Mohammad Reza Afarinesh
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View article: Protective effects of omega-3 against procarbazine-induced brain damage in the cerebellum and CA1 Hippocampus of male rats: a focus on oxidative stress mechanisms
Protective effects of omega-3 against procarbazine-induced brain damage in the cerebellum and CA1 Hippocampus of male rats: a focus on oxidative stress mechanisms Open
View article: Possible effects of royal jelly against neuronal injury in the hippocampus of ovariectomized rats with pentylenetetrazol-induced seizures: Role of luteinizing and follicle-stimulating hormones.
Possible effects of royal jelly against neuronal injury in the hippocampus of ovariectomized rats with pentylenetetrazol-induced seizures: Role of luteinizing and follicle-stimulating hormones. Open
RJ may protect against estrogen deficiency and seizure-related adverse effects on hippocampal neurons in OVX rats, highlighting its potential as a beneficial dietary supplement.
View article: Studying the Effect of 12 Weeks of Resistance Training with Sumac Supplementation on Inflammatory and Apoptotic Indices in Male Alzheimer's Mice
Studying the Effect of 12 Weeks of Resistance Training with Sumac Supplementation on Inflammatory and Apoptotic Indices in Male Alzheimer's Mice Open
Introduction: Alzheimer's disease represents the most prevalent form of dementia, characterized by a gradual decline in memory function. This study aimed to examine the impact of 12 weeks of resistance training combined with sumac suppleme…
View article: Dual Effects of Aspirin on Spatial Learning and Memory of Male Rats Following Induction of Permanent Cerebral Ischemia
Dual Effects of Aspirin on Spatial Learning and Memory of Male Rats Following Induction of Permanent Cerebral Ischemia Open
Background: Ischemic stroke can lead to cognitive impairment, and nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to slow down the progression of Alzheimer›s disease (AD). This study focused on rodent models to investigate th…
View article: The Effect of Valproic Acid Administration on Learning, Social Interaction, and Depression Induced by Withdrawal Syndrome in Morphine-dependent Mice
The Effect of Valproic Acid Administration on Learning, Social Interaction, and Depression Induced by Withdrawal Syndrome in Morphine-dependent Mice Open
Background: Opioids can lead to mood disorders, anxiety, depression, and cognitive impairment. Valproic acid (VPA) has neuroprotective effects that can prevent neural degeneration. This study aims to examine the impact of VPA on learning, …
View article: The Effects of Urtica Dioica Root and Rosa Damascena Mill Petal Extracts on Andropause symptoms and Reproductive Characteristics of Middle-age Male Rats
The Effects of Urtica Dioica Root and Rosa Damascena Mill Petal Extracts on Andropause symptoms and Reproductive Characteristics of Middle-age Male Rats Open
Background Andropause starts in middle-aged men and affects hormonal balance and behavioral/sexual functions. The aim of the present study was to determine the effects of two Rosa Damascena Mill. ( Rosaceae, Rosa ) and Urtica dioica L. ( U…
View article: Amelioration of behavioral and histological impairments in somatosensory cortex injury rats by limbal mesenchymal stem cell transplantation
Amelioration of behavioral and histological impairments in somatosensory cortex injury rats by limbal mesenchymal stem cell transplantation Open
Introduction Cortical lesions can cause major sensory and motor impairments, representing a significant challenge in neuroscience and clinical medicine. Limbal mesenchymal stem cells (LMSCs), renowned for their remarkable ability to prolif…
View article: Left Barrel Cortical Neurons Activity following Transplantation of Stem Cells into Right Lesioned-Barrel Cortex in Rats.
Left Barrel Cortical Neurons Activity following Transplantation of Stem Cells into Right Lesioned-Barrel Cortex in Rats. Open
Transplantation of dental pulp mesenchymal SCs significantly improved the neural responses of the left barrel cortex that was depressed in the vehicle group.
