Mohit Sindhani
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View article: Clinical and histological predictors of treatment outcomes in primary urethral carcinoma
Clinical and histological predictors of treatment outcomes in primary urethral carcinoma Open
In this large North American cohort, nodal involvement predicted worse survival, while nonurothelial histology was linked to shorter recurrence-free survival. These findings support multidisciplinary care and highlight the need for prospec…
View article: Bladder cancer microbiome and its association with chemoresponse
Bladder cancer microbiome and its association with chemoresponse Open
Background The microbiome is widely known to cause come types of cancer, modify cancer biology, and impact therapeutic efficacy. Despite the urinary microbiome being one of the most clinically significant microbiomes in human health, it is…
View article: Genetic susceptibility and environmental risk factors in bladder cancer: Evidence from the UK biobank
Genetic susceptibility and environmental risk factors in bladder cancer: Evidence from the UK biobank Open
Purpose This study aims to identify specific genotypes within the UK Biobank (UKB) cohort contributing to a genetic predisposition for bladder cancer (UBC). It highlighted the impact of environmental exposures and the broader role of certa…
View article: Beyond Citations: Exploring Gender and Racial Gaps in Urology Publications Through Citation and Altmetric Analysis
Beyond Citations: Exploring Gender and Racial Gaps in Urology Publications Through Citation and Altmetric Analysis Open
This study examined how often urology research papers are cited based on the gender and race of the authors. We found that studies led by women are cited less frequently than those led by men, despite receiving more online attention and fu…
View article: Gender Disparities in Citations and Altmetric Attention Score in Oncology
Gender Disparities in Citations and Altmetric Attention Score in Oncology Open
PURPOSE Altmetric Attention Score (AAS) is a measure of the quantity of attention that a scholarly work receives, and evidence about gender gaps in AAS in oncology is lacking. Our objective was to analyze potential disparities in the AAS w…
View article: Financial Distress in Genitourinary Cancer: Insights From CDC National Health Interview Survey
Financial Distress in Genitourinary Cancer: Insights From CDC National Health Interview Survey Open
PURPOSE This study leverages CDC National Health Interview Survey data to examine Financial Distress (FD) among genitourinary (GU) cancer survivors, specifically prostate cancer (PC), kidney cancer (KC), and bladder cancer (BC). It investi…
View article: FIGURE 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Analysis of SCFA concentrations in relation to chemotherapy response. Top: Mean SCFA concentrations in plasma and stool of patients with bladder cancer categorized by NAC response status (CR vs. NR), showing no significant differences. Bot…
View article: Supplementary Figure 2 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 2 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 2: Patient Recruitment Flow Chart Flowchart illustrating the step-by-step recruitment process of bladder cancer patients, detailing inclusion and exclusion criteria and subsequent enrollment stages
View article: Supplementary Figure 7 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 7 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 7: Gut Microbiome Changes in Partners of Bladder Cancer PatientsA: Stacked bar chart representing the relative abundances of key bacterial genera before, during, and after the chemotherapy periods in partners of patien…
View article: Supplementary Figure 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 6: Gut Microbiome Dynamics During Neoadjuvant ChemotherapyA: Relative abundance of major bacterial genera before, during, and after chemotherapy. Each color represents a different genus, with patient-specific changes h…
View article: FIGURE 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Analysis of SCFA concentrations in relation to chemotherapy response. Top: Mean SCFA concentrations in plasma and stool of patients with bladder cancer categorized by NAC response status (CR vs. NR), showing no significant differences. Bot…
View article: Supplementary Figure 7 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 7 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 7: Gut Microbiome Changes in Partners of Bladder Cancer PatientsA: Stacked bar chart representing the relative abundances of key bacterial genera before, during, and after the chemotherapy periods in partners of patien…
View article: FIGURE 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Microbial composition variance in relation to chemotherapy response in patients with bladder cancer. A, Proportional representation of the GM's phylogenetic composition in patients showing CR versus NR to NAC (Also depicted in C<…
