Shaum Kabadi
YOU?
Author Swipe
View article: EFFICACY AND SAFETY OF BELUMOSUDIL VERSUS BEST AVAILABLE THERAPY FOR THE TREATMENT OF CHRONIC GRAFT-VERSUS-HOST DISEASE IN THE US POPULATION
EFFICACY AND SAFETY OF BELUMOSUDIL VERSUS BEST AVAILABLE THERAPY FOR THE TREATMENT OF CHRONIC GRAFT-VERSUS-HOST DISEASE IN THE US POPULATION Open
View article: Efficacy and Safety of Belumosudil as Compared with Best Available Therapy for the Treatment of cGVHD in the US
Efficacy and Safety of Belumosudil as Compared with Best Available Therapy for the Treatment of cGVHD in the US Open
Belumosudil was FDA-approved in the United States (US) for the treatment of relapsed/refractory chronic graft-versus-host disease (cGVHD) based on a randomized phase II trial comparing two belumosudil doses. The efficacy and safety of belu…
View article: Real‐World Health Care Resource Utilization and Costs Associated With First‐Line Dronedarone Versus First‐Line Ablation in Adults With Atrial Fibrillation
Real‐World Health Care Resource Utilization and Costs Associated With First‐Line Dronedarone Versus First‐Line Ablation in Adults With Atrial Fibrillation Open
Background Rhythm control therapy with antiarrhythmic drugs (AADs) or catheter ablation is recommended for treatment of atrial fibrillation (AF). The impact of first‐line AAD therapy (including dronedarone) or ablation on health care resou…
View article: Dronedarone vs Sotalol Among Patients With Atrial Fibrillation
Dronedarone vs Sotalol Among Patients With Atrial Fibrillation Open
In this retrospective meta-analysis, dronedarone exhibited significantly lower rates of CV hospitalization and ventricular arrhythmias compared with sotalol. These findings provide real-world evidence to support selection of the most appro…
View article: Health Care Resource Utilization With Dronedarone Versus Sotalol Following Catheter Ablation in Adults With Atrial Fibrillation
Health Care Resource Utilization With Dronedarone Versus Sotalol Following Catheter Ablation in Adults With Atrial Fibrillation Open
Background Clinical trials support dronedarone use for atrial fibrillation (AF) following catheter ablation (CA); however, comparative data on health care resource utilization (HCRU) with other antiarrhythmic drugs are lacking. Methods Ret…
View article: PO-01-133 REAL-WORLD COMPARISON OF DRONEDARONE VS. SOTALOL IN ANTI-ARRHYTHMIC DRUG NAÏVE PATIENTS WITH ATRIAL FIBRILLATION
PO-01-133 REAL-WORLD COMPARISON OF DRONEDARONE VS. SOTALOL IN ANTI-ARRHYTHMIC DRUG NAÏVE PATIENTS WITH ATRIAL FIBRILLATION Open
View article: Cluster analysis of kidney function decline among males with Fabry disease in a large United States electronic health records database
Cluster analysis of kidney function decline among males with Fabry disease in a large United States electronic health records database Open
Background Fabry disease (FD) is an X-linked lysosomal storage disorder caused by deficient α-galactosidase A activity. The spectrum of disease includes phenotypes ranging from “classic” to “later-onset,” with varying kidney disease progre…
View article: Epidemiologic patterns of biliary tract cancer in the United States: 2001–2015
Epidemiologic patterns of biliary tract cancer in the United States: 2001–2015 Open
View article: HARmonized Protocol Template to Enhance Reproducibility of hypothesis evaluating real‐world evidence studies on treatment effects: A good practices report of a joint ISPE/ISPOR task force
HARmonized Protocol Template to Enhance Reproducibility of hypothesis evaluating real‐world evidence studies on treatment effects: A good practices report of a joint ISPE/ISPOR task force Open
Problem Ambiguity in communication of key study parameters limits the utility of real‐world evidence (RWE) studies in healthcare decision‐making. Clear communication about data provenance, design, analysis, and implementation is needed. Th…
View article: HARmonized Protocol Template to Enhance Reproducibility of Hypothesis Evaluating Real-World Evidence Studies on Treatment Effects: A Good Practices Report of a Joint ISPE/ISPOR Task Force
HARmonized Protocol Template to Enhance Reproducibility of Hypothesis Evaluating Real-World Evidence Studies on Treatment Effects: A Good Practices Report of a Joint ISPE/ISPOR Task Force Open
The HARmonized Protocol Template to Enhance Reproducibility (HARPER) helps to create a shared understanding of intended scientific decisions through a common text, tabular and visual structure. The template provides a set of core recommend…
View article: Additional file 2 of Epidemiologic patterns of biliary tract cancer in the United States: 2001–2015
Additional file 2 of Epidemiologic patterns of biliary tract cancer in the United States: 2001–2015 Open
Additional file 2. Original survival data for the Asian/Pacific Islander population with distant BTC and the SEER*Stat Survival Session.
