Mohammad Sadegh Rezai
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View article: The Efficacy of Inhaled Phage Cocktail to Prevent Ventilator-Associated Pneumonia in Children: A Double-Blind Clinical Trial
The Efficacy of Inhaled Phage Cocktail to Prevent Ventilator-Associated Pneumonia in Children: A Double-Blind Clinical Trial Open
Background/Objectives: Phage therapy is gaining attention as a potential alternative to antibiotics. This study investigates the potential use of a phage cocktail as a preventive measure against ventilator-associated pneumonia (VAP) in chi…
View article: Antimicrobial Resistance in Gram-Negative Bacterial Pneumonia After the COVID-19 Pandemic in Northern Iran
Antimicrobial Resistance in Gram-Negative Bacterial Pneumonia After the COVID-19 Pandemic in Northern Iran Open
Background: The irrational use of antibiotics has become a significant factor in the escalating global crisis of antimicrobial resistance (AMR). AMR is linked to an increasing burden of healthcare-associated infections caused by multidrug-…
View article: Achievements of the PERSIAN Birth Cohorts: A Systematic Review
Achievements of the PERSIAN Birth Cohorts: A Systematic Review Open
Background: Birth cohort studies are a subset of cohort studies in which a group of individuals is followed over time. Information about the number of published articles derived from these studies, as well as their research areas, is cruci…
View article: High prevalence of antimicrobial resistance genes in multidrug-resistant-ESBLs-producing Klebsiella pneumoniae post-COVID-19 pandemic
High prevalence of antimicrobial resistance genes in multidrug-resistant-ESBLs-producing Klebsiella pneumoniae post-COVID-19 pandemic Open
Background and Objectives: Klebsiella pneumoniae is a common pathogen associated with healthcare-related infections. It is particularly notable for its ability to develop resistance to multiple antibiotics, making treatment challenging. Du…
View article: Updating the Antimicrobial Resistance Pattern among Critical Priority Pathogens in the Intensive Care Unit in Northern Iran Post COVID-19 Pandemic
Updating the Antimicrobial Resistance Pattern among Critical Priority Pathogens in the Intensive Care Unit in Northern Iran Post COVID-19 Pandemic Open
Background: During the COVID-19 pandemic, the widespread and indiscriminate prescription of antibiotics led to a significant increase in antibiotic resistance and the emergence of multi-drug-resistant (MDR) strains. This study aims to eval…
View article: Clinical Characteristics of COVID-19 in Neonates and Infants Younger Than 3 Months
Clinical Characteristics of COVID-19 in Neonates and Infants Younger Than 3 Months Open
Background: COVID-19 is a respiratory infection that was generated in 2019 as a pandemic affecting children and adults. Objectives: To better understand COVID-19 in young children, we evaluated the epidemiological, clinical, and outcomes o…
View article: Correction: Clinical characteristics and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 infection in Iran: A multicenter study
Correction: Clinical characteristics and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 infection in Iran: A multicenter study Open
[This corrects the article DOI: 10.1371/journal.pone.0274104.].
