Explanipedia

Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf<sup>®</sup>) in kidney transplantation: a phase IV study Open

Behzad Einollahi, Mohsen Nafar, Mohammad Javanbakht, Amirhesam Alirezaei, Jalal Azmandian , et al. · 2025

Background Transplant recipients are given an immunosuppressive regimen such as tacrolimus to prevent organ rejection. Suprotac® is a generic tacrolimus that is utilized in kidney transplantation regimen in Iran. This post-market study was…

Desensitization Strategies in Kidney Transplantation Open

Mohsen Nafar, Shiva Samavat · 2024

Desensitization protocols offer a promising approach to increase the pool of kidney transplant recipients by enabling transplantation with HLA-incompatible kidneys. This chapter explores the rationale for desensitization, considering the g…

Intraperitoneal Injection of Graphene Oxide Nanoparticle Accelerates Stem Cell Therapy Effects on Acute Kidney Injury [Retraction] Open

Tahereh Foroutan, Mohsen Nafar, Elaheh Motamedi · 2024

[This retracts the article DOI: 10.2147/SCCAA.S212087.].

Association Between the Chemical Composition of Saliva and Serum in Patients with Kidney Failure Open

Alireza Rajolani, Arezoo Alaee, Mohsen Nafar, Mohammadjavad Kharazifard, Kimia Ghods · 2024

Background: End-Stage Renal Disease (ESRD) is a severe nephrological condition that can lead to permanent kidney damage. Therefore, early disease diagnosis is key to preventing casualties. The gold standard method of diagnosis tends to eva…

Using Clustering to Strengthen Decision Diagram Bounds for Discrete Optimization Open

Mohsen Nafar, Michael Römer · 2024

Offering a generic approach to obtaining both upper and lower bounds, decision diagrams (DDs) are becoming an increasingly important tool for solving discrete optimization problems. In particular, they provide a powerful and often compleme…

Identification of predictive biomarkers of response to treatment in patients with antibody mediated rejection: a case –control proteomics study Open

Mohsen Nafar, Shiva Samavat, Shiva Kalantari, Leonard J. Foster, Kyung‐Mee Moon , et al. · 2024

Background: Timely detection and appropriate treatment of Acute antibody mediated rejection (AMR) would affect long-term survival of allograft. This study was designed to discover non-invasive biomarkers in prediction of response to therap…

Sinopharm (BBIBP-CorV) COVID-19 Vaccination in Hemodialysis Patients and Healthy Individuals: 1-year Effectiveness and Immunogenicity Immunization of Sinopharm Vaccine against COVID-19 Open

Seyed Amir Ahmad Safavi‐Naini, Yasaman Baseri, Azadeh Ahmadi Koomleh, Niloofar Fakour, Aryan Salahi‐Niri , et al. · 2024

Introduction: The COVID-19 pandemic has presented significant challenges for immunocompromised populations, particularly hemodialysis patients, who are at an elevated risk for severe outcomes. Vaccination remains a critical strategy to mit…

A Urinary Proteomics Approach to Predict Treatment Response in Acute Antibody-Mediated Rejection Open

Somaye-Sadat Heidari, Nooshin Dalili, Shiva Samavat, Shiva Kalantari, Leonard J. Foster , et al. · 2023

Acute antibody-mediated rejection (AMR) is a severe complication affecting kidney allografts' long-term survival. Timely detection and appropriate treatment of AMR are crucial for improving graft outcomes. This study aimed to discover non-…

Identification of Potential Predictive and Diagnostic Urinary Biomarkers for Acute Rejection in Renal Transplant Recipients: A Proteomics Study Open

Mohsen Nafar, Shiva Samavat, Nooshin Dalili, Shiva Kalantari, Leonard J. Foster , et al. · 2023

Acute rejection (AR) is one of the main predictors of long-term survival of allograft. The development of noninvasive diagnostic biomarkers of AR is an unmet need for the timely detection. This study aimed to identify novel detective bioma…

Immunogenicity and Safety of SpikoGen, an Adjuvanted Recombinant SARS-CoV-2 Spike Protein, as a Heterologous Third Booster Dose in Kidney Transplant Patients: A Single-arm Clinical Trial Open

Mohsen Nafar, Narges Mostafaloo, A. Firouzan, Fatemeh Poorrezagholi, Fariba Samadian , et al. · 2022

