Explanipedia

Lime and Nano-Limestone Composite-Based Pretreatment and Adsorption Strategies for Olive Mill Wastewater Treatment: Toward Efficient and Sustainable Solutions Open

Abeer Al Bawab, Razan Afaneh, Muna Abu‐Dalo, Fadwa Odeh, Mustafa Al Kuisi , et al. · 2025

The treatment of olive mill wastewater (OMW) remains a major environmental challenge due to its high organic load and phenolic content. This study investigates a combined approach using lime pretreatment and limestone (LS)-based adsorption…

Clarithromycin-Loaded Albumin-Based Nanoparticles for Improved Antibacterial and Anticancer Performance Open

Walhan Alshaer, Shrouq Alsotari, Nour Aladaileh, A Rifai, Aya Khalaf , et al. · 2025

Background/Objectives: Clarithromycin (CLA) is a widely used antibiotic effective against a variety of bacterial strains, making it a common treatment for respiratory, skin, and soft tissue infections. Moreover, extensive studies have conf…

Effect of cucurbit[7]uril on DPPC-containing liposomes: Interactions with the lipid bilayer Open

Summay Altaher, Walhan Alshaer, Fedaa Adaileh, Hamdi Nsairat, Shrouq Alsotari , et al. · 2025

Liposomes, which are bilayer lipidic nanocarriers, have been utilized in many pharmaceutical applications to enhance the solubility and therapeutic index of drugs. Liposomes have also been used as carriers for smaller drug carriers, such a…

Sustainable dye remediation using Casuarina equisetifolia fruit-derived activated carbon Open

Alaa M. Al-Ma’abreh, Dareen A. Hmedat, Gada Edris, Fadwa Odeh, Mariam A Hamed · 2025

In this research, Casuarina equisetifolia fruit-based-activated carbon (CAC) was employed to investigate the simultaneous removal of crystal violet (CV), Naphthol Black Blue (NBB), and methyl orange (MO) in one mixture from aqueous solutio…

Removal of phenolic compounds from olive mill wastewater (OMW) by tailoring the surface of activated carbon under acidic and basic conditions Open

Abeer Al Bawab, Muna Abu‐Dalo, Hussein Kanaan, Nathir A. F. Al‐Rawashdeh, Fadwa Odeh · 2025

Olive mill wastewater (OMW), a by-product of olive oil production, poses significant environmental risks due to its acidity and high polyphenol content, particularly in water-scarce regions like Jordan. This study developed a cost-effectiv…

Thymoquinone chemically conjugated to doxorubicin: antitumor activity and subcellular localization Open

Ismail Sami Mahmoud, Hamdi Nsairat, Shorouq Alsotari, Areej M. Jaber, Ezaldeen Esawi , et al. · 2025

A hybrid drug of thymoquinone (TQ)-doxorubicin (Dox) has been generated and characterized for cellular localization and anti-cancer activity in cancer cell lines.

Recent advances in using liposomes for delivery of nucleic acid-based therapeutics Open

Hamdi Nsairat, Walhan Alshaer, Fadwa Odeh, Ezaldeen Esawi, Dima Khater , et al. · 2023

Nucleic acid therapeutics are rapidly expanding because of recent advancements in production and purification. This class of therapeutics may change the field of disease treatment and personalized medicine since it can cure diseases. Howev…

Jordanian Kaolinite with TiO2 for Improving Solar Light Harvesting Used in Dye Removal Open

Manal Alkhabbas, Fadwa Odeh, Khitam Alzughoul, Razan Afaneh, Waed Alahmad · 2023

TiO2-Kaolinite nanocomposite photocatalysts were synthesized using the sol-gel method, with titanium isopropoxide/HCl as reactants and Jordanian kaolinite clay as a support material. The samples’ TiO2 content ranged from 10% to 70% (m/m). …

Liposomes: structure, composition, types, and clinical applications Open

Hamdi Nsairat, Dima Khater, Usamah Sayed, Fadwa Odeh, Abeer Al Bawab , et al. · 2022