View article: The Effect of Watching Cartoon on Pain and Anxiety of Venipuncture in 3-6 Year-Old Children: A Randomized Controlled Clinical Trial
The Effect of Watching Cartoon on Pain and Anxiety of Venipuncture in 3-6 Year-Old Children: A Randomized Controlled Clinical Trial Open
Background: Injection-induced anxiety in children is a significant issue, as the pain from injections creates both physical and psychological stress, reducing the child's tolerance and cooperation. Objectives: To determine the effect of wa…
View article: Clinical characteristics of COVID-19 in children: a large multicenter study from Iran
Clinical characteristics of COVID-19 in children: a large multicenter study from Iran Open
Introduction During the COVID-19 pandemic, pediatric cases typically exhibit milder symptoms and lower mortality rates. However, the delay in pediatric vaccination poses major risks for children. This multicenter study aimed to comprehensi…
View article: The Emergence of Multi-drug-resistant and Extensively-drug-resistant Pseudomonas aeruginosa After the COVID‑19 Pandemic in North Iran
The Emergence of Multi-drug-resistant and Extensively-drug-resistant Pseudomonas aeruginosa After the COVID‑19 Pandemic in North Iran Open
View article: Evaluation of antibiotic resistance changes in Acinetobacter baumannii in the era of COVID-19 in Northern Iran
Evaluation of antibiotic resistance changes in Acinetobacter baumannii in the era of COVID-19 in Northern Iran Open
Background and Objectives: During the coronavirus pandemic, the overuse of antibiotics to reduce coinfections and mor- tality may be contributing to the rise of antimicrobial resistance. In this study, we aim to investigate the antibiotic …
View article: Unusual presentation of miliary tuberculosis in a 12-year-old girl: a case report
Unusual presentation of miliary tuberculosis in a 12-year-old girl: a case report Open
View article: Tuberculosis Meningitis in a 9‐Month‐Old Girl during the COVID‐19 Pandemic
Tuberculosis Meningitis in a 9‐Month‐Old Girl during the COVID‐19 Pandemic Open
Tuberculous meningitis (TBM) is a serious form of TB disease that can result in high morbidity and mortality, particularly if there are delays in diagnosis and treatment. In this case report, a 9‐month‐old girl was admitted with persistent…
View article: High Prevalence of Antimicrobial Resistance Genes in Multidrug-Resistant Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> Clinical Isolates after COVID-19 Pandemic, North Iran.
High Prevalence of Antimicrobial Resistance Genes in Multidrug-Resistant Extended-Spectrum Beta-Lactamase-Producing <i>Escherichia coli</i> Clinical Isolates after COVID-19 Pandemic, North Iran. Open
In the current study, over 50% of MDR-ESBL-producing Escherichia coli isolates exhibited resistance to antibiotics. A combination of antibiotics, including piperacillin-tazobactam and colistin, is recommended for treating extensivel…
View article: Outcome of Children with SARS-CoV-2 Related Multisystem Inflammatory Syndrome (MIS-C) Treated with Corticosteroids: A Systematic Review and Meta-Analysis
Outcome of Children with SARS-CoV-2 Related Multisystem Inflammatory Syndrome (MIS-C) Treated with Corticosteroids: A Systematic Review and Meta-Analysis Open
View article: Macrolide-resistant Mycoplasma pneumoniae in an Iranian Pediatric Sample with Community-Acquired Pneumonia
Macrolide-resistant Mycoplasma pneumoniae in an Iranian Pediatric Sample with Community-Acquired Pneumonia Open
Background: To the best of our knowledge, the prevalence of macrolide-resistant Mycoplasma pneumoniae (MRM) in Iranian children has not been investigated. Objectives: The present study aimed to evaluate the prevalence of MRM in Iranian chi…
View article: Multisystem Inflammatory Syndrome Mortality Following COVID-19 in Iranian Children: A Case Series and Literature Review
Multisystem Inflammatory Syndrome Mortality Following COVID-19 in Iranian Children: A Case Series and Literature Review Open
Background: Children generally are less contaminated by COVID-19 than other age groups, but multisystem inflammatory syndrome-children (MIS-C) can cause severe outcomes in some children. The information about MIS-C patient mortality is lim…
View article: Inhalation phage therapy as a new approach to preventing secondary bacterial pneumonia in patients with moderate to severe COVID-19: A double-blind clinical trial study
Inhalation phage therapy as a new approach to preventing secondary bacterial pneumonia in patients with moderate to severe COVID-19: A double-blind clinical trial study Open
View article: Epidemiological data of national Kawasaki disease registry in Iran, 2007–2019
Epidemiological data of national Kawasaki disease registry in Iran, 2007–2019 Open
Introduction Kawasaki disease(KD) is a vasculitis of childhood that tends to influence the coronary arteries. There is no national data about the prevalence of KD in Iran. This study aimed to perform a national registry in Iran for 13 year…
