Mohamed A. Yassin
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View article: Tonsillar Hypertrophy in Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: A Mini-Review
Tonsillar Hypertrophy in Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma: A Mini-Review Open
View article: Tonsillar hypertrophy as a rare presentation of chronic lymphocytic leukemia/small lymphocytic lymphoma: A mini-review
Tonsillar hypertrophy as a rare presentation of chronic lymphocytic leukemia/small lymphocytic lymphoma: A mini-review Open
Background Chronic Lymphocytic Leukemia (CLL) is a prevalent adult leukemia that primarily affects individuals over the age of 65. It is characterized by the gradual accumulation of dysfunctional B lymphocytes. While CLL usually manifests …
View article: The use of eculizumab and tocilizumab in the treatment of hyperhemolysis syndrome, a literature review
The use of eculizumab and tocilizumab in the treatment of hyperhemolysis syndrome, a literature review Open
Introduction: Hyperhemolysis Syndrome (HHS) is a rare but severe complication of red blood cell transfusion, characterized by the destruction of both the patient's and donor's red blood cells. This condition results in post-transfusion hem…
View article: Advances in polycythemia vera treatment with targeted therapies and clinical trials
Advances in polycythemia vera treatment with targeted therapies and clinical trials Open
View article: Effect of Continuous Renal Replacement Therapy Using oXiris Hemofilter in a Critically Ill Patient With Sepsis and Acute Respiratory Distress Syndrome
Effect of Continuous Renal Replacement Therapy Using oXiris Hemofilter in a Critically Ill Patient With Sepsis and Acute Respiratory Distress Syndrome Open
View article: The use of Eculizumab and Tocilizumab in the treatment of Hyperhemolysis syndrome, a comprehensive literature review
The use of Eculizumab and Tocilizumab in the treatment of Hyperhemolysis syndrome, a comprehensive literature review Open
Hyperhemolysis syndrome (HHS) is a rare but severe complication of red blood cell transfusion, characterized by the destruction of both the patient’s and donor’s red blood cells. This condition results in post-transfusion hemoglobin levels…
View article: Myelomastocytic transformation in chronic myeloid leukemia blast phase: A case report
Myelomastocytic transformation in chronic myeloid leukemia blast phase: A case report Open
Myelomastocytic leukemia (MML) presenting as a blast phase manifestation of Chronic Myeloid Leukemia (CML) is exceptionally rare, with limited documented cases in the literature. Understanding its distinct clinicopathologic features and tr…
View article: A deep dive into the surgical and pharmacological considerations of obesity in chronic myeloid leukemia: a narrative review
A deep dive into the surgical and pharmacological considerations of obesity in chronic myeloid leukemia: a narrative review Open
Background/Objectives The rising prevalence of obesity presents significant challenges in managing chronic myeloid leukemia (CML). Bariatric surgery alters the bioavailability of oral medications, necessitating tailored treatment strategie…
View article: Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-world studies
Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-world studies Open
This systematic review aims to summarise the clinical outcomes of l-glutamine, crizanlizumab, and voxelotor in the treatment of sickle cell disease (SCD) based on clinical trials and real-world data and to identify any gaps in the observat…
View article: Assessment of the awareness of rabies, rabies prophylaxis guidelines and rabies practice among physicians in Sudan: a national cross-sectional study, 2024
Assessment of the awareness of rabies, rabies prophylaxis guidelines and rabies practice among physicians in Sudan: a national cross-sectional study, 2024 Open
The study reveals significant gaps in rabies knowledge, updated rabies prophylaxis guidelines awareness, and clinical practices among Sudanese physicians, highlighting the need for targeted training and resource allocation. Strengthening h…
View article: Upfront fixed-duration treatment strategies for chronic lymphocytic leukemia in Arab populations: a position statement from the Gulf region
Upfront fixed-duration treatment strategies for chronic lymphocytic leukemia in Arab populations: a position statement from the Gulf region Open
The treatment landscape for chronic lymphocytic leukemia (CLL) has expanded dramatically over the last decade, with a wide range of effective treatments now available. Clinical management of CLL varies widely depending on patient profile, …
View article: A multicenter mixed-methods study on the effects of intermittent fasting in patients with immune thrombocytopenia receiving thrombopoietin receptor agonists
A multicenter mixed-methods study on the effects of intermittent fasting in patients with immune thrombocytopenia receiving thrombopoietin receptor agonists Open
Introduction In recent years, significant advances have been made in the treatment of immune thrombocytopenia (ITP) with the development of thrombopoietin receptor agonists (TPO-RAs). TPO-RAs are often used following the failure of prior t…
View article: WCN25-1148 MRI-BASED MEASUREMENT OF HEPATIC AND CARDIAC IRON OVERLOAD IN PATIENTS ON HEMODIALYSIS: A PROSPECTIVE COHORT STUDY
WCN25-1148 MRI-BASED MEASUREMENT OF HEPATIC AND CARDIAC IRON OVERLOAD IN PATIENTS ON HEMODIALYSIS: A PROSPECTIVE COHORT STUDY Open
View article: WCN25-1150 WHAT WE KNOW SO FAR ABOUT IRON OVERLOAD IN END-STAGE RENAL DISEASE?
