pyrazolopyridines from isatin derivatives, indanedione and 3-methyl-5-aminopyrazole at the presence of 1,4-disulfo-1,4-diazoniabicyclo[2.2.2]octane chloride (DSDABCO) as a novel …
View article: DFT study of azo linkage effect on homoaromatization of some 1,4-dihydropryridines
DFT study of azo linkage effect on homoaromatization of some 1,4-dihydropryridines Open
1,4-dihydropryridine derivatives revealed various biological activities and pharmacological properties such as antiviral, antibacterial and anti-inflammatory activities. In this research, density functional theory (DFT) calculations at the…
View article: Solvent-free Synthesis and DFT Studies on Mechanistic Pathway of 4-Aryl-4,10-Dihydroindeno[1,2-<i>b</i>]Pyrazolo[4,3-<i>e</i>]Pyridin-5(<i>1H</i>)-ones
Solvent-free Synthesis and DFT Studies on Mechanistic Pathway of 4-Aryl-4,10-Dihydroindeno[1,2-<i>b</i>]Pyrazolo[4,3-<i>e</i>]Pyridin-5(<i>1H</i>)-ones Open
A novel, efficient, and grind stone procedure for the synthesis of pyrazolo[4,3-e]pyridine compounds at room temperature was reported. This methodology offers several advantages such as mild conditions, excellent yields, simple proc…
View article: NiFe <sub>2</sub>O <sub>4</sub>@Sio <sub>2</sub> <sup><i>n</i></sup>Pr@Glucose Amine Nanoparticles as a Green and Magnetically Separable Catalyst for the Grinding Synthesis of Aryl Naphtho[1,3]Oxazine-2-Thiones
NiFe <sub>2</sub>O <sub>4</sub>@Sio <sub>2</sub> <sup><i>n</i></sup>Pr@Glucose Amine Nanoparticles as a Green and Magnetically Separable Catalyst for the Grinding Synthesis of Aryl Naphtho[1,3]Oxazine-2-Thiones Open
View article: Correction to: Control releasing 5-aminosalicylic acid using pH-sensitive hydrogel with novel albumin cross-linker
Correction to: Control releasing 5-aminosalicylic acid using pH-sensitive hydrogel with novel albumin cross-linker Open
View article: Synthesis of bis coumarinyl methanes using of potassium 2-oxoimidazolidine-1,3-diide as a novel, efficient and reusable catalyst
Synthesis of bis coumarinyl methanes using of potassium 2-oxoimidazolidine-1,3-diide as a novel, efficient and reusable catalyst Open
At first, potassium 2-oxoimidazolidine-1,3-diide (POImD) was prepared of stirring a mixture of imidazolidin-2-one, KOH and H2O overnight. Then, Potassium 2-oxoimidazolidine-1,3-diide was used as a green, novel, fast, efficient and mild cat…
View article: Recent advances in the application of nano-catalysts for Hiyama cross-coupling reactions
Recent advances in the application of nano-catalysts for Hiyama cross-coupling reactions Open
This mini-review highlights the recent developments in the field of metal nanoparticle (NP) catalyzed Hiyama cross-coupling reactions.
View article: POTASSIUM 2-OXOIMIDAZOLIDINE-1,3-DIIDE AS A NOVEL CATALYST FOR GRIND SYNTHESIS OF PYRANO[4,3- b ]CHROMENONE
POTASSIUM 2-OXOIMIDAZOLIDINE-1,3-DIIDE AS A NOVEL CATALYST FOR GRIND SYNTHESIS OF PYRANO[4,3- b ]CHROMENONE Open
A novel, clean, mild and eco-friendly benign route to pyrano[4,3 -b ]chromenes through cyclocondensation reaction of β -naphthol, aldehydes and 4-hydroxycoumarin, using POImD as a novel and reusable organometallic catalyst, is described. …
View article: Potassium 2-oxoimidazolidine-1,3-diide: An effective and new catalyst for the grinding synthesis of (1H-indol-3-yl)methyl-2H-indan-1,3-diones
Potassium 2-oxoimidazolidine-1,3-diide: An effective and new catalyst for the grinding synthesis of (1H-indol-3-yl)methyl-2H-indan-1,3-diones Open
Potassium 2-oxoimidazolidine-1,3-diide (POImD) is easily used as an efficient and recyclable catalyst for the synthesis of 2H-indene-1,3-dione derivatives by a reaction between indoles, 2H-indene-1,3-dione and aldehydes at room temperature…
View article: Ultrasonochemical synthesis of 2,3-dihydrofuranediones in aqueous medium
Ultrasonochemical synthesis of 2,3-dihydrofuranediones in aqueous medium Open
2,3-Dihydrofuranediones were prepared by an efficient one-pot multicomponent Knoevnagel-like condensation between pyrazolecarbaldehydes or indole-3-carbaldehyde, ethyl pyruvate and bromine, followed by an intramolecular cyclization in aque…
View article: Synthesis and characterization of amino glucose-functionalized silica-coated NiFe<sub>2</sub>O<sub>4</sub> nanoparticles: a heterogeneous, new and magnetically separable catalyst for the solvent-free synthesis of pyrano[3,2-<i>c</i>]chromen-5(4<i>H</i>)-ones
Synthesis and characterization of amino glucose-functionalized silica-coated NiFe<sub>2</sub>O<sub>4</sub> nanoparticles: a heterogeneous, new and magnetically separable catalyst for the solvent-free synthesis of pyrano[3,2-<i>c</i>]chromen-5(4<i>H</i>)-ones Open
We have developed NiFe2O4@SiO2@glucose amine as a new, mild and efficient avenue for the synthesis of pyrano[3,2-c]chromen-5(4H)-ones.