View article: Worldwide Incidence and Mortality of Biliary Tract Cancer
Worldwide Incidence and Mortality of Biliary Tract Cancer Open
View article: Overall survival, adverse events, and economic burden in patients with chronic lymphocytic leukemia receiving systemic therapy: Real‐world evidence from the medicare population
Overall survival, adverse events, and economic burden in patients with chronic lymphocytic leukemia receiving systemic therapy: Real‐world evidence from the medicare population Open
Background Information on overall survival (OS) and adverse events (AEs) in patients with chronic lymphocytic leukemia (CLL) is mostly available from clinical trials. We therefore conducted a population‐based retrospective cohort study to …
View article: Treatment patterns and outcomes among mantle cell lymphoma patients treated with ibrutinib in the United States: a retrospective electronic medical record database and chart review study
Treatment patterns and outcomes among mantle cell lymphoma patients treated with ibrutinib in the United States: a retrospective electronic medical record database and chart review study Open
Summary The experience of patients with mantle cell lymphoma (MCL) in community oncology practices, including reasons for treatment discontinuation, is sparse. This retrospective study sought to elucidate treatment patterns and outcomes of…
View article: Correction to: Real-World Treatment Patterns, Adverse Events, Resource Use, and Costs Among Commercially Insured, Younger Patients with Chronic Lymphocytic Leukemia in the USA: A Retrospective Cohort Study
Correction to: Real-World Treatment Patterns, Adverse Events, Resource Use, and Costs Among Commercially Insured, Younger Patients with Chronic Lymphocytic Leukemia in the USA: A Retrospective Cohort Study Open
View article: The economic burden of systemic lupus erythematosus in commercially- and medicaid-insured populations in the United States
The economic burden of systemic lupus erythematosus in commercially- and medicaid-insured populations in the United States Open
View article: Adverse event rates and economic burden associated with purine nucleoside analogs in patients with hairy cell leukemia: a US population-retrospective claims analysis
Adverse event rates and economic burden associated with purine nucleoside analogs in patients with hairy cell leukemia: a US population-retrospective claims analysis Open
View article: Matching-adjusted Indirect Comparisons of the Efficacy and Safety of Acalabrutinib Versus Other Targeted Therapies in Relapsed/Refractory Mantle Cell Lymphoma
Matching-adjusted Indirect Comparisons of the Efficacy and Safety of Acalabrutinib Versus Other Targeted Therapies in Relapsed/Refractory Mantle Cell Lymphoma Open
View article: Table of Contents
Table of Contents Open
View article: Treatment patterns, adverse events, healthcare resource use and costs among commercially insured patients with mantle cell lymphoma in the United States
Treatment patterns, adverse events, healthcare resource use and costs among commercially insured patients with mantle cell lymphoma in the United States Open
Introduction There are limited data on treatment patterns, adverse events (AEs), and economic burden in younger, commercially insured patients treated for mantle cell lymphoma (MCL). Methods Adults with ≥1 treatment for MCL between 1 Novem…
View article: Treatment patterns, adverse events, and economic burden in a privately insured population of patients with chronic lymphocytic leukemia in the United States
Treatment patterns, adverse events, and economic burden in a privately insured population of patients with chronic lymphocytic leukemia in the United States Open
Introduction Contemporary data describing treatment patterns, adverse events (AEs), and outcomes in patients with chronic lymphocytic leukemia (CLL) in clinical practice are lacking. We conducted a retrospective cohort study and assessed t…