View article: Ten days of tapering can improve swimming records and metabolic but not hematological profile in young recreational swimmers
Ten days of tapering can improve swimming records and metabolic but not hematological profile in young recreational swimmers Open
View article: Comparative effects of the alcoholic extract of Terminalia chebula and crocin on stress‑induced anxiety‑like behavior and memory impairment in male rats
Comparative effects of the alcoholic extract of Terminalia chebula and crocin on stress‑induced anxiety‑like behavior and memory impairment in male rats Open
Crocin and Terminalia chebula (T. chebula) were proven to have neuroprotective effects. In this study, we evaluated the preventive effects of crocin and alcoholic extract of the T. chebula alone and in combination to examine their efficacy…
View article: Ten Days of Tapering Can Improve Swimming Records and Metabolic but Not Hematological Profile in Young Recreational Swimmers
Ten Days of Tapering Can Improve Swimming Records and Metabolic but Not Hematological Profile in Young Recreational Swimmers Open
Aim: To investigate the effects of a 10-day tapering on the metabolic and hematologic changes and a 200 m crawl swimming record. Methods: Eighteen male recreational swimmers (11-17 years) underwent an eight-week vigorous-intensity enduranc…
View article: The Investigation of Valproic Acid Administration on Learning, Social Interaction, and Depression Induced by Withdrawal Syndrome in Morphine-Depended Mice
The Investigation of Valproic Acid Administration on Learning, Social Interaction, and Depression Induced by Withdrawal Syndrome in Morphine-Depended Mice Open
Opioid addiction causes mood disorders and increases anxiety, depression, and cognitive impairment. Valproate exerts a neuroprotective effect preventing damage and neural degeneration in epilepsy. The animals were randomly divided into fou…
View article: Alteration in social interaction and tactile discrimination of juvenile autistic‐like rats following tactile stimulation and whisker deprivation
Alteration in social interaction and tactile discrimination of juvenile autistic‐like rats following tactile stimulation and whisker deprivation Open
Introduction Autism spectrum disorder is a developmental disorder that can affect sensory‐motor behaviors in the valproic acid (Val) rodent model of autism. Although whisker deprivation (WD) induces plastic changes in the cortical neurons,…
View article: Temporal order judgment of multisensory stimuli in rat and human
Temporal order judgment of multisensory stimuli in rat and human Open
We do not fully understand the resolution at which temporal information is processed by different species. Here we employed a temporal order judgment (TOJ) task in rats and humans to test the temporal precision with which these species can…
View article: The potential impact of Covid-19 on CNS and psychiatric sequels
The potential impact of Covid-19 on CNS and psychiatric sequels Open
View article: Chronically Pre-treatment of Pistachio Alters the Morphology of CA1 Hippocampus Neurons Following Transient Focal Cerebral Ischemia in Male Wistar Rats.
Chronically Pre-treatment of Pistachio Alters the Morphology of CA1 Hippocampus Neurons Following Transient Focal Cerebral Ischemia in Male Wistar Rats. Open
Pistachio consumption reduces the volume of infarction and neuronal damage and improves neurological disorders after ischemia. Therefore, pretreatment with pistachio would have a protective effect against stroke.
View article: Alteration in Social Interaction and Tactile Discrimination of Juvenile Autistic-Like Rats Following Tactile Stimulation and Whisker Deprivation
Alteration in Social Interaction and Tactile Discrimination of Juvenile Autistic-Like Rats Following Tactile Stimulation and Whisker Deprivation Open
View article: Effect of Administration of Lidocaine at Body Temperature on Anesthesia Success in Rodent Model: A Behavioral and Electrophysiology Study
Effect of Administration of Lidocaine at Body Temperature on Anesthesia Success in Rodent Model: A Behavioral and Electrophysiology Study Open
Introduction: Success in anesthesia administration relieves the perception of pain during surgery. Lidocaine is the most commonly used local anesthetic agent in clinical medicine. Moreover, anesthetic agents’ temperature changes can influe…
View article: P.125 Discriminating sharp-wave ripples and interictal epileptiform discharges in patients with mesial temporal epilepsy using intracranial EEG recordings
P.125 Discriminating sharp-wave ripples and interictal epileptiform discharges in patients with mesial temporal epilepsy using intracranial EEG recordings Open
Background: Interictal epileptiform discharges (IEDs) are known as epilepsy biomarkers for seizure detection, and It is essential for clinicians to detect them from from physiological events with similar temporal frequency characteristics.…
View article: Genetic and epigenetic modifications of F1 offspring’s sperm cells following in utero and lactational combined exposure to nicotine and ethanol
Genetic and epigenetic modifications of F1 offspring’s sperm cells following in utero and lactational combined exposure to nicotine and ethanol Open
View article: The Modulatory Effects of Salbutamol in the Basolateral Nucleus of the Amygdala on Learning and Memory Impairments Induced by Foot-shock Stress in the Male Rat
The Modulatory Effects of Salbutamol in the Basolateral Nucleus of the Amygdala on Learning and Memory Impairments Induced by Foot-shock Stress in the Male Rat Open
The Modulatory Effects of Salbutamol in the Basolateral Nucleus of the Amygdala on Learning and Memory Impairments Induced by Foot-shock Stress in the Male Rat
View article: Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection
Pharmacological mechanism of immunomodulatory agents for the treatment of severe cases of COVID-19 infection Open
View article: In Utero and Lactational Exposure of F1 Adult Pups to Ethanol and Nicotine: Alteration of The Reproductive System and Epigenetic Modifying Enzymes of Sperm Cells?