WCN25-1150 WHAT WE KNOW SO FAR ABOUT IRON OVERLOAD IN END-STAGE RENAL DISEASE? Open
View article: Lessons from Beta-Thalassemia for Improving Iron Overload Monitoring and Management in Kidney Failure
Lessons from Beta-Thalassemia for Improving Iron Overload Monitoring and Management in Kidney Failure Open
Iron overload is a well-recognized complication in patients suffering from beta-thalassemia major (BTM) and end-stage renal disease (ESRD), recently known as kidney failure (KF), particularly in those who receive frequent blood transfusion…
View article: Nurse-led medication self-management intervention in the improvement of medication adherence in adult patients with multi-morbidity: A Protocol for a Feasibility Randomized controlled trial
Nurse-led medication self-management intervention in the improvement of medication adherence in adult patients with multi-morbidity: A Protocol for a Feasibility Randomized controlled trial Open
This study will offer proof of the merits of a nurse-delivered medication self-management intervention for adult patients with multimorbidity and adherence issues. If the study findings are helpful in enhancing patient adherence and health…
View article: Direct Oral Anticoagulants and Paroxysmal Nocturnal Hemoglobinuria: A Systematic Review and Update on Evidence
Direct Oral Anticoagulants and Paroxysmal Nocturnal Hemoglobinuria: A Systematic Review and Update on Evidence Open
Paroxysmal nocturnal hemoglobinuria (PNH) is a hematological disorder with an elevated risk of thrombosis. The primary cause of death in PNH patients is thrombosis. Thrombosis in patients with PNH typically occurs in unusual locations such…
View article: Caught in the Crossfire: Unmasking the Silent Renal Threats of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia
Caught in the Crossfire: Unmasking the Silent Renal Threats of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia Open
Background: Renal adverse drug reactions (ADRs) associated with tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML) are relatively rare, and there is currently no standardized protocol for their management.…
View article: Mo Passer (Mufasa): A Cost-Effective Alternative Suture-Passer Technique for Patella Fracture Fixation
Mo Passer (Mufasa): A Cost-Effective Alternative Suture-Passer Technique for Patella Fracture Fixation Open
View article: Mapping a Decade of Research: Bibliometric Analysis of Iron Overload in Chronic Kidney Disease
Mapping a Decade of Research: Bibliometric Analysis of Iron Overload in Chronic Kidney Disease Open
View article: Warm Autoimmune Hemolytic Anemia as First Presentation of Chronic Myeloid Leukemia: A Case Report
Warm Autoimmune Hemolytic Anemia as First Presentation of Chronic Myeloid Leukemia: A Case Report Open
Introduction: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the Philadelphia chromosome and uncontrolled granulocyte production. While autoimmune hemolytic anemia (AIHA) is commonly associated with lympho…
View article: Relationship between hemoglobinopathies and male infertility: a scoping review
Relationship between hemoglobinopathies and male infertility: a scoping review Open
View article: Correction: Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry
Correction: Chronic myeloid leukemia diagnosed in pregnancy: management and outcome of 87 patients reported to the European LeukemiaNet international registry Open
View article: JAK 2-Positive Diseases and Spontaneous Coronary Artery Dissection: Case Series
JAK 2-Positive Diseases and Spontaneous Coronary Artery Dissection: Case Series Open
Introduction: Chronic myeloproliferative neoplasms (MPNs) such as polycythaemia vera (PV) and essential thrombocytosis are associated with atherosclerosis and cardiovascular events, especially if JAK2 mutation is there. In rare cases, also…
View article: Thrombopoietin Receptor Agonists in Post-Hematopoietic Cell Transplantation Complicated by Prolonged Thrombocytopenia: A Comprehensive Review
Thrombopoietin Receptor Agonists in Post-Hematopoietic Cell Transplantation Complicated by Prolonged Thrombocytopenia: A Comprehensive Review Open
Hematopoietic cell transplantation (HCT) is a well-established procedure that has become a therapeutic mainstay for various hematological conditions. Prolonged thrombocytopenia following HCT is associated with a significant risk of morbidi…
View article: Prevalence of iron overload in patients with chronic kidney disease on peritoneal dialysis: A scoping review
Prevalence of iron overload in patients with chronic kidney disease on peritoneal dialysis: A scoping review Open
Background and Aims Chronic kidney disease (CKD) patients undergoing peritoneal dialysis (PD) are susceptible to complications, including iron overload, which can significantly impact their prognosis and overall health. This scoping review…
View article: Therapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL
Therapeutic strategies and treatment sequencing in patients with chronic lymphocytic leukemia: An international study of ERIC, the European Research Initiative on CLL Open
Novel small molecule inhibitors have revolutionized the treatment of chronic lymphocytic leukemia (CLL). Indeed, BTK (BTKi) and BCL2 inhibitors (BCL2i) alone or in combination with each other or other compounds have proven superior to chem…
View article: Management strategies and outcomes of thromboembolism prevention in atrial fibrillation co-existing with immune thrombocytopenia: A review of evidence
Management strategies and outcomes of thromboembolism prevention in atrial fibrillation co-existing with immune thrombocytopenia: A review of evidence Open
View article: Mitigating SSIs: focus on physical operation rooms environmental factors
Mitigating SSIs: focus on physical operation rooms environmental factors Open
Background: Surgical site infections (SSIs) are associated with increased morbidity, monetary loss and mortality. The physical aspects of the operation room (OR) including airflow, humidity, pressure, and particulate counts are essential p…
View article: Current Status and Management of Chronic Myeloid Leukemia in the Gulf Region: Survey Results and Expert Opinion
Current Status and Management of Chronic Myeloid Leukemia in the Gulf Region: Survey Results and Expert Opinion Open
Studies on chronic myeloid leukemia (CML) in the Gulf region are scarce, consisting of a survey and expert meeting that included 15 experts in 2023 which discussed CML diagnosis, testing, treatment objectives, toxicities, and discontinuati…