Molline Timbwa
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View article: Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia
Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia Open
View article: “Though there are some challenges, we try our best to follow the guidelines”: a qualitative study exploring determinants of providing guideline-adherent care to hospitalized children in Kenya
“Though there are some challenges, we try our best to follow the guidelines”: a qualitative study exploring determinants of providing guideline-adherent care to hospitalized children in Kenya Open
View article: Aflatoxin exposure and mortality in acutely ill children: results from the CHAIN network cohort
Aflatoxin exposure and mortality in acutely ill children: results from the CHAIN network cohort Open
Background Chronic exposure to aflatoxins is associated with liver cancer, impaired child growth, and compromised immune function. The Childhood Acute Illness and Nutrition (CHAIN) Network cohort was established to identify risk factors fo…
View article: Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia
Inflammation impairs post-hospital discharge growth among children hospitalised with acute illness in sub-Saharan Africa and south Asia Open
Childhood growth can be affected by acute illness, chronic conditions, diet and their home environment. In resource-poor settings, children often experience poor growth following illness, but the mechanisms are poorly understood. This coho…
View article: Catastrophic expenditure associated with childhood hospitalisation for acute illness in Kenya and Uganda: a cross-sectional study
Catastrophic expenditure associated with childhood hospitalisation for acute illness in Kenya and Uganda: a cross-sectional study Open
Introduction Childhood illness and hospitalisation result in both direct and indirect costs to families before, during and after admission. We aimed to estimate the catastrophic expenditure during hospitalisation for children with acute il…
View article: Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV
Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV Open
View article: Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial
Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial Open
Background Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety and efficacy in chemoprevention. Previous chemoprevention random…
View article: Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV
Systemic biological mechanisms underpin poor post-discharge growth among severely wasted children with HIV Open
In sub-Saharan Africa, children with severe malnutrition (SM) and comorbid HIV (HIV-SM) have substantially worse outcomes than children with SM alone, facing higher mortality risk and impaired nutritional recovery post-hospitalisation. The…
View article: Childhood growth during recovery from acute illness in Africa and South Asia: a secondary analysis of the childhood acute illness and nutrition (CHAIN) prospective cohort
Childhood growth during recovery from acute illness in Africa and South Asia: a secondary analysis of the childhood acute illness and nutrition (CHAIN) prospective cohort Open
Bill & Melinda Gates FoundationOPP1131320; National Institute for Health ResearchNIHR201813.
View article: Effects of the COVID-19 pandemic on hospital admissions and inpatient mortality in Kenya
Effects of the COVID-19 pandemic on hospital admissions and inpatient mortality in Kenya Open
Background The impact of COVID-19 in Africa remains poorly defined. We sought to describe trends in hospitalisation due to all medical causes, pneumonia-specific admissions, and inpatient mortality in Kenya before and during the first five…
View article: A mixed method multi-country assessment of barriers to implementing pediatric inpatient care guidelines
A mixed method multi-country assessment of barriers to implementing pediatric inpatient care guidelines Open
Assessed hospitals had the infrastructure and equipment to implement guideline-consistent care. While fluids, appropriate antimalarials and antibiotics, and malnutrition refeeding adherence was comparable to published estimates from low- a…
View article: Linear growth following complicated severe malnutrition: 1-year follow-up cohort of Kenyan children
Linear growth following complicated severe malnutrition: 1-year follow-up cohort of Kenyan children Open
Background Stunting is the most common manifestation of childhood undernutrition worldwide. Children presenting with severe acute malnutrition (SAM) are often also severely stunted. We evaluated linear growth and its determinants after med…
View article: Changes in susceptibility to life-threatening infections after treatment for complicated severe malnutrition in Kenya
Changes in susceptibility to life-threatening infections after treatment for complicated severe malnutrition in Kenya Open
View article: The impact of rickets on growth and morbidity during recovery among children with complicated severe acute malnutrition in Kenya: A cohort study
The impact of rickets on growth and morbidity during recovery among children with complicated severe acute malnutrition in Kenya: A cohort study Open
The effects of rickets on children recovery from severe acute malnutrition (SAM) are unknown. Rickets may affect both growth and susceptibility to infectious diseases. We investigated the associations of clinically diagnosed rickets with l…
View article: Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised placebo-controlled trial
Daily co-trimoxazole prophylaxis to prevent mortality in children with complicated severe acute malnutrition: a multicentre, double-blind, randomised placebo-controlled trial Open