The relationship between CT value and clinical outcomes in renal patients with COVID-19 Open

Sadra Ashrafi, Pouya Pourahmad Kisomi, Saman Maroufizadeh, Mohammad Reza Jabbari, Mohsen Nafar , et al. · 2022

Frequency of CD39+, LAG3+, and CTLA4+ Regulatory T Cells in Two Different Immunosuppressive Protocols in Renal Allograft Recipients (Sirolimus vs Mycophenolate mofetil): A Cohort Report. Open

Yaghoub Mollaei‐Kandelous, Pedram Ahmadpoor, Mohsen Nafar, Mohammad Reza Khatami, Samad Farashi Bonab , et al. · 2022

it seems that both treatment regimen protocols with a low dose ATG induction therapy may be clinically applicable in kidney transplant recipients.

Influence of cytotoxic T lymphocyte antigen 4 genetic variants on acute rejection in kidney transplant patients: precision medicine perspective Open

Andia Taleb, Mahdi Afshari, Mohammad Samzadeh, Negar Sarhangi, Mohsen Nafar , et al. · 2021

Association of IL-15 and IP-10 Serum Levels with Cytomegalovirus Infection, CMV Viral Load and Cyclosporine Level after Kidney Transplantation Open

Reza Asadzadeh, Pedram Ahmadpoor, Mohsen Nafar, Shima Samavat, Hassan Nikoueinejad , et al. · 2021

The levels of IP-10 and IL-15 cytokines are not affected with CMV infection, even if a viral infection occurs in the early days after transplantation or long afterwards. In addition, taking the different levels of cyclosporine did not affe…

Predictive Biomarker Panel in Proliferative Lupus Nephritis- Two-Dimensional Shotgun Proteomics. Open

Mohsen Ghasemi, Shiva Kalantari, Roman A. Zubarev, Mohsen Nafar, Amir Ata Saei , et al. · 2021

Our suggested panel of plasma and urine biomarkers can precisely discriminate patients with possibility of complete response to treatment. It seems that the higher indices of inflammation will associate with better chance of achieving comp…

Agreement between the results of tuberculin skin test and Interferon-Gamma Release Assays in renal transplant candidates Open

Shiva Samavat, Sam Alahyari, Ali Sangian, Malihe Nasiri, Mohsen Nafar , et al. · 2021

Introduction: Identification of latent tuberculosis (TB) infection is important in kidney transplant candidates. Due to the absence of a gold standard, both tuberculin skin test (TST) and interferon-gamma release assays (IGRA) are used to …

Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine. Open

Mohsen Nafar, Nooshin Dalili, Shiva Samavat · 2020

Membranous nephropathy (MN) as one of the most common glomerulonephritis still relies on an invasive procedure of kidney biopsy for precise recognition. Over the recent past years noninvasive methods using wide range of biomarkers have bee…

Low rate of COVID‐19 pneumonia in kidney transplant recipients—A battle between infection and immune response? Open

Maryam Ghaffari Rahbar, Mohsen Nafar, Alireza Khoshdel, Nooshin Dalili, Alireza Abrishami , et al. · 2020

Background With COVID‐19 pandemic, concerns about kidney transplant recipients are rising. However, the incidence, clinical course, outcome, and predictive factors of disease severity are obscured. Methods We describe clinical and laborato…

A Triple-Blind Randomized Controlled Trial on Impacts of Pioglitazone on Oxidative Stress Markers in Diabetic Kidney Transplant Recipients Open

Ali Kharazmkia, Shadi Ziaie, Pedram Ahmadpoor, Omid Moradi, Alireza Khoshdel , et al. · 2020

Background: Oxidative stress as a major mediator of adverse outcomes in kidney transplant recipients who are prone to oxidative stress-mediated injury by pre-transplant and post-transplant conditions. Objectives: The purpose of this study …

Adding Colchicine to the Antiretroviral Medication - Lopinavir/Ritonavir (Kaletra) in Hospitalized Patients with Non-Severe Covid-19 Pneumonia: A Structured Summary of a Study Protocol for a Randomized Controlled Trial Open

Nooshin Dalili, Alireza Kashefizadeh, Mohsen Nafar, Fatemeh Poorrezagholi, A. Firouzan , et al. · 2020

