Mohammad Shahpouri
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View article: Tumor microenvironment responsive TPZ-loaded core-shell polymeric nanoparticles for selective cancer bioreductive therapy
Tumor microenvironment responsive TPZ-loaded core-shell polymeric nanoparticles for selective cancer bioreductive therapy Open
Purpose: Tumor hypoxia is a key barrier to successful delivery and activity of anti-cancer agents. To tackle this, we designed hypoxia-responsive Au-PEI-Azo-mPEG nanoparticles (NPs) denoted as APAP NPs for targeted delivery of hypoxia acti…
View article: Codelivery of methotrexate and silibinin by niosome nanoparticles for enhanced chemotherapy of CT26 colon cancer cells
Codelivery of methotrexate and silibinin by niosome nanoparticles for enhanced chemotherapy of CT26 colon cancer cells Open
Colon cancer (CC) is one of the most prevalent cancers in the world, and chemotherapy is widely applied to combat it. However, chemotherapy drugs have severe side effects and emergence of multi drug resistance (MDR) is common. This bottlen…
View article: Tumor microenvironment penetrating chitosan nanoparticles for elimination of cancer relapse and minimal residual disease
Tumor microenvironment penetrating chitosan nanoparticles for elimination of cancer relapse and minimal residual disease Open
Chitosan and its derivatives are among biomaterials with numerous medical applications, especially in cancer. Chitosan is amenable to forming innumerable shapes such as micelles, niosomes, hydrogels, nanoparticles, and scaffolds, among oth…