View article: Impact of dosing frequency (once daily or twice daily) on patient adherence to oral targeted therapies for hematologic malignancies: a retrospective cohort study among managed care enrollees
Impact of dosing frequency (once daily or twice daily) on patient adherence to oral targeted therapies for hematologic malignancies: a retrospective cohort study among managed care enrollees Open
Purpose Existing studies evaluating patient adherence to oral targeted therapies such as tyrosine kinase inhibitors focus on small populations with single malignancies. This study evaluated patterns of use of oral agents in a larger popula…
View article: Adverse events, resource use, and economic burden associated with mantle cell lymphoma: a real-world assessment of privately insured patients in the United States
Adverse events, resource use, and economic burden associated with mantle cell lymphoma: a real-world assessment of privately insured patients in the United States Open
In view of recent therapeutic advances in mantle cell lymphoma (MCL), the aim of this retrospective cohort analysis was to assess treatment patterns, adverse events (AEs), resource utilization, and health care costs in patients with MCL in…
View article: Healthcare resource utilization and costs associated with long-term corticosteroid exposure in patients with systemic lupus erythematosus
Healthcare resource utilization and costs associated with long-term corticosteroid exposure in patients with systemic lupus erythematosus Open
Objective To evaluate the association between exposure to oral corticosteroids and future healthcare resource utilization and costs for patients with systemic lupus erythematosus. Methods Adults diagnosed with systemic lupus erythematosus …
View article: Budget impact of adding lesinurad for second-line treatment of gout: a US health plan perspective
Budget impact of adding lesinurad for second-line treatment of gout: a US health plan perspective Open
Aim: To estimate budget impact of adopting lesinurad as add-on to allopurinol for urate-lowering therapy in gout. Methods: A budget impact model was developed for a US payer perspective, using a Markov model to estimate costs, survival and…
View article: Prevalence, treatment patterns, and healthcare resource utilization in Medicare and commercially insured non-dialysis-dependent chronic kidney disease patients with and without anemia in the United States
Prevalence, treatment patterns, and healthcare resource utilization in Medicare and commercially insured non-dialysis-dependent chronic kidney disease patients with and without anemia in the United States Open
More research is necessary to determine best approaches to anemia management in CKD.
View article: FRI0728 Osteoarthritis and gout: real-world evidence evaluating patient characteristics, treatment patterns, and healthcare utilization
FRI0728 Osteoarthritis and gout: real-world evidence evaluating patient characteristics, treatment patterns, and healthcare utilization Open
View article: Utilization of Positive and Negative Controls to Examine Comorbid Associations in Observational Database Studies
Utilization of Positive and Negative Controls to Examine Comorbid Associations in Observational Database Studies Open
Background: Opportunities to leverage observational data for precision medicine research are hampered by underlying sources of bias and paucity of methods to handle resulting uncertainty. We outline an approach to account for bias in ident…
View article: Predictive Model Of Parkinson’s Disease In Large Electronic Health Records Database
Predictive Model Of Parkinson’s Disease In Large Electronic Health Records Database Open
View article: Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies
Body Mass Index and Risk of Nonalcoholic Fatty Liver Disease: Two Electronic Health Record Prospective Studies Open
These data quantify the consistent and strong relationships between BMI and prospectively recorded diagnoses of NAFLD/NASH and emphasize the importance of weight reduction strategies for prevention and management of NAFLD.