Synthesis of Mono-Amino Substituted γ-CD: Host–Guest Complexation and In Vitro Cytotoxicity Investigation Open

Fadwa Odeh, Fedaa Adaileh, Walhan Alshaer, Hamdi Nsairat, Dana A. Alqudah , et al. · 2022

Cyclodextrins (CDs) are cyclic oligosaccharides which can trap hydrophobic molecules and improve their chemical, physical, and biological properties. γ-CD showed the highest aqueous solubility with the largest cavity diameter among other C…

Coupling magnetite and goethite nanoparticles with sorbent materials for olive mill wastewater remediation Open

Fadwa Odeh, Muna Abu‐Dalo, Borhan Albiss, Noor Ghannam, Aya Khalaf , et al. · 2022

This work aimed at treating OMW by developing an environmentally friendly and cost-effective media capable of removing phenolic compounds upon the interaction between magnetic nanoparticles and sorbent material such as zeolite. Magnetite (…

Cinnamaldehyde–cucurbituril complex: investigation of loading efficiency and its role in enhancing cinnamaldehyde in vitro anti-tumor activity Open

Bayan Al Tbakhi, Hamdi Nsairat, Walhan Alshaer, Abdulfattah Al-Kadash, Wissam Helal , et al. · 2022

This study aimed to clarify the physico-chemical properties of cucurbit[7]uril (CB[7]) and cinnamaldehyde (Cinn) inclusion complexes (CB[7]–Cinn) and their resulting antitumor activity.

Preparation, characterization, and biological activity study of thymoquinone-cucurbit[7]uril inclusion complex Open

Lubna Alrawashdeh, Khaleel I. Assaf, Walhan Alshaer, Fadwa Odeh, Suhair A. Bani‐Atta · 2022

The host–guest inclusion complexation of thymoquinone by cucurbit[7]uril in aqueous solution is established, which results in an enhanced biological activity.

Green Synthesis of Silver Nanoparticles as an Effective Antibiofouling Material for Polyvinylidene Fluoride (PVDF) Ultrafiltration Membrane Open

Nour Alnairat, Muna Abu Dalo, Rund Abu‐Zurayk, Saida Abu Mallouh, Fadwa Odeh , et al. · 2021

Silver nanoparticles (AgNPs) were successfully synthesized using the aqueous extract of the Paronychia argentea Lam (P. argentea) wild plant. The results showed that the conversion of Ag+ to Ag0 nanoparticles ratio reached 96.5% as determi…

Lipid nanostructures for targeting brain cancer Open

Hamdi Nsairat, Dima Khater, Fadwa Odeh, Fedaa Adaileh, Suma Al-Taher , et al. · 2021

Advancements in both material science and bionanotechnology are transforming the health care sector. To this end, nanoparticles are increasingly used to improve diagnosis, monitoring, and therapy. Huge research is being carried out to impr…

Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review Open

Dima Khater, Hamdi Nsairat, Fadwa Odeh, Mais M. Saleh, Areej M. Jaber , et al. · 2021

Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles as they not only facilitate penetration across skin but also avoid the drawback…

Impact of Nanoscale Magnetite and Zero Valent Iron on the Batch-Wise Anaerobic Co-Digestion of Food Waste and Waste-Activated Sludge Open

Ghada Kassab, Dima Khater, Fadwa Odeh, Khaldoun Shatanawi, Maha Halalsheh , et al. · 2020

As a potential approach for enhanced energy generation from anaerobic digestion, iron-based conductive nanoparticles have been proposed to enhance the methane production yield and rate. In this study, the impact of two different types of i…

CCDC 1581648: Experimental Crystal Structure Determination Open

Firas F. Awwadi, Deeb Taher, Mohammed H. Kailani, Manal I. Alwahsh, Fadwa Odeh , et al. · 2020

CCDC 1581990: Experimental Crystal Structure Determination Open

Firas F. Awwadi, Deeb Taher, Mohammed H. Kailani, Manal I. Alwahsh, Fadwa Odeh , et al. · 2020