P1738COULD ADDING BORTEZOMIB HAVE BENEFIT FOR ANTIBODY MEDIATED REJECTION AFTER KIDNEY TRANSPLANTATION? Open

Nooshin Dalili, Mohsen Nafar · 2020

Background and Aims Antibody Mediated Rejection (ABMR) is a severe complication that frequently occurs after kidney transplantation. The present RCT designed to evaluate the role of adding Bortezomib to standard regimen with plasma exchang…

SO015URINE NMR-BASED METABOLOMICS FOR EARLY DETECTION OF POST-PROCEDURAL CONTRAST NEPHROPATHY Open

Nooshin Dalili, Shiva Kalantari, Mohsen Nafar · 2020

Background and Aims Contrast induced nephropathy (CIN) has been reported to be the third foremost cause of acute renal failure. Metabolomics is a robust technique that has been used to identify potential biomarkers for early detection of r…

Methylation of the PKD1 Promoter Inversely Correlates with its Expression in Autosomal Dominant Polycystic Kidney Disease Open

Fatemeh Hajirezaei, Sayyed Mohammad Hossein Ghaderian, Mandana Hasanzad, Mohsen Nafar, Mohammad Hassan Ghadiani , et al. · 2020

Methylation of the PKD1 promoter in ADPKD patients was inversely correlated with PKD1 expression.

Living or deceased-donor kidney transplant: the role of psycho-socioeconomic factors and outcomes associated with each type of transplant Open

Abbas Basiri, Maryam Taheri, Alireza Khoshdel, Shabnam Golshan, Hamed Mohseni Rad , et al. · 2020

Background Kidney transplant improves patients’ survival and quality of life. Worldwide, concern about the equality of access to the renal transplant wait-list is increasing. In Iran, patients have the choice to be placed on either the liv…

Clinical Course, Imaging Features, and Outcomes of COVID-19 in Kidney Transplant Recipients Open

Alireza Abrishami, Shiva Samavat, Behdad Behnam, Mehran Arab Ahmadi, Mohsen Nafar , et al. · 2020

Perspective of 20 Years Hemodialysis Registry in Iran, on the Road to Progress. Open

Mohsen Nafar, Mohammad Aghighi, Nooshin Dalili, Behrang Alipour Abedi · 2020

End-stage renal disease (ESRD) is a foremost health issue with major consequences in various parts of the world. In Iran, the prevalence/incidence of ESRD has increased during the past decades. The economic burden of ESRD treatment on pati…

SAT-235 FIRST EXPERIENCE OF ON-LINE HEMODIAFILTRATION IN IRAN; STATE OF THE ART Open

Nooshin Dalili, Mohsen Nafar · 2020

Hemodialysis techniques are based on the ability of molecules to diffuse across a semipermeable membrane, which allows adequate clearance of low molecular weight particles. Combining diffusive and convective transport through hemodiafiltra…

SUN-031 URINE NMR‑BASED METABOLOMICS FOR EARLY DETECTION OF POST PROCEDURAL CONTRAST‑INDUCED NEPHROPATHY Open

Nooshin Dalili, Shiva Kalantari, Mohsen Nafar, Shiva Samavat, Seyed Ali Jamalian · 2020

Contrast induced nephropathy (CIN) has been reported to be the third foremost cause of acute renal failure. Metabolomics is a robust technique that has been used to identify potential biomarkers for early detection of renal damage after pr…

SAT-330 COULD ADDING BORTEZOMIB HAVE BENEFIT FOR ANTIBODY MEDIATED REJECTION AFTER KIDNEY TRANSPLANTATION? Open

Nooshin Dalili, Mohsen Nafar, Mary Panahandeh, P. Navid · 2020

Antibody Mediated Rejection (ABMR) is a severe complication that frequently occurs after kidney transplantation. The present RCT designed to evaluate the role of adding Bortezomib to standard regimen with plasma exchange, intravenous immun…

SAT-329 CORRELATION BETWEEN ESTIMATED GFR AND MEASURED GFR WITH DTPA RENAL SCAN IN LIVING KIDNEY DONORS Open

Shiva Samavat, Mohsen Nafar, Samaneh Hoseinzadeh, H. Masroor, Nooshin Dalili · 2020

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