In Utero and Lactational Exposure of F1 Adult Pups to Ethanol and Nicotine: Alteration of The Reproductive System and Epigenetic Modifying Enzymes of Sperm Cells? Open
Co-use of alcohol and nicotine is a common habit which could affect reproductive system. The present study was designed to investigate the effect of in-utero and lactational exposure of offspring to alcohol, nicotine, and combinations on t…
View article: The Efficacy of Teaching English as a Foreign Language to Iranian Students with Autism Spectrum Disorder on Their Social Skills and Willingness to Communicate.
The Efficacy of Teaching English as a Foreign Language to Iranian Students with Autism Spectrum Disorder on Their Social Skills and Willingness to Communicate. Open
Optimum foreign language pedagogy for students with ASD is applied as an effective context enhancing children's capabilities in social skills and willingness to communicate, provoked through a motivational foreign setting modulation in a n…
View article: Evaluation of sleep disorder and its effective factors in patients with an ischemic heart disease in the CCU ward of Kashan Shahid-Beheshti Hospital during 2017-2018
Evaluation of sleep disorder and its effective factors in patients with an ischemic heart disease in the CCU ward of Kashan Shahid-Beheshti Hospital during 2017-2018 Open
Background: Complaints of sleep disorders are common in ischemic heart patients, even after taking sleeping drugs. Evaluation of the causes of sleep disorders and modifying these factors that lead to the progression of patients' treatment …
View article: Mild Permanent Chronic Thyroid Hormones Insufficiency Induces Cognitive Dysfunction in the Adult Male and Female Rats
Mild Permanent Chronic Thyroid Hormones Insufficiency Induces Cognitive Dysfunction in the Adult Male and Female Rats Open
Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in ratsHulol Saleh Alruhaimi, Ahmed K. Allow, Zunariah Buyong, Muhammed Naser, Shaikh Mizanur
View article: The Effects of De-Whiskering and Congenital Hypothyroidism on The Development of Nitrergic Neurons in Rat Primary Somatosensory and Motor Cortices.
The Effects of De-Whiskering and Congenital Hypothyroidism on The Development of Nitrergic Neurons in Rat Primary Somatosensory and Motor Cortices. Open
Our results suggest that both congenital hypothyroidism and whisker deprivation may disturb normal development of the wS1 and wM1 cortical circuits in which nitrergic neurons are involved.
View article: Specific and Non-Specific Thalamocortical Afferents to the Whisker–Related Sensory Cortical Region in Rats with Congenital Hypothyroidism
Specific and Non-Specific Thalamocortical Afferents to the Whisker–Related Sensory Cortical Region in Rats with Congenital Hypothyroidism Open
Background & Aims: Thyroid hormones are of great importance in the development of the central nervous system. Congenital hypothyroidism may affect the reorganization of specific and non-specific thalamocortical afferents to whisker–related…
View article: Changes in serum biochemical factors associated with opium addiction after addiction desertion.
Changes in serum biochemical factors associated with opium addiction after addiction desertion. Open
According to this study not only the longtime use of opium but also opium with drawerin opium dependent people can change their serum biochemical factors. So recognition, treatment, and prevention of this change could be a new step in impr…
View article: Morphometric Plasticity of Nitric Oxide Containing Neurons in the Barrel Cortex of De-whiskered Rats
Morphometric Plasticity of Nitric Oxide Containing Neurons in the Barrel Cortex of De-whiskered Rats Open
Background: The rodent somatosensory barrel cortex is an ideal model to examine the effect of experience-dependent plasticity on developing brain circuitry. Sensory deprivation such as whisker deprivation may affect neuroanatomical aspects…