CCDC 1581646: Experimental Crystal Structure Determination Open

Firas F. Awwadi, Deeb Taher, Mohammed H. Kailani, Manal I. Alwahsh, Fadwa Odeh , et al. · 2020

CCDC 1581647: Experimental Crystal Structure Determination Open

Firas F. Awwadi, Deeb Taher, Mohammed H. Kailani, Manal I. Alwahsh, Fadwa Odeh , et al. · 2020

Grafting of anti-nucleolin aptamer into preformed and remotely loaded liposomes through aptamer-cholesterol post-insertion Open

Hamdi Nsairat, Ismail Sami Mahmoud, Fadwa Odeh, Duaa Abuarqoub, Hafsa Al-Azzawi , et al. · 2020

A new combination strategy of an active loading and active targeting approach was applied in this work.

Aptamers Chemistry: Chemical Modifications and Conjugation Strategies Open

Fadwa Odeh, Hamdi Nsairat, Walhan Alshaer, Mohammad A. Ismail, Ezaldeen Esawi , et al. · 2019

Soon after they were first described in 1990, aptamers were largely recognized as a new class of biological ligands that can rival antibodies in various analytical, diagnostic, and therapeutic applications. Aptamers are short single-strand…

Co-encapsulation of thymoquinone with docetaxel enhances the encapsulation efficiency into PEGylated liposomes and the chemosensitivity of MCF7 breast cancer cells to docetaxel Open

Fadwa Odeh, Randa Naffa, Hanan Azzam, Ismail Sami Mahmoud, Walhan Alshaer , et al. · 2019

Combinatorial therapeutic strategies to eradicate tumors can be superior to a single therapeutic modality. Docetaxel (DT) has been approved for the treatment of local or metastasized breast cancer alone or in combination with other chemoth…

Remote loading of curcumin-in-modified β-cyclodextrins into liposomes using a transmembrane pH gradient Open

Fadwa Odeh, Hamdi Nsairat, Walhan Alshaer, Shrouq Alsotari, Rula Buqaien , et al. · 2019

The current study provides a novel remote loading approach utilizing chemically modified cyclodextrins to incorporate hydrophobic drugs into liposomes.

Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma Open

Walhan Alshaer, Manar Zraikat, Amer Amer, Hamdi Nsairat, Zainab Lafi , et al. · 2019

Echinomycin, a DNA bis-intercalator peptide antibiotic, was complexed with γCD and loaded into PEGylated liposomes. The liposomes encapsulating echinomycin showed potent anti-proliferative and anti-invasive effect against U-87 MG glioblast…

Correction: Selection and targeting of EpCAM protein by ssDNA aptamer Open

Walhan Alshaer, Nidaa A. Ababneh, Ma’mon M. Hatmal, Heba Izmirli, Moujab Choukeife , et al. · 2018

[This corrects the article DOI: 10.1371/journal.pone.0189558.].

Dynamic NMR Study of Model CMP Slurry Containing Silica Particles as Abrasives Open

Fadwa Odeh, Abeer Al Bawab, Y Li · 2018

Chemical mechanical planarization (CMP) should provide a good surface planarity with minimal surface defectivity. Since CMP slurries are multi-component systems, it is very important to understand the various processes and interactions tak…

Olive mill wastewater treatment in Jordan: A Review Open

Abeer Al Bawab, Noor Ghannam, Saida Abu-Mallouh, Ayat Bozeya, Rund Abu‐Zurayk , et al. · 2018

The environmental impact of olive mill wastewater (OMW) pollution is a public concern. OMW contains high levels of phenols, organic compounds, chemical oxygen demand (COD), biological oxygen demand (BOD), microorganisms, nutrients, and tox…

Selection and targeting of EpCAM protein by ssDNA aptamer Open

Walhan Alshaer, Nidaa A. Ababneh, Ma’mon M. Hatmal, Heba Izmirli, Moujab Choukeife , et al. · 2017

Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small molecules to whole living cells. Sever…

Fadwa Odeh YOU? Author Swipe