Akash Shukla
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View article: Comparative In vitro Analysis of Resorbable vs Titanium Miniplates in Simulated Mandibular Fracture Models
Comparative In vitro Analysis of Resorbable vs Titanium Miniplates in Simulated Mandibular Fracture Models Open
Background: The management of mandibular fractures traditionally involves the use of titanium miniplates for internal fixation. However, resorbable plating systems offer potential advantages, such as eliminating the need for second-stage r…
View article: Probiotic Blend of <scp> <i>Lactobacillus acidophilus</i> </scp> LA‐5 and <scp> <i>Bifidobacterium animalis</i> </scp> ssp. <i>Lactis</i> BB‐12 in Non‐constipated Irritable Bowel Syndrome: A Double‐Blind Randomized Placebo‐Controlled Trial
Probiotic Blend of <span> <i>Lactobacillus acidophilus</i> </span> LA‐5 and <span> <i>Bifidobacterium animalis</i> </span> ssp. <i>Lactis</i> BB‐12 in Non‐constipated Irritable Bowel Syndrome: A Double‐Blind Randomized Placebo‐Controlled Trial Open
Background As dysregulated gut microbiota is known in irritable bowel syndrome (IBS) and probiotics may improve it, we investigated the efficacy and safety of a combination probiotic, Lactobacillus acidophilus LA‐5 and Bifidobacterium anim…
View article: Towards improved neonatal care: Developing reference intervals for biochemical parameters in umbilical cord blood: An Indian study
Towards improved neonatal care: Developing reference intervals for biochemical parameters in umbilical cord blood: An Indian study Open
BACKGROUND The reference ranges for biochemical parameters can fluctuate due to factors like altitude, age, gender, and socioeconomic conditions. These values are crucial for interpreting laboratory data and guide clinical treatment decisi…
View article: Portal cavernoma cholangiopathy: A systematic review of current understanding, clinical significance, and management
Portal cavernoma cholangiopathy: A systematic review of current understanding, clinical significance, and management Open
Portal cavernoma cholangiopathy (PCC) is a rare condition characterized by abnormalities of the intrahepatic and extrahepatic bile ducts and the gallbladder, resulting from long-standing chronic portal vein thrombosis (cPVT). These vascula…
View article: Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity
Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity Open
Common Variable Immunodeficiency (CVID) is a heterogeneous disorder characterized by impaired antibody production and recurrent infections. In this study we investigated the clinical and immunological features of CVID in Indian patients an…
View article: Phantom tumour: inflammatory pseudotumour of the liver: a rare case report and review of literature
Phantom tumour: inflammatory pseudotumour of the liver: a rare case report and review of literature Open
Introduction: The term ‘inflammatory pseudotumour’ (IPT) denotes a heterogeneous group of mass-forming lesions.1 IPT most commonly occurs in the lung, but it can be found in other locations, including the central nervous system, kidneys, o…
View article: Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia
Acute-on-chronic liver failure (ACLF): the ‘Kyoto Consensus’—steps from Asia Open
Acute-on-chronic liver failure (ACLF) is a condition associated with high mortality in the absence of liver transplantation. There have been various definitions proposed worldwide. The first consensus report of the working party of the Asi…
View article: MCMC Importance Sampling via Moreau-Yosida Envelopes
MCMC Importance Sampling via Moreau-Yosida Envelopes Open
Non-differentiable priors are standard in modern parsimonious Bayesian models. Lack of differentiability, however, precludes gradient-based Markov chain Monte Carlo (MCMC) for posterior sampling. Recently proposed proximal MCMC approaches …
View article: Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity
Common Variable Immunodeficiency Disorder: A Decade of Insights from a Cohort of 150 Patients in India and the Use of Machine Learning Algorithms to Predict Severity Open
Common Variable Immunodeficiency (CVID) is a heterogeneous disorder characterized by impaired antibody production and recurrent infections. In this study we investigated the clinical and immunological features of CVID in Indian patients an…
View article: Evaluation and Management of Unresectable Hepatocellular Carcinoma: Multidisciplinary Indian Consensus Statements from a Delphi Panel
Evaluation and Management of Unresectable Hepatocellular Carcinoma: Multidisciplinary Indian Consensus Statements from a Delphi Panel Open