View article: Supplementary Figure 8 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 8 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 8: Microbial Composition Differences in Mice Exposed to BBN Versus WaterWater Group:A: Alpha diversity indices (ACE, Chao1, Shannon) plotted over multiple time points (0, 6, 12, 16-22 weeks), showing variations in micr…
View article: Supplementary Figure 1 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 1 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 1: Overview of Sample Collection and Experimental Setup Diagram outlining the protocols for human fecal sample collection across various time points during chemotherapy in bladder cancer patients, accompanied by the se…
View article: FIGURE 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Predictive efficacy of microbial biomarkers on NAC response. A, Graphical representation of model performance metrics (out of bag score, sensitivity, NPV, specificity, PPV, AUC score) across iterations, evaluating the robustness of …
View article: FIGURE 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Predictive efficacy of microbial biomarkers on NAC response. A, Graphical representation of model performance metrics (out of bag score, sensitivity, NPV, specificity, PPV, AUC score) across iterations, evaluating the robustness of …
View article: Supplementary Figure 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 4: Sex-Specific Microbiome Diversity in Bladder Cancer and Control GroupsA: Stacked bar plot showing the phylogenetic composition of bacterial taxa at the genus level in male and female cohorts of bladder cancer patien…
View article: Supplementary Figure 9 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 9 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 9: Microbial Composition Variability by Sex in BBN-Exposed MiceBBN Gender Female:A: Alpha diversity indices (ACE, Chao1, Shannon) across different time points (0, 6, 12, 16-22 weeks), showing variations in microbial di…
View article: Supplementary Figure 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 6: Gut Microbiome Dynamics During Neoadjuvant ChemotherapyA: Relative abundance of major bacterial genera before, during, and after chemotherapy. Each color represents a different genus, with patient-specific changes h…
View article: Supplementary Figure 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 3 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 3: Imaging of Murine Urothelial Cancer CT urography and ultrasound images displaying bladder tumors induced by BBN in mice, shown in both axial and coronal views, with tumors highlighted by arrows.
View article: FIGURE 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 6 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Longitudinal microbiota analysis in a murine model exposed to BBN versus water. A, Shannon diversity index measures across different timepoints (0, 6, 12, 16–22 weeks) showing changes in alpha diversity in mice treated with BBN comp…
View article: Supplementary Figure Legends from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure Legends from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure Legends
View article: FIGURE 2 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
FIGURE 2 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Correlations between participant demographics, clinical characteristics, and microbial taxa. A, Plots illustrating the impact of smoking status and age on specific microbial taxa, annotated with statistical significance and effect s…
View article: Supplementary Data from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Data from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplemental Data
View article: Supplementary Figure 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 5 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 5: Community Grouping Based on Gut Microbiome Response StatusA: Hierarchical clustering identifying two distinct microbial community groups among bladder cancer patients (CR and NR).B and C: Alpha and beta diversity an…
View article: Supplementary Figure 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 4 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 4: Sex-Specific Microbiome Diversity in Bladder Cancer and Control GroupsA: Stacked bar plot showing the phylogenetic composition of bacterial taxa at the genus level in male and female cohorts of bladder cancer patien…
View article: Supplementary Figure Legends from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure Legends from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure Legends
View article: Supplementary Figure 8 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Figure 8 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Supplementary Figure 8: Microbial Composition Differences in Mice Exposed to BBN Versus WaterWater Group:A: Alpha diversity indices (ACE, Chao1, Shannon) plotted over multiple time points (0, 6, 12, 16-22 weeks), showing variations in micr…
View article: Supplementary Table 1 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation
Supplementary Table 1 from Role of Gut Microbiome in Neoadjuvant Chemotherapy Response in Urothelial Carcinoma: A Multi-institutional Prospective Cohort Evaluation Open
Patient Characteristics