Molly Bassette
YOU?
Author Swipe
View article: Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors
Multimodal delineation of a layer of effector function among exhausted CD8 T cells in tumors Open
The anti-tumor function of CD8 T cells is limited through well-established pathways of T cell exhaustion (T EX ). Strategies to capture emergent functional states amongst this dominant trajectory of dysfunction are necessary to find pathwa…
View article: Local immune checkpoint blockade therapy by an adenovirus encoding a novel PD-L1 inhibitory peptide inhibits the growth of colon carcinoma in immunocompetent mice
Local immune checkpoint blockade therapy by an adenovirus encoding a novel PD-L1 inhibitory peptide inhibits the growth of colon carcinoma in immunocompetent mice Open
View article: Engineering complex communities by directed evolution
Engineering complex communities by directed evolution Open
View article: Beta-1,3 Oligoglucans Specifically Bind to Immune Receptor CD28 and May Enhance T Cell Activation
Beta-1,3 Oligoglucans Specifically Bind to Immune Receptor CD28 and May Enhance T Cell Activation Open
Beta glucans are known to have immunomodulatory effects that mediated by a variety of mechanisms. In this article, we describe experiments and simulations suggesting that beta-1,3 glucans may promote activation of T cells by a previously u…
View article: Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders
Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders Open
View article: Top-down engineering of complex communities by directed evolution
Top-down engineering of complex communities by directed evolution Open
Directed evolution has been used for decades to engineer biological systems from the top-down. Generally, it has been applied at or below the organismal level, by iteratively sampling the mutational landscape in a guided search for genetic…
View article: Causes, Diagnostics, and Distribution of an Ongoing Penaeid Shrimp Black Gill Epidemic in the U.S. South Atlantic Bight
Causes, Diagnostics, and Distribution of an Ongoing Penaeid Shrimp Black Gill Epidemic in the U.S. South Atlantic Bight Open
Penaeid shrimp including Litopenaeus setiferus (white shrimp), Farfantepenaeus aztecus (brown shrimp), and Farfantepenaeus duorarum (pink shrimp) support one of the most valuable commercial fisheries in the U.S. Southeast Atlantic. Since t…