View article: Multiple Candida strains causing oral infection in COVID-19 patients under corticosteroids and antibiotic therapy: An observational study
Multiple Candida strains causing oral infection in COVID-19 patients under corticosteroids and antibiotic therapy: An observational study Open
Introduction The occurrence of oral candidiasis (OC) is expected in patients with COVID-19, especially those with moderate to severe forms of infection who are hospitalized and may be on long-term use of broad-spectrum antibiotics or prolo…
View article: Rabies Virus Infection: A Case Series and Literature Review
Rabies Virus Infection: A Case Series and Literature Review Open
Background: Rabies is a fatal and often neglected disease leading to encephalomyelitis following a bite by an infected mammal. According to the necessity of rabies disease in Iran, we present four cases of rabies virus infection. Case Pres…
View article: Clinical characteristics and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 infection in Iran: A multicenter study
Clinical characteristics and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 infection in Iran: A multicenter study Open
Objectives This study aimed to assess the clinical characteristics, treatment and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 in five different geographical regions of Iran. Methods In this mult…
View article: P156 Oral Candidiasis among inpatients with COVID-19 in the North of Iran
P156 Oral Candidiasis among inpatients with COVID-19 in the North of Iran Open
Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM Objectives We aimed to characterize oral candidiasis epidemiology, species distribution, and antifungal susceptibility profiles among COVID-19 patients. Methods This observational cr…
View article: Non-effectiveness of Ivermectin on Inpatients and Outpatients With COVID-19; Results of Two Randomized, Double-Blinded, Placebo-Controlled Clinical Trials
Non-effectiveness of Ivermectin on Inpatients and Outpatients With COVID-19; Results of Two Randomized, Double-Blinded, Placebo-Controlled Clinical Trials Open
Background Ivermectin which was widely considered as a potential treatment for COVID-19, showed uncertain clinical benefit in many clinical trials. Performing large-scale clinical trials to evaluate the effectiveness of this drug in the mi…
View article: COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant
COVID-19 in Coincidence with Transient Distal Renal Tubular Acidosis in an Infant Open
Background. Post-COVID-19 nephropathies have been reported profusely in the literature with diverse pathophysiological mechanisms. To the best of our knowledge, this is the first report of transient distal (type 1) renal tubular acidosis (…
View article: Developing a National Minimum Data Set for Kawasaki Disease Registry in Iran
Developing a National Minimum Data Set for Kawasaki Disease Registry in Iran Open
Background Kawasaki Disease is an acute and self-limited systemic inflammatory and febrile illness, which is the most common cause of acquired heart disease in children in developed countries. The incidence of KD in Asian countries is high…
View article: Potential of lytic bacteriophages as disinfectant to control of Pseudomonas aeruginosa on fomites
Potential of lytic bacteriophages as disinfectant to control of Pseudomonas aeruginosa on fomites Open
View article: Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort
Seroepidemiology of HBV, HCV, HIV, HTLV, and CMV in Pregnant Women Referring to Sari Birth Cohort Open
Background: Congenital infections are among the most important conditions threatening human fetal health, the majority of which are caused by viral agents. Screening pregnant women for viral infections is essential because such infections …
View article: Using Probiotics in Infants with Cow’s Milk Allergy: A Randomized Clinical Trial
Using Probiotics in Infants with Cow’s Milk Allergy: A Randomized Clinical Trial Open
Background: One of the most common food allergies in infants is cow’s milk allergy (CMA). There is no available effective therapeutic strategy for this issue. It's important to develop effective approaches to reduce the risk of cow’s milk …
View article: A multicenter retrospective study of clinical features, laboratory characteristics, and outcomes of 166 hospitalized children with coronavirus disease 2019 (COVID‐19): A preliminary report from Iranian Network for Research in Viral Diseases (INRVD)
A multicenter retrospective study of clinical features, laboratory characteristics, and outcomes of 166 hospitalized children with coronavirus disease 2019 (COVID‐19): A preliminary report from Iranian Network for Research in Viral Diseases (INRVD) Open
Background The objectives of this study were to analyze the clinical features and laboratory profiles and risk factors associated with critical illness of children with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Methods …