Eida M. Alshammari
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View article: Correction: The Neuroprotective Impact of Agomelatine in Preserving Brain Tissue Molecular Structure Against Alzheimer’s Disease Etiology
Correction: The Neuroprotective Impact of Agomelatine in Preserving Brain Tissue Molecular Structure Against Alzheimer’s Disease Etiology Open
View article: Spectroscopic investigation of the ultrasound impacts on the molecular structures of blood proteins
Spectroscopic investigation of the ultrasound impacts on the molecular structures of blood proteins Open
Low-frequency ultrasound waves (LFUWs) are applied in various medical treatments, but their effects on blood proteins’ molecular structure are not well understood. This study explores how LFUWs alter blood protein structures, utilizing ult…
View article: Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer
Mitochondrial dysfunction route as a possible biomarker and therapy target for human cancer Open
View article: Synthesis, Characterization, Antioxidant, and Anticancer Activity against Colon Cancer Cells of Some Cinnamaldehyde-Based Chalcone Derivatives
Synthesis, Characterization, Antioxidant, and Anticancer Activity against Colon Cancer Cells of Some Cinnamaldehyde-Based Chalcone Derivatives Open
The purpose of the current investigation was to produce cinammaldehyde-based chalcone derivatives (3a–k) to evaluate their potential effectiveness as antioxidant and inhibitory agents versus human Caco-2 cancer cells. The findings obtained…
View article: The role of TiO2 nanoparticles in enhancing the structural, optical, and electrical properties of PVA/PVP/CMC ternary polymer blend: nanocomposites for capacitive energy storage
The role of TiO2 nanoparticles in enhancing the structural, optical, and electrical properties of PVA/PVP/CMC ternary polymer blend: nanocomposites for capacitive energy storage Open
View article: Analysis of MIR27A (rs11671784) Variant Association with Systemic Lupus Erythematous
Analysis of MIR27A (rs11671784) Variant Association with Systemic Lupus Erythematous Open
Multiple microRNAs (miRs) are associated with systemic autoimmune disease susceptibility/phenotype, including systemic lupus erythematosus (SLE). With this work, we aimed to unravel the association of the miR-27a gene (MIR27A) rs11671784G/…
View article: HSP70 Expression Signature in Renal Cell Carcinoma: A Clinical and Bioinformatic Analysis Approach
HSP70 Expression Signature in Renal Cell Carcinoma: A Clinical and Bioinformatic Analysis Approach Open
Heat shock proteins (HSPs) are cytoprotective against stressful conditions, as in the case of cancer cell metabolism. Scientists proposed that HSP70 might be implicated in increased cancer cell survival. This study aimed to investigate the…
View article: <i>PUNISHER</i> rs12318065 C&gt;A transversion: a putative somatic driver mutation for poor prognosis in colon cancer
<i>PUNISHER</i> rs12318065 C>A transversion: a putative somatic driver mutation for poor prognosis in colon cancer Open
Objective: Colon cancer (CC) remains one of the leading causes of cancer death worldwide. Several mutations/polymorphisms have been implicated in CC development and/or progression. The role of the recently identified variants related to th…
View article: Deciphering the immunoboosting potential of macro and micronutrients in COVID support therapy
Deciphering the immunoboosting potential of macro and micronutrients in COVID support therapy Open
View article: Biophysical, Biochemical, and Molecular Docking Investigations of Anti-Glycating, Antioxidant, and Protein Structural Stability Potential of Garlic
Biophysical, Biochemical, and Molecular Docking Investigations of Anti-Glycating, Antioxidant, and Protein Structural Stability Potential of Garlic Open
Garlic has been reported to inhibit protein glycation, a process that underlies several disease processes, including chronic complications of diabetes mellitus. Biophysical, biochemical, and molecular docking investigations were conducted …
View article: Simultaneous Detection of Toxic and Heavy Metals in the Scalp Hair Samples of Smokers
Simultaneous Detection of Toxic and Heavy Metals in the Scalp Hair Samples of Smokers Open
Toxic and heavy metals are non-biodegradation pollutants in the environment that can affect human health. The levels of these metals can be analyzed with some biological materials, and they may be used to monitor changes in the human body.…
View article: Mitochondrial Dysfunction: A Notable Contributor to the Progression of Alzheimer's and Parkinson's Disease
Mitochondrial Dysfunction: A Notable Contributor to the Progression of Alzheimer's and Parkinson's Disease Open
View article: WITHDRAWN: Common NLRP3 inflammasome inhibitors and Covid-19: Divide and Conquer
WITHDRAWN: Common NLRP3 inflammasome inhibitors and Covid-19: Divide and Conquer Open
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our…
View article: Garlic Extract: Inhibition of Biochemical and Biophysical Changes in Glycated HSA
Garlic Extract: Inhibition of Biochemical and Biophysical Changes in Glycated HSA Open
Glycation of various biomolecules contributes to structural changes and formation of several high molecular weight fluorescent and non-fluorescent, advanced glycation end products (AGEs). AGEs and glycation are involved in various health c…
View article: Association of microRNA-34a rs2666433 (A/G) Variant with Systemic Lupus Erythematosus in Female Patients: A Case-Control Study
Association of microRNA-34a rs2666433 (A/G) Variant with Systemic Lupus Erythematosus in Female Patients: A Case-Control Study Open
Several microRNAs (miRNAs) are associated with autoimmune disease susceptibility and phenotype, including systemic lupus erythematosus (SLE). We aimed to explore for the first time the role of the miRNA-34a gene (MIR34A) rs2666433A > G var…
View article: Arginine vasopressin and pathophysiology of COVID-19: An innovative perspective
Arginine vasopressin and pathophysiology of COVID-19: An innovative perspective Open