India, like many parts of Asia, likely faces a high burden of hepatocellular carcinoma (HCC), though large-scale data on etiology, presentation, and outcomes are lacking. There appears to be a predominance of unresectable, advanced-stage H…
View article: Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome
Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome Open
BACKGROUND There is scant literature on hepatocellular carcinoma (HCC) in patients with Budd-Chiari syndrome (BCS). AIM To assess the magnitude, clinical characteristics, feasibility, and outcomes of treatment in BCS-HCC. METHODS A total o…
View article: Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients Open
The relationship between ammonia and liver-related complications (LRCs) in acute-on-chronic liver failure (ACLF) patients is not clearly established. This study aimed to evaluate the association between ammonia levels and LRCs in patients …
View article: Obstacle Avoiding Robot using Arduino Sensor
Obstacle Avoiding Robot using Arduino Sensor Open
The project is designed to build an obstacle avoidance robotic vehicle using ultrasonic sensors for its movement. Arduino is used to achieve the desired operation. A robot is a machine that can perform tasks automatically or with guidance.…
View article: Retained Biliary Plastic Stents: Clinical Presentation, Complications, and Management
Retained Biliary Plastic Stents: Clinical Presentation, Complications, and Management Open
Background Biliary plastic stent (PS) mandates timely removal or replacement. The coronavirus disease 2019 (COVID-19) pandemic had affected the accessibility to medical therapy resulting in delay. We evaluated the burden of retained biliar…
View article: Endoscopic Ultrasound-Guided Multiple Actuation Liver Biopsy Has Better Adequacy and Lesser Pain with Equal Safety Profile Compared to Percutaneous Route
Endoscopic Ultrasound-Guided Multiple Actuation Liver Biopsy Has Better Adequacy and Lesser Pain with Equal Safety Profile Compared to Percutaneous Route Open
Aims: Endoscopic ultrasound-guided liver biopsy (EUS-LB) has emerged as an alternative to the percutaneous route (PC-LB). Multiple actuation has the potential to increase yield of specimen. We aimed at comparing sample adequacy and safety …
View article: Clinical Impact of Routine Computed Tomography Esophagogram after Peroral Endoscopic Myotomy for Esophageal Motility Disorders
Clinical Impact of Routine Computed Tomography Esophagogram after Peroral Endoscopic Myotomy for Esophageal Motility Disorders Open
Aim: Peroral endoscopic myotomy (POEM) of the lower esophageal sphincter is an established treatment modality for various esophageal motility disorders, especially achalasia cardia. Although safe it can be associated with major and minor a…
View article: Modified Endoscopic Ultrasound-Guided Liver Biopsy in Patients with or without Cirrhosis: Comparative Analysis of Adequacy, Safety, and Technical Determinants
Modified Endoscopic Ultrasound-Guided Liver Biopsy in Patients with or without Cirrhosis: Comparative Analysis of Adequacy, Safety, and Technical Determinants Open
Aims: Endoscopic ultrasound-guided liver biopsy (EUS-LB) for tissue acquisition in patients with cirrhosis has not been studied. We used a modified technique to compare the adequacy, safety and technical determinants with non-cirrhotics.
View article: Lower Gastrointestinal Bleed in Children: Safety, Utility, and Yield of Colonoscopy: an Experience from a Large Tertiary Referral Endoscopy Center
Lower Gastrointestinal Bleed in Children: Safety, Utility, and Yield of Colonoscopy: an Experience from a Large Tertiary Referral Endoscopy Center Open
Objective: There is paucity of data on lower gastrointestinal bleed (LGIB) in the pediatric population. We aimed to retrospectively review the endoscopy findings in patients younger than 18 years, presenting with lower gastrointestinal (GI…
View article: Outcome of individuals with alcoholic cirrhosis hospitalized with first decompensation and their predictors
Outcome of individuals with alcoholic cirrhosis hospitalized with first decompensation and their predictors Open
Background & objectives: Alcohol is one of most common aetiologies of cirrhosis and decompensated cirrhosis is linked to higher morbidity and death rates. This study looked at the outcomes and mortality associated risk variables of individ…
View article: Novel method for refractory tracheoesophageal fistula closure: modified polydioxanone suture mesh with fibrin glue
Novel method for refractory tracheoesophageal fistula closure: modified polydioxanone suture mesh with fibrin glue Open
Results-Successful closure of TEF was achieved with PDS suture mesh and three sessions of fibrin glue application over total treatment duration of 8 weeks. •Conclusions-Modified PDS suture mesh with fibrin glue application offers an additi…