View article: Enhanced Antibacterial Potential of Amoxicillin against Helicobacter pylori Mediated by Lactobionic Acid Coated Zn-MOFs
Enhanced Antibacterial Potential of Amoxicillin against Helicobacter pylori Mediated by Lactobionic Acid Coated Zn-MOFs Open
H. pylori (Helicobacter pylori) causes a common chronic infectious disease and infects around 4.4 billion people worldwide. H. pylori was classified as a member of the primary class of stomach cancer (stomach adenocarcinoma). Hence, this s…
View article: Covid-19 and development of heart failure: mystery and truth
Covid-19 and development of heart failure: mystery and truth Open
View article: Mitochondrial Dysfunction: a Notable Contributor to the Progression of Alzheimer’s & Parkinson’s Disease
Mitochondrial Dysfunction: a Notable Contributor to the Progression of Alzheimer’s & Parkinson’s Disease Open
Mitochondrial dysfunctions remained a pivotal mechanism in manifold neurodegenerative diseases. Mitochondrial homeostasis within the cell is an essential aspect of cell biology. Mitochondria which is also known as the power-generating set …
View article: Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment
Impacting the Remedial Potential of Nano Delivery-Based Flavonoids for Breast Cancer Treatment Open
Breast cancer persists as a diffuse source of cancer despite persistent detection and treatment. Flavonoids, a type of polyphenol, appear to be a productive option in the treatment of breast cancer, because of their capacity to regulate th…
View article: Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets
Curcumin Nanoparticles as Promising Therapeutic Agents for Drug Targets Open
Curcuma longa is very well-known medicinal plant not only in the Asian hemisphere but also known across the globe for its therapeutic and medicinal benefits. The active moiety of Curcuma longa is curcumin and has gained importance in vario…
View article: The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections
The Rise of SARS-CoV-2 Variants and the Role of Convalescent Plasma Therapy for Management of Infections Open
Novel therapies for the treatment of COVID-19 are continuing to emerge as the SARS-Cov-2 pandemic progresses. PCR remains the standard benchmark for initial diagnosis of COVID-19 infection, while advances in immunological profiling are gui…
View article: Selective Oxidation of Cinnamyl Alcohol to Cinnamaldehyde over Functionalized Multi-Walled Carbon Nanotubes Supported Silver-Cobalt Nanoparticles
Selective Oxidation of Cinnamyl Alcohol to Cinnamaldehyde over Functionalized Multi-Walled Carbon Nanotubes Supported Silver-Cobalt Nanoparticles Open
The selective oxidation of alcohols to aldehydes has attracted a lot of attention because of its potential use in agrochemicals, fragrances, and fine chemicals. However, due to homogenous catalysis, low yield, low selectivity, and hazardou…
View article: Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives
Herbal drugs and natural bioactive products as potential therapeutics: A review on pro-cognitives and brain boosters perspectives Open
View article: Biologically Active α-Amino Amide Analogs and γδ T Cells—A Unique Anticancer Approach for Leukemia
Biologically Active α-Amino Amide Analogs and γδ T Cells—A Unique Anticancer Approach for Leukemia Open
Advanced stage cancers are aggressive and difficult to treat with mono-therapeutics, substantially decreasing patient survival rates. Hence, there is an urgent need to develop unique therapeutic approaches to treat cancer with superior pot…
View article: Sub-lethal effects of organophosphates and synthetic pyrethroid insecticides on muscle tissue transaminases of Oreochromis niloticus in vivo
Sub-lethal effects of organophosphates and synthetic pyrethroid insecticides on muscle tissue transaminases of Oreochromis niloticus in vivo Open
View article: Antioxidants-Related Superoxide Dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPX), Glutathione-S-Transferase (GST), and Nitric Oxide Synthase (NOS) Gene Variants Analysis in an Obese Population: A Preliminary Case-Control Study
Antioxidants-Related Superoxide Dismutase (SOD), Catalase (CAT), Glutathione Peroxidase (GPX), Glutathione-S-Transferase (GST), and Nitric Oxide Synthase (NOS) Gene Variants Analysis in an Obese Population: A Preliminary Case-Control Study Open
Oxidative stress and antioxidants play an important role in obesity etiopathology. Genetic variants, including single nucleotide polymorphisms (SNPs) of the antioxidant-related genes, may impact disease risk in several populations. This pr…
View article: Optimization of methods for peripheral blood mononuclear cells isolation and expansion of human gamma delta T cells
Optimization of methods for peripheral blood mononuclear cells isolation and expansion of human gamma delta T cells Open
Human Vγ9/Vδ2 T cells (γδ T cells) are immune surveillance cells both in innate and adaptive immunity and are a possible target for anticancer therapies, which can induce immune responses in a variety of cancers. Small non-peptide antigens…
View article: Covid-19-Induced Dysautonomia: A Menace of Sympathetic Storm
Covid-19-Induced Dysautonomia: A Menace of Sympathetic Storm Open
Among the plethora of debilitating neurological disorders of COVID-19 syndrome in survivors, the scope of SARS-CoV-2-induced dysautonomia (DNS) is yet to be understood, though the implications are enormous. Herein, we present an inclusive …
View article: Preclinical prediction of phytochemicals identified from cannabis as novel inhibitors of TEX 11, DHCR24, and CatSper 1 in fertility drug design
Preclinical prediction of phytochemicals identified from cannabis as novel inhibitors of TEX 11, DHCR24, and CatSper 1 in fertility drug design Open
Medicinally, cannabis is gaining popularity and acceptance around the world despite public concerns regarding its legality. The wide range of phytochemical found in the Cannabis sativa (C. sativa) plant predisposes it